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The map label for this gene is holB [H]

Identifier: 75908184

GI number: 75908184

Start: 2440029

End: 2440991

Strand: Direct

Name: holB [H]

Synonym: Ava_1963

Alternate gene names: 75908184

Gene position: 2440029-2440991 (Clockwise)

Preceding gene: 75908183

Following gene: 75908185

Centisome position: 38.33

GC content: 44.65

Gene sequence:

>963_bases
ATGACCAATAACCCGTTTGCACCACTGGTAGGACAAAAGCAAGCTATTGAGTTATTAACTCAAGCTGTTAAGCAAAACCG
AGTAGCCCCGGCTTATCTATTTGCGGGGCCAGATGGTGTAGGACGGAGTTTAGCGGCGCGTTGCTTTGTAGAGTTGTTAT
TTGCATCTGTTGTGGAAGCGCGACTTCTTCCATCTTTACAACAGCGTTTACGTCAAGGTAATCACCCTGATTTACTGTGG
GTACAGCCAACTTATCAATACCAAGGGCAAAGATTCACCGCCGCCCAAGCAGCAGAAAAGAAACTCAAACGCAAAGCACC
GCCTTTAATTCGCCTAGAACAAATTCGAGAAATTACAGAATTTCTCAGCCGTCCTCCCTTAGAAGCACCAAGAAATGTGG
TGGTGTTGGAGGAAGCGCAAACAATGGCGGAACCAGCCGCAAATGCTTTGTTGAAGACGTTAGAAGAACCAGGACAAGCA
ACCATAGTTTTGATTACGCCTTCCCCTGAGTCTGTATTGCCGACTTTGGTGTCACGCTGTCAACGCATTCCCTTTTACAG
TTTAGATACAACATCTTTGACTCAAGTACTTACGCAAACCGGGAATCAAGCAGTTTTACAGCACCCAGCCCTGTTGAGTT
TAGCATCTGGTAGCCCAGGGAGTGCGATCGCCTCTTATGAACAATTACAAACTATTCCCCCTGACTTACTGCAAGATTTA
ACAACAGCACCAAAATCTCAACGTCACGCGTTGGAATTAGCTAAGAGAATCGACAAGGATTTAGAAACGGAAGCACAACT
ATGGTTAGTGGATTATTTACAGCAATCCTACTGGCAAAAGCGGCATCTACCAGGGATTATCAGTCAACTAGAAAAAGCTC
GTAAATACCTACTGGTCTACGCTCAACCGCGCCTCGTTTGGGAATGTACTTTATTATCTGTATATCAGGAATTTAATATC
TAA

Upstream 100 bases:

>100_bases
TTCAGCTAAATCTAACCACAAAACATGGAAAAACGACGACTATTAAGACAAATACGTAAAAAATTAAATAAGCTTTATAT
GAAATTTTAATTACTCAAGA

Downstream 100 bases:

>100_bases
CTACTGGACAATTAATCCTCAACTGCGATACATCTTTTCTGGAAGAATGCAATTGTACAAAATACAGCTATAGAAATGAT
GGAAACTGCAACTGCTGACA

Product: DNA polymerase III subunit delta'

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MTNNPFAPLVGQKQAIELLTQAVKQNRVAPAYLFAGPDGVGRSLAARCFVELLFASVVEARLLPSLQQRLRQGNHPDLLW
VQPTYQYQGQRFTAAQAAEKKLKRKAPPLIRLEQIREITEFLSRPPLEAPRNVVVLEEAQTMAEPAANALLKTLEEPGQA
TIVLITPSPESVLPTLVSRCQRIPFYSLDTTSLTQVLTQTGNQAVLQHPALLSLASGSPGSAIASYEQLQTIPPDLLQDL
TTAPKSQRHALELAKRIDKDLETEAQLWLVDYLQQSYWQKRHLPGIISQLEKARKYLLVYAQPRLVWECTLLSVYQEFNI

Sequences:

>Translated_320_residues
MTNNPFAPLVGQKQAIELLTQAVKQNRVAPAYLFAGPDGVGRSLAARCFVELLFASVVEARLLPSLQQRLRQGNHPDLLW
VQPTYQYQGQRFTAAQAAEKKLKRKAPPLIRLEQIREITEFLSRPPLEAPRNVVVLEEAQTMAEPAANALLKTLEEPGQA
TIVLITPSPESVLPTLVSRCQRIPFYSLDTTSLTQVLTQTGNQAVLQHPALLSLASGSPGSAIASYEQLQTIPPDLLQDL
TTAPKSQRHALELAKRIDKDLETEAQLWLVDYLQQSYWQKRHLPGIISQLEKARKYLLVYAQPRLVWECTLLSVYQEFNI
>Mature_319_residues
TNNPFAPLVGQKQAIELLTQAVKQNRVAPAYLFAGPDGVGRSLAARCFVELLFASVVEARLLPSLQQRLRQGNHPDLLWV
QPTYQYQGQRFTAAQAAEKKLKRKAPPLIRLEQIREITEFLSRPPLEAPRNVVVLEEAQTMAEPAANALLKTLEEPGQAT
IVLITPSPESVLPTLVSRCQRIPFYSLDTTSLTQVLTQTGNQAVLQHPALLSLASGSPGSAIASYEQLQTIPPDLLQDLT
TAPKSQRHALELAKRIDKDLETEAQLWLVDYLQQSYWQKRHLPGIISQLEKARKYLLVYAQPRLVWECTLLSVYQEFNI

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG0470

COG function: function code L; ATPase involved in DNA replication

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004622 [H]

Pfam domain/function: NA

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 35833; Mature: 35702

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNNPFAPLVGQKQAIELLTQAVKQNRVAPAYLFAGPDGVGRSLAARCFVELLFASVVEA
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
RLLPSLQQRLRQGNHPDLLWVQPTYQYQGQRFTAAQAAEKKLKRKAPPLIRLEQIREITE
HHHHHHHHHHHCCCCCCEEEECCCHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
FLSRPPLEAPRNVVVLEEAQTMAEPAANALLKTLEEPGQATIVLITPSPESVLPTLVSRC
HHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHH
QRIPFYSLDTTSLTQVLTQTGNQAVLQHPALLSLASGSPGSAIASYEQLQTIPPDLLQDL
HHCCCCCCCHHHHHHHHHHCCCHHHHHCCHHEEECCCCCCHHHHHHHHHHCCCHHHHHHH
TTAPKSQRHALELAKRIDKDLETEAQLWLVDYLQQSYWQKRHLPGIISQLEKARKYLLVY
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEEE
AQPRLVWECTLLSVYQEFNI
ECCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TNNPFAPLVGQKQAIELLTQAVKQNRVAPAYLFAGPDGVGRSLAARCFVELLFASVVEA
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
RLLPSLQQRLRQGNHPDLLWVQPTYQYQGQRFTAAQAAEKKLKRKAPPLIRLEQIREITE
HHHHHHHHHHHCCCCCCEEEECCCHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
FLSRPPLEAPRNVVVLEEAQTMAEPAANALLKTLEEPGQATIVLITPSPESVLPTLVSRC
HHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHH
QRIPFYSLDTTSLTQVLTQTGNQAVLQHPALLSLASGSPGSAIASYEQLQTIPPDLLQDL
HHCCCCCCCHHHHHHHHHHCCCHHHHHCCHHEEECCCCCCHHHHHHHHHHCCCHHHHHHH
TTAPKSQRHALELAKRIDKDLETEAQLWLVDYLQQSYWQKRHLPGIISQLEKARKYLLVY
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEEE
AQPRLVWECTLLSVYQEFNI
ECCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]