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The map label for this gene is yfdH [C]

Identifier: 75908563

GI number: 75908563

Start: 2909722

End: 2910705

Strand: Direct

Name: yfdH [C]

Synonym: Ava_2346

Alternate gene names: 75908563

Gene position: 2909722-2910705 (Clockwise)

Preceding gene: 75908562

Following gene: 75908565

Centisome position: 45.71

GC content: 39.84

Gene sequence:

>984_bases
ATGCCGCCTAAATATTCTTTTATCGTCCCGATTTACAACGAAGAAGAAACCATCACAGAAATGTATCGCCGCATTTCCCA
GGTAATGGATCAGATGGATGGTTCAGTCGAGTTGTGTTTAGTTAATGATGGCAGCCGCGATCGCTCTCTGAGAATGATGC
GAGAATTACATCAAAAAGATCCGCGTGTTGTTTACTTAAGTCTTGCCAGAAATTTTGGTCATCAAATCGCCGTTACCGCA
GGTTTAAATTTTGCCCGTGGACAAGTAGTTGTGATTCTCGATGCCGATTTACAAGATCCACCAGAATTGATCGCGGAAAT
GGTGGAATTATGGCGGCAAGGATATCATATAATTTACGCCCAAAGAATCAAACGCCGTCAAGAAGGCTGGTTTAAACGCT
TCACCGCCTATACTTTTTATCGGATTCTCAAACAACTGGCAGATGTTGATATTCCTACAGATACCGGAGACTTTTGTTTA
TTAGATAGGCAAGTTGTTGATGTACTCAATGCTATGCCAGAGCGAAATCGTTACATTCGCGGCTTGCGTTCTTGGGTAGG
TTTTAACCAAACAGCCGTTAAATTTGAACGAGATCCTCGTTTTGCTGGCGATGTTAAATATACATTTCGTAAATCTTTTG
CATTGGCAATTAATGGCATAGTTTCCTTTTCTAAGGTACCATTAAGGCTTTCAACTTATTTAGGACTATTTGCAGCAATA
GCCTCATTATTAATGTGTCTGTTAGTTTTATACTGGCGGATTTTTACACCCCATTCTCCCCTAACTGGAATCACCATTAT
TCTCATCGCTATCTTCTTTTTGGGAGCAGTACAACTGGTGAGTATTGGTATTTTAGGTGAATATATCGGGCGAATTTATG
AAGAGGTTAAACAAAGACCACTTTATACATTGTCAGAAGTTAGCGGCTTTGAGCAGCAATATCCTGATGCTCAACAATCA
TTAGATATTTCTTCATCCAATTAA

Upstream 100 bases:

>100_bases
TGGTGCTTTGGCATTGATTGGAATGCTAGTTGGTGGTTCCACTTGGTATCGTCGTCGTCGCTCTTTTCCCACTCGTAAAA
AACCCTAACACATCTCCACT

Downstream 100 bases:

>100_bases
ATACTAATGAATTATTGGCACTGAGTTCGTAGCTATATTTTCTAACTAGAAACCATCGCTACCTTAATTACCTTCCGCGC
TTTCATATCATCAAATACTT

Product: glycosyl transferase family protein

Products: GDP; dolichyl D-mannosyl phosphate

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MPPKYSFIVPIYNEEETITEMYRRISQVMDQMDGSVELCLVNDGSRDRSLRMMRELHQKDPRVVYLSLARNFGHQIAVTA
GLNFARGQVVVILDADLQDPPELIAEMVELWRQGYHIIYAQRIKRRQEGWFKRFTAYTFYRILKQLADVDIPTDTGDFCL
LDRQVVDVLNAMPERNRYIRGLRSWVGFNQTAVKFERDPRFAGDVKYTFRKSFALAINGIVSFSKVPLRLSTYLGLFAAI
ASLLMCLLVLYWRIFTPHSPLTGITIILIAIFFLGAVQLVSIGILGEYIGRIYEEVKQRPLYTLSEVSGFEQQYPDAQQS
LDISSSN

Sequences:

>Translated_327_residues
MPPKYSFIVPIYNEEETITEMYRRISQVMDQMDGSVELCLVNDGSRDRSLRMMRELHQKDPRVVYLSLARNFGHQIAVTA
GLNFARGQVVVILDADLQDPPELIAEMVELWRQGYHIIYAQRIKRRQEGWFKRFTAYTFYRILKQLADVDIPTDTGDFCL
LDRQVVDVLNAMPERNRYIRGLRSWVGFNQTAVKFERDPRFAGDVKYTFRKSFALAINGIVSFSKVPLRLSTYLGLFAAI
ASLLMCLLVLYWRIFTPHSPLTGITIILIAIFFLGAVQLVSIGILGEYIGRIYEEVKQRPLYTLSEVSGFEQQYPDAQQS
LDISSSN
>Mature_326_residues
PPKYSFIVPIYNEEETITEMYRRISQVMDQMDGSVELCLVNDGSRDRSLRMMRELHQKDPRVVYLSLARNFGHQIAVTAG
LNFARGQVVVILDADLQDPPELIAEMVELWRQGYHIIYAQRIKRRQEGWFKRFTAYTFYRILKQLADVDIPTDTGDFCLL
DRQVVDVLNAMPERNRYIRGLRSWVGFNQTAVKFERDPRFAGDVKYTFRKSFALAINGIVSFSKVPLRLSTYLGLFAAIA
SLLMCLLVLYWRIFTPHSPLTGITIILIAIFFLGAVQLVSIGILGEYIGRIYEEVKQRPLYTLSEVSGFEQQYPDAQQSL
DISSSN

Specific function: Involved In O Antigen Modification. Catalyzes The Transfer Of The Glucose Residue From Udp-Glucose To A Lipid Carrier (By Similarity). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family. GtrB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788692, Length=306, Percent_Identity=40.1960784313725, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI1788588, Length=311, Percent_Identity=31.1897106109325, Blast_Score=167, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI71999402, Length=190, Percent_Identity=30.5263157894737, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: 2.4.1.83

Molecular weight: Translated: 37677; Mature: 37546

Theoretical pI: Translated: 8.39; Mature: 8.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPKYSFIVPIYNEEETITEMYRRISQVMDQMDGSVELCLVNDGSRDRSLRMMRELHQKD
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCC
PRVVYLSLARNFGHQIAVTAGLNFARGQVVVILDADLQDPPELIAEMVELWRQGYHIIYA
CCEEEEEEHHHCCCEEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHH
QRIKRRQEGWFKRFTAYTFYRILKQLADVDIPTDTGDFCLLDRQVVDVLNAMPERNRYIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHCCCCHHHHHH
GLRSWVGFNQTAVKFERDPRFAGDVKYTFRKSFALAINGIVSFSKVPLRLSTYLGLFAAI
HHHHHHCCCCHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ASLLMCLLVLYWRIFTPHSPLTGITIILIAIFFLGAVQLVSIGILGEYIGRIYEEVKQRP
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LYTLSEVSGFEQQYPDAQQSLDISSSN
CHHHHHHCCHHHHCCCHHHCCCCCCCC
>Mature Secondary Structure 
PPKYSFIVPIYNEEETITEMYRRISQVMDQMDGSVELCLVNDGSRDRSLRMMRELHQKD
CCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCC
PRVVYLSLARNFGHQIAVTAGLNFARGQVVVILDADLQDPPELIAEMVELWRQGYHIIYA
CCEEEEEEHHHCCCEEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHH
QRIKRRQEGWFKRFTAYTFYRILKQLADVDIPTDTGDFCLLDRQVVDVLNAMPERNRYIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHCCCCHHHHHH
GLRSWVGFNQTAVKFERDPRFAGDVKYTFRKSFALAINGIVSFSKVPLRLSTYLGLFAAI
HHHHHHCCCCHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ASLLMCLLVLYWRIFTPHSPLTGITIILIAIFFLGAVQLVSIGILGEYIGRIYEEVKQRP
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LYTLSEVSGFEQQYPDAQQSLDISSSN
CHHHHHHCCHHHHCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GDPmannose; dolichyl phosphate

Specific reaction: GDP-mannose + dolichyl phosphate = GDP + dolichyl D-mannosyl phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]