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The map label for this gene is yhdP [H]

Identifier: 75908578

GI number: 75908578

Start: 2940067

End: 2941365

Strand: Direct

Name: yhdP [H]

Synonym: Ava_2361

Alternate gene names: 75908578

Gene position: 2940067-2941365 (Clockwise)

Preceding gene: 75908577

Following gene: 75908580

Centisome position: 46.19

GC content: 45.03

Gene sequence:

>1299_bases
TTGCTATCAGTACTGCTGCTGATTGTGATTAATGCTTTTTTTGTCACAGCAGAGTTTTCCATAGTTACTGTGAGGCGATC
GCGCATTCATCAGTTAGTTCAATCTGGGGATATTCAGGCGATCGCCGTGGAGTCACTCCAGCGCAACATTGATCGAGTAT
TATCAACAACCCAATTGGGCATCACCCTCTCTAGTTTAGCCGTGGGTTGGATTGGTGAAAGTTCGATTGCTGTAGTTATG
CGTTGGTGGATCAAATCCTGGCCGTTACCCGCCAATGTGAATAATTTTGTCGCTCATTCTCTGTCAATTCCCATCGCCTT
TTTCTTGATTGCCTATCTACAAATTGTTTTAGGTGAACTGTGTCCCAAATCAGTCGCTATGCTGTACTCAGAACAGCTAG
CACGTTTTTTGGGACCCGCAGTAAAAGCGATCGTGCGTTTTTTCCGCCCCTTTATCTGGATTCTCAACCAATCCACCAGT
TACCTACTGCGGCTATTTGGCGTTGAATATACAGGGCAAAGCTGGCGACCACCGGTAACACCAGAAGAATTACAGTTAAT
CATCTCTACAGAAAGAGAATCAACTGGTTTACAAACGGCAGAAAGAGAACTGCTGAATAACATCTTTGAGTTTGGTGATG
TCACAGCACAAGATGTGATGATTCCCCGCAATGGCATTATCGCCCTATCCAAAGATGCTAACTTCCAAAGCCTACTCCAA
CAGATGACAGCTACCGGACACTCGCGTTACCCCGTGATTGGCGAATCCTTAGATGATATTCGCGGGATTGTCTATTTTAG
AGATTTAGCCAACCCCCTAGCAGTCGGCAAGTTATCTCTAGAAACACAAATTCAACCTTGGATGCGTCCAGCGCGATTTG
TACCCGAACATACCCCCCTCAGTGAACTATTACCTATGATGCAGCAAGAAAAGCCAGCAATGGTCATAGTAGTGGACGAG
TTTGGCGGTACTGTGGGTCTAGTAACAATTCAAGATGTCATTGCGGAAATTATTGGCAATGCTGGTGAAACCTCAAGCAG
CGAAGACTTGCTGATTCAGATGTTAGACCAGGAGACATTTTTAGTGCAAGCCCAGGTCAACTTAGAAGACCTAAACGAAG
TCCTACACCTGAATTTACCCTTAACAAAACAATATCAGACCCTAGCTGGCTTCTTGCTTTATCAATTGCAAAAAATGCCC
ATAAAAGGCGAAATCTTCTGCTACGACAACATCGAATTTACAATAGTCTCCGTTGACGGGCCGAGGCTGCATCAGATTCA
ACTGCGACGCTTGGGTTAG

Upstream 100 bases:

>100_bases
ACCCAATCCCCGATAGCCAACCCCCAGCATCATAAATTTTGCAAAAACTTTGGCGGTGAATGAATTTTCTAATTTGAACT
TGACAGATGTGGGGCTGCGG

Downstream 100 bases:

>100_bases
GGATCAGGGACTTTTCTTAGCTGGGGACTGGGGACTGGGTGAAAAGTCTTGTTGTGTCTAGGTTGTATCATCTATTGATG
TCCTAACACTACTGGCAACA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MLSVLLLIVINAFFVTAEFSIVTVRRSRIHQLVQSGDIQAIAVESLQRNIDRVLSTTQLGITLSSLAVGWIGESSIAVVM
RWWIKSWPLPANVNNFVAHSLSIPIAFFLIAYLQIVLGELCPKSVAMLYSEQLARFLGPAVKAIVRFFRPFIWILNQSTS
YLLRLFGVEYTGQSWRPPVTPEELQLIISTERESTGLQTAERELLNNIFEFGDVTAQDVMIPRNGIIALSKDANFQSLLQ
QMTATGHSRYPVIGESLDDIRGIVYFRDLANPLAVGKLSLETQIQPWMRPARFVPEHTPLSELLPMMQQEKPAMVIVVDE
FGGTVGLVTIQDVIAEIIGNAGETSSSEDLLIQMLDQETFLVQAQVNLEDLNEVLHLNLPLTKQYQTLAGFLLYQLQKMP
IKGEIFCYDNIEFTIVSVDGPRLHQIQLRRLG

Sequences:

>Translated_432_residues
MLSVLLLIVINAFFVTAEFSIVTVRRSRIHQLVQSGDIQAIAVESLQRNIDRVLSTTQLGITLSSLAVGWIGESSIAVVM
RWWIKSWPLPANVNNFVAHSLSIPIAFFLIAYLQIVLGELCPKSVAMLYSEQLARFLGPAVKAIVRFFRPFIWILNQSTS
YLLRLFGVEYTGQSWRPPVTPEELQLIISTERESTGLQTAERELLNNIFEFGDVTAQDVMIPRNGIIALSKDANFQSLLQ
QMTATGHSRYPVIGESLDDIRGIVYFRDLANPLAVGKLSLETQIQPWMRPARFVPEHTPLSELLPMMQQEKPAMVIVVDE
FGGTVGLVTIQDVIAEIIGNAGETSSSEDLLIQMLDQETFLVQAQVNLEDLNEVLHLNLPLTKQYQTLAGFLLYQLQKMP
IKGEIFCYDNIEFTIVSVDGPRLHQIQLRRLG
>Mature_432_residues
MLSVLLLIVINAFFVTAEFSIVTVRRSRIHQLVQSGDIQAIAVESLQRNIDRVLSTTQLGITLSSLAVGWIGESSIAVVM
RWWIKSWPLPANVNNFVAHSLSIPIAFFLIAYLQIVLGELCPKSVAMLYSEQLARFLGPAVKAIVRFFRPFIWILNQSTS
YLLRLFGVEYTGQSWRPPVTPEELQLIISTERESTGLQTAERELLNNIFEFGDVTAQDVMIPRNGIIALSKDANFQSLLQ
QMTATGHSRYPVIGESLDDIRGIVYFRDLANPLAVGKLSLETQIQPWMRPARFVPEHTPLSELLPMMQQEKPAMVIVVDE
FGGTVGLVTIQDVIAEIIGNAGETSSSEDLLIQMLDQETFLVQAQVNLEDLNEVLHLNLPLTKQYQTLAGFLLYQLQKMP
IKGEIFCYDNIEFTIVSVDGPRLHQIQLRRLG

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=393, Percent_Identity=29.7709923664122, Blast_Score=210, Evalue=2e-54,
Organism=Escherichia coli, GI1790664, Length=434, Percent_Identity=24.1935483870968, Blast_Score=158, Evalue=6e-40,
Organism=Escherichia coli, GI145693175, Length=422, Percent_Identity=25.8293838862559, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1786879, Length=254, Percent_Identity=28.3464566929134, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI87082033, Length=296, Percent_Identity=25.6756756756757, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1788119, Length=231, Percent_Identity=25.5411255411255, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 48523; Mature: 48523

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSVLLLIVINAFFVTAEFSIVTVRRSRIHQLVQSGDIQAIAVESLQRNIDRVLSTTQLG
CHHHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHC
ITLSSLAVGWIGESSIAVVMRWWIKSWPLPANVNNFVAHSLSIPIAFFLIAYLQIVLGEL
EEHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
CPKSVAMLYSEQLARFLGPAVKAIVRFFRPFIWILNQSTSYLLRLFGVEYTGQSWRPPVT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCC
PEELQLIISTERESTGLQTAERELLNNIFEFGDVTAQDVMIPRNGIIALSKDANFQSLLQ
HHHHEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHEEECCCCEEEEECCCCHHHHHH
QMTATGHSRYPVIGESLDDIRGIVYFRDLANPLAVGKLSLETQIQPWMRPARFVPEHTPL
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHCCEEEHHHCCHHHHCHHHCCCCCCCH
SELLPMMQQEKPAMVIVVDEFGGTVGLVTIQDVIAEIIGNAGETSSSEDLLIQMLDQETF
HHHHHHHHCCCCCEEEEEECCCCEEEEHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCEE
LVQAQVNLEDLNEVLHLNLPLTKQYQTLAGFLLYQLQKMPIKGEIFCYDNIEFTIVSVDG
EEEEECCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCC
PRLHQIQLRRLG
CCEEHHHHCCCC
>Mature Secondary Structure
MLSVLLLIVINAFFVTAEFSIVTVRRSRIHQLVQSGDIQAIAVESLQRNIDRVLSTTQLG
CHHHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHC
ITLSSLAVGWIGESSIAVVMRWWIKSWPLPANVNNFVAHSLSIPIAFFLIAYLQIVLGEL
EEHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
CPKSVAMLYSEQLARFLGPAVKAIVRFFRPFIWILNQSTSYLLRLFGVEYTGQSWRPPVT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCC
PEELQLIISTERESTGLQTAERELLNNIFEFGDVTAQDVMIPRNGIIALSKDANFQSLLQ
HHHHEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHEEECCCCEEEEECCCCHHHHHH
QMTATGHSRYPVIGESLDDIRGIVYFRDLANPLAVGKLSLETQIQPWMRPARFVPEHTPL
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHCCEEEHHHCCHHHHCHHHCCCCCCCH
SELLPMMQQEKPAMVIVVDEFGGTVGLVTIQDVIAEIIGNAGETSSSEDLLIQMLDQETF
HHHHHHHHCCCCCEEEEEECCCCEEEEHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCEE
LVQAQVNLEDLNEVLHLNLPLTKQYQTLAGFLLYQLQKMPIKGEIFCYDNIEFTIVSVDG
EEEEECCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCC
PRLHQIQLRRLG
CCEEHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]