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The map label for this gene is ubiE [H]

Identifier: 75909625

GI number: 75909625

Start: 4249652

End: 4250551

Strand: Direct

Name: ubiE [H]

Synonym: Ava_3419

Alternate gene names: 75909625

Gene position: 4249652-4250551 (Clockwise)

Preceding gene: 75909623

Following gene: 75909626

Centisome position: 66.76

GC content: 44.22

Gene sequence:

>900_bases
ATGGCAACACGTCCAAAAACAATTTGGGAAAGCTTCTTATCGCCTGTAGTCCGGTTTTTGATTGATGAAGACAAGTGGCG
GCGTTATGCTCAAAGTATCGATTGGGAAAAAGAAAGCGATCGCTTCCGCAGAACAGATGTGATAATCCCCTCGTACTACA
CTAGCCATAATTTTCACGGCATTGAGGGGGGATATCTCAATTCTAGTGCAGCCGTCACCTACGACCCAATTACGGAATAC
GTCCTACCACCAAATGAAACGCTGGTACGTCAAGCCTTAATTGATGCGGTAAAAGTCCAACCACGACGCATACTTGATTT
AGGTTGTGGTACGGGTTCCACCACATTAATGTTAAAGCAGGCTTTTTCCCAAGCAGATGTGATCGGTTTGGATTTATCAC
CTTATATGTTGGTGAGGGCGGAAGATAAAGCCAGAATTGGGGGTTTAGATATTAGCTGGCGACATGGGAACGCCGAAAAA
ACTAGCTTTCCCGATGCTTCCTTTGATTTGGTGACGGCTGCTTTGTTATTCCATGAGACACCAGTTGAGGTATCCCAAGC
AATATTACAAGAATGTTTCCGGCTGTTGGTAGCTGGTGGACAAGTTATAATTCTCGACGGAAATCAAAAAAGCCTACGTC
AGTTAAATTGGCTCAATGATATTTTTGAGGAGCCTTACATCCGTGAGTATGCGGCTGATAGTGTAGATGCGCGGATGGGT
GCGGCTGGGTTTGCCAAAGTGCGGACAGAAGATTTATGGCTGATACATCAAGTAACTAGCGGTATCAAACCCATCTTGGC
AACAGATACTAACCAAGCAAAAGAAAGACAATATATGGCAGCAATAGATAATAATAATTTGGAGGGTCTAGAATCTCCAG
CTTTTGGCATAGTGGCATGA

Upstream 100 bases:

>100_bases
ACTCGTAGAGTAGCAAGCTATGGAGAGGGGTTTCAAAAATAAGTCGCACATTGCGTACAGTAGAATTTAAAAGAATAATG
ACCGAGCCTAACTCAACTTT

Downstream 100 bases:

>100_bases
GTTTAAAGGCAATTCTGTTTGATTTCAATGGCGTAATCATCAATGATGAGCGCATCCACCTACAATTGATCGATGAAATT
CTCATTCAAGAAAATCTCCA

Product: UbiE/COQ5 methyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MATRPKTIWESFLSPVVRFLIDEDKWRRYAQSIDWEKESDRFRRTDVIIPSYYTSHNFHGIEGGYLNSSAAVTYDPITEY
VLPPNETLVRQALIDAVKVQPRRILDLGCGTGSTTLMLKQAFSQADVIGLDLSPYMLVRAEDKARIGGLDISWRHGNAEK
TSFPDASFDLVTAALLFHETPVEVSQAILQECFRLLVAGGQVIILDGNQKSLRQLNWLNDIFEEPYIREYAADSVDARMG
AAGFAKVRTEDLWLIHQVTSGIKPILATDTNQAKERQYMAAIDNNNLEGLESPAFGIVA

Sequences:

>Translated_299_residues
MATRPKTIWESFLSPVVRFLIDEDKWRRYAQSIDWEKESDRFRRTDVIIPSYYTSHNFHGIEGGYLNSSAAVTYDPITEY
VLPPNETLVRQALIDAVKVQPRRILDLGCGTGSTTLMLKQAFSQADVIGLDLSPYMLVRAEDKARIGGLDISWRHGNAEK
TSFPDASFDLVTAALLFHETPVEVSQAILQECFRLLVAGGQVIILDGNQKSLRQLNWLNDIFEEPYIREYAADSVDARMG
AAGFAKVRTEDLWLIHQVTSGIKPILATDTNQAKERQYMAAIDNNNLEGLESPAFGIVA
>Mature_298_residues
ATRPKTIWESFLSPVVRFLIDEDKWRRYAQSIDWEKESDRFRRTDVIIPSYYTSHNFHGIEGGYLNSSAAVTYDPITEYV
LPPNETLVRQALIDAVKVQPRRILDLGCGTGSTTLMLKQAFSQADVIGLDLSPYMLVRAEDKARIGGLDISWRHGNAEKT
SFPDASFDLVTAALLFHETPVEVSQAILQECFRLLVAGGQVIILDGNQKSLRQLNWLNDIFEEPYIREYAADSVDARMGA
AGFAKVRTEDLWLIHQVTSGIKPILATDTNQAKERQYMAAIDNNNLEGLESPAFGIVA

Specific function: Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004033 [H]

Pfam domain/function: PF01209 Ubie_methyltran [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 33557; Mature: 33426

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATRPKTIWESFLSPVVRFLIDEDKWRRYAQSIDWEKESDRFRRTDVIIPSYYTSHNFHG
CCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHEEEECCCCCCCCCCC
IEGGYLNSSAAVTYDPITEYVLPPNETLVRQALIDAVKVQPRRILDLGCGTGSTTLMLKQ
CCCCEECCCCEEEECCCCCEECCCCHHHHHHHHHHHHHCCCHHEEEECCCCCCHHHHHHH
AFSQADVIGLDLSPYMLVRAEDKARIGGLDISWRHGNAEKTSFPDASFDLVTAALLFHET
HHCCCCEEEECCCCEEEEEECCCCEECCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCC
PVEVSQAILQECFRLLVAGGQVIILDGNQKSLRQLNWLNDIFEEPYIREYAADSVDARMG
CHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHCC
AAGFAKVRTEDLWLIHQVTSGIKPILATDTNQAKERQYMAAIDNNNLEGLESPAFGIVA
CCCHHHCCHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ATRPKTIWESFLSPVVRFLIDEDKWRRYAQSIDWEKESDRFRRTDVIIPSYYTSHNFHG
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHEEEECCCCCCCCCCC
IEGGYLNSSAAVTYDPITEYVLPPNETLVRQALIDAVKVQPRRILDLGCGTGSTTLMLKQ
CCCCEECCCCEEEECCCCCEECCCCHHHHHHHHHHHHHCCCHHEEEECCCCCCHHHHHHH
AFSQADVIGLDLSPYMLVRAEDKARIGGLDISWRHGNAEKTSFPDASFDLVTAALLFHET
HHCCCCEEEECCCCEEEEEECCCCEECCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCC
PVEVSQAILQECFRLLVAGGQVIILDGNQKSLRQLNWLNDIFEEPYIREYAADSVDARMG
CHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHCC
AAGFAKVRTEDLWLIHQVTSGIKPILATDTNQAKERQYMAAIDNNNLEGLESPAFGIVA
CCCHHHCCHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA