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The map label for this gene is cph2 [H]

Identifier: 75908738

GI number: 75908738

Start: 3120786

End: 3123041

Strand: Direct

Name: cph2 [H]

Synonym: Ava_2524

Alternate gene names: 75908738

Gene position: 3120786-3123041 (Clockwise)

Preceding gene: 75908737

Following gene: 75908741

Centisome position: 49.02

GC content: 42.42

Gene sequence:

>2256_bases
ATGAATATCAACCCAGTAGATTCAGCCATCAAGTTGAAGCAGCAGTCGCATCCGCATATTCTTTTTGGGACAGAGGTAGA
TGAACACAGCAGTGGCGAACAATTATTACTGAGTATGTATGATTCTGTGCAGACATCTATATTTGTGGTGGATGTTCTAC
AAGATGGAGATTTTCAGTATGTAGCACTCAATCCCACCCATGAAAGATGGGTAGGGATTAGGTCAGAAGATTTGCGGGGC
AAAAAACCAGAAGATATTTTAACAGCTGTTGATGCGGCTAAAGTGCGTCAGCACTATGCTGACTGTGTACGCTTTGGCAA
AACGATTTCCTATGAACAATGCTTACAGTTTCAGGGAGTAAGCACTTGGTGGAGTACAACGCTTACGCCACTACGAGATA
CTAACTCCAAAATTTATCGATTGATTGGCACTAGTAGCAATATCACTGCGGCAAAACAAACAGCACAAGCCAGGGAAATT
CAAGCGGAAGGCGCGCAGATTTTAGCCGCAATTGCCCAAAGGATTCAGGAATCTTTGGATTTAGAAACAATCCTTTATCA
AACTGCCAAAGATTTACGACAGTGTTTAAAATGCGATCGCATTCTGATTTATCAAATCAAATCAGACAATAATGGGGCGA
TTGTTGCAGAATCAACTGTATTGCCTGATATTTCCCTCTTGGGAAAACACTTCCGTGATCCTTGCTTTCAAGGTAAAAAT
AAGGAATCTCAGGGGCGATGTTGTCTAGAAATTATTGAAGATATATATGCAGCAGGAGTGAAACCTTGCCAGAGGGATTT
CCTCGCCTCCATGCAGGTGAGGGCGAATATAGTCATGCCAATAGCCTTAAAACCAGACTTATGGGGGCTGTTAATTGCTC
AATACTGCTATGAACCACACCAATGGCAGCAAATAGAAATTGACTTACTCAAGCAACTAGCCACCCAGTTGGGTATAGGC
ATTCAAAATGCGAAACTACAACAGCAACTAAAACAACTGCAAGCCAAGCTAACAACACACAAACATGAGCAGCAAGCCCA
GGTAAAACAGACAGACAAATTTCAAGCACTAGTTTTAAATATTACAGAAAAAACCCGTGATTACGGCGAGGAAACGCAAG
TTTTAGCAACAGTCACTCAAGAATTAGCCAATTTATTCCAACTAGAATCTTGCTACATCGAACTTTATAGCACTGACTGC
ACCGTAGCTAGTGTAGTTCATGAATATGCAGCTAACCAGCCCACATACCAGGGACTCACTAGACAAATTGCAGACTTTAG
CGAAATCTATGAACCACTATTGCAAAAACAGCATTTTCAAACCATAGAAATTGTCCCTGGTTGGCATCCTCAATTACTGG
TTATTACCCAACTGGCTTGTCCCATTTTCGATGCTCAAGGGATGCTGGGTAATCTGTGGCTGATTCGACCCATACAACAA
ATGCTGACTCAATCAGAAATTTGCCTAGTACAAACTTTAGCAAATCTATGTGCGATCGCCATTCGCCAGGCCAAGTTAGA
CGCAACTAACCAAGCACGACTGAAAAAATTAGAACAACGAGAAAACCTGACCAACAAATTTCTCAGAAAACTTTCTCAAG
AACTGCGGACACCAATAACTAGTATTAGCCTAGCAGCGCAAACCCTCGAAACTGTCCTCTCACCCTCAATTACCTTAGAT
GAAATCATCCCCCAGCTTTTACAGATTCTACATAATGAGTGTGGCAGAGAAAGCAAATTAATTAACGACTTGCTGACACT
TACCTATCTACAAACCAAACCAGAACCGCCTACACTCATTTCCATCGACTTCCAAACCTGGCTTCCCCCCATCGTTGAAT
CCTTCCGTGACCTCACCAGTTGTCAGCAACAGCGATTACACCTGATAATTGAGCCAGGCTTACCGCGTTTAGAAACAGAT
ATTACCGAACTAGAGCGGATTCTTACCGAACTACTCAGTCATACCTGCAAATATACTCCGGCTGGCGAATCAATTACAGT
TTCCGCCCAACTCACAGATAATACTGTGCAACTAAGTATTAGCAATTCTGGCTTAGAAATTCCTACTCATGTGCGATCGC
GCATCTTCGAGCCGTTCTATCATATTTCTAACAACGATCCTTGGAAATATAGTGGTACTGGCTTGGAAATGGCATTAGTC
CAGAAAATGGTCAGGCATTTAGGCGGCTCCATTTCTGTCGAGAGTAGTCATGGTCAAACTACTTTTATGATCAGATTTCC
CGCCTCACTCAGCTAA

Upstream 100 bases:

>100_bases
CGAACTAAATTTCACTTTAGGCGCTAAAAAGCATTTTCTACCATGAAATTCCGAGAGAACGCGCCTACACGAGCCAGTAA
AACCAGACAGGGACTCTCGC

Downstream 100 bases:

>100_bases
ATCTTGGCAGAACTACAGAATTTTGTTAATATAGTGATTGGTGTGGGTGACTAGCTCAACGGTAGAGCAGTAGACTCTTA
ATCTATTGGTTGCGGGTTCA

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 751; Mature: 751

Protein sequence:

>751_residues
MNINPVDSAIKLKQQSHPHILFGTEVDEHSSGEQLLLSMYDSVQTSIFVVDVLQDGDFQYVALNPTHERWVGIRSEDLRG
KKPEDILTAVDAAKVRQHYADCVRFGKTISYEQCLQFQGVSTWWSTTLTPLRDTNSKIYRLIGTSSNITAAKQTAQAREI
QAEGAQILAAIAQRIQESLDLETILYQTAKDLRQCLKCDRILIYQIKSDNNGAIVAESTVLPDISLLGKHFRDPCFQGKN
KESQGRCCLEIIEDIYAAGVKPCQRDFLASMQVRANIVMPIALKPDLWGLLIAQYCYEPHQWQQIEIDLLKQLATQLGIG
IQNAKLQQQLKQLQAKLTTHKHEQQAQVKQTDKFQALVLNITEKTRDYGEETQVLATVTQELANLFQLESCYIELYSTDC
TVASVVHEYAANQPTYQGLTRQIADFSEIYEPLLQKQHFQTIEIVPGWHPQLLVITQLACPIFDAQGMLGNLWLIRPIQQ
MLTQSEICLVQTLANLCAIAIRQAKLDATNQARLKKLEQRENLTNKFLRKLSQELRTPITSISLAAQTLETVLSPSITLD
EIIPQLLQILHNECGRESKLINDLLTLTYLQTKPEPPTLISIDFQTWLPPIVESFRDLTSCQQQRLHLIIEPGLPRLETD
ITELERILTELLSHTCKYTPAGESITVSAQLTDNTVQLSISNSGLEIPTHVRSRIFEPFYHISNNDPWKYSGTGLEMALV
QKMVRHLGGSISVESSHGQTTFMIRFPASLS

Sequences:

>Translated_751_residues
MNINPVDSAIKLKQQSHPHILFGTEVDEHSSGEQLLLSMYDSVQTSIFVVDVLQDGDFQYVALNPTHERWVGIRSEDLRG
KKPEDILTAVDAAKVRQHYADCVRFGKTISYEQCLQFQGVSTWWSTTLTPLRDTNSKIYRLIGTSSNITAAKQTAQAREI
QAEGAQILAAIAQRIQESLDLETILYQTAKDLRQCLKCDRILIYQIKSDNNGAIVAESTVLPDISLLGKHFRDPCFQGKN
KESQGRCCLEIIEDIYAAGVKPCQRDFLASMQVRANIVMPIALKPDLWGLLIAQYCYEPHQWQQIEIDLLKQLATQLGIG
IQNAKLQQQLKQLQAKLTTHKHEQQAQVKQTDKFQALVLNITEKTRDYGEETQVLATVTQELANLFQLESCYIELYSTDC
TVASVVHEYAANQPTYQGLTRQIADFSEIYEPLLQKQHFQTIEIVPGWHPQLLVITQLACPIFDAQGMLGNLWLIRPIQQ
MLTQSEICLVQTLANLCAIAIRQAKLDATNQARLKKLEQRENLTNKFLRKLSQELRTPITSISLAAQTLETVLSPSITLD
EIIPQLLQILHNECGRESKLINDLLTLTYLQTKPEPPTLISIDFQTWLPPIVESFRDLTSCQQQRLHLIIEPGLPRLETD
ITELERILTELLSHTCKYTPAGESITVSAQLTDNTVQLSISNSGLEIPTHVRSRIFEPFYHISNNDPWKYSGTGLEMALV
QKMVRHLGGSISVESSHGQTTFMIRFPASLS
>Mature_751_residues
MNINPVDSAIKLKQQSHPHILFGTEVDEHSSGEQLLLSMYDSVQTSIFVVDVLQDGDFQYVALNPTHERWVGIRSEDLRG
KKPEDILTAVDAAKVRQHYADCVRFGKTISYEQCLQFQGVSTWWSTTLTPLRDTNSKIYRLIGTSSNITAAKQTAQAREI
QAEGAQILAAIAQRIQESLDLETILYQTAKDLRQCLKCDRILIYQIKSDNNGAIVAESTVLPDISLLGKHFRDPCFQGKN
KESQGRCCLEIIEDIYAAGVKPCQRDFLASMQVRANIVMPIALKPDLWGLLIAQYCYEPHQWQQIEIDLLKQLATQLGIG
IQNAKLQQQLKQLQAKLTTHKHEQQAQVKQTDKFQALVLNITEKTRDYGEETQVLATVTQELANLFQLESCYIELYSTDC
TVASVVHEYAANQPTYQGLTRQIADFSEIYEPLLQKQHFQTIEIVPGWHPQLLVITQLACPIFDAQGMLGNLWLIRPIQQ
MLTQSEICLVQTLANLCAIAIRQAKLDATNQARLKKLEQRENLTNKFLRKLSQELRTPITSISLAAQTLETVLSPSITLD
EIIPQLLQILHNECGRESKLINDLLTLTYLQTKPEPPTLISIDFQTWLPPIVESFRDLTSCQQQRLHLIIEPGLPRLETD
ITELERILTELLSHTCKYTPAGESITVSAQLTDNTVQLSISNSGLEIPTHVRSRIFEPFYHISNNDPWKYSGTGLEMALV
QKMVRHLGGSISVESSHGQTTFMIRFPASLS

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=250, Percent_Identity=26.4, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1786783, Length=236, Percent_Identity=29.2372881355932, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI48994928, Length=249, Percent_Identity=26.5060240963855, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI1789149, Length=227, Percent_Identity=26.431718061674, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1790861, Length=220, Percent_Identity=25.9090909090909, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788393, Length=232, Percent_Identity=23.2758620689655, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1790436, Length=222, Percent_Identity=24.3243243243243, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI87082128, Length=309, Percent_Identity=22.3300970873786, Blast_Score=68, Evalue=3e-12,
Organism=Escherichia coli, GI1786600, Length=237, Percent_Identity=25.3164556962025, Blast_Score=67, Evalue=6e-12,
Organism=Escherichia coli, GI1786912, Length=279, Percent_Identity=25.089605734767, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 84839; Mature: 84839

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS50109 HIS_KIN ; PS50046 PHYTOCHROME_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNINPVDSAIKLKQQSHPHILFGTEVDEHSSGEQLLLSMYDSVQTSIFVVDVLQDGDFQY
CCCCCCCHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHEEEEEEEEECCCEEE
VALNPTHERWVGIRSEDLRGKKPEDILTAVDAAKVRQHYADCVRFGKTISYEQCLQFQGV
EEECCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCC
STWWSTTLTPLRDTNSKIYRLIGTSSNITAAKQTAQAREIQAEGAQILAAIAQRIQESLD
CHHHHCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LETILYQTAKDLRQCLKCDRILIYQIKSDNNGAIVAESTVLPDISLLGKHFRDPCFQGKN
HHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEECCCCCCCHHHHHHHHCCHHHCCCC
KESQGRCCLEIIEDIYAAGVKPCQRDFLASMQVRANIVMPIALKPDLWGLLIAQYCYEPH
CCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCEEEEEEEECCCHHHHHHHHHHCCCC
QWQQIEIDLLKQLATQLGIGIQNAKLQQQLKQLQAKLTTHKHEQQAQVKQTDKFQALVLN
CCCEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHEEE
ITEKTRDYGEETQVLATVTQELANLFQLESCYIELYSTDCTVASVVHEYAANQPTYQGLT
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHCCCCHHHHHH
RQIADFSEIYEPLLQKQHFQTIEIVPGWHPQLLVITQLACPIFDAQGMLGNLWLIRPIQQ
HHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
MLTQSEICLVQTLANLCAIAIRQAKLDATNQARLKKLEQRENLTNKFLRKLSQELRTPIT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
SISLAAQTLETVLSPSITLDEIIPQLLQILHNECGRESKLINDLLTLTYLQTKPEPPTLI
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCEE
SIDFQTWLPPIVESFRDLTSCQQQRLHLIIEPGLPRLETDITELERILTELLSHTCKYTP
EEEHHHCCHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
AGESITVSAQLTDNTVQLSISNSGLEIPTHVRSRIFEPFYHISNNDPWKYSGTGLEMALV
CCCEEEEEEEEECCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCEECCCCHHHHHH
QKMVRHLGGSISVESSHGQTTFMIRFPASLS
HHHHHHCCCCEEEECCCCCEEEEEECCCCCC
>Mature Secondary Structure
MNINPVDSAIKLKQQSHPHILFGTEVDEHSSGEQLLLSMYDSVQTSIFVVDVLQDGDFQY
CCCCCCCHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHEEEEEEEEECCCEEE
VALNPTHERWVGIRSEDLRGKKPEDILTAVDAAKVRQHYADCVRFGKTISYEQCLQFQGV
EEECCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCC
STWWSTTLTPLRDTNSKIYRLIGTSSNITAAKQTAQAREIQAEGAQILAAIAQRIQESLD
CHHHHCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LETILYQTAKDLRQCLKCDRILIYQIKSDNNGAIVAESTVLPDISLLGKHFRDPCFQGKN
HHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEECCCCCCCHHHHHHHHCCHHHCCCC
KESQGRCCLEIIEDIYAAGVKPCQRDFLASMQVRANIVMPIALKPDLWGLLIAQYCYEPH
CCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCEEEEEEEECCCHHHHHHHHHHCCCC
QWQQIEIDLLKQLATQLGIGIQNAKLQQQLKQLQAKLTTHKHEQQAQVKQTDKFQALVLN
CCCEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHEEE
ITEKTRDYGEETQVLATVTQELANLFQLESCYIELYSTDCTVASVVHEYAANQPTYQGLT
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHCCCCHHHHHH
RQIADFSEIYEPLLQKQHFQTIEIVPGWHPQLLVITQLACPIFDAQGMLGNLWLIRPIQQ
HHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
MLTQSEICLVQTLANLCAIAIRQAKLDATNQARLKKLEQRENLTNKFLRKLSQELRTPIT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
SISLAAQTLETVLSPSITLDEIIPQLLQILHNECGRESKLINDLLTLTYLQTKPEPPTLI
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCEE
SIDFQTWLPPIVESFRDLTSCQQQRLHLIIEPGLPRLETDITELERILTELLSHTCKYTP
EEEHHHCCHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
AGESITVSAQLTDNTVQLSISNSGLEIPTHVRSRIFEPFYHISNNDPWKYSGTGLEMALV
CCCEEEEEEEEECCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCEECCCCHHHHHH
QKMVRHLGGSISVESSHGQTTFMIRFPASLS
HHHHHHCCCCEEEECCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Phosphotransferases with a nitrogenous group as acceptor [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]