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The map label for this gene is prmA [H]

Identifier: 75676552

GI number: 75676552

Start: 2587694

End: 2588659

Strand: Direct

Name: prmA [H]

Synonym: Nwi_2367

Alternate gene names: 75676552

Gene position: 2587694-2588659 (Clockwise)

Preceding gene: 75676551

Following gene: 75676553

Centisome position: 76.06

GC content: 68.43

Gene sequence:

>966_bases
TTGCCAAATATATCTGAGTTAAGGTCCTCCGGGATCCTTACCCTTCCCCGGATATGCTCTGGACTGCCGATGACCACTGA
AATTTCGCCGGCGACGAGCCGCGCCGCCTTCGCCATCGGGGCGGAGCAAGTCGCGCGGCGGGCCGTCGATTTCCTGAGCG
AGAGCCTGGAGGACGGCGAAACCGCGGTGACCGCGTTCGAACGCAGCGACGGCTGCTGGAGCGTCGCGGTTCACTTCGCC
GACCCGCCGGATGAAGCGCGTGTCCGCGCGCTGGTCGCTCTCGCCGCCGGCGATGACGTCGCCCGGACCGTCGTCTTTGA
CACCATCGCCGCCAGGGATTGGGTCGAGGCCAGCCTCGAAGGGTTGGCGCCGGTCCCCGCCGGGCGCTTCATCGTCCACG
GCCGGCATGACCGCGACCGCGTGCCGCCGAACAAACTGGCGATCGAGATCGAGGCCGCGCTGGCGTTCGGCACCGGCCAT
CACGGCACCACCCGAGGCTGCCTGCTGCTCCTCGATCACGTTCTCCGCGCCAGGATGCCGCGACGCGTCCTCGATCTTGG
CGCAGGGACAGGTGTTCTGGCCATCGCCGCCGCCAAGGCGCTGCACCGGAGCGTGCTGGCCAGCGATATCGACCCGCGCT
CGGCGACGGTGGCGCGGGAAAACGCTACGCTGAACGGAGTCGGCAGTCTTGTCTGGTCGATCCGCGCGACCGGCTTTTCC
GCGCCGTTGTTTCGCGCGCGCGCGCCGTTCGATCTGGTGCTGGCGAACATTCTCGCCAACCCGCTGCGGCGGATGGCTCC
GGCCATGGCGCGCCATCTCGCGCCCGAAGCCATGGTGATCCTCTCCGGGCTGCTGCCGCAGCATACCCGCGGCGTCATCG
CGGCCTACCGCGCGCAGGGGCTGGTGTTGATCCGGCAGTTGCGGATCGACGGATGGTGCAGCCTGCTGATGCAGAACAGA
GGGTGA

Upstream 100 bases:

>100_bases
TGGGAGAGTGGCGGCATCATCGCGGTTCTGAAAGGCTGGCTTGTGATGGTATTCGCTATCCTGCTGGTCGCCGGACCGGC
CTATGGAGTCGGCTATCTCA

Downstream 100 bases:

>100_bases
CTCGCCGGCTTGTTGCATGGCTGCACGCGAACGGGGTCCACTTCGCTCGAAAACGCTATATGATGCCGGCAATGTTCGAG
GCCTATTTCCAGACATTCGA

Product: ribosomal L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MPNISELRSSGILTLPRICSGLPMTTEISPATSRAAFAIGAEQVARRAVDFLSESLEDGETAVTAFERSDGCWSVAVHFA
DPPDEARVRALVALAAGDDVARTVVFDTIAARDWVEASLEGLAPVPAGRFIVHGRHDRDRVPPNKLAIEIEAALAFGTGH
HGTTRGCLLLLDHVLRARMPRRVLDLGAGTGVLAIAAAKALHRSVLASDIDPRSATVARENATLNGVGSLVWSIRATGFS
APLFRARAPFDLVLANILANPLRRMAPAMARHLAPEAMVILSGLLPQHTRGVIAAYRAQGLVLIRQLRIDGWCSLLMQNR
G

Sequences:

>Translated_321_residues
MPNISELRSSGILTLPRICSGLPMTTEISPATSRAAFAIGAEQVARRAVDFLSESLEDGETAVTAFERSDGCWSVAVHFA
DPPDEARVRALVALAAGDDVARTVVFDTIAARDWVEASLEGLAPVPAGRFIVHGRHDRDRVPPNKLAIEIEAALAFGTGH
HGTTRGCLLLLDHVLRARMPRRVLDLGAGTGVLAIAAAKALHRSVLASDIDPRSATVARENATLNGVGSLVWSIRATGFS
APLFRARAPFDLVLANILANPLRRMAPAMARHLAPEAMVILSGLLPQHTRGVIAAYRAQGLVLIRQLRIDGWCSLLMQNR
G
>Mature_320_residues
PNISELRSSGILTLPRICSGLPMTTEISPATSRAAFAIGAEQVARRAVDFLSESLEDGETAVTAFERSDGCWSVAVHFAD
PPDEARVRALVALAAGDDVARTVVFDTIAARDWVEASLEGLAPVPAGRFIVHGRHDRDRVPPNKLAIEIEAALAFGTGHH
GTTRGCLLLLDHVLRARMPRRVLDLGAGTGVLAIAAAKALHRSVLASDIDPRSATVARENATLNGVGSLVWSIRATGFSA
PLFRARAPFDLVLANILANPLRRMAPAMARHLAPEAMVILSGLLPQHTRGVIAAYRAQGLVLIRQLRIDGWCSLLMQNRG

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=210, Percent_Identity=31.4285714285714, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 34294; Mature: 34163

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNISELRSSGILTLPRICSGLPMTTEISPATSRAAFAIGAEQVARRAVDFLSESLEDGE
CCCHHHHHHCCCEEHHHHHCCCCCCCCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHCCCC
TAVTAFERSDGCWSVAVHFADPPDEARVRALVALAAGDDVARTVVFDTIAARDWVEASLE
HHEEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
GLAPVPAGRFIVHGRHDRDRVPPNKLAIEIEAALAFGTGHHGTTRGCLLLLDHVLRARMP
CCCCCCCCCEEEECCCCCCCCCCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCC
RRVLDLGAGTGVLAIAAAKALHRSVLASDIDPRSATVARENATLNGVGSLVWSIRATGFS
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHCCCC
APLFRARAPFDLVLANILANPLRRMAPAMARHLAPEAMVILSGLLPQHTRGVIAAYRAQG
CCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHH
LVLIRQLRIDGWCSLLMQNRG
HHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PNISELRSSGILTLPRICSGLPMTTEISPATSRAAFAIGAEQVARRAVDFLSESLEDGE
CCHHHHHHCCCEEHHHHHCCCCCCCCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHCCCC
TAVTAFERSDGCWSVAVHFADPPDEARVRALVALAAGDDVARTVVFDTIAARDWVEASLE
HHEEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
GLAPVPAGRFIVHGRHDRDRVPPNKLAIEIEAALAFGTGHHGTTRGCLLLLDHVLRARMP
CCCCCCCCCEEEECCCCCCCCCCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCC
RRVLDLGAGTGVLAIAAAKALHRSVLASDIDPRSATVARENATLNGVGSLVWSIRATGFS
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHCCCC
APLFRARAPFDLVLANILANPLRRMAPAMARHLAPEAMVILSGLLPQHTRGVIAAYRAQG
CCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHH
LVLIRQLRIDGWCSLLMQNRG
HHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]