Click here to switch to the map view.

The map label for this gene is tldD [C]

Identifier: 75909923

GI number: 75909923

Start: 4629189

End: 4630625

Strand: Direct

Name: tldD [C]

Synonym: Ava_3719

Alternate gene names: 75909923

Gene position: 4629189-4630625 (Clockwise)

Preceding gene: 75909922

Following gene: 75909924

Centisome position: 72.72

GC content: 44.4

Gene sequence:

>1437_bases
ATGTGGTCAGAATTAACAAAAGCGATCGCTAGTTTTAAAATACCTGCCGATTGGATCGGTATTCGGGTAGTAAAGGAAAT
TGCTGCTAACCATTATGTCCGTGATGGTTTACCTCAAAGCAACGGTAAATCAACCACAGTCGGAGCCATGTTAGAAGTTT
TGGTGAATGGTTCCTTGGGTTATGCAGCTACCAACTCCCTAGAATTACCATCGTTGCAAGCGGCGGCTGAAATCGCCTAT
AAACAAGCACTAGCAGCCAGTCAGTGGGGCATATATCCTTTCCGTGAAACTGAACGCCCCAAAGTTGTGGGTGAATATAA
CTCCCCATTTTTAGAACCATTGGATGCTCTCAGTCCTGGGGAAATTAATGATTTGTTGGTGCGAATTTGCCACACCTTAA
AAGTTGACGAAAAAATTGTCCAAACCACCGCCAGCGCCTCCACCAGTGAAAAACAGAGTTGGTTTGTCAGCAGCAACGGT
TCTCAGGTATATCAAAAATTCTTGTCCATAGGTACTCATTATGGCGCGATCGCTCAAGATGGGGCGATCGTTCAACAACG
TAGCAATAACGGCTGGCAAGCACACTGTTACCAAGGTGGACTAGAACTGTTAAAACAAGACCACCTATGGCAAAGAGTAC
AGCAAATAGGCGAACAAGCCATAGAACTCTTAACCGCCGAAGAATGTCCAAGCACCCGCACCCATTTGGTTTTAGCCCCA
GACCAAATGATGTTACAAATTCATGAAAGTGTAGGACATCCCTTAGAAATTGACAGAATTTTGGGCGATGAGCGTAACTA
TGCTGGTGGTAGCTTTGTCAACACCAGCGATTTTGGCAAACTAGTCTATGGTTCGCCATTAATGAATATCACCTTTGACC
CCACCGTTGCCGGCGAATATGCCAGCTATGGTTTTGATGATACAGGAGTAGTTGCCACAAGAGAATATGTCATCAAAGAA
GGTGTATTAAAAAGGGGTCTAGGCAGTTTAGAAAGCCAAGCCAGAGCCAAAGTTCCAGGGGTAGCCTGCGCCCGCGCTTC
CTCATGGAATCGACCACCAATTGACCGCATGGCAAACTTAAACTTAGAACCAGGAAACGCTTCCTTTGATGAGATTATCA
GGGATATAGAACACGGCGTGTATATGGAATCTAATCGTTCCTGGTCAATAGACGATCGCCGTTATAAATTTCAGTTTGGC
TGTGAGTATGCCAAACTCATTGAAAATGGTAAGCTAACCAAAACCCTTCGTAATCCTAACTATCGAGCCACAACACCAGA
ATTTTGGCATAGCCTAGTACAAATCAGTGACGATGCTAACTGGCAAATTTACGGTACACCTTTCTGTGGTAAAGGCGAAC
CAAATCAATCTATTTGGGTAGGACATGGTTCACCTGTTTGTGTATTTGCTGATGTAGAAGTTTTTGGGGGAGGATAA

Upstream 100 bases:

>100_bases
TGGGGACTGGGGACTGGGAAAGAGAAAATTCACCCAATACCTAATCCCCAATACCCAATACCTAATCCCCAATACCCAAT
CCCTATTCCCTAATTTTGTT

Downstream 100 bases:

>100_bases
TCAATTCAAAATTCAAAATTCAAAATTCAAAATACCCTACGGGAAGCTAAAGCTACAAAATTCAAAATTTCATGTTGCCC
TCTATTCCTTTTTGATATCC

Product: peptidase U62, modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MWSELTKAIASFKIPADWIGIRVVKEIAANHYVRDGLPQSNGKSTTVGAMLEVLVNGSLGYAATNSLELPSLQAAAEIAY
KQALAASQWGIYPFRETERPKVVGEYNSPFLEPLDALSPGEINDLLVRICHTLKVDEKIVQTTASASTSEKQSWFVSSNG
SQVYQKFLSIGTHYGAIAQDGAIVQQRSNNGWQAHCYQGGLELLKQDHLWQRVQQIGEQAIELLTAEECPSTRTHLVLAP
DQMMLQIHESVGHPLEIDRILGDERNYAGGSFVNTSDFGKLVYGSPLMNITFDPTVAGEYASYGFDDTGVVATREYVIKE
GVLKRGLGSLESQARAKVPGVACARASSWNRPPIDRMANLNLEPGNASFDEIIRDIEHGVYMESNRSWSIDDRRYKFQFG
CEYAKLIENGKLTKTLRNPNYRATTPEFWHSLVQISDDANWQIYGTPFCGKGEPNQSIWVGHGSPVCVFADVEVFGGG

Sequences:

>Translated_478_residues
MWSELTKAIASFKIPADWIGIRVVKEIAANHYVRDGLPQSNGKSTTVGAMLEVLVNGSLGYAATNSLELPSLQAAAEIAY
KQALAASQWGIYPFRETERPKVVGEYNSPFLEPLDALSPGEINDLLVRICHTLKVDEKIVQTTASASTSEKQSWFVSSNG
SQVYQKFLSIGTHYGAIAQDGAIVQQRSNNGWQAHCYQGGLELLKQDHLWQRVQQIGEQAIELLTAEECPSTRTHLVLAP
DQMMLQIHESVGHPLEIDRILGDERNYAGGSFVNTSDFGKLVYGSPLMNITFDPTVAGEYASYGFDDTGVVATREYVIKE
GVLKRGLGSLESQARAKVPGVACARASSWNRPPIDRMANLNLEPGNASFDEIIRDIEHGVYMESNRSWSIDDRRYKFQFG
CEYAKLIENGKLTKTLRNPNYRATTPEFWHSLVQISDDANWQIYGTPFCGKGEPNQSIWVGHGSPVCVFADVEVFGGG
>Mature_478_residues
MWSELTKAIASFKIPADWIGIRVVKEIAANHYVRDGLPQSNGKSTTVGAMLEVLVNGSLGYAATNSLELPSLQAAAEIAY
KQALAASQWGIYPFRETERPKVVGEYNSPFLEPLDALSPGEINDLLVRICHTLKVDEKIVQTTASASTSEKQSWFVSSNG
SQVYQKFLSIGTHYGAIAQDGAIVQQRSNNGWQAHCYQGGLELLKQDHLWQRVQQIGEQAIELLTAEECPSTRTHLVLAP
DQMMLQIHESVGHPLEIDRILGDERNYAGGSFVNTSDFGKLVYGSPLMNITFDPTVAGEYASYGFDDTGVVATREYVIKE
GVLKRGLGSLESQARAKVPGVACARASSWNRPPIDRMANLNLEPGNASFDEIIRDIEHGVYMESNRSWSIDDRRYKFQFG
CEYAKLIENGKLTKTLRNPNYRATTPEFWHSLVQISDDANWQIYGTPFCGKGEPNQSIWVGHGSPVCVFADVEVFGGG

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=425, Percent_Identity=24.2352941176471, Blast_Score=93, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 52790; Mature: 52790

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWSELTKAIASFKIPADWIGIRVVKEIAANHYVRDGLPQSNGKSTTVGAMLEVLVNGSLG
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCC
YAATNSLELPSLQAAAEIAYKQALAASQWGIYPFRETERPKVVGEYNSPFLEPLDALSPG
CEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCHHHHHHCCCCC
EINDLLVRICHTLKVDEKIVQTTASASTSEKQSWFVSSNGSQVYQKFLSIGTHYGAIAQD
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHCCCCCCCCCC
GAIVQQRSNNGWQAHCYQGGLELLKQDHLWQRVQQIGEQAIELLTAEECPSTRTHLVLAP
CCEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
DQMMLQIHESVGHPLEIDRILGDERNYAGGSFVNTSDFGKLVYGSPLMNITFDPTVAGEY
HHHHHHHHHHCCCCEEEHHHHCCCCCCCCCCCCCCCCCCCEEECCCEEEEEECCCCCCCH
ASYGFDDTGVVATREYVIKEGVLKRGLGSLESQARAKVPGVACARASSWNRPPIDRMANL
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHCC
NLEPGNASFDEIIRDIEHGVYMESNRSWSIDDRRYKFQFGCEYAKLIENGKLTKTLRNPN
CCCCCCCCHHHHHHHHHCCEEEECCCCCCCCCCEEEEEECCHHHHHHCCCCEEEHHCCCC
YRATTPEFWHSLVQISDDANWQIYGTPFCGKGEPNQSIWVGHGSPVCVFADVEVFGGG
CCCCCHHHHHHHHEECCCCCEEEEECCCCCCCCCCCCEEEECCCCEEEEEEEEEECCC
>Mature Secondary Structure
MWSELTKAIASFKIPADWIGIRVVKEIAANHYVRDGLPQSNGKSTTVGAMLEVLVNGSLG
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCC
YAATNSLELPSLQAAAEIAYKQALAASQWGIYPFRETERPKVVGEYNSPFLEPLDALSPG
CEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCHHHHHHCCCCC
EINDLLVRICHTLKVDEKIVQTTASASTSEKQSWFVSSNGSQVYQKFLSIGTHYGAIAQD
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHCCCCCCCCCC
GAIVQQRSNNGWQAHCYQGGLELLKQDHLWQRVQQIGEQAIELLTAEECPSTRTHLVLAP
CCEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
DQMMLQIHESVGHPLEIDRILGDERNYAGGSFVNTSDFGKLVYGSPLMNITFDPTVAGEY
HHHHHHHHHHCCCCEEEHHHHCCCCCCCCCCCCCCCCCCCEEECCCEEEEEECCCCCCCH
ASYGFDDTGVVATREYVIKEGVLKRGLGSLESQARAKVPGVACARASSWNRPPIDRMANL
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHCC
NLEPGNASFDEIIRDIEHGVYMESNRSWSIDDRRYKFQFGCEYAKLIENGKLTKTLRNPN
CCCCCCCCHHHHHHHHHCCEEEECCCCCCCCCCEEEEEECCHHHHHHCCCCEEEHHCCCC
YRATTPEFWHSLVQISDDANWQIYGTPFCGKGEPNQSIWVGHGSPVCVFADVEVFGGG
CCCCCHHHHHHHHEECCCCCEEEEECCCCCCCCCCCCEEEECCCCEEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]