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The map label for this gene is 75909400

Identifier: 75909400

GI number: 75909400

Start: 3967627

End: 3968766

Strand: Direct

Name: 75909400

Synonym: Ava_3193

Alternate gene names: NA

Gene position: 3967627-3968766 (Clockwise)

Preceding gene: 75909399

Following gene: 75909401

Centisome position: 62.33

GC content: 46.14

Gene sequence:

>1140_bases
GTGGTCTTATTGAAAGGCTTTGAAATTGAAATGTACACCGGTACCCCTCAAGGTGAAATCGTCGGTCTCTCGGATAAAAT
TGTGACTCAATTAGACGGGTTTGTACGAGAACCAGATAGCCGGAACGTAGAATACACGACAGAACCACTGCACAGTTATG
AAAGTTTGCTGTGTGCTTTGTTGCGTCCTCGACAGGCATTAAGAGACTACCTCAAGCAATTAGGTGACTATACCCTCATT
CCTGGCAGCACATTATCTTTGGGTGGAAGCGATCGCTTTTTCCGATCTGACCCAGCCAACCCATATCATGACTATATTGA
GCAAACCTACGGGACAAAAGTAGTTACCGCTAGCGTTCATATAAACGTAGGTATTGACGATCCAGAAGTGTTAATGCGGG
CTTGTCGGTTAATTCGCGTCGAAGCACCCCTATTTTTAGCCCTAAGCGCCTCATCTCCCTTCATCGATGGTAAAGCTACT
GGTTATCATTCCACCCGTTGGGGAGTCTTCCCCCAAACGCCAACTAACGTCCCACTATTTACCAGCCACGCCCATCATAT
AGAGTGGGTAGAACAGCAATTGGCTATCGGGACAATGCAGAACGTCCGCCACCTCTGGGTATCAGTCAGACCAAATGGTG
ATCGCCGTCCCTATGATTTAAACCGTTTAGAATTAAGAATCTGTGATTTAGTTACAGATCCAATCTCCTTATTGGCGATT
ACAGCCTTACTAGAAGCGCGGTTATTACAACTAATAGAAAATCCCGACCTAGATCCCTTAACCCAAAGTAAGTTTTCCCC
CGAAGAACTCGTAACCCTCACTACTGAAAACGAAGCCGCAGCCGCTAGCGCTAGTCTCGATGCCCAACTGACACATTGGC
AAGACGGTAGAAGCATCATAGCTAGAGATTGGGTGAATGAAATATATCAAGAAGTTTGGGCGATCGCTAAAAAACATGGC
TTTAGCTGTTTCCTCTCCCCTCTCCAGAAAATTTTACGTGAAGGTAACGAAGCCCAACACTGGCTACAGCTGCATAAAGT
CGGCTTCGACACCCAATGCGTTATCACCCAAGCAATCAGTACCACCCAGGAACGGGAACTTGAACTGCAAAATAAGTTGT
GTACACAGCTAAAGGGGTAA

Upstream 100 bases:

>100_bases
ACGGTTCCATAATTCTTAACTTTAAATTTGCCCGAATGTCGATGTAAAGGATTGTCTAACTCGATACAATTTAAAGGCTG
GGAGAGCCGAGGAGAATAAA

Downstream 100 bases:

>100_bases
GTTAATAGTCAATAGTCAATGGTCAATAGTCAATAGTCAATAGTTCAGAGTAAAAACAACCAACAACTGACAACTGACAA
CCGACTATTGACCAAATTTT

Product: glutamate--cysteine ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MVLLKGFEIEMYTGTPQGEIVGLSDKIVTQLDGFVREPDSRNVEYTTEPLHSYESLLCALLRPRQALRDYLKQLGDYTLI
PGSTLSLGGSDRFFRSDPANPYHDYIEQTYGTKVVTASVHINVGIDDPEVLMRACRLIRVEAPLFLALSASSPFIDGKAT
GYHSTRWGVFPQTPTNVPLFTSHAHHIEWVEQQLAIGTMQNVRHLWVSVRPNGDRRPYDLNRLELRICDLVTDPISLLAI
TALLEARLLQLIENPDLDPLTQSKFSPEELVTLTTENEAAAASASLDAQLTHWQDGRSIIARDWVNEIYQEVWAIAKKHG
FSCFLSPLQKILREGNEAQHWLQLHKVGFDTQCVITQAISTTQERELELQNKLCTQLKG

Sequences:

>Translated_379_residues
MVLLKGFEIEMYTGTPQGEIVGLSDKIVTQLDGFVREPDSRNVEYTTEPLHSYESLLCALLRPRQALRDYLKQLGDYTLI
PGSTLSLGGSDRFFRSDPANPYHDYIEQTYGTKVVTASVHINVGIDDPEVLMRACRLIRVEAPLFLALSASSPFIDGKAT
GYHSTRWGVFPQTPTNVPLFTSHAHHIEWVEQQLAIGTMQNVRHLWVSVRPNGDRRPYDLNRLELRICDLVTDPISLLAI
TALLEARLLQLIENPDLDPLTQSKFSPEELVTLTTENEAAAASASLDAQLTHWQDGRSIIARDWVNEIYQEVWAIAKKHG
FSCFLSPLQKILREGNEAQHWLQLHKVGFDTQCVITQAISTTQERELELQNKLCTQLKG
>Mature_379_residues
MVLLKGFEIEMYTGTPQGEIVGLSDKIVTQLDGFVREPDSRNVEYTTEPLHSYESLLCALLRPRQALRDYLKQLGDYTLI
PGSTLSLGGSDRFFRSDPANPYHDYIEQTYGTKVVTASVHINVGIDDPEVLMRACRLIRVEAPLFLALSASSPFIDGKAT
GYHSTRWGVFPQTPTNVPLFTSHAHHIEWVEQQLAIGTMQNVRHLWVSVRPNGDRRPYDLNRLELRICDLVTDPISLLAI
TALLEARLLQLIENPDLDPLTQSKFSPEELVTLTTENEAAAASASLDAQLTHWQDGRSIIARDWVNEIYQEVWAIAKKHG
FSCFLSPLQKILREGNEAQHWLQLHKVGFDTQCVITQAISTTQERELELQNKLCTQLKG

Specific function: ATP-dependent carboxylate-amine ligase [H]

COG id: COG2170

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carboxylate-amine ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011793
- InterPro:   IPR006336 [H]

Pfam domain/function: PF04107 GCS2 [H]

EC number: NA

Molecular weight: Translated: 42761; Mature: 42761

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLLKGFEIEMYTGTPQGEIVGLSDKIVTQLDGFVREPDSRNVEYTTEPLHSYESLLCAL
CEEEEEEEEEEEECCCCCCEEECHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHH
LRPRQALRDYLKQLGDYTLIPGSTLSLGGSDRFFRSDPANPYHDYIEQTYGTKVVTASVH
HCHHHHHHHHHHHHCCEEECCCCEEECCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEEE
INVGIDDPEVLMRACRLIRVEAPLFLALSASSPFIDGKATGYHSTRWGVFPQTPTNVPLF
EEECCCCHHHHHHHHHHHEECCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
TSHAHHIEWVEQQLAIGTMQNVRHLWVSVRPNGDRRPYDLNRLELRICDLVTDPISLLAI
CCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCHHHEEHHHHHHCHHHHHHH
TALLEARLLQLIENPDLDPLTQSKFSPEELVTLTTENEAAAASASLDAQLTHWQDGRSII
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHCCCCCEEEECCCCCHHH
ARDWVNEIYQEVWAIAKKHGFSCFLSPLQKILREGNEAQHWLQLHKVGFDTQCVITQAIS
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHH
TTQERELELQNKLCTQLKG
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVLLKGFEIEMYTGTPQGEIVGLSDKIVTQLDGFVREPDSRNVEYTTEPLHSYESLLCAL
CEEEEEEEEEEEECCCCCCEEECHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHH
LRPRQALRDYLKQLGDYTLIPGSTLSLGGSDRFFRSDPANPYHDYIEQTYGTKVVTASVH
HCHHHHHHHHHHHHCCEEECCCCEEECCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEEE
INVGIDDPEVLMRACRLIRVEAPLFLALSASSPFIDGKATGYHSTRWGVFPQTPTNVPLF
EEECCCCHHHHHHHHHHHEECCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
TSHAHHIEWVEQQLAIGTMQNVRHLWVSVRPNGDRRPYDLNRLELRICDLVTDPISLLAI
CCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCHHHEEHHHHHHCHHHHHHH
TALLEARLLQLIENPDLDPLTQSKFSPEELVTLTTENEAAAASASLDAQLTHWQDGRSII
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHCCCCCEEEECCCCCHHH
ARDWVNEIYQEVWAIAKKHGFSCFLSPLQKILREGNEAQHWLQLHKVGFDTQCVITQAIS
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHH
TTQERELELQNKLCTQLKG
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA