Click here to switch to the map view.

The map label for this gene is pab [H]

Identifier: 75909674

GI number: 75909674

Start: 4300375

End: 4302519

Strand: Direct

Name: pab [H]

Synonym: Ava_3468

Alternate gene names: 75909674

Gene position: 4300375-4302519 (Clockwise)

Preceding gene: 75909673

Following gene: 75909675

Centisome position: 67.56

GC content: 44.1

Gene sequence:

>2145_bases
ATGGGCGATATCAAAACACTAATTATTGACAACTACGACTCTTATACTTTTAATCTCTACCAGATGATTGCTGAAGTCAA
CGGAGAGTTGCCCCTTGTTATTCATAATGACAAATTAGACTGGTACGAATTAAAACAACTTGTTTTTGATAATATAGTTA
TTTCTCCTGGGCCTGGTCGTCCTGAAAACCTAAAAGATTTTGGTATTTGTCAACAGATACTACAAAACTATTTAGATGTT
CCCTTACTTGGTGTTTGCCTTGGTCATCAAGGAATTGGTCATTATTATGGTGGTAAGGTAATCCACGCACCAGAACCTCA
ACATGGTCGATTGAGCGATGTTTATCACAGTGGTGGTGATTTATTCCAAGAAATTCCTACACCTTTCTCTGTTGTTCGTT
ATCATTCTTTGCTAGTTGCTGAAGAATTGCCCAGTTGTTTAGAAAAAGTAGCATGGACTGAAGACGGGTTGGTGATGGGG
TTGCGTCATCGTCATTTGCCATTGTGGGGGGTGCAGTTTCATCCAGAATCTATCTGTAGCGAGTATGGATATAAACTTCT
GGAAAACTTCCAAGGTATTACTGAAGAATTCATCCGCCAAAATGGTAGACATCGCCCCAAATTAGAAGGCAAAATTTTCT
CTATTTCTCCTAACTCACCTACTCCAGCGCCACCCCAAGAATTTACTGTTTGTAGTCGAAAATTAGATTATTACCCCGAT
ACAGAACAAGCATTTGTCCACCTTTTTGGTGAAGATCCTCATGCTTTTTGGCTTGATAGTAGCTTTGTAGAACCAGGATT
ATCCCGTTTCTCTTTTATGGGGGGAAGCGGGGGGAAAAACAGTTTACTCGTTTCTTACTGCACCCAATCTCAAGAACTGA
CGATTACACAATCGGGTGAGGTGACACGCACTCAAGAGAGTATTTTTGACTATCTCAAACGAGAAATTAATCGTCGCCGT
TGCCCATCTGATGAGCTACCCTTTGATTTCAATTGTGGTTTTGTGGGCTACTTTGGTTATGAACTTAAGGCAGAATCCGG
GTCTGGGTTAGAACATCCCTCATCATGTCCCGATGCTATCTTGCTTTTAAGCGATCGCCTGATTGCTTTTGACCACCAAG
AGCAAACCACTTACTTAGTTTACCTCGCCCCTGTGGGTGAAACTGCACCAGCTAAAGATTGGTTTGAGATAACTGAGAAA
CGTCTGCGGACACTCCCACCTCTTCCTCCCCTCGTCCCTAGTACTACATCTCACCCCGTTACTTTCCGTTTAAGTCGGTC
ATACCAGACATACAAAGATGATATTTCCAGGTGTCTCAAAGAAATTCGTGAGGGGGAAACTTACCAAGTCTGCCTGACTA
ATCAATTACGCACAGACACAACTACTGATCCACTGACATTTTATCGCCGATTACGCCAAGTTAATCCGGCTCCCTACTCT
GCTTTTCTACGCTTTGGGGAGATGGCGATCGCCTGTTCTTCCCCGGAGCGATTTCTGCAAATTGACCGTCAAGGCTGGGT
AGAAACCAAGCCGATCAAAGGTACTGTACGCCGGGGAGAGACTCCCGAAGAAGATTTTTTACTCCGGGAGAGTTTGCGTA
GCAGCGAAAAAGAACAAGCTGAAAACTTGATGATTGTTGATTTATTACGCAACGATTTAGGGCGAGTTTGTCAAGTCGGG
AGTATCCATGTTCCCAAATTAATGGATGTAGAAAGTTACGCGACGGTGCATCAACTTGTCAGTACTATCCGTGGTTTCTT
ATCCCCCGACATGGACGCAACCGACTGCATCCGGATGGCATTTCCCGGCGGCTCTATGACAGGTGCGCCTAAACTGAGAA
CTATGGAGATTATTGATCAACTTGAGCAAGAGGCGCGGGGAGTTTATTCTGGGGCGATCGGTTTTTTGGGTGTAAACGGT
GCAGCCGACTTGAATATTGTCATTCGTACCGCCGTGCTGACACCAAATCAAACTTCTATAGGGATTGGGGGTGGGATTGT
CGCACTCTCTGAGGTGGAAATGGAATTTCAGGAAACTATCCTCAAAGCTGATGCTTTAATTCAGGCGATGCTCTTAACTG
TTCACGGAGAATATCATCCCAGTCTCTACCGCATTTTAGGAATGCCAACAGAGGTTTTCTGTTGA

Upstream 100 bases:

>100_bases
ATCTAAGCCCGTAGATCCAGATGCTTTAATTGAGGCGATCGGTAATTTGGTCAATAATCAATAAGTGCGTGAATGCAACT
TCTGGTTATCTATTATTCAA

Downstream 100 bases:

>100_bases
GACTAGATATAAGGGTTTTCACTGATTTAAATTTCCAGACTTGCTGCTAAATTTCTTTGAGGTTTTCCTATGCCAATTTA
TGTTTACTGGGGTGAGGATG

Product: anthranilate synthase, component II

Products: NA

Alternate protein names: P-aminobenzoic acid synthase; PABA synthase [H]

Number of amino acids: Translated: 714; Mature: 713

Protein sequence:

>714_residues
MGDIKTLIIDNYDSYTFNLYQMIAEVNGELPLVIHNDKLDWYELKQLVFDNIVISPGPGRPENLKDFGICQQILQNYLDV
PLLGVCLGHQGIGHYYGGKVIHAPEPQHGRLSDVYHSGGDLFQEIPTPFSVVRYHSLLVAEELPSCLEKVAWTEDGLVMG
LRHRHLPLWGVQFHPESICSEYGYKLLENFQGITEEFIRQNGRHRPKLEGKIFSISPNSPTPAPPQEFTVCSRKLDYYPD
TEQAFVHLFGEDPHAFWLDSSFVEPGLSRFSFMGGSGGKNSLLVSYCTQSQELTITQSGEVTRTQESIFDYLKREINRRR
CPSDELPFDFNCGFVGYFGYELKAESGSGLEHPSSCPDAILLLSDRLIAFDHQEQTTYLVYLAPVGETAPAKDWFEITEK
RLRTLPPLPPLVPSTTSHPVTFRLSRSYQTYKDDISRCLKEIREGETYQVCLTNQLRTDTTTDPLTFYRRLRQVNPAPYS
AFLRFGEMAIACSSPERFLQIDRQGWVETKPIKGTVRRGETPEEDFLLRESLRSSEKEQAENLMIVDLLRNDLGRVCQVG
SIHVPKLMDVESYATVHQLVSTIRGFLSPDMDATDCIRMAFPGGSMTGAPKLRTMEIIDQLEQEARGVYSGAIGFLGVNG
AADLNIVIRTAVLTPNQTSIGIGGGIVALSEVEMEFQETILKADALIQAMLLTVHGEYHPSLYRILGMPTEVFC

Sequences:

>Translated_714_residues
MGDIKTLIIDNYDSYTFNLYQMIAEVNGELPLVIHNDKLDWYELKQLVFDNIVISPGPGRPENLKDFGICQQILQNYLDV
PLLGVCLGHQGIGHYYGGKVIHAPEPQHGRLSDVYHSGGDLFQEIPTPFSVVRYHSLLVAEELPSCLEKVAWTEDGLVMG
LRHRHLPLWGVQFHPESICSEYGYKLLENFQGITEEFIRQNGRHRPKLEGKIFSISPNSPTPAPPQEFTVCSRKLDYYPD
TEQAFVHLFGEDPHAFWLDSSFVEPGLSRFSFMGGSGGKNSLLVSYCTQSQELTITQSGEVTRTQESIFDYLKREINRRR
CPSDELPFDFNCGFVGYFGYELKAESGSGLEHPSSCPDAILLLSDRLIAFDHQEQTTYLVYLAPVGETAPAKDWFEITEK
RLRTLPPLPPLVPSTTSHPVTFRLSRSYQTYKDDISRCLKEIREGETYQVCLTNQLRTDTTTDPLTFYRRLRQVNPAPYS
AFLRFGEMAIACSSPERFLQIDRQGWVETKPIKGTVRRGETPEEDFLLRESLRSSEKEQAENLMIVDLLRNDLGRVCQVG
SIHVPKLMDVESYATVHQLVSTIRGFLSPDMDATDCIRMAFPGGSMTGAPKLRTMEIIDQLEQEARGVYSGAIGFLGVNG
AADLNIVIRTAVLTPNQTSIGIGGGIVALSEVEMEFQETILKADALIQAMLLTVHGEYHPSLYRILGMPTEVFC
>Mature_713_residues
GDIKTLIIDNYDSYTFNLYQMIAEVNGELPLVIHNDKLDWYELKQLVFDNIVISPGPGRPENLKDFGICQQILQNYLDVP
LLGVCLGHQGIGHYYGGKVIHAPEPQHGRLSDVYHSGGDLFQEIPTPFSVVRYHSLLVAEELPSCLEKVAWTEDGLVMGL
RHRHLPLWGVQFHPESICSEYGYKLLENFQGITEEFIRQNGRHRPKLEGKIFSISPNSPTPAPPQEFTVCSRKLDYYPDT
EQAFVHLFGEDPHAFWLDSSFVEPGLSRFSFMGGSGGKNSLLVSYCTQSQELTITQSGEVTRTQESIFDYLKREINRRRC
PSDELPFDFNCGFVGYFGYELKAESGSGLEHPSSCPDAILLLSDRLIAFDHQEQTTYLVYLAPVGETAPAKDWFEITEKR
LRTLPPLPPLVPSTTSHPVTFRLSRSYQTYKDDISRCLKEIREGETYQVCLTNQLRTDTTTDPLTFYRRLRQVNPAPYSA
FLRFGEMAIACSSPERFLQIDRQGWVETKPIKGTVRRGETPEEDFLLRESLRSSEKEQAENLMIVDLLRNDLGRVCQVGS
IHVPKLMDVESYATVHQLVSTIRGFLSPDMDATDCIRMAFPGGSMTGAPKLRTMEIIDQLEQEARGVYSGAIGFLGVNGA
ADLNIVIRTAVLTPNQTSIGIGGGIVALSEVEMEFQETILKADALIQAMLLTVHGEYHPSLYRILGMPTEVFC

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=444, Percent_Identity=35.1351351351351, Blast_Score=232, Evalue=6e-62,
Organism=Escherichia coli, GI1787518, Length=401, Percent_Identity=31.6708229426434, Blast_Score=179, Evalue=8e-46,
Organism=Escherichia coli, GI1789760, Length=186, Percent_Identity=46.2365591397849, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI1787517, Length=214, Percent_Identity=35.5140186915888, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI87082077, Length=255, Percent_Identity=25.4901960784314, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1786809, Length=264, Percent_Identity=24.2424242424242, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324361, Length=795, Percent_Identity=29.685534591195, Blast_Score=244, Evalue=3e-65,
Organism=Saccharomyces cerevisiae, GI6320935, Length=443, Percent_Identity=32.0541760722348, Blast_Score=204, Evalue=3e-53,
Organism=Saccharomyces cerevisiae, GI6322638, Length=191, Percent_Identity=38.2198952879581, Blast_Score=146, Evalue=9e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR006805
- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR015890
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR005802
- InterPro:   IPR006221 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind; PF00117 GATase [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 80379; Mature: 80248

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDIKTLIIDNYDSYTFNLYQMIAEVNGELPLVIHNDKLDWYELKQLVFDNIVISPGPGR
CCCEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCEEECCCCCC
PENLKDFGICQQILQNYLDVPLLGVCLGHQGIGHYYGGKVIHAPEPQHGRLSDVYHSGGD
CCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHCCCEEEECCCCCCCCHHHHHHCCCH
LFQEIPTPFSVVRYHSLLVAEELPSCLEKVAWTEDGLVMGLRHRHLPLWGVQFHPESICS
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHCCCCEEEEEECHHHHHH
EYGYKLLENFQGITEEFIRQNGRHRPKLEGKIFSISPNSPTPAPPQEFTVCSRKLDYYPD
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCC
TEQAFVHLFGEDPHAFWLDSSFVEPGLSRFSFMGGSGGKNSLLVSYCTQSQELTITQSGE
CHHHEEEEECCCCCEEEECCHHHCCCHHHHEECCCCCCCCCEEEEEECCCCEEEEECCCC
VTRTQESIFDYLKREINRRRCPSDELPFDFNCGFVGYFGYELKAESGSGLEHPSSCPDAI
CCHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCEEEEECEEEEECCCCCCCCCCCCCCHH
LLLSDRLIAFDHQEQTTYLVYLAPVGETAPAKDWFEITEKRLRTLPPLPPLVPSTTSHPV
HHHHCCEEEEECCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCE
TFRLSRSYQTYKDDISRCLKEIREGETYQVCLTNQLRTDTTTDPLTFYRRLRQVNPAPYS
EEEECCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCHH
AFLRFGEMAIACSSPERFLQIDRQGWVETKPIKGTVRRGETPEEDFLLRESLRSSEKEQA
HHHHHCCEEEEECCCHHHHHHHCCCCEECCCCCCHHCCCCCCHHHHHHHHHHHCCHHHHH
ENLMIVDLLRNDLGRVCQVGSIHVPKLMDVESYATVHQLVSTIRGFLSPDMDATDCIRMA
HCEEHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHEEEE
FPGGSMTGAPKLRTMEIIDQLEQEARGVYSGAIGFLGVNGAADLNIVIRTAVLTPNQTSI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCEEEEEEEEEECCCCCCC
GIGGGIVALSEVEMEFQETILKADALIQAMLLTVHGEYHPSLYRILGMPTEVFC
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHCC
>Mature Secondary Structure 
GDIKTLIIDNYDSYTFNLYQMIAEVNGELPLVIHNDKLDWYELKQLVFDNIVISPGPGR
CCEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCEEECCCCCC
PENLKDFGICQQILQNYLDVPLLGVCLGHQGIGHYYGGKVIHAPEPQHGRLSDVYHSGGD
CCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHCCCEEEECCCCCCCCHHHHHHCCCH
LFQEIPTPFSVVRYHSLLVAEELPSCLEKVAWTEDGLVMGLRHRHLPLWGVQFHPESICS
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHCCCCEEEEEECHHHHHH
EYGYKLLENFQGITEEFIRQNGRHRPKLEGKIFSISPNSPTPAPPQEFTVCSRKLDYYPD
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCC
TEQAFVHLFGEDPHAFWLDSSFVEPGLSRFSFMGGSGGKNSLLVSYCTQSQELTITQSGE
CHHHEEEEECCCCCEEEECCHHHCCCHHHHEECCCCCCCCCEEEEEECCCCEEEEECCCC
VTRTQESIFDYLKREINRRRCPSDELPFDFNCGFVGYFGYELKAESGSGLEHPSSCPDAI
CCHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCEEEEECEEEEECCCCCCCCCCCCCCHH
LLLSDRLIAFDHQEQTTYLVYLAPVGETAPAKDWFEITEKRLRTLPPLPPLVPSTTSHPV
HHHHCCEEEEECCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCE
TFRLSRSYQTYKDDISRCLKEIREGETYQVCLTNQLRTDTTTDPLTFYRRLRQVNPAPYS
EEEECCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCHH
AFLRFGEMAIACSSPERFLQIDRQGWVETKPIKGTVRRGETPEEDFLLRESLRSSEKEQA
HHHHHCCEEEEECCCHHHHHHHCCCCEECCCCCCHHCCCCCCHHHHHHHHHHHCCHHHHH
ENLMIVDLLRNDLGRVCQVGSIHVPKLMDVESYATVHQLVSTIRGFLSPDMDATDCIRMA
HCEEHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHEEEE
FPGGSMTGAPKLRTMEIIDQLEQEARGVYSGAIGFLGVNGAADLNIVIRTAVLTPNQTSI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCEEEEEEEEEECCCCCCC
GIGGGIVALSEVEMEFQETILKADALIQAMLLTVHGEYHPSLYRILGMPTEVFC
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8472954 [H]