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The map label for this gene is cdsA [H]

Identifier: 75908039

GI number: 75908039

Start: 2264032

End: 2265030

Strand: Direct

Name: cdsA [H]

Synonym: Ava_1818

Alternate gene names: 75908039

Gene position: 2264032-2265030 (Clockwise)

Preceding gene: 75908038

Following gene: 75908041

Centisome position: 35.57

GC content: 43.44

Gene sequence:

>999_bases
ATGAGAATGGAGAGTAGGGGGAGCAAAAGAGAAAACAAACCCCCAGTACCCAATCCCCAGTACCCAATCCCCATTACCCC
TTATCCCCAGTACCCAACCCCGAATACTTCTATGCCTTGGTCTCGGATTATTAGTGGAATTGTTGCGATCGCCCTTGCTT
TAGTTGCTGTCCTGTTGGGGGGTTGGTATTTCACCATCATGCTGGCGATTGTTGTTTTCTTAGGACAACAGGAATATTTT
GATTTAGTTCGCACTAGAGGTATTTTGCCAGCTGCGAAAACCACTTTATTCCTTAGTCAAGTTTTACTAGTTACTTGTAC
TGTGGACAGCAATTTAGTTGATGCTGTCATGCCTATTGCAGGTACATTTATTTGCTTTTATTTACTATTTCAACCGAAAA
TGGCCACAATCGCCGATGTTTCGGCATCGATTATGGGGCTTTTTTATGTCGGGTACTTACCGAGTTATTGGGTGCGGTTG
CGTTCAATTGGTACCACAGCCATCAGTAATTTACCTTTAGGGGGCTACTGGCCAGGAAGTTTGACAGATATTCTTGAAGA
AAGAAATTTTGCCTCTCTACCCCAAGGTTTGAAAATCACAGTGCTGACATTTCTGTGCATCTGGGCAGCAGACATTGGTG
CATATACTATTGGTAAATTCTTCGGCAAAACTCGTCTGTCTGATATCAGCCCGAAAAAAACAGTGGAAGGTGCTGTTTTT
GGGATCAGTGCTAGTTTAGCAGTAGCTCTGGCTGGCGCTTACTACCTTCACTTACCCAAATTTCTTTTGACTGGAACAAT
TTTAGGCTTACTAATTGGCTTGGCTAGTCTTTTGGGCGATCTTACTGAGTCAATGCTAAAGCGTGATGCTGGTGTAAAGG
ACTCTGGACAATTGATCCCCGGTCATGGTGGCATTTTAGATCGCACAGATAGTTATATCTTCACTGCCCCTTTGGTTTAC
TATTTCGTCACGCTCATTTTGCCATTGCTTAGTCAATAG

Upstream 100 bases:

>100_bases
TAGAAACACGAGGATTTTCTCAAACCTTTGCCGCAGTTGATCCCATTTTTATCCTCAGTGGTGAGAAACTAGACTAGGGA
CTGGGGACTAGGAAGAGTAG

Downstream 100 bases:

>100_bases
TTCAGTGGTCAGTGGTCAGTGGTCAGTGGTCAGTGGTCAGTTATCATTCTTCTTTACTTCCCTTGATCCCCCTGCCTCCT
GCCCACTCTATAATCACGGA

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MRMESRGSKRENKPPVPNPQYPIPITPYPQYPTPNTSMPWSRIISGIVAIALALVAVLLGGWYFTIMLAIVVFLGQQEYF
DLVRTRGILPAAKTTLFLSQVLLVTCTVDSNLVDAVMPIAGTFICFYLLFQPKMATIADVSASIMGLFYVGYLPSYWVRL
RSIGTTAISNLPLGGYWPGSLTDILEERNFASLPQGLKITVLTFLCIWAADIGAYTIGKFFGKTRLSDISPKKTVEGAVF
GISASLAVALAGAYYLHLPKFLLTGTILGLLIGLASLLGDLTESMLKRDAGVKDSGQLIPGHGGILDRTDSYIFTAPLVY
YFVTLILPLLSQ

Sequences:

>Translated_332_residues
MRMESRGSKRENKPPVPNPQYPIPITPYPQYPTPNTSMPWSRIISGIVAIALALVAVLLGGWYFTIMLAIVVFLGQQEYF
DLVRTRGILPAAKTTLFLSQVLLVTCTVDSNLVDAVMPIAGTFICFYLLFQPKMATIADVSASIMGLFYVGYLPSYWVRL
RSIGTTAISNLPLGGYWPGSLTDILEERNFASLPQGLKITVLTFLCIWAADIGAYTIGKFFGKTRLSDISPKKTVEGAVF
GISASLAVALAGAYYLHLPKFLLTGTILGLLIGLASLLGDLTESMLKRDAGVKDSGQLIPGHGGILDRTDSYIFTAPLVY
YFVTLILPLLSQ
>Mature_332_residues
MRMESRGSKRENKPPVPNPQYPIPITPYPQYPTPNTSMPWSRIISGIVAIALALVAVLLGGWYFTIMLAIVVFLGQQEYF
DLVRTRGILPAAKTTLFLSQVLLVTCTVDSNLVDAVMPIAGTFICFYLLFQPKMATIADVSASIMGLFYVGYLPSYWVRL
RSIGTTAISNLPLGGYWPGSLTDILEERNFASLPQGLKITVLTFLCIWAADIGAYTIGKFFGKTRLSDISPKKTVEGAVF
GISASLAVALAGAYYLHLPKFLLTGTILGLLIGLASLLGDLTESMLKRDAGVKDSGQLIPGHGGILDRTDSYIFTAPLVY
YFVTLILPLLSQ

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=134, Percent_Identity=42.5373134328358, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787677, Length=117, Percent_Identity=46.1538461538462, Blast_Score=95, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 36131; Mature: 36131

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMESRGSKRENKPPVPNPQYPIPITPYPQYPTPNTSMPWSRIISGIVAIALALVAVLLG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
GWYFTIMLAIVVFLGQQEYFDLVRTRGILPAAKTTLFLSQVLLVTCTVDSNLVDAVMPIA
HHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
GTFICFYLLFQPKMATIADVSASIMGLFYVGYLPSYWVRLRSIGTTAISNLPLGGYWPGS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
LTDILEERNFASLPQGLKITVLTFLCIWAADIGAYTIGKFFGKTRLSDISPKKTVEGAVF
HHHHHHHCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
GISASLAVALAGAYYLHLPKFLLTGTILGLLIGLASLLGDLTESMLKRDAGVKDSGQLIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GHGGILDRTDSYIFTAPLVYYFVTLILPLLSQ
CCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRMESRGSKRENKPPVPNPQYPIPITPYPQYPTPNTSMPWSRIISGIVAIALALVAVLLG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
GWYFTIMLAIVVFLGQQEYFDLVRTRGILPAAKTTLFLSQVLLVTCTVDSNLVDAVMPIA
HHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
GTFICFYLLFQPKMATIADVSASIMGLFYVGYLPSYWVRLRSIGTTAISNLPLGGYWPGS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
LTDILEERNFASLPQGLKITVLTFLCIWAADIGAYTIGKFFGKTRLSDISPKKTVEGAVF
HHHHHHHCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
GISASLAVALAGAYYLHLPKFLLTGTILGLLIGLASLLGDLTESMLKRDAGVKDSGQLIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GHGGILDRTDSYIFTAPLVYYFVTLILPLLSQ
CCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]