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The map label for this gene is mpg1 [H]

Identifier: 75909628

GI number: 75909628

Start: 4253007

End: 4254176

Strand: Direct

Name: mpg1 [H]

Synonym: Ava_3422

Alternate gene names: 75909628

Gene position: 4253007-4254176 (Clockwise)

Preceding gene: 75909627

Following gene: 75909630

Centisome position: 66.81

GC content: 46.15

Gene sequence:

>1170_bases
ATGAAAGCGATGATTCTCGCAGCAGGTAAGGGTACTCGCGTTCGTCCGATTACCTATACGATTCCCAAACCGATGATTCC
CATCCTGCAAAAGCCAGTGATGGAATTTTTACTGGAACTTTTACGTCAACATGGTTTCGACCAGATTATGGTCAACGTCA
GCCATTTGGCTGAGGAAATTGAAAACTATTTTCGTGATGGTCAACGGTTTGGTGTGCAGATTGCCTATTCTTTTGAAGGC
AAAATTGATGATGAAGGTAAGTTGGTAGGGGAAGCAATAGGTTCTGCTGGAGGGATGCGTCGCATCCAAGATTTTTCACC
ATTTTTTGATGATACCTTTGTGGTGTTGTGTGGCGACGCTTTGATTGACTTAGATTTGACGGCAGCAGTAAAGTGGCATA
AATCCAAAGGTTCCATCGCCACTATCATTACCAAAACTGTCCCCGAAGAAGAAGTTTCTAGTTATGGTGTGGTCGTCACT
GATGAGAATAGTCGGGTTAAAGCCTTCCAAGAAAAACCATCGATAGAAGAAGCACTCAGTACTAATATCAACACAGGTAT
CTACATTTTTGAGCCAGAGGTGTTTAATTACATACCTTCTGGTGTGGAGTATGACATCGGTGGTCAACTATTCCCCAAAC
TGGTAGAAATTGGTGCGCCCTTCTATGCGATCGCAATGGATTTTGAATGGGTGGATATTGGTAAAGTACCAGACTACTGG
CGGGCAATTCGCGGCGTGTTACAAGGGGAAATCAAGAATGTGCAGATTCCCGGTCATGAGGTTGCCCCTGGCATCTACAC
TGGCTTAAATGTGGCGGTGAATTGGGACAAAGTAGATATCACTGGCCCCGTTTACATTGGTGGCATGACTCGCATCGAAG
ATGGCGCGAAAATTGTCGGCCCGGCGATGATTGGCCCCAATTGCTGGATATGTGGTGAAGCTACTGTTGATAACAGTGTC
ATCTTTGAATGGTCACGATTAGGGCATGGAGCCAGGCTAGTAGATAAACTGGTGTTCGGGCGTTACTGTGTTGATAAAAC
AGGAGCTGCCATTGATGTGCAAGCTGCTGCCTTAGATTGGCTGATTACCGATGCGCGGCAAACACCGCCAGAACATACCC
CAGTGGAACGGCAAGCGATCGCCGAATTGTTGGGAACAAACGCAATTTAG

Upstream 100 bases:

>100_bases
TATCCCTGTTGTCAGGGGTTACTTAGAGCAGAAATAAAAAACTGATGATTAAGTATCACACAATGAAAGTAAACTGGCTT
GTGGTTGAGGAATAAACTTT

Downstream 100 bases:

>100_bases
TCAATAGTCATTAGTCAGTTGTCAGTTGCAATTTCTACTGACAACTGACAACTAACCACTGACCACTAACTATTTAAGTA
TGTGTATCTTCTGAGACTTT

Product: nucleotidyl transferase

Products: NA

Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MKAMILAAGKGTRVRPITYTIPKPMIPILQKPVMEFLLELLRQHGFDQIMVNVSHLAEEIENYFRDGQRFGVQIAYSFEG
KIDDEGKLVGEAIGSAGGMRRIQDFSPFFDDTFVVLCGDALIDLDLTAAVKWHKSKGSIATIITKTVPEEEVSSYGVVVT
DENSRVKAFQEKPSIEEALSTNINTGIYIFEPEVFNYIPSGVEYDIGGQLFPKLVEIGAPFYAIAMDFEWVDIGKVPDYW
RAIRGVLQGEIKNVQIPGHEVAPGIYTGLNVAVNWDKVDITGPVYIGGMTRIEDGAKIVGPAMIGPNCWICGEATVDNSV
IFEWSRLGHGARLVDKLVFGRYCVDKTGAAIDVQAAALDWLITDARQTPPEHTPVERQAIAELLGTNAI

Sequences:

>Translated_389_residues
MKAMILAAGKGTRVRPITYTIPKPMIPILQKPVMEFLLELLRQHGFDQIMVNVSHLAEEIENYFRDGQRFGVQIAYSFEG
KIDDEGKLVGEAIGSAGGMRRIQDFSPFFDDTFVVLCGDALIDLDLTAAVKWHKSKGSIATIITKTVPEEEVSSYGVVVT
DENSRVKAFQEKPSIEEALSTNINTGIYIFEPEVFNYIPSGVEYDIGGQLFPKLVEIGAPFYAIAMDFEWVDIGKVPDYW
RAIRGVLQGEIKNVQIPGHEVAPGIYTGLNVAVNWDKVDITGPVYIGGMTRIEDGAKIVGPAMIGPNCWICGEATVDNSV
IFEWSRLGHGARLVDKLVFGRYCVDKTGAAIDVQAAALDWLITDARQTPPEHTPVERQAIAELLGTNAI
>Mature_389_residues
MKAMILAAGKGTRVRPITYTIPKPMIPILQKPVMEFLLELLRQHGFDQIMVNVSHLAEEIENYFRDGQRFGVQIAYSFEG
KIDDEGKLVGEAIGSAGGMRRIQDFSPFFDDTFVVLCGDALIDLDLTAAVKWHKSKGSIATIITKTVPEEEVSSYGVVVT
DENSRVKAFQEKPSIEEALSTNINTGIYIFEPEVFNYIPSGVEYDIGGQLFPKLVEIGAPFYAIAMDFEWVDIGKVPDYW
RAIRGVLQGEIKNVQIPGHEVAPGIYTGLNVAVNWDKVDITGPVYIGGMTRIEDGAKIVGPAMIGPNCWICGEATVDNSV
IFEWSRLGHGARLVDKLVFGRYCVDKTGAAIDVQAAALDWLITDARQTPPEHTPVERQAIAELLGTNAI

Specific function: Glycogen biosynthesis; first step. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=354, Percent_Identity=29.9435028248588, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI11761619, Length=253, Percent_Identity=32.8063241106719, Blast_Score=131, Evalue=1e-30,
Organism=Escherichia coli, GI1789837, Length=265, Percent_Identity=25.2830188679245, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1790224, Length=203, Percent_Identity=26.6009852216749, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788351, Length=196, Percent_Identity=28.0612244897959, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI133931050, Length=346, Percent_Identity=30.635838150289, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17509979, Length=359, Percent_Identity=25.3481894150418, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17509981, Length=348, Percent_Identity=24.7126436781609, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320148, Length=354, Percent_Identity=27.9661016949153, Blast_Score=118, Evalue=2e-27,
Organism=Drosophila melanogaster, GI21355443, Length=334, Percent_Identity=30.5389221556886, Blast_Score=142, Evalue=5e-34,
Organism=Drosophila melanogaster, GI24644084, Length=334, Percent_Identity=30.5389221556886, Blast_Score=142, Evalue=5e-34,
Organism=Drosophila melanogaster, GI24653912, Length=205, Percent_Identity=28.780487804878, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 42810; Mature: 42810

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAMILAAGKGTRVRPITYTIPKPMIPILQKPVMEFLLELLRQHGFDQIMVNVSHLAEEI
CCEEEEECCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHH
ENYFRDGQRFGVQIAYSFEGKIDDEGKLVGEAIGSAGGMRRIQDFSPFFDDTFVVLCGDA
HHHHHCCCEEEEEEEEEECCCCCCCCHHHHHHHCCCCCHHHHHHCCCCCCCEEEEEECCE
LIDLDLTAAVKWHKSKGSIATIITKTVPEEEVSSYGVVVTDENSRVKAFQEKPSIEEALS
EEEEEEEEEEEEECCCCCEEEEEEECCCHHHHHCCCEEEECCCCCCHHHHCCCCHHHHHH
TNINTGIYIFEPEVFNYIPSGVEYDIGGQLFPKLVEIGAPFYAIAMDFEWVDIGKVPDYW
CCCCCCEEEECCHHHHHCCCCCEECCCCHHHHHHHHHCCCEEEEEEEEEEEECCCCCHHH
RAIRGVLQGEIKNVQIPGHEVAPGIYTGLNVAVNWDKVDITGPVYIGGMTRIEDGAKIVG
HHHHHHHHCCCCEEECCCCCCCCCEEECCEEEEEECEEEECCCEEECCCEEECCCCEEEC
PAMIGPNCWICGEATVDNSVIFEWSRLGHGARLVDKLVFGRYCVDKTGAAIDVQAAALDW
CEEECCCEEEECCCCCCCCEEEEHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHH
LITDARQTPPEHTPVERQAIAELLGTNAI
HHCCCCCCCCCCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MKAMILAAGKGTRVRPITYTIPKPMIPILQKPVMEFLLELLRQHGFDQIMVNVSHLAEEI
CCEEEEECCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHH
ENYFRDGQRFGVQIAYSFEGKIDDEGKLVGEAIGSAGGMRRIQDFSPFFDDTFVVLCGDA
HHHHHCCCEEEEEEEEEECCCCCCCCHHHHHHHCCCCCHHHHHHCCCCCCCEEEEEECCE
LIDLDLTAAVKWHKSKGSIATIITKTVPEEEVSSYGVVVTDENSRVKAFQEKPSIEEALS
EEEEEEEEEEEEECCCCCEEEEEEECCCHHHHHCCCEEEECCCCCCHHHHCCCCHHHHHH
TNINTGIYIFEPEVFNYIPSGVEYDIGGQLFPKLVEIGAPFYAIAMDFEWVDIGKVPDYW
CCCCCCEEEECCHHHHHCCCCCEECCCCHHHHHHHHHCCCEEEEEEEEEEEECCCCCHHH
RAIRGVLQGEIKNVQIPGHEVAPGIYTGLNVAVNWDKVDITGPVYIGGMTRIEDGAKIVG
HHHHHHHHCCCCEEECCCCCCCCCEEECCEEEEEECEEEECCCEEECCCEEECCCCEEEC
PAMIGPNCWICGEATVDNSVIFEWSRLGHGARLVDKLVFGRYCVDKTGAAIDVQAAALDW
CEEECCCEEEECCCCCCCCEEEEHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHH
LITDARQTPPEHTPVERQAIAELLGTNAI
HHCCCCCCCCCCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8334170 [H]