Click here to switch to the map view.

The map label for this gene is cysH [H]

Identifier: 75909536

GI number: 75909536

Start: 4148853

End: 4149578

Strand: Direct

Name: cysH [H]

Synonym: Ava_3330

Alternate gene names: 75909536

Gene position: 4148853-4149578 (Clockwise)

Preceding gene: 75909534

Following gene: 75909537

Centisome position: 65.17

GC content: 42.84

Gene sequence:

>726_bases
ATGACAGCTTCTACGGCATTTAAAACCCAAACAAACGAATTTAATTTAGATGAATTAAATCAACAGTTTGAAACTGCCAC
TCCTAAAGAAATTCTGGCATGGTCTATAGAGCATATCCCCACAGGGTTGGTACAAACTAGCGCCTTTAATGTGGATGACT
TAGTAATTACCCATATCCTTTATAGTGAACTCAAGCAACCAGTACCTGTAATCTTTCTCGATACTCTGTTCCACTTTCAA
CAAACTCTAGAACTCGTTGCAAAAGCGAAAGAAATATACAACCTAGATTTACAAACCTACAAAACTCCAGATGTAGACAC
CCGCGAAGCCTTTACTGCTAAATATGGCGAGGCGCTTTGGGATAAAGATATTACACAATTTCACCAAGTTACCAAAATTG
AACCTCTACAACGGGGTTTAGATGAACTCAACACAGTTGCGTGGATTACTGGTCGTCGCCGTGATCAAGCAGTTACCCGC
GCTAATATGCCTGTATTTGAATTAGATGGCAAAGGTCGTTTGAAAGTAAATCCCCTAGCTACTTGGACACGTCAAGATAG
TTGGGCTTACGTAGCCGAACATGGTGTGATTTACAACCCACTCCACGACCAAGGTTATCCCAGCATTGGCGATGAACCCA
TCACCACCAAAGTGGGCGAAGGCGAAGACGAACGCGCCGGACGCTGGAGAGGAAGCAATAAAACTGAATGTGGGATTCAC
ATTTAG

Upstream 100 bases:

>100_bases
CAATATAATTACTTATATTCCCTCATATCCGAGCGAGTTGTGTGCCTTTTTGGTCTAAAATTAAGTTTAATCAAGGTAAC
AACATTTAACGGAAACTCTC

Downstream 100 bases:

>100_bases
TCAGTGGTCAGTAGTCCACAGTCCATAGTTCAACACAAAGATGTTAACTATTTAACAGTCAATGGTTCAACGCTGAAAAC
AACCATTAATATTGACTATT

Product: phosphoadenylylsulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MTASTAFKTQTNEFNLDELNQQFETATPKEILAWSIEHIPTGLVQTSAFNVDDLVITHILYSELKQPVPVIFLDTLFHFQ
QTLELVAKAKEIYNLDLQTYKTPDVDTREAFTAKYGEALWDKDITQFHQVTKIEPLQRGLDELNTVAWITGRRRDQAVTR
ANMPVFELDGKGRLKVNPLATWTRQDSWAYVAEHGVIYNPLHDQGYPSIGDEPITTKVGEGEDERAGRWRGSNKTECGIH
I

Sequences:

>Translated_241_residues
MTASTAFKTQTNEFNLDELNQQFETATPKEILAWSIEHIPTGLVQTSAFNVDDLVITHILYSELKQPVPVIFLDTLFHFQ
QTLELVAKAKEIYNLDLQTYKTPDVDTREAFTAKYGEALWDKDITQFHQVTKIEPLQRGLDELNTVAWITGRRRDQAVTR
ANMPVFELDGKGRLKVNPLATWTRQDSWAYVAEHGVIYNPLHDQGYPSIGDEPITTKVGEGEDERAGRWRGSNKTECGIH
I
>Mature_240_residues
TASTAFKTQTNEFNLDELNQQFETATPKEILAWSIEHIPTGLVQTSAFNVDDLVITHILYSELKQPVPVIFLDTLFHFQQ
TLELVAKAKEIYNLDLQTYKTPDVDTREAFTAKYGEALWDKDITQFHQVTKIEPLQRGLDELNTVAWITGRRRDQAVTRA
NMPVFELDGKGRLKVNPLATWTRQDSWAYVAEHGVIYNPLHDQGYPSIGDEPITTKVGEGEDERAGRWRGSNKTECGIHI

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=228, Percent_Identity=32.4561403508772, Blast_Score=131, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6325425, Length=233, Percent_Identity=42.9184549356223, Blast_Score=172, Evalue=5e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011798
- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 27462; Mature: 27331

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASTAFKTQTNEFNLDELNQQFETATPKEILAWSIEHIPTGLVQTSAFNVDDLVITHIL
CCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHH
YSELKQPVPVIFLDTLFHFQQTLELVAKAKEIYNLDLQTYKTPDVDTREAFTAKYGEALW
HHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHH
DKDITQFHQVTKIEPLQRGLDELNTVAWITGRRRDQAVTRANMPVFELDGKGRLKVNPLA
HHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHCCCCEEEECCCCCEEECCCE
TWTRQDSWAYVAEHGVIYNPLHDQGYPSIGDEPITTKVGEGEDERAGRWRGSNKTECGIH
EECCCCCEEEEECCCEEECCCCCCCCCCCCCCCCEECCCCCCCHHCCCCCCCCCCCCCCC
I
C
>Mature Secondary Structure 
TASTAFKTQTNEFNLDELNQQFETATPKEILAWSIEHIPTGLVQTSAFNVDDLVITHIL
CCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHH
YSELKQPVPVIFLDTLFHFQQTLELVAKAKEIYNLDLQTYKTPDVDTREAFTAKYGEALW
HHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHH
DKDITQFHQVTKIEPLQRGLDELNTVAWITGRRRDQAVTRANMPVFELDGKGRLKVNPLA
HHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHCCCCEEEECCCCCEEECCCE
TWTRQDSWAYVAEHGVIYNPLHDQGYPSIGDEPITTKVGEGEDERAGRWRGSNKTECGIH
EECCCCCEEEEECCCEEECCCCCCCCCCCCCCCCEECCCCCCCHHCCCCCCCCCCCCCCC
I
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]