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The map label for this gene is clpB2 [H]

Identifier: 75908552

GI number: 75908552

Start: 2899002

End: 2901620

Strand: Direct

Name: clpB2 [H]

Synonym: Ava_2335

Alternate gene names: 75908552

Gene position: 2899002-2901620 (Clockwise)

Preceding gene: 75908546

Following gene: 75908554

Centisome position: 45.54

GC content: 46.09

Gene sequence:

>2619_bases
ATGCAACCTACTAATCCCAACCAATTTACAGAAAAAGCCTGGGAAGCGATCGCCCACACTCCTGAGATTGCTAAACAGCA
TCAACAGCAGCAGATAGAAAGCGAACATCTGATGAAGGCGCTACTGGAACAAGATGGTTTGGCCAGTGGGATTTTGACCA
AAGCAGGTGTGAACTTACAAAAAATTGGCGATCGCACTGAACAATACATCCAGCGCCAACCGAAAGTCTCAGGTAACAGC
ACCTCAGTCTACCTGGGGCGGAGTCTGGATACACTGTTAGACAGAGCAGAAGCACATCGTAAAGATTTTAAAGACGAATA
TATTTCTATTGAACATTTATTACTGGCTTACCCTAAAGACGATCGCTTCGGCAAAGGTTTATTCCAAGAATTCGCTTTAG
ACGAAGGCAAGCTCAAAAATATTATTAAACAAGTTCGTGGGAGCCAAACAGTGACTGACCAAAATCCAGAAGGCAAATAC
CAATCACTGGAAAAATACGGGCGTGACCTCACAGAAGCAGCCCGGAAAGGTCAACTTGATCCAGTCATTGGGCGTGATGA
TGAGATTCGGCGTACCATCCAAATTCTGTCTCGCCGCACCAAAAATAACCCTGTGTTGATTGGTGAACCGGGTGTAGGTA
AAACAGCGATCGCTGAAGGTTTGGCACAGCGTATCGTGGCTGGTGACGTACCCCAATCTCTCAAAGACCGCAAGCTAATC
TCCTTAGATATGGGGGCGATGATTGCTGGGGCAAAATTCCGAGGAGAATTTGAAGAACGTCTGAAGGCGGTATTAAAAGA
AGTCACCGAATCCGGCGGCAATATAGTTTTATTTATTGATGAAATTCATACTGTTGTCGGTGCGGGTGCAACTCAAGGCG
CGATGGATGCCGGAAACTTGTTAAAACCCATGTTGGCGCGGGGTGAATTGCGCTGTATTGGGGCGACAACTTTGGATGAA
TACCGCAAATATATCGAAAAAGATGCGGCCTTAGAAAGACGCTTCCAACAGGTTTACGTAGACCAGCCCAGTGTTGAAGA
TACCATTTCTATTTTACGTGGCTTGAAGGAACGGTATGAAGTCCACCACGGGGTAAAAATTTCTGATAGTTCCTTAGTAG
CTGCCGCTACGTTGTCCAGTCGTTATATTAGCGATCGCTTCCTCCCAGATAAAGCCATTGACTTGGTAGACGAAGCCGCC
GCTAGACTGAAAATGGAAATTACTTCTAAGCCAGAAGAACTTGATGAAATCGACCGGAAGATTCTGCAATTAGAGATGGA
AAAGCTATCTCTGCAAAAAGAAAGTGATGCAGCTTCCCGCGAACGCCTGGAAAGACTAGAAAAAGAATTAGCAGATCTCA
AGGAAGAACAAAGAACCCTCAATACTCAATGGCAATCGGAAAAAGATGTCATTAATAAACTTCAGTCTGTTAAGGAAGAG
ATTGACAAAGTTAACTTAGAAATTCAGCAAGCAGAAAGAGACTACGACCTCAACCGCGCCGCCGAATTGAAGTATGGAAA
GTTAACCGACTTGCACCGGAGACTGGAAGCAACAGAACGGGAATTGTCACAAACCCAAGGCACGGGTAAATCCCTGTTGC
GAGAAGAAGTCACCGAAGCCGACATTGCGGAAATTATTTCTAAGTGGACAGGAATCCCCATCAGTAAATTAGTGGAATCG
GAGAAAGAAAAACTACTGCACTTAGAAGATGAACTCCATCACCGGGTAATTGGGCAAGATGAAGCCGTCACAGCCGTCGC
CGATGCCATTCAGCGATCGCGTGCTGGTTTGGCTGATCCTAATCGTCCCATTGCTAGTTTTGTTTTCCTGGGGCCGACAG
GTGTAGGTAAAACTGAACTGGCGAAGGCGCTAGCGTCATATATGTTCGACACCGAGGAAGCAATGGTGCGGATTGATATG
TCGGAATATATGGAGAAACACGCCGTTTCTCGGTTAATTGGTGCGCCTCCAGGGTATGTAGGTTACGAAGAAGGGGGACA
ACTCACAGAAGCCATCCGTCGCCGTCCTTATGCTGTGATTCTCTTCGACGAAATCGAGAAAGCCCACCCGGACGTATTTA
ATATTTTCCTGCAAATCCTCGATGATGGTCGCGTTACCGATGCCCAAGGTCATACAGTGGACTTCAAGAACACGATTATT
ATCATGACCAGTAACATCGGTTCCCAGTACATTCTCGATATAGCTGGGGATAACTCACGCTACGATGAAATGCGCCATCG
GGTGATGGAAGCAATGCGAAATAGTTTCCGTCCTGAGTTCCTCAACCGGATTGATGAGGTAATTATCTTCCACGGTTTAG
ATAAGAAAGAATTGCGGCAAATTGTCCAGTTGCAAGTGGAAAGGTTAAAGGCAAGATTAGGCGATCGCAAAATATCTCTC
CGGCTCTCCGATGCTGCACTAGACTTTTTGGCAGAAGTTGGATACGACCCAGTATTTGGGGCGCGTCCACTGAAGCGGGC
GATTCAGCGCGAGTTAGAAACGCAAATCGCTAAGGCGATTTTACGCGGTGAATTTAACGATGGGGACACGATTTTTGTCG
ATGTGCAGAATGAAAGGTTGTCTTTTAGTCGCTTACCTGTTGAGGTGTTTAGTAGTTAA

Upstream 100 bases:

>100_bases
GATCCCGGTGATGGTGCAACTCTCCGTAAAATGACGATATGAGAACAAATTGTTCTATCTGCATTTGAGCATTTAAATTT
GGTCGTCCCTCAATCAGCCT

Downstream 100 bases:

>100_bases
TTAAATCCAGATTGGTTCGCGCAAAGGCGCAAAGGCGCGTCTTTGCGTTTTTTTGTAATTTATCATCAATTTTGAGCCTC
ATGAAACCTGGTTACTACTA

Product: ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 872; Mature: 872

Protein sequence:

>872_residues
MQPTNPNQFTEKAWEAIAHTPEIAKQHQQQQIESEHLMKALLEQDGLASGILTKAGVNLQKIGDRTEQYIQRQPKVSGNS
TSVYLGRSLDTLLDRAEAHRKDFKDEYISIEHLLLAYPKDDRFGKGLFQEFALDEGKLKNIIKQVRGSQTVTDQNPEGKY
QSLEKYGRDLTEAARKGQLDPVIGRDDEIRRTIQILSRRTKNNPVLIGEPGVGKTAIAEGLAQRIVAGDVPQSLKDRKLI
SLDMGAMIAGAKFRGEFEERLKAVLKEVTESGGNIVLFIDEIHTVVGAGATQGAMDAGNLLKPMLARGELRCIGATTLDE
YRKYIEKDAALERRFQQVYVDQPSVEDTISILRGLKERYEVHHGVKISDSSLVAAATLSSRYISDRFLPDKAIDLVDEAA
ARLKMEITSKPEELDEIDRKILQLEMEKLSLQKESDAASRERLERLEKELADLKEEQRTLNTQWQSEKDVINKLQSVKEE
IDKVNLEIQQAERDYDLNRAAELKYGKLTDLHRRLEATERELSQTQGTGKSLLREEVTEADIAEIISKWTGIPISKLVES
EKEKLLHLEDELHHRVIGQDEAVTAVADAIQRSRAGLADPNRPIASFVFLGPTGVGKTELAKALASYMFDTEEAMVRIDM
SEYMEKHAVSRLIGAPPGYVGYEEGGQLTEAIRRRPYAVILFDEIEKAHPDVFNIFLQILDDGRVTDAQGHTVDFKNTII
IMTSNIGSQYILDIAGDNSRYDEMRHRVMEAMRNSFRPEFLNRIDEVIIFHGLDKKELRQIVQLQVERLKARLGDRKISL
RLSDAALDFLAEVGYDPVFGARPLKRAIQRELETQIAKAILRGEFNDGDTIFVDVQNERLSFSRLPVEVFSS

Sequences:

>Translated_872_residues
MQPTNPNQFTEKAWEAIAHTPEIAKQHQQQQIESEHLMKALLEQDGLASGILTKAGVNLQKIGDRTEQYIQRQPKVSGNS
TSVYLGRSLDTLLDRAEAHRKDFKDEYISIEHLLLAYPKDDRFGKGLFQEFALDEGKLKNIIKQVRGSQTVTDQNPEGKY
QSLEKYGRDLTEAARKGQLDPVIGRDDEIRRTIQILSRRTKNNPVLIGEPGVGKTAIAEGLAQRIVAGDVPQSLKDRKLI
SLDMGAMIAGAKFRGEFEERLKAVLKEVTESGGNIVLFIDEIHTVVGAGATQGAMDAGNLLKPMLARGELRCIGATTLDE
YRKYIEKDAALERRFQQVYVDQPSVEDTISILRGLKERYEVHHGVKISDSSLVAAATLSSRYISDRFLPDKAIDLVDEAA
ARLKMEITSKPEELDEIDRKILQLEMEKLSLQKESDAASRERLERLEKELADLKEEQRTLNTQWQSEKDVINKLQSVKEE
IDKVNLEIQQAERDYDLNRAAELKYGKLTDLHRRLEATERELSQTQGTGKSLLREEVTEADIAEIISKWTGIPISKLVES
EKEKLLHLEDELHHRVIGQDEAVTAVADAIQRSRAGLADPNRPIASFVFLGPTGVGKTELAKALASYMFDTEEAMVRIDM
SEYMEKHAVSRLIGAPPGYVGYEEGGQLTEAIRRRPYAVILFDEIEKAHPDVFNIFLQILDDGRVTDAQGHTVDFKNTII
IMTSNIGSQYILDIAGDNSRYDEMRHRVMEAMRNSFRPEFLNRIDEVIIFHGLDKKELRQIVQLQVERLKARLGDRKISL
RLSDAALDFLAEVGYDPVFGARPLKRAIQRELETQIAKAILRGEFNDGDTIFVDVQNERLSFSRLPVEVFSS
>Mature_872_residues
MQPTNPNQFTEKAWEAIAHTPEIAKQHQQQQIESEHLMKALLEQDGLASGILTKAGVNLQKIGDRTEQYIQRQPKVSGNS
TSVYLGRSLDTLLDRAEAHRKDFKDEYISIEHLLLAYPKDDRFGKGLFQEFALDEGKLKNIIKQVRGSQTVTDQNPEGKY
QSLEKYGRDLTEAARKGQLDPVIGRDDEIRRTIQILSRRTKNNPVLIGEPGVGKTAIAEGLAQRIVAGDVPQSLKDRKLI
SLDMGAMIAGAKFRGEFEERLKAVLKEVTESGGNIVLFIDEIHTVVGAGATQGAMDAGNLLKPMLARGELRCIGATTLDE
YRKYIEKDAALERRFQQVYVDQPSVEDTISILRGLKERYEVHHGVKISDSSLVAAATLSSRYISDRFLPDKAIDLVDEAA
ARLKMEITSKPEELDEIDRKILQLEMEKLSLQKESDAASRERLERLEKELADLKEEQRTLNTQWQSEKDVINKLQSVKEE
IDKVNLEIQQAERDYDLNRAAELKYGKLTDLHRRLEATERELSQTQGTGKSLLREEVTEADIAEIISKWTGIPISKLVES
EKEKLLHLEDELHHRVIGQDEAVTAVADAIQRSRAGLADPNRPIASFVFLGPTGVGKTELAKALASYMFDTEEAMVRIDM
SEYMEKHAVSRLIGAPPGYVGYEEGGQLTEAIRRRPYAVILFDEIEKAHPDVFNIFLQILDDGRVTDAQGHTVDFKNTII
IMTSNIGSQYILDIAGDNSRYDEMRHRVMEAMRNSFRPEFLNRIDEVIIFHGLDKKELRQIVQLQVERLKARLGDRKISL
RLSDAALDFLAEVGYDPVFGARPLKRAIQRELETQIAKAILRGEFNDGDTIFVDVQNERLSFSRLPVEVFSS

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=321, Percent_Identity=38.3177570093458, Blast_Score=212, Evalue=1e-54,
Organism=Escherichia coli, GI1788943, Length=855, Percent_Identity=56.9590643274854, Blast_Score=991, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=403, Percent_Identity=40.1985111662531, Blast_Score=286, Evalue=3e-78,
Organism=Saccharomyces cerevisiae, GI6320464, Length=715, Percent_Identity=53.1468531468531, Blast_Score=793, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=865, Percent_Identity=43.5838150289017, Blast_Score=689, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 98478; Mature: 98478

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPTNPNQFTEKAWEAIAHTPEIAKQHQQQQIESEHLMKALLEQDGLASGILTKAGVNLQ
CCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHH
KIGDRTEQYIQRQPKVSGNSTSVYLGRSLDTLLDRAEAHRKDFKDEYISIEHLLLAYPKD
HHHHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
DRFGKGLFQEFALDEGKLKNIIKQVRGSQTVTDQNPEGKYQSLEKYGRDLTEAARKGQLD
CCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHCCCCC
PVIGRDDEIRRTIQILSRRTKNNPVLIGEPGVGKTAIAEGLAQRIVAGDVPQSLKDRKLI
CCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHCCCEE
SLDMGAMIAGAKFRGEFEERLKAVLKEVTESGGNIVLFIDEIHTVVGAGATQGAMDAGNL
EECHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCHHHH
LKPMLARGELRCIGATTLDEYRKYIEKDAALERRFQQVYVDQPSVEDTISILRGLKERYE
HHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
VHHGVKISDSSLVAAATLSSRYISDRFLPDKAIDLVDEAAARLKMEITSKPEELDEIDRK
HHCCCEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEHHHCCCCHHHHHHHHH
ILQLEMEKLSLQKESDAASRERLERLEKELADLKEEQRTLNTQWQSEKDVINKLQSVKEE
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
IDKVNLEIQQAERDYDLNRAAELKYGKLTDLHRRLEATERELSQTQGTGKSLLREEVTEA
HHHHCCHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
DIAEIISKWTGIPISKLVESEKEKLLHLEDELHHRVIGQDEAVTAVADAIQRSRAGLADP
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCC
NRPIASFVFLGPTGVGKTELAKALASYMFDTEEAMVRIDMSEYMEKHAVSRLIGAPPGYV
CCCHHHEEEECCCCCCHHHHHHHHHHHHHCCHHHHEEECHHHHHHHHHHHHHHCCCCCCC
GYEEGGQLTEAIRRRPYAVILFDEIEKAHPDVFNIFLQILDDGRVTDAQGHTVDFKNTII
CCCCCCHHHHHHHHCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCEECCCCCEEECCCEEE
IMTSNIGSQYILDIAGDNSRYDEMRHRVMEAMRNSFRPEFLNRIDEVIIFHGLDKKELRQ
EEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHH
IVQLQVERLKARLGDRKISLRLSDAALDFLAEVGYDPVFGARPLKRAIQRELETQIAKAI
HHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LRGEFNDGDTIFVDVQNERLSFSRLPVEVFSS
HHCCCCCCCEEEEEECCCCCCHHHCCHHHHCC
>Mature Secondary Structure
MQPTNPNQFTEKAWEAIAHTPEIAKQHQQQQIESEHLMKALLEQDGLASGILTKAGVNLQ
CCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHH
KIGDRTEQYIQRQPKVSGNSTSVYLGRSLDTLLDRAEAHRKDFKDEYISIEHLLLAYPKD
HHHHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
DRFGKGLFQEFALDEGKLKNIIKQVRGSQTVTDQNPEGKYQSLEKYGRDLTEAARKGQLD
CCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHCCCCC
PVIGRDDEIRRTIQILSRRTKNNPVLIGEPGVGKTAIAEGLAQRIVAGDVPQSLKDRKLI
CCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHCCCEE
SLDMGAMIAGAKFRGEFEERLKAVLKEVTESGGNIVLFIDEIHTVVGAGATQGAMDAGNL
EECHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCHHHH
LKPMLARGELRCIGATTLDEYRKYIEKDAALERRFQQVYVDQPSVEDTISILRGLKERYE
HHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
VHHGVKISDSSLVAAATLSSRYISDRFLPDKAIDLVDEAAARLKMEITSKPEELDEIDRK
HHCCCEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEHHHCCCCHHHHHHHHH
ILQLEMEKLSLQKESDAASRERLERLEKELADLKEEQRTLNTQWQSEKDVINKLQSVKEE
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
IDKVNLEIQQAERDYDLNRAAELKYGKLTDLHRRLEATERELSQTQGTGKSLLREEVTEA
HHHHCCHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
DIAEIISKWTGIPISKLVESEKEKLLHLEDELHHRVIGQDEAVTAVADAIQRSRAGLADP
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCC
NRPIASFVFLGPTGVGKTELAKALASYMFDTEEAMVRIDMSEYMEKHAVSRLIGAPPGYV
CCCHHHEEEECCCCCCHHHHHHHHHHHHHCCHHHHEEECHHHHHHHHHHHHHHCCCCCCC
GYEEGGQLTEAIRRRPYAVILFDEIEKAHPDVFNIFLQILDDGRVTDAQGHTVDFKNTII
CCCCCCHHHHHHHHCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCEECCCCCEEECCCEEE
IMTSNIGSQYILDIAGDNSRYDEMRHRVMEAMRNSFRPEFLNRIDEVIIFHGLDKKELRQ
EEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHH
IVQLQVERLKARLGDRKISLRLSDAALDFLAEVGYDPVFGARPLKRAIQRELETQIAKAI
HHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LRGEFNDGDTIFVDVQNERLSFSRLPVEVFSS
HHCCCCCCCEEEEEECCCCCCHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]