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The map label for this gene is cbbY [H]

Identifier: 75909626

GI number: 75909626

Start: 4250548

End: 4251276

Strand: Direct

Name: cbbY [H]

Synonym: Ava_3420

Alternate gene names: 75909626

Gene position: 4250548-4251276 (Clockwise)

Preceding gene: 75909625

Following gene: 75909627

Centisome position: 66.77

GC content: 43.62

Gene sequence:

>729_bases
ATGAGTTTAAAGGCAATTCTGTTTGATTTCAATGGCGTAATCATCAATGATGAGCGCATCCACCTACAATTGATCGATGA
AATTCTCATTCAAGAAAATCTCCAACCCCAAAAAGTGCAAGAGCGTCAAGCTTCATTAGGAAGGAGCGATCGCGCTTGTT
TTCAAGAATTGCTAGCAAATCGTGGTAGAGTCGTCAGCGATGATTCTTTAACTCAGTTACTCAACAGTAAAGCTCAAGCT
TACGTGCTGGAAGTGGAGAAATTAGAAAAACTCCCCATATATCCAGGTCTAGAAGACTTGATATATCAAGCGCGTTCCCG
TAATCTCCATTTAGGCATTGTTAGCGGTGCAGTTCGTCAAGAAATAGAGCTAGTACTTAACCGCGCTAAACTAGCCGAGT
ACTTCACAGTTATTGTTGCAGGCGACGACATCACCACCAGCAAACCCAAACCAGATGGTTATTTACTAGCAGTGGAACGC
CTAAATCAAGAATATCCCGAATTAAATCTCTTACCCCAGGAATGCTTGGCTATTGAAGATACCCCAGCAGGTATCGCAGC
CGCTAAACGAGCGCAAATGCAGGTGGTAGGCGTAGCGAATACATACCCCTTCCATATGTTACAACGCTGCTGTAACTGGA
CTGTCGATTACCTGAGTGACTTGGAACTAGAACGAGTCCAAAAAATATTTTCTGGCGGAGAATTTCAGGCGATCGTGAGT
GAGTGTTAA

Upstream 100 bases:

>100_bases
TGGCAACAGATACTAACCAAGCAAAAGAAAGACAATATATGGCAGCAATAGATAATAATAATTTGGAGGGTCTAGAATCT
CCAGCTTTTGGCATAGTGGC

Downstream 100 bases:

>100_bases
AATATTGTCTAATAGCATGAAGTTAGTCTAGGTAAGCATAATTTTATCAACTTACCAAGCTCTCTAAGGGGAATTAGCTC
AGTTGGTAGAGCGCTGCGAT

Product: HAD family hydrolase

Products: beta-D-glucose 6-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MSLKAILFDFNGVIINDERIHLQLIDEILIQENLQPQKVQERQASLGRSDRACFQELLANRGRVVSDDSLTQLLNSKAQA
YVLEVEKLEKLPIYPGLEDLIYQARSRNLHLGIVSGAVRQEIELVLNRAKLAEYFTVIVAGDDITTSKPKPDGYLLAVER
LNQEYPELNLLPQECLAIEDTPAGIAAAKRAQMQVVGVANTYPFHMLQRCCNWTVDYLSDLELERVQKIFSGGEFQAIVS
EC

Sequences:

>Translated_242_residues
MSLKAILFDFNGVIINDERIHLQLIDEILIQENLQPQKVQERQASLGRSDRACFQELLANRGRVVSDDSLTQLLNSKAQA
YVLEVEKLEKLPIYPGLEDLIYQARSRNLHLGIVSGAVRQEIELVLNRAKLAEYFTVIVAGDDITTSKPKPDGYLLAVER
LNQEYPELNLLPQECLAIEDTPAGIAAAKRAQMQVVGVANTYPFHMLQRCCNWTVDYLSDLELERVQKIFSGGEFQAIVS
EC
>Mature_241_residues
SLKAILFDFNGVIINDERIHLQLIDEILIQENLQPQKVQERQASLGRSDRACFQELLANRGRVVSDDSLTQLLNSKAQAY
VLEVEKLEKLPIYPGLEDLIYQARSRNLHLGIVSGAVRQEIELVLNRAKLAEYFTVIVAGDDITTSKPKPDGYLLAVERL
NQEYPELNLLPQECLAIEDTPAGIAAAKRAQMQVVGVANTYPFHMLQRCCNWTVDYLSDLELERVQKIFSGGEFQAIVSE
C

Specific function: Reversible Transformation Of Glucose 6-Phosphate And Beta-Glucose 1-Phosphate (By Similarity). [C]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1787576, Length=217, Percent_Identity=27.6497695852535, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789787, Length=171, Percent_Identity=27.4853801169591, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: 5.4.2.6

Molecular weight: Translated: 27274; Mature: 27142

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKAILFDFNGVIINDERIHLQLIDEILIQENLQPQKVQERQASLGRSDRACFQELLAN
CCCEEEEEECCCEEECCCEEHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHC
RGRVVSDDSLTQLLNSKAQAYVLEVEKLEKLPIYPGLEDLIYQARSRNLHLGIVSGAVRQ
CCCEECCHHHHHHHHCCHHEEEHHHHHHHCCCCCCCHHHHHHHHHCCCEEEEEHHHHHHH
EIELVLNRAKLAEYFTVIVAGDDITTSKPKPDGYLLAVERLNQEYPELNLLPQECLAIED
HHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCEEEEHHHHCCCCCCCCCCHHHHHEECC
TPAGIAAAKRAQMQVVGVANTYPFHMLQRCCNWTVDYLSDLELERVQKIFSGGEFQAIVS
CCCHHHHHHHHHEEEEEECCCCHHHHHHHHHCCHHHHHHCCCHHHHHHHHCCCCCHHHHH
EC
CC
>Mature Secondary Structure 
SLKAILFDFNGVIINDERIHLQLIDEILIQENLQPQKVQERQASLGRSDRACFQELLAN
CCEEEEEECCCEEECCCEEHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHC
RGRVVSDDSLTQLLNSKAQAYVLEVEKLEKLPIYPGLEDLIYQARSRNLHLGIVSGAVRQ
CCCEECCHHHHHHHHCCHHEEEHHHHHHHCCCCCCCHHHHHHHHHCCCEEEEEHHHHHHH
EIELVLNRAKLAEYFTVIVAGDDITTSKPKPDGYLLAVERLNQEYPELNLLPQECLAIED
HHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCEEEEHHHHCCCCCCCCCCHHHHHEECC
TPAGIAAAKRAQMQVVGVANTYPFHMLQRCCNWTVDYLSDLELERVQKIFSGGEFQAIVS
CCCHHHHHHHHHEEEEEECCCCHHHHHHHHHCCHHHHHHCCCHHHHHHHHCCCCCHHHHH
EC
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: beta-D-glucose 1-phosphate

Specific reaction: beta-D-glucose 1-phosphate = beta-D-glucose 6-phosphate

General reaction: Group transfer (intramolecular phosphate group isomerization [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA