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The map label for this gene is cvrA [H]

Identifier: 75908952

GI number: 75908952

Start: 3379733

End: 3381622

Strand: Direct

Name: cvrA [H]

Synonym: Ava_2740

Alternate gene names: 75908952

Gene position: 3379733-3381622 (Clockwise)

Preceding gene: 75908949

Following gene: 75908955

Centisome position: 53.09

GC content: 45.98

Gene sequence:

>1890_bases
ATGGAAGCATCATTTGAAGTCACCCTACAAATGGCGATCGCTGTTTTTGCAGGCATCGGCGCTCAAGTCCTAGCGGCTTA
TTTGCGTGTACCCAGCATCGTCATATTGCTGTTGTTGGGCATTTTTCTAGGTGCTGATGGGGTTGGGTTACTACATCCCC
AATTACTCGGTACAGGGCTGGAAGTGATTGTTGCCCTAGCAACGGCAATCATCCTGTTTGAAGGTGGGTTGAATTTAGAT
TTACGCGAATTAGGTAGAGTTTCTATCAGCCTGCAAAGGCTGGTCACCTTAGGGACGCTAATCACCCTCATTGGGGGTAG
TATGGCCGCCCATTGGCTGGGTGAATTTCCTTGGAATATAGCTTTTCTCTACGCGTCTATTGTTGTGGTTACAGGGCCTA
CGGTCATCAGTCCTCTGCTCAAACAAATCAATGTAGACAGGCAAGTGGCGACGTTATTAGAAGGCGAGGGAGTTCTCATC
GACCCAGTGGGAGCTATTTTAGCTTTTGTGGTGTTGGACACCATCGTTAACGGTGATGCAGACCCAGTAAACGCCATTAT
CGGTTTACTCATGCGCTTGGGTATTGGTGCAGCCATCGGTGCGGCTGGTGGTTATTTCATGAGTTTGATTTTCAAACGCG
CCAATTTTCTTTCGTCTGAGTTAAAAAACCTAGTGGTTTTGGCGGTGCTATGGAGCTTATTTACTCTAGCGCAGATGATT
CGCAGTGAATCGGGTGTAATGACAACTGTCATCGCTGGGGCAGTATTCGCTAACTCTTCCGTACCAGAGGAACGTTCCTT
ACGCAGTTTCAAAGGTCAACTGACGATTTTGAGCGTTTCTGTCCTCTTCATTCTGTTAGCAGCTGATTTATCCATTGCCA
GCGTGTTTGCTTTGGGTTGGGGCAGCTTGTTTACTGTATTGGTCTTGATGTTTGTTGTTCGCCCTGTAAATATCTTGTTC
TGCACTTGGAACAGTAACTTAAACTGGCGACAGAAACTATTTTTAAGCTGGGTTGCGCCTAGAGGAATTGTCTCGGCATC
TGTTGCGTCCTTATTTGCGATTTTGCTCACTCAGCGCGGGGTCAATGGTGGTGATTCCATCAAAGCTTTAGTTTTCCTCA
CCATTATCATGACGGTGGTTTGTCAAGGATTAACAGCTGGTTGGGTGGCGACTTGTTTGGGCATCACTTCCCAAGAAGCT
ACAGGTGCAGTGATTGTTGGTTGTAATCCTTTGAGTCTGTTAATTGCCAGATTTTTCCAAGAACGGGGGGAAAATGTCGT
TTTGATTGATACTGACCCAGATTGTATTGCTCAAGCAGAAACGCAAAATCTGCGGGTGATTGCTAGCAGTGCGCTGGATG
GCGAGGTATTAGAAGAAGCTGGACTGGCATCGATGGGAACTTTTTTGGCGATGACTAGTAATGGTGAGGTAAACTTTGTT
TTAGCCGAAAGGGCAGCCGAGGAATTTAATCCGCCCCGCGTTTTGGCTGTTTTCCCCCGCGATCCTCAGGCGAACGGTTC
GACTAATAATAAAGTCCAACAAGCTTTTGTTTCTGATTTGCCGATTAAGATTTGGAACGAATATCTGAATGATGGACGGG
TGAAGTTAGGCACAACTACCCTGAGCGAATCGGAGTTTACTAGTCAACAAGAACATATTCAAGAAAAAATTCGGACTGGG
GTGTTAGTGCCGTTGTTAGTAGAAAGGGAAGAACGCCTACAAATTATCCCAGCAAACCAAGAATGGGAAGTAGGCGATCG
CATTATCTACCTATTACATGACCCCAGACCGAACCTATTAAAACGTTTATCCGGTGCTAGTCAATCCACACCTTTAGTCT
TAGAAACTTTACCAGAGGTGGAAGAAGTACCTTTAGCAAAGGCGCTTTAA

Upstream 100 bases:

>100_bases
AATTCATCGAGGTATAAACTGTCTGATGTTGTAACCTGTAAAGATGACATTTACTTTTCTTTACAAAGGATTTTGAAAGA
AATCGCTCAAAATCTAAAAC

Downstream 100 bases:

>100_bases
CTTTCAGCTAGCGACACTTGCTTGTTTCAGTTGCATAACTTCCTCCCTCGTTTCTGCGTACATTTGCCGTTCTTGCCACA
ATAAAGCTGACAAATGTACC

Product: sodium/hydrogen exchanger

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 629; Mature: 629

Protein sequence:

>629_residues
MEASFEVTLQMAIAVFAGIGAQVLAAYLRVPSIVILLLLGIFLGADGVGLLHPQLLGTGLEVIVALATAIILFEGGLNLD
LRELGRVSISLQRLVTLGTLITLIGGSMAAHWLGEFPWNIAFLYASIVVVTGPTVISPLLKQINVDRQVATLLEGEGVLI
DPVGAILAFVVLDTIVNGDADPVNAIIGLLMRLGIGAAIGAAGGYFMSLIFKRANFLSSELKNLVVLAVLWSLFTLAQMI
RSESGVMTTVIAGAVFANSSVPEERSLRSFKGQLTILSVSVLFILLAADLSIASVFALGWGSLFTVLVLMFVVRPVNILF
CTWNSNLNWRQKLFLSWVAPRGIVSASVASLFAILLTQRGVNGGDSIKALVFLTIIMTVVCQGLTAGWVATCLGITSQEA
TGAVIVGCNPLSLLIARFFQERGENVVLIDTDPDCIAQAETQNLRVIASSALDGEVLEEAGLASMGTFLAMTSNGEVNFV
LAERAAEEFNPPRVLAVFPRDPQANGSTNNKVQQAFVSDLPIKIWNEYLNDGRVKLGTTTLSESEFTSQQEHIQEKIRTG
VLVPLLVEREERLQIIPANQEWEVGDRIIYLLHDPRPNLLKRLSGASQSTPLVLETLPEVEEVPLAKAL

Sequences:

>Translated_629_residues
MEASFEVTLQMAIAVFAGIGAQVLAAYLRVPSIVILLLLGIFLGADGVGLLHPQLLGTGLEVIVALATAIILFEGGLNLD
LRELGRVSISLQRLVTLGTLITLIGGSMAAHWLGEFPWNIAFLYASIVVVTGPTVISPLLKQINVDRQVATLLEGEGVLI
DPVGAILAFVVLDTIVNGDADPVNAIIGLLMRLGIGAAIGAAGGYFMSLIFKRANFLSSELKNLVVLAVLWSLFTLAQMI
RSESGVMTTVIAGAVFANSSVPEERSLRSFKGQLTILSVSVLFILLAADLSIASVFALGWGSLFTVLVLMFVVRPVNILF
CTWNSNLNWRQKLFLSWVAPRGIVSASVASLFAILLTQRGVNGGDSIKALVFLTIIMTVVCQGLTAGWVATCLGITSQEA
TGAVIVGCNPLSLLIARFFQERGENVVLIDTDPDCIAQAETQNLRVIASSALDGEVLEEAGLASMGTFLAMTSNGEVNFV
LAERAAEEFNPPRVLAVFPRDPQANGSTNNKVQQAFVSDLPIKIWNEYLNDGRVKLGTTTLSESEFTSQQEHIQEKIRTG
VLVPLLVEREERLQIIPANQEWEVGDRIIYLLHDPRPNLLKRLSGASQSTPLVLETLPEVEEVPLAKAL
>Mature_629_residues
MEASFEVTLQMAIAVFAGIGAQVLAAYLRVPSIVILLLLGIFLGADGVGLLHPQLLGTGLEVIVALATAIILFEGGLNLD
LRELGRVSISLQRLVTLGTLITLIGGSMAAHWLGEFPWNIAFLYASIVVVTGPTVISPLLKQINVDRQVATLLEGEGVLI
DPVGAILAFVVLDTIVNGDADPVNAIIGLLMRLGIGAAIGAAGGYFMSLIFKRANFLSSELKNLVVLAVLWSLFTLAQMI
RSESGVMTTVIAGAVFANSSVPEERSLRSFKGQLTILSVSVLFILLAADLSIASVFALGWGSLFTVLVLMFVVRPVNILF
CTWNSNLNWRQKLFLSWVAPRGIVSASVASLFAILLTQRGVNGGDSIKALVFLTIIMTVVCQGLTAGWVATCLGITSQEA
TGAVIVGCNPLSLLIARFFQERGENVVLIDTDPDCIAQAETQNLRVIASSALDGEVLEEAGLASMGTFLAMTSNGEVNFV
LAERAAEEFNPPRVLAVFPRDPQANGSTNNKVQQAFVSDLPIKIWNEYLNDGRVKLGTTTLSESEFTSQQEHIQEKIRTG
VLVPLLVEREERLQIIPANQEWEVGDRIIYLLHDPRPNLLKRLSGASQSTPLVLETLPEVEEVPLAKAL

Specific function: Participates in control of cell volume in low-osmolarity conditions [H]

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK C-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018421
- InterPro:   IPR006153
- InterPro:   IPR018422
- InterPro:   IPR016169
- InterPro:   IPR006037
- InterPro:   IPR005170 [H]

Pfam domain/function: PF03471 CorC_HlyC; PF00999 Na_H_Exchanger; PF02080 TrkA_C [H]

EC number: NA

Molecular weight: Translated: 67516; Mature: 67516

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEASFEVTLQMAIAVFAGIGAQVLAAYLRVPSIVILLLLGIFLGADGVGLLHPQLLGTGL
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
EVIVALATAIILFEGGLNLDLRELGRVSISLQRLVTLGTLITLIGGSMAAHWLGEFPWNI
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHH
AFLYASIVVVTGPTVISPLLKQINVDRQVATLLEGEGVLIDPVGAILAFVVLDTIVNGDA
HHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHCCCCEEECCHHHHHHHHHHHHHHCCCC
DPVNAIIGLLMRLGIGAAIGAAGGYFMSLIFKRANFLSSELKNLVVLAVLWSLFTLAQMI
CHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSESGVMTTVIAGAVFANSSVPEERSLRSFKGQLTILSVSVLFILLAADLSIASVFALGW
HCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GSLFTVLVLMFVVRPVNILFCTWNSNLNWRQKLFLSWVAPRGIVSASVASLFAILLTQRG
HHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
VNGGDSIKALVFLTIIMTVVCQGLTAGWVATCLGITSQEATGAVIVGCNPLSLLIARFFQ
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHH
ERGENVVLIDTDPDCIAQAETQNLRVIASSALDGEVLEEAGLASMGTFLAMTSNGEVNFV
HHCCEEEEEECCCHHHHHCCCCCEEEEECCCCCHHHHHHCCCHHHCCEEEEECCCCEEEE
LAERAAEEFNPPRVLAVFPRDPQANGSTNNKVQQAFVSDLPIKIWNEYLNDGRVKLGTTT
EEHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCEEEEEEE
LSESEFTSQQEHIQEKIRTGVLVPLLVEREERLQIIPANQEWEVGDRIIYLLHDPRPNLL
CCCHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEECCCCCCCCCCEEEEEEECCCHHHH
KRLSGASQSTPLVLETLPEVEEVPLAKAL
HHHCCCCCCCCCHHHHCCCHHHCCCCCCC
>Mature Secondary Structure
MEASFEVTLQMAIAVFAGIGAQVLAAYLRVPSIVILLLLGIFLGADGVGLLHPQLLGTGL
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
EVIVALATAIILFEGGLNLDLRELGRVSISLQRLVTLGTLITLIGGSMAAHWLGEFPWNI
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHH
AFLYASIVVVTGPTVISPLLKQINVDRQVATLLEGEGVLIDPVGAILAFVVLDTIVNGDA
HHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHCCCCEEECCHHHHHHHHHHHHHHCCCC
DPVNAIIGLLMRLGIGAAIGAAGGYFMSLIFKRANFLSSELKNLVVLAVLWSLFTLAQMI
CHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSESGVMTTVIAGAVFANSSVPEERSLRSFKGQLTILSVSVLFILLAADLSIASVFALGW
HCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GSLFTVLVLMFVVRPVNILFCTWNSNLNWRQKLFLSWVAPRGIVSASVASLFAILLTQRG
HHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
VNGGDSIKALVFLTIIMTVVCQGLTAGWVATCLGITSQEATGAVIVGCNPLSLLIARFFQ
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHH
ERGENVVLIDTDPDCIAQAETQNLRVIASSALDGEVLEEAGLASMGTFLAMTSNGEVNFV
HHCCEEEEEECCCHHHHHCCCCCEEEEECCCCCHHHHHHCCCHHHCCEEEEECCCCEEEE
LAERAAEEFNPPRVLAVFPRDPQANGSTNNKVQQAFVSDLPIKIWNEYLNDGRVKLGTTT
EEHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCEEEEEEE
LSESEFTSQQEHIQEKIRTGVLVPLLVEREERLQIIPANQEWEVGDRIIYLLHDPRPNLL
CCCHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEECCCCCCCCCCEEEEEEECCCHHHH
KRLSGASQSTPLVLETLPEVEEVPLAKAL
HHHCCCCCCCCCHHHHCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA