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The map label for this gene is sucD2 [H]

Identifier: 75908005

GI number: 75908005

Start: 2226713

End: 2227594

Strand: Direct

Name: sucD2 [H]

Synonym: Ava_1784

Alternate gene names: 75908005

Gene position: 2226713-2227594 (Clockwise)

Preceding gene: 75908004

Following gene: 75908009

Centisome position: 34.98

GC content: 44.33

Gene sequence:

>882_bases
ATGAACTTAACGCCAGATAGTAAAGTTATTATTCAAGGCTTCCATGAATTCATTTCGGAGAATCATATTGCCCAGATGAA
AGCCTATGGTACAAATTTGGTAGCCGGTGTTCAGCCTGGATACGGTGGACAGGAACTTTATCATCTGCCTGTTTTTGATT
TGGTTGAGGAGGTAGTAGGGCAATTTGGCAGTATTGACACCACAATTATCTGTGTACACCCTTATCAAGTACTAGATGCG
GCCTTAGAGGCGATCGCCTCTCATATCCGACAAATTATTATTATTTCTGCTGGTGTGCCACCTTTGGATATGGTGGAATT
ACTCCGCAAAGCTGAAGCCGGTGAAACTCTGGTAGTCGGTCCCAACAGTCCCGGAATCATTGTCCCAGGAAAAATCCTCT
TGGGTACTCAACCAAGTGAATTTTACACACCTGGAGTAGTAGGTATTGTTAGCCGTAGCAGTACTTTGACTTATGAAGTG
GCGCGAGAATTAACTCAAGCTGGCTGGGGACAATCAATTAGTGTGAGCATTGGTAGTGATGCGATTGTCGGTTCATCATT
TCTGCAATGGTTACAAATTCTCGATGAGGATGAAACGACTGAGGCGATCGTTTTAGTCGGACAACCAGGTGGGGGTAGTG
AAGAAGCAGCCGCACGATACATTACCGAAGCAATTGATAAACCAGTAATTGCTTATATCGCCGGCAGACAAGCACCACCG
GGAAAAACTTGGCGACAAACTGGCACTTTAGCGACTGTTGTCGGTCGTCCACCTAATTTTGGCACTGCTCAAAGTAAAAT
AACAGCTTTTGAAGCAGCCGAAGTTCCTGTTGCGGAACGTCCTTCTTTGATTCCCCAATTATTAAAAAAGGCAATTCATT
AA

Upstream 100 bases:

>100_bases
GTGTTGAGCAGCTTCCTGAATGCTGAGTTAAGAGGATATCATTAATTCGTAGTTCCCCTTGGGTCTGTGCTACCTTTCCC
CAATTCCCATCCCTCACCTT

Downstream 100 bases:

>100_bases
TCAAAATTTATGAGTTGCTTTTCGGTGAACAGCATGGCAATTCCTTTCTCATAATAGGCGGCTTCGTTGATAAATATGGG
GTAAACTATCGATGTACCTT

Product: succinyl-CoA synthetase (ADP-forming)subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha 2; SCS-alpha 2 [H]

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MNLTPDSKVIIQGFHEFISENHIAQMKAYGTNLVAGVQPGYGGQELYHLPVFDLVEEVVGQFGSIDTTIICVHPYQVLDA
ALEAIASHIRQIIIISAGVPPLDMVELLRKAEAGETLVVGPNSPGIIVPGKILLGTQPSEFYTPGVVGIVSRSSTLTYEV
ARELTQAGWGQSISVSIGSDAIVGSSFLQWLQILDEDETTEAIVLVGQPGGGSEEAAARYITEAIDKPVIAYIAGRQAPP
GKTWRQTGTLATVVGRPPNFGTAQSKITAFEAAEVPVAERPSLIPQLLKKAIH

Sequences:

>Translated_293_residues
MNLTPDSKVIIQGFHEFISENHIAQMKAYGTNLVAGVQPGYGGQELYHLPVFDLVEEVVGQFGSIDTTIICVHPYQVLDA
ALEAIASHIRQIIIISAGVPPLDMVELLRKAEAGETLVVGPNSPGIIVPGKILLGTQPSEFYTPGVVGIVSRSSTLTYEV
ARELTQAGWGQSISVSIGSDAIVGSSFLQWLQILDEDETTEAIVLVGQPGGGSEEAAARYITEAIDKPVIAYIAGRQAPP
GKTWRQTGTLATVVGRPPNFGTAQSKITAFEAAEVPVAERPSLIPQLLKKAIH
>Mature_293_residues
MNLTPDSKVIIQGFHEFISENHIAQMKAYGTNLVAGVQPGYGGQELYHLPVFDLVEEVVGQFGSIDTTIICVHPYQVLDA
ALEAIASHIRQIIIISAGVPPLDMVELLRKAEAGETLVVGPNSPGIIVPGKILLGTQPSEFYTPGVVGIVSRSSTLTYEV
ARELTQAGWGQSISVSIGSDAIVGSSFLQWLQILDEDETTEAIVLVGQPGGGSEEAAARYITEAIDKPVIAYIAGRQAPP
GKTWRQTGTLATVVGRPPNFGTAQSKITAFEAAEVPVAERPSLIPQLLKKAIH

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=242, Percent_Identity=40.0826446280992, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI38569423, Length=255, Percent_Identity=27.843137254902, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI38569421, Length=256, Percent_Identity=26.953125, Blast_Score=82, Evalue=7e-16,
Organism=Escherichia coli, GI1786949, Length=284, Percent_Identity=44.0140845070423, Blast_Score=214, Evalue=5e-57,
Organism=Caenorhabditis elegans, GI17553126, Length=295, Percent_Identity=37.9661016949153, Blast_Score=165, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17550194, Length=289, Percent_Identity=37.7162629757785, Blast_Score=164, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI17557344, Length=211, Percent_Identity=28.436018957346, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17551266, Length=211, Percent_Identity=27.0142180094787, Blast_Score=68, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6324716, Length=295, Percent_Identity=36.271186440678, Blast_Score=154, Evalue=2e-38,
Organism=Drosophila melanogaster, GI21356559, Length=287, Percent_Identity=36.2369337979094, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI28574296, Length=297, Percent_Identity=37.3737373737374, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI281363477, Length=249, Percent_Identity=25.7028112449799, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281363475, Length=249, Percent_Identity=25.7028112449799, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281363473, Length=249, Percent_Identity=25.7028112449799, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 31158; Mature: 31158

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLTPDSKVIIQGFHEFISENHIAQMKAYGTNLVAGVQPGYGGQELYHLPVFDLVEEVVG
CCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCEEEECCCCCCCCEEEECCHHHHHHHHHH
QFGSIDTTIICVHPYQVLDAALEAIASHIRQIIIISAGVPPLDMVELLRKAEAGETLVVG
HCCCCCEEEEEECCHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHCCCCCEEEEC
PNSPGIIVPGKILLGTQPSEFYTPGVVGIVSRSSTLTYEVARELTQAGWGQSISVSIGSD
CCCCCEEECCEEEECCCCCHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEEEECCCC
AIVGSSFLQWLQILDEDETTEAIVLVGQPGGGSEEAAARYITEAIDKPVIAYIAGRQAPP
HHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCC
GKTWRQTGTLATVVGRPPNFGTAQSKITAFEAAEVPVAERPSLIPQLLKKAIH
CCCHHHCCCEEEEECCCCCCCCCHHHHEEHHHCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MNLTPDSKVIIQGFHEFISENHIAQMKAYGTNLVAGVQPGYGGQELYHLPVFDLVEEVVG
CCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCEEEECCCCCCCCEEEECCHHHHHHHHHH
QFGSIDTTIICVHPYQVLDAALEAIASHIRQIIIISAGVPPLDMVELLRKAEAGETLVVG
HCCCCCEEEEEECCHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHCCCCCEEEEC
PNSPGIIVPGKILLGTQPSEFYTPGVVGIVSRSSTLTYEVARELTQAGWGQSISVSIGSD
CCCCCEEECCEEEECCCCCHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEEEECCCC
AIVGSSFLQWLQILDEDETTEAIVLVGQPGGGSEEAAARYITEAIDKPVIAYIAGRQAPP
HHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCC
GKTWRQTGTLATVVGRPPNFGTAQSKITAFEAAEVPVAERPSLIPQLLKKAIH
CCCHHHCCCEEEEECCCCCCCCCHHHHEEHHHCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]