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The map label for this gene is argJ [H]

Identifier: 75909325

GI number: 75909325

Start: 3873185

End: 3874426

Strand: Direct

Name: argJ [H]

Synonym: Ava_3118

Alternate gene names: 75909325

Gene position: 3873185-3874426 (Clockwise)

Preceding gene: 75909323

Following gene: 75909326

Centisome position: 60.84

GC content: 47.58

Gene sequence:

>1242_bases
ATGGCAGACTGGCAGGAAATTACTGGTGGAATTACAGCACCAAAAGGTTATCGGGCGGCGGGAATTACAGCAGGACTCAA
ACCTTCGGGGTTGCCAGATTTAGCTTTGATAGTATCAGACGTAGAAGCGATCGCAGCTGGTGTATTCACAACCAGTCAAG
TAAAAGCTGCTTGTGTAGACTACTGTCGCCAACGTTTACAAGCCAAGCAAAGCGCCCGCGCCATCCTCTGCAATGCTGGA
CAAGCCAACGCCGCTACAGGTAGTCAAGGTATTAAGGATGCAGAAGAAAGCGCCGATTTGTTAGCAAAAGAGTTAAATAT
TTCCCCCGAATCAATTCTGTTGGCTTCCACTGGGGTAATTGGTCAACGAATTAAAATGGATGCCTTACGCAACGGTATTC
CTAAACTTGTAGCATCCCTTACTGATGCAGGCTCAGATGCAGCCGCCGGGGCAATTATCACTACAGATTTGGTCACAAAA
TCTATTGCCTTAGAAACCACTATAGGAGATCGCCCAGTCCGCATTGGTGGTATCGCCAAAGGTTCAGGGATGATTCATCC
CAACATGGCGACAATGTTGGCTTTTGTTACCTGTGATGCCGCAGTTTCCCCTCATCTTTGGCAACAGATGTTAACTAGGG
CAGCCGATAGAAGCTTCAATTCCATTACAGTAGATGGAGATACCAGCACCAATGATAGTTTAATTGCCCTAGCCAATGGA
CAATCTCGCACCCCAGCAATTACTGAAGTAGGTGCAGAATCAGAAAAATTAGAGGCCATGCTAACAGCAGTATGCCAGCA
TTTAGCCAAGGCGATCACTCGTGATGGTGAAGGTGCAACTTGTCTTATAGAAGTGCAAGTTACAGGCGCGCATGATGAAC
AAGCAGCTAGACAAATCGCCAAAACTATTGCTGGTTCATCATTAGTGAAGTCTGCAATCTTCGGTCGTGACCCAAATTGG
GGGCGCATCGCCGCCGCCGCCGGACGCGCAGGTGTTCCCTTCGAGCAGGAAAACCTGCAAATTCAGCTAGGAGATTTTTT
ACTCTTAGACAATGGTCAACCCCTCCCCTTTGACCGCGCCGCCGCCAGTGCGTATTTAAAACAAGCTGCTACAGGTGCTT
ATCTTCAACAAGATACCGTCTTAATTTCCGTCAATGTGGGTAATGGTCACGGCACTGGCAAAGCTTGGGGATGCGATTTA
AGTTACGACTACGTGAAGATTAATGCTGAGTATACAACTTAG

Upstream 100 bases:

>100_bases
AGAATTACAAATTAGGAATTACGAATTACAAATTACAAATTGCGAATTGATATAATCGCCAGTCAAGCCACTAAGTTTAG
TTGTAAGGGTAAAAATAAAG

Downstream 100 bases:

>100_bases
GGTTGGGGAGAAAAAAGTCATACCAATTTGAAAACAGAATGCGACAAATAAACCATCTGTAGAGACGCGATTAATCGCGT
CTTCACCCAATGATGTATTG

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS [H]

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MADWQEITGGITAPKGYRAAGITAGLKPSGLPDLALIVSDVEAIAAGVFTTSQVKAACVDYCRQRLQAKQSARAILCNAG
QANAATGSQGIKDAEESADLLAKELNISPESILLASTGVIGQRIKMDALRNGIPKLVASLTDAGSDAAAGAIITTDLVTK
SIALETTIGDRPVRIGGIAKGSGMIHPNMATMLAFVTCDAAVSPHLWQQMLTRAADRSFNSITVDGDTSTNDSLIALANG
QSRTPAITEVGAESEKLEAMLTAVCQHLAKAITRDGEGATCLIEVQVTGAHDEQAARQIAKTIAGSSLVKSAIFGRDPNW
GRIAAAAGRAGVPFEQENLQIQLGDFLLLDNGQPLPFDRAAASAYLKQAATGAYLQQDTVLISVNVGNGHGTGKAWGCDL
SYDYVKINAEYTT

Sequences:

>Translated_413_residues
MADWQEITGGITAPKGYRAAGITAGLKPSGLPDLALIVSDVEAIAAGVFTTSQVKAACVDYCRQRLQAKQSARAILCNAG
QANAATGSQGIKDAEESADLLAKELNISPESILLASTGVIGQRIKMDALRNGIPKLVASLTDAGSDAAAGAIITTDLVTK
SIALETTIGDRPVRIGGIAKGSGMIHPNMATMLAFVTCDAAVSPHLWQQMLTRAADRSFNSITVDGDTSTNDSLIALANG
QSRTPAITEVGAESEKLEAMLTAVCQHLAKAITRDGEGATCLIEVQVTGAHDEQAARQIAKTIAGSSLVKSAIFGRDPNW
GRIAAAAGRAGVPFEQENLQIQLGDFLLLDNGQPLPFDRAAASAYLKQAATGAYLQQDTVLISVNVGNGHGTGKAWGCDL
SYDYVKINAEYTT
>Mature_412_residues
ADWQEITGGITAPKGYRAAGITAGLKPSGLPDLALIVSDVEAIAAGVFTTSQVKAACVDYCRQRLQAKQSARAILCNAGQ
ANAATGSQGIKDAEESADLLAKELNISPESILLASTGVIGQRIKMDALRNGIPKLVASLTDAGSDAAAGAIITTDLVTKS
IALETTIGDRPVRIGGIAKGSGMIHPNMATMLAFVTCDAAVSPHLWQQMLTRAADRSFNSITVDGDTSTNDSLIALANGQ
SRTPAITEVGAESEKLEAMLTAVCQHLAKAITRDGEGATCLIEVQVTGAHDEQAARQIAKTIAGSSLVKSAIFGRDPNWG
RIAAAAGRAGVPFEQENLQIQLGDFLLLDNGQPLPFDRAAASAYLKQAATGAYLQQDTVLISVNVGNGHGTGKAWGCDLS
YDYVKINAEYTT

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate [H]

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=417, Percent_Identity=37.1702637889688, Blast_Score=240, Evalue=3e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002813
- InterPro:   IPR016117 [H]

Pfam domain/function: PF01960 ArgJ [H]

EC number: =2.3.1.35; =2.3.1.1 [H]

Molecular weight: Translated: 42924; Mature: 42793

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADWQEITGGITAPKGYRAAGITAGLKPSGLPDLALIVSDVEAIAAGVFTTSQVKAACVD
CCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YCRQRLQAKQSARAILCNAGQANAATGSQGIKDAEESADLLAKELNISPESILLASTGVI
HHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHEEEEECCCH
GQRIKMDALRNGIPKLVASLTDAGSDAAAGAIITTDLVTKSIALETTIGDRPVRIGGIAK
HHHHHHHHHHCCHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHEEEECCCCCCEEEEEEEC
GSGMIHPNMATMLAFVTCDAAVSPHLWQQMLTRAADRSFNSITVDGDTSTNDSLIALANG
CCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEECC
QSRTPAITEVGAESEKLEAMLTAVCQHLAKAITRDGEGATCLIEVQVTGAHDEQAARQIA
CCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCHHHHHHHHH
KTIAGSSLVKSAIFGRDPNWGRIAAAAGRAGVPFEQENLQIQLGDFLLLDNGQPLPFDRA
HHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCEEEECCEEEECCCCCCCHHHH
AASAYLKQAATGAYLQQDTVLISVNVGNGHGTGKAWGCDLSYDYVKINAEYTT
HHHHHHHHHHCCCEEECCEEEEEEECCCCCCCCCEEECCCCEEEEEEEEEECC
>Mature Secondary Structure 
ADWQEITGGITAPKGYRAAGITAGLKPSGLPDLALIVSDVEAIAAGVFTTSQVKAACVD
CCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YCRQRLQAKQSARAILCNAGQANAATGSQGIKDAEESADLLAKELNISPESILLASTGVI
HHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHEEEEECCCH
GQRIKMDALRNGIPKLVASLTDAGSDAAAGAIITTDLVTKSIALETTIGDRPVRIGGIAK
HHHHHHHHHHCCHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHEEEECCCCCCEEEEEEEC
GSGMIHPNMATMLAFVTCDAAVSPHLWQQMLTRAADRSFNSITVDGDTSTNDSLIALANG
CCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEECC
QSRTPAITEVGAESEKLEAMLTAVCQHLAKAITRDGEGATCLIEVQVTGAHDEQAARQIA
CCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCHHHHHHHHH
KTIAGSSLVKSAIFGRDPNWGRIAAAAGRAGVPFEQENLQIQLGDFLLLDNGQPLPFDRA
HHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCEEEECCEEEECCCCCCCHHHH
AASAYLKQAATGAYLQQDTVLISVNVGNGHGTGKAWGCDLSYDYVKINAEYTT
HHHHHHHHHHCCCEEECCEEEEEEECCCCCCCCCEEECCCCEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]