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The map label for this gene is foxA [H]

Identifier: 75676503

GI number: 75676503

Start: 2535457

End: 2537796

Strand: Direct

Name: foxA [H]

Synonym: Nwi_2318

Alternate gene names: 75676503

Gene position: 2535457-2537796 (Clockwise)

Preceding gene: 75676502

Following gene: 75676504

Centisome position: 74.53

GC content: 63.16

Gene sequence:

>2340_bases
ATGTCGAACGATACCGCCCTCGGCCGGGGTGGCGCGCTTTGCTGCGTGCTCGCAACCGTGGCCGCGATCGAATCCTGCTC
GACTGCTTCGGCGCAGTCGAATTCCGATACCGTGCTGCCGGCGGTGACGATCACCGAACCGGCCCGGCAACCCCTTCGGT
CCCAGCCAAACCGCGCCTTCCGCGCCTCCGCCGCACGACGCGCAACGCATCAATCGGCTTCGCGAACCCCCGCGGTCACG
CCGTCAGCCGCCCTCCCCGCCACCGCGCCCGGCACGATGAATGCGGAAGGAGCGCCGGGCCCGCTGAATCTCGGTATCCC
GAATGCGGCCGGCAGCCTCGTTGGGCTGACGCCGCGCGAGACGCCGGCGACCGTCAACATCATCACACAGCGGGATATGC
AGGAAAAAGGCCTCCGCACGATGGTGGAAACCTTCAACTCGGTTCCGGGCGTCATGTCCGGAAACCTCCCCGGCGAACCC
GGCGTCATCTCCATGCGCGGGTTCTCCCGCGCAGCGACCGGATATGCGGTCGACGGCGTTCGCGCGCCAGACCCGTTGAT
CGTCTCCCGCGATTTCGACACCTTCAGTTTCGAGCGTGTCGAAATCCTGAAAGGACCCGCGTCCGTCATTCAGGGTGTCG
GCGCCTTGGCCGGAGCCGTGAATCTTGTAACCAAGCAGCCCAAGCTCGGCCAGGCAGGCGCCCAGGGCCTGTTGAGCTAT
GGCAGCTTCAACTCGCTGCGGACGGGCATCGATATCAACGCTCCGATCGGATCAAACGCGGCCGTCCGCTCGACGCTGAG
CTACGGACAATCCGACGGCTTTATCAACGACACCCGATCGCGCAAGGTGGGCGCAACGACCAGCGGGACGCTCGCCCCGA
CCGACAGGCTCACCTTCACAAGCTCCGCCAGCTTCTTTCACGACGAGTTCCGGACACCCTATCAGGGCACCCCGCTGATC
GCCCGCTCGCTCGCGCGCGATCCCACGAACCTCGTCTCGGCCCCCGGCGGGCTTGTGATCGACCGTTCCATCCGCAATCA
GAACTATAATGTCGAGAATGGGCTGATGACGTCGGACACTGTCTGGCTGCGCGGCGGCGCCGAATACAAGCTGACCGACA
ACTGGACACTGCGGAACGATCTCAGTTTCTTCAAGTCCGACCGGTACTGGGCCAGTTCCGAAGACTTCACGTTCAATTCC
GTGAGCGGCCTGCTCGACCGTTCGACAACGAAAATCACGCACGCGCACCAGATCTGGTCGGAGCGTGCGGCGGCGGCCTA
TGACGGCATCATCGGAGGATTCCGCAACCGCTTCGCTGCCGGGCTCGAATACACCGACACGGATTTCGACTCGAGCAGAC
GGTTCGGATCCGCCACGCCGGTCGATCCCTTCAATCCGGATCGCGGCTACTTCCCTGCCGATACGGCTGCGAACTTCCCG
ACCCGACAGGATTTCACCAGCGGACTAAAAACGTTCGCAGCCTTCGCGGAGAACGCCATCAACCTGACGCCGGACTGGCT
GATGCTCGCCAGCGTCCGGCACGAGAGCATGAAGCTCGATCGACGGATCGACGATCTGAACACGGGTACGGTCACCCGCT
TCGAAAAGACGTTCGACAATCTCTCGTGGCGGGTCGGAACGGTTTACAACGTAACGTCCGGAACGGCCTTATTCGGCCAG
TATAATCGCGCCGCCATTCCGGTCTCGGGGCTGTTGCTCAGCAATCTCGCCAACGGACGGTTCGACCTGTCCACCGGAAG
TTCGATCGAGGGCGGAATCAAATCGTCGCTCTTGGACAACCGTTTGGTGACGACCGCTTCGGTCTATCAGATCGAGCAGA
ACAATATCCTGACCCGCGATCCGACAACTCCGGCGCTGACGGTGCAGGGCGGCAGCCAGCGCTCCCGCGGCGTGGAACTG
GATGTCGCGGTATCACTGACGCCGCAGTGGAGAGTGAACGCGAACGCGTCATTCATCAAGGCGGAGTTTACCGAGTTGCG
TAGCGCCACGCTCGATCTGCGCGGGAACCGCCCGATCAACGTGCCGGCGCAGGCGTTCATGGTCTCGACCAGCTATCGCT
TCGATCCGGTGCCGCTGACAATCGGCGCATCGGCGCAGCACGTAGGGTCTTTCTACACCGACACCGCCAACACCATCGAG
GTAAGCGGGCGAACCCTGCTTGACGCCTGGGTGGCCTACGACATCGGCGGCGGAACGTTGCGGCTGCGCGGCCGCAATCT
CACCAACGCATTCTATGCGAACTGGTCCGGATACAGTCCCACCCAGGTGTATCTCGGCGCGCCGCGCAATTTCGACCTCT
CCTACAACGTCAGGTTCTGA

Upstream 100 bases:

>100_bases
CAACAAATCCGCTCGACCGCCGCGACACCTTCGCGTTCGCGGCGGTCCGATCTGTTTGAACGCTCCGGGCGATAGCCCGC
ATCAGGAAACAAAATACATC

Downstream 100 bases:

>100_bases
TGCGTGAAACACGGCGTCTCGCCGGTGCTCCGATGAGGCGTCCCCATTCCGATGTCTGAAAGCAAACGCCGATGTCCAAC
TCCTTCTCAGCCCTGGCTCT

Product: TonB-dependent siderophore receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 779; Mature: 778

Protein sequence:

>779_residues
MSNDTALGRGGALCCVLATVAAIESCSTASAQSNSDTVLPAVTITEPARQPLRSQPNRAFRASAARRATHQSASRTPAVT
PSAALPATAPGTMNAEGAPGPLNLGIPNAAGSLVGLTPRETPATVNIITQRDMQEKGLRTMVETFNSVPGVMSGNLPGEP
GVISMRGFSRAATGYAVDGVRAPDPLIVSRDFDTFSFERVEILKGPASVIQGVGALAGAVNLVTKQPKLGQAGAQGLLSY
GSFNSLRTGIDINAPIGSNAAVRSTLSYGQSDGFINDTRSRKVGATTSGTLAPTDRLTFTSSASFFHDEFRTPYQGTPLI
ARSLARDPTNLVSAPGGLVIDRSIRNQNYNVENGLMTSDTVWLRGGAEYKLTDNWTLRNDLSFFKSDRYWASSEDFTFNS
VSGLLDRSTTKITHAHQIWSERAAAAYDGIIGGFRNRFAAGLEYTDTDFDSSRRFGSATPVDPFNPDRGYFPADTAANFP
TRQDFTSGLKTFAAFAENAINLTPDWLMLASVRHESMKLDRRIDDLNTGTVTRFEKTFDNLSWRVGTVYNVTSGTALFGQ
YNRAAIPVSGLLLSNLANGRFDLSTGSSIEGGIKSSLLDNRLVTTASVYQIEQNNILTRDPTTPALTVQGGSQRSRGVEL
DVAVSLTPQWRVNANASFIKAEFTELRSATLDLRGNRPINVPAQAFMVSTSYRFDPVPLTIGASAQHVGSFYTDTANTIE
VSGRTLLDAWVAYDIGGGTLRLRGRNLTNAFYANWSGYSPTQVYLGAPRNFDLSYNVRF

Sequences:

>Translated_779_residues
MSNDTALGRGGALCCVLATVAAIESCSTASAQSNSDTVLPAVTITEPARQPLRSQPNRAFRASAARRATHQSASRTPAVT
PSAALPATAPGTMNAEGAPGPLNLGIPNAAGSLVGLTPRETPATVNIITQRDMQEKGLRTMVETFNSVPGVMSGNLPGEP
GVISMRGFSRAATGYAVDGVRAPDPLIVSRDFDTFSFERVEILKGPASVIQGVGALAGAVNLVTKQPKLGQAGAQGLLSY
GSFNSLRTGIDINAPIGSNAAVRSTLSYGQSDGFINDTRSRKVGATTSGTLAPTDRLTFTSSASFFHDEFRTPYQGTPLI
ARSLARDPTNLVSAPGGLVIDRSIRNQNYNVENGLMTSDTVWLRGGAEYKLTDNWTLRNDLSFFKSDRYWASSEDFTFNS
VSGLLDRSTTKITHAHQIWSERAAAAYDGIIGGFRNRFAAGLEYTDTDFDSSRRFGSATPVDPFNPDRGYFPADTAANFP
TRQDFTSGLKTFAAFAENAINLTPDWLMLASVRHESMKLDRRIDDLNTGTVTRFEKTFDNLSWRVGTVYNVTSGTALFGQ
YNRAAIPVSGLLLSNLANGRFDLSTGSSIEGGIKSSLLDNRLVTTASVYQIEQNNILTRDPTTPALTVQGGSQRSRGVEL
DVAVSLTPQWRVNANASFIKAEFTELRSATLDLRGNRPINVPAQAFMVSTSYRFDPVPLTIGASAQHVGSFYTDTANTIE
VSGRTLLDAWVAYDIGGGTLRLRGRNLTNAFYANWSGYSPTQVYLGAPRNFDLSYNVRF
>Mature_778_residues
SNDTALGRGGALCCVLATVAAIESCSTASAQSNSDTVLPAVTITEPARQPLRSQPNRAFRASAARRATHQSASRTPAVTP
SAALPATAPGTMNAEGAPGPLNLGIPNAAGSLVGLTPRETPATVNIITQRDMQEKGLRTMVETFNSVPGVMSGNLPGEPG
VISMRGFSRAATGYAVDGVRAPDPLIVSRDFDTFSFERVEILKGPASVIQGVGALAGAVNLVTKQPKLGQAGAQGLLSYG
SFNSLRTGIDINAPIGSNAAVRSTLSYGQSDGFINDTRSRKVGATTSGTLAPTDRLTFTSSASFFHDEFRTPYQGTPLIA
RSLARDPTNLVSAPGGLVIDRSIRNQNYNVENGLMTSDTVWLRGGAEYKLTDNWTLRNDLSFFKSDRYWASSEDFTFNSV
SGLLDRSTTKITHAHQIWSERAAAAYDGIIGGFRNRFAAGLEYTDTDFDSSRRFGSATPVDPFNPDRGYFPADTAANFPT
RQDFTSGLKTFAAFAENAINLTPDWLMLASVRHESMKLDRRIDDLNTGTVTRFEKTFDNLSWRVGTVYNVTSGTALFGQY
NRAAIPVSGLLLSNLANGRFDLSTGSSIEGGIKSSLLDNRLVTTASVYQIEQNNILTRDPTTPALTVQGGSQRSRGVELD
VAVSLTPQWRVNANASFIKAEFTELRSATLDLRGNRPINVPAQAFMVSTSYRFDPVPLTIGASAQHVGSFYTDTANTIEV
SGRTLLDAWVAYDIGGGTLRLRGRNLTNAFYANWSGYSPTQVYLGAPRNFDLSYNVRF

Specific function: Ferrioxamine binding and uptake, in association with the tonB protein. May play a role in intestinal colonization [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1787024, Length=727, Percent_Identity=23.6588720770289, Blast_Score=116, Evalue=7e-27,
Organism=Escherichia coli, GI1786344, Length=283, Percent_Identity=27.208480565371, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1787344, Length=247, Percent_Identity=25.1012145748988, Blast_Score=76, Evalue=9e-15,
Organism=Escherichia coli, GI1788478, Length=120, Percent_Identity=36.6666666666667, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 83648; Mature: 83517

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNDTALGRGGALCCVLATVAAIESCSTASAQSNSDTVLPAVTITEPARQPLRSQPNRAF
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCHHHHHHHCCCCHHH
RASAARRATHQSASRTPAVTPSAALPATAPGTMNAEGAPGPLNLGIPNAAGSLVGLTPRE
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCEEECCCCC
TPATVNIITQRDMQEKGLRTMVETFNSVPGVMSGNLPGEPGVISMRGFSRAATGYAVDGV
CCCEEEEEECCCHHHHHHHHHHHHHHCCCCCEECCCCCCCCEEEECCCCCCCCCEEECCC
RAPDPLIVSRDFDTFSFERVEILKGPASVIQGVGALAGAVNLVTKQPKLGQAGAQGLLSY
CCCCCEEEECCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHC
GSFNSLRTGIDINAPIGSNAAVRSTLSYGQSDGFINDTRSRKVGATTSGTLAPTDRLTFT
CCCCHHHCCCEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
SSASFFHDEFRTPYQGTPLIARSLARDPTNLVSAPGGLVIDRSIRNQNYNVENGLMTSDT
CCCHHHHHHHCCCCCCCHHHHHHHCCCCHHHHCCCCCEEEEECCCCCCCCCCCCEEECCE
VWLRGGAEYKLTDNWTLRNDLSFFKSDRYWASSEDFTFNSVSGLLDRSTTKITHAHQIWS
EEEECCCEEEEECCCEECCCHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHH
ERAAAAYDGIIGGFRNRFAAGLEYTDTDFDSSRRFGSATPVDPFNPDRGYFPADTAANFP
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TRQDFTSGLKTFAAFAENAINLTPDWLMLASVRHESMKLDRRIDDLNTGTVTRFEKTFDN
CHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHC
LSWRVGTVYNVTSGTALFGQYNRAAIPVSGLLLSNLANGRFDLSTGSSIEGGIKSSLLDN
CCEEEEEEEEECCCEEEEECCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHCC
RLVTTASVYQIEQNNILTRDPTTPALTVQGGSQRSRGVELDVAVSLTPQWRVNANASFIK
CCEEEEEEEEEECCCEEECCCCCCEEEEECCCCCCCCEEEEEEEEECCCEEECCCCHHHH
AEFTELRSATLDLRGNRPINVPAQAFMVSTSYRFDPVPLTIGASAQHVGSFYTDTANTIE
HHHHHHHHHEEEECCCCCCCCCCCEEEEECCCCCCCEEEEECCCHHHHCCEECCCCCEEE
VSGRTLLDAWVAYDIGGGTLRLRGRNLTNAFYANWSGYSPTQVYLGAPRNFDLSYNVRF
ECCCEEEEEEEEEECCCCEEEEECCCCCCEEEECCCCCCCCEEEEECCCCCCEEEEECC
>Mature Secondary Structure 
SNDTALGRGGALCCVLATVAAIESCSTASAQSNSDTVLPAVTITEPARQPLRSQPNRAF
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCHHHHHHHCCCCHHH
RASAARRATHQSASRTPAVTPSAALPATAPGTMNAEGAPGPLNLGIPNAAGSLVGLTPRE
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCEEECCCCC
TPATVNIITQRDMQEKGLRTMVETFNSVPGVMSGNLPGEPGVISMRGFSRAATGYAVDGV
CCCEEEEEECCCHHHHHHHHHHHHHHCCCCCEECCCCCCCCEEEECCCCCCCCCEEECCC
RAPDPLIVSRDFDTFSFERVEILKGPASVIQGVGALAGAVNLVTKQPKLGQAGAQGLLSY
CCCCCEEEECCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHC
GSFNSLRTGIDINAPIGSNAAVRSTLSYGQSDGFINDTRSRKVGATTSGTLAPTDRLTFT
CCCCHHHCCCEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
SSASFFHDEFRTPYQGTPLIARSLARDPTNLVSAPGGLVIDRSIRNQNYNVENGLMTSDT
CCCHHHHHHHCCCCCCCHHHHHHHCCCCHHHHCCCCCEEEEECCCCCCCCCCCCEEECCE
VWLRGGAEYKLTDNWTLRNDLSFFKSDRYWASSEDFTFNSVSGLLDRSTTKITHAHQIWS
EEEECCCEEEEECCCEECCCHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHH
ERAAAAYDGIIGGFRNRFAAGLEYTDTDFDSSRRFGSATPVDPFNPDRGYFPADTAANFP
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TRQDFTSGLKTFAAFAENAINLTPDWLMLASVRHESMKLDRRIDDLNTGTVTRFEKTFDN
CHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHC
LSWRVGTVYNVTSGTALFGQYNRAAIPVSGLLLSNLANGRFDLSTGSSIEGGIKSSLLDN
CCEEEEEEEEECCCEEEEECCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHCC
RLVTTASVYQIEQNNILTRDPTTPALTVQGGSQRSRGVELDVAVSLTPQWRVNANASFIK
CCEEEEEEEEEECCCEEECCCCCCEEEEECCCCCCCCEEEEEEEEECCCEEECCCCHHHH
AEFTELRSATLDLRGNRPINVPAQAFMVSTSYRFDPVPLTIGASAQHVGSFYTDTANTIE
HHHHHHHHHEEEECCCCCCCCCCCEEEEECCCCCCCEEEEECCCHHHHCCEECCCCCEEE
VSGRTLLDAWVAYDIGGGTLRLRGRNLTNAFYANWSGYSPTQVYLGAPRNFDLSYNVRF
ECCCEEEEEEEEEECCCCEEEEECCCCCCEEEECCCCCCCCEEEEECCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677609; 10103258; 7642488 [H]