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The map label for this gene is ywoG [H]

Identifier: 75909604

GI number: 75909604

Start: 4226008

End: 4227243

Strand: Direct

Name: ywoG [H]

Synonym: Ava_3398

Alternate gene names: 75909604

Gene position: 4226008-4227243 (Clockwise)

Preceding gene: 75909603

Following gene: 75909605

Centisome position: 66.39

GC content: 43.37

Gene sequence:

>1236_bases
TTGAAAGCTTTTAATACATTTGACGCAAGCTTGCGGCTTAACCTGCTGATTCTATTTACGGCAGGTTTATTGTTCTGGTC
GAGTACTGCTACTTTCTTGCCCACTCTGCCCTTATATATTGAGGATGTGGGAGGAAGCAAGCAAGAAATTGGCATTGTGA
TGGGTGGTTTTGCTATTGGGTTGTTAGTATTTCGCCCAATGCTGGGACGAATGGCGGATCAAAACGGTCGGAAGTTACTG
TTATTAATTGGGACAATAGTGGCAACAATTGCCCCCTTTGGCTATTTGGCATTTAAATCAATTCCTTTATTGATGCTGGT
GCGCGTCTTTCATGGCATTAGCATTGCTGCTTTTACCACTGGTTACAGTGCTTTAATAGCAGATTTAGCCCCTATAGCCA
TTCGTGGTGAAATCATCAGTTACATGAGTCTCACTGCTCCCATTGGCTTGGCAATTGGCCCGGCTTTAGGGGGTTATCTA
CAAGCTTCAATTGGTTATCCAATTTTATTTTTAATAGCATCCGAATTGGCTTTTGTGGGGTTATTGGGAACGATTCAAGT
TTCTAATCCACCTGTACCACAAGGTCGCCAAGCAACAGAAAAGGATAGTAATTTCTGGCAACTTTTAAGTAGCCCACGGG
TGAGAGTGCCAACTTTGGTGATGTTGCTCATTGGTATAGCTATCGGTGCTGTGCATATTTTTTTACCACTGTTTATTAAA
TCAACAGGGGTGGAATTTAACGCCGGACTATTTTTTACGATCGCGGCCATTGGTAGTTTCAGTTTACGGGTATTTGCAGG
GAAAGCTAGCGATCGCTTCGGTCGGGGTTTGTTTATTACTTTCGGTATCATGGCTTATATGTTGTCATCTTTCTTGTTAT
GGCAAGCCAACAGTGCCATTAGTTTCGCTATTGCAGCGATCGCTGAAGGTTGTGGCGGCGGAACAATGATTTCGATGATT
ACGACGATGATGGCAGACCGCTCGCTACCACAAGAGCGAGGACGAATTTTCTCTATTTGTATCGCTGGATTGGATTTAGG
AATTGCGATCGCTGCCCCTATTTTAGGTTTTATTGCTGAAGCGACTGGCTATCGCAGTATGTTTGCCTATACAACTGCTT
TAACTTTCCTAGCCTTACTAATTTTCCTGACCAGATCGAGTAAAAATTTGAGCAATTCCCTGCGGTTTGCTCTGGGTCGC
GGTCAAGATGTCTATTCTCTGCATAATAGTAACTAG

Upstream 100 bases:

>100_bases
GTAGCAAAAAATGGCAACTAAGGTAAAAATATTAATCAAGAAGAAATCAGAATTCTGATTTTTTTGTTAACAAAACATTT
AGCATTAAATTGCATCTGCC

Downstream 100 bases:

>100_bases
TCAGGCAAAAATAAAAGCAGAGAAAATGTTTCTCTGCTTTTATCTCTAAAACGGGCGAGGAGGGATTCGAACCCCCGACA
CCGTGGTCCGTAGCCACGTG

Product: general substrate transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MKAFNTFDASLRLNLLILFTAGLLFWSSTATFLPTLPLYIEDVGGSKQEIGIVMGGFAIGLLVFRPMLGRMADQNGRKLL
LLIGTIVATIAPFGYLAFKSIPLLMLVRVFHGISIAAFTTGYSALIADLAPIAIRGEIISYMSLTAPIGLAIGPALGGYL
QASIGYPILFLIASELAFVGLLGTIQVSNPPVPQGRQATEKDSNFWQLLSSPRVRVPTLVMLLIGIAIGAVHIFLPLFIK
STGVEFNAGLFFTIAAIGSFSLRVFAGKASDRFGRGLFITFGIMAYMLSSFLLWQANSAISFAIAAIAEGCGGGTMISMI
TTMMADRSLPQERGRIFSICIAGLDLGIAIAAPILGFIAEATGYRSMFAYTTALTFLALLIFLTRSSKNLSNSLRFALGR
GQDVYSLHNSN

Sequences:

>Translated_411_residues
MKAFNTFDASLRLNLLILFTAGLLFWSSTATFLPTLPLYIEDVGGSKQEIGIVMGGFAIGLLVFRPMLGRMADQNGRKLL
LLIGTIVATIAPFGYLAFKSIPLLMLVRVFHGISIAAFTTGYSALIADLAPIAIRGEIISYMSLTAPIGLAIGPALGGYL
QASIGYPILFLIASELAFVGLLGTIQVSNPPVPQGRQATEKDSNFWQLLSSPRVRVPTLVMLLIGIAIGAVHIFLPLFIK
STGVEFNAGLFFTIAAIGSFSLRVFAGKASDRFGRGLFITFGIMAYMLSSFLLWQANSAISFAIAAIAEGCGGGTMISMI
TTMMADRSLPQERGRIFSICIAGLDLGIAIAAPILGFIAEATGYRSMFAYTTALTFLALLIFLTRSSKNLSNSLRFALGR
GQDVYSLHNSN
>Mature_411_residues
MKAFNTFDASLRLNLLILFTAGLLFWSSTATFLPTLPLYIEDVGGSKQEIGIVMGGFAIGLLVFRPMLGRMADQNGRKLL
LLIGTIVATIAPFGYLAFKSIPLLMLVRVFHGISIAAFTTGYSALIADLAPIAIRGEIISYMSLTAPIGLAIGPALGGYL
QASIGYPILFLIASELAFVGLLGTIQVSNPPVPQGRQATEKDSNFWQLLSSPRVRVPTLVMLLIGIAIGAVHIFLPLFIK
STGVEFNAGLFFTIAAIGSFSLRVFAGKASDRFGRGLFITFGIMAYMLSSFLLWQANSAISFAIAAIAEGCGGGTMISMI
TTMMADRSLPQERGRIFSICIAGLDLGIAIAAPILGFIAEATGYRSMFAYTTALTFLALLIFLTRSSKNLSNSLRFALGR
GQDVYSLHNSN

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787291, Length=380, Percent_Identity=22.8947368421053, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1788509, Length=287, Percent_Identity=27.8745644599303, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43917; Mature: 43917

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAFNTFDASLRLNLLILFTAGLLFWSSTATFLPTLPLYIEDVGGSKQEIGIVMGGFAIG
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCEEECCCCCCHHHHEEEHHHHHH
LLVFRPMLGRMADQNGRKLLLLIGTIVATIAPFGYLAFKSIPLLMLVRVFHGISIAAFTT
HHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHH
GYSALIADLAPIAIRGEIISYMSLTAPIGLAIGPALGGYLQASIGYPILFLIASELAFVG
HHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LLGTIQVSNPPVPQGRQATEKDSNFWQLLSSPRVRVPTLVMLLIGIAIGAVHIFLPLFIK
HHEEEEECCCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
STGVEFNAGLFFTIAAIGSFSLRVFAGKASDRFGRGLFITFGIMAYMLSSFLLWQANSAI
HCCCEECCCHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHH
SFAIAAIAEGCGGGTMISMITTMMADRSLPQERGRIFSICIAGLDLGIAIAAPILGFIAE
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHCCEEEHHHHHHHHHHHHHHHHHHHHHH
ATGYRSMFAYTTALTFLALLIFLTRSSKNLSNSLRFALGRGQDVYSLHNSN
HCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEECCCCC
>Mature Secondary Structure
MKAFNTFDASLRLNLLILFTAGLLFWSSTATFLPTLPLYIEDVGGSKQEIGIVMGGFAIG
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCEEECCCCCCHHHHEEEHHHHHH
LLVFRPMLGRMADQNGRKLLLLIGTIVATIAPFGYLAFKSIPLLMLVRVFHGISIAAFTT
HHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHH
GYSALIADLAPIAIRGEIISYMSLTAPIGLAIGPALGGYLQASIGYPILFLIASELAFVG
HHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LLGTIQVSNPPVPQGRQATEKDSNFWQLLSSPRVRVPTLVMLLIGIAIGAVHIFLPLFIK
HHEEEEECCCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
STGVEFNAGLFFTIAAIGSFSLRVFAGKASDRFGRGLFITFGIMAYMLSSFLLWQANSAI
HCCCEECCCHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHH
SFAIAAIAEGCGGGTMISMITTMMADRSLPQERGRIFSICIAGLDLGIAIAAPILGFIAE
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHCCEEEHHHHHHHHHHHHHHHHHHHHHH
ATGYRSMFAYTTALTFLALLIFLTRSSKNLSNSLRFALGRGQDVYSLHNSN
HCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]