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The map label for this gene is moaC

Identifier: 75909605

GI number: 75909605

Start: 4227406

End: 4227912

Strand: Direct

Name: moaC

Synonym: Ava_3399

Alternate gene names: 75909605

Gene position: 4227406-4227912 (Clockwise)

Preceding gene: 75909604

Following gene: 75909607

Centisome position: 66.41

GC content: 43.39

Gene sequence:

>507_bases
ATGCAAGACCCTTTTCCCAAAAATTCTGCAAATCTGACTCATCTCGATGGCCAGGGACAAGCACAGATGGTAGATGTGTC
TGATAAAGTACAAACGATTCGGCAAGCAGTGGCTGAGGCTCAAGTGCGGATGCTACCAGCGACTTTAGCCGCCATCCAAG
CTGGTAACACACCTAAAGGTGATGTTTTAGCCACTGCTAGACTAGCCGGGATTATGGCTGCTAAACAAACAGCAAATTTG
ATTCCCCTGTGTCATCCTTTGCCATTACAAAAAGTTGCGGTCGAGATTACGCCAGACCCCCAACTTCCTGGTTATCAAAT
ACGAGCCACAGTCAAAACTAAAGCCGAAACTGGTGTGGAAATGGAAGCTTTAACTGCCGTTTCTATTGCTGCTTTAACTT
TGTATGATATGGCAAAAGCTCTAGAAAAATCGATGCAAATTGAATCAATTAGATTAGTTAGTAAAACTGGTGGAAAATCA
GGAGATTATTTTCCACCAGCACCATAA

Upstream 100 bases:

>100_bases
GGATTCGAACCCCCGACACCGTGGTCCGTAGCCACGTGCTCTAGTCCACTGAGCTACACGCCCTTACAAGAAATATATAC
TAGCACCCTTTTTCATAATT

Downstream 100 bases:

>100_bases
TTTAATCTATTTCACCTATAGCTTTGTTTACATCTGTGGGATTTTCATATTCCTCATCTTCTGGTAATTGATCTAACAGG
GAAATTATTTTTTGATCGGC

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 168; Mature: 168

Protein sequence:

>168_residues
MQDPFPKNSANLTHLDGQGQAQMVDVSDKVQTIRQAVAEAQVRMLPATLAAIQAGNTPKGDVLATARLAGIMAAKQTANL
IPLCHPLPLQKVAVEITPDPQLPGYQIRATVKTKAETGVEMEALTAVSIAALTLYDMAKALEKSMQIESIRLVSKTGGKS
GDYFPPAP

Sequences:

>Translated_168_residues
MQDPFPKNSANLTHLDGQGQAQMVDVSDKVQTIRQAVAEAQVRMLPATLAAIQAGNTPKGDVLATARLAGIMAAKQTANL
IPLCHPLPLQKVAVEITPDPQLPGYQIRATVKTKAETGVEMEALTAVSIAALTLYDMAKALEKSMQIESIRLVSKTGGKS
GDYFPPAP
>Mature_168_residues
MQDPFPKNSANLTHLDGQGQAQMVDVSDKVQTIRQAVAEAQVRMLPATLAAIQAGNTPKGDVLATARLAGIMAAKQTANL
IPLCHPLPLQKVAVEITPDPQLPGYQIRATVKTKAETGVEMEALTAVSIAALTLYDMAKALEKSMQIESIRLVSKTGGKS
GDYFPPAP

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=154, Percent_Identity=55.1948051948052, Blast_Score=169, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=44.9664429530201, Blast_Score=127, Evalue=3e-30,
Organism=Drosophila melanogaster, GI28574490, Length=153, Percent_Identity=51.6339869281046, Blast_Score=147, Evalue=3e-36,
Organism=Drosophila melanogaster, GI28574492, Length=146, Percent_Identity=48.6301369863014, Blast_Score=124, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC_ANAVT (Q3M7N0)

Other databases:

- EMBL:   CP000117
- RefSeq:   YP_323901.1
- ProteinModelPortal:   Q3M7N0
- SMR:   Q3M7N0
- STRING:   Q3M7N0
- GeneID:   3680061
- GenomeReviews:   CP000117_GR
- KEGG:   ava:Ava_3399
- NMPDR:   fig|240292.3.peg.3949
- eggNOG:   COG0315
- HOGENOM:   HBG605231
- OMA:   PMCHPLM
- PhylomeDB:   Q3M7N0
- ProtClustDB:   PRK09364
- BioCyc:   AVAR240292:AVA_3399-MONOMER
- HAMAP:   MF_01224_B
- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 17788; Mature: 17788

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: ACT_SITE 136-136

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDPFPKNSANLTHLDGQGQAQMVDVSDKVQTIRQAVAEAQVRMLPATLAAIQAGNTPKG
CCCCCCCCCCCEEEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DVLATARLAGIMAAKQTANLIPLCHPLPLQKVAVEITPDPQLPGYQIRATVKTKAETGVE
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEEEECCCCCCC
MEALTAVSIAALTLYDMAKALEKSMQIESIRLVSKTGGKSGDYFPPAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHCCCCCCCCCCCCC
>Mature Secondary Structure
MQDPFPKNSANLTHLDGQGQAQMVDVSDKVQTIRQAVAEAQVRMLPATLAAIQAGNTPKG
CCCCCCCCCCCEEEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DVLATARLAGIMAAKQTANLIPLCHPLPLQKVAVEITPDPQLPGYQIRATVKTKAETGVE
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEEEECCCCCCC
MEALTAVSIAALTLYDMAKALEKSMQIESIRLVSKTGGKSGDYFPPAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA