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The map label for this gene is pksS [H]

Identifier: 75676464

GI number: 75676464

Start: 2488894

End: 2490090

Strand: Direct

Name: pksS [H]

Synonym: Nwi_2279

Alternate gene names: 75676464

Gene position: 2488894-2490090 (Clockwise)

Preceding gene: 75676459

Following gene: 75676465

Centisome position: 73.16

GC content: 62.82

Gene sequence:

>1197_bases
ATGTCCAGCCCTGCCCCCGTCACCGACTGGGTTCACGATTTTGACCATACCGACCCTCGCTGGACCGAAAATCCTTACCC
GATCTGGGACGATCTGCGCGCCAGGTGTCCCATCGCTCACACCAACCGCTTTCTCGGGGTCTACCTGCCGACCACCTATG
AGGCGGTCAAGGAAATCTCCCGCGACACCGAGCATTTTTCTTCGCGCCGCGTAGTGGTTCGCAATTTCCGCCCGGAGCCG
CCGCCGCCGGCGCCGCCGATCACATCGGACCCGCCCGCGCACAAGCACGCCAAGCAGATCCTGCTCCCGCCTTTTGCGCC
GGAAGCCGTGGCGAAGCTGAAGCCGAGGATACGCGCGATCTGCAATGAACTGATCGACGGCTTCATAAACGAGAAAGGCT
GCGACGCGGCGGCCCGCTATACGCGATACATTCCGACCCGCGCCATCACCATCATGCTGGGCGTCCCGGAAAAGGACGGC
GATCTCTTCATCAAGTGGATTCACGAGATACTTGAAGTCGGCCTGAATGATGACGCGGCGGTGATGCAGGCCGTTCGTGA
AATGGTCGGCTATTTCGCCGAGCAGATCGAAGCAAGAAAGAAGCACCCGACCGACGACCTGATCGCGACATTGATGAATG
CGCGGAGCGAGGACGGGCAACCGCTGACGGATATGCACGTCCAGGGCGCTCTGCGGTTGCTGCTGGTCGCCGGCATCGAC
ACCGCGTGGAGCGCCATCGGCTCCTCGTTGTGGCATCTCGCGCAAACGCCGGCGGATCGCGAGCGTCTCATCGCAGAACC
CGAACTGATACCGACCGCCATCGAGGAATTCCTGCGCGCTTTCGCGCCGGCCACATCGGGGCGCGAGGTCATGAAAGAAA
CCACCGTGAGCGGCTGTCCGATGAAGCCCGGCAACATGGTGCTGCTGTCCTTCCCGGCCGCCAACCGCGACCCGGCTGTC
TTTCCCGATGCGGACAAGATCATCATCGACCGCAAGGAGAACCGCCACATCGCTTTCGGCGTCGGCATCCATCGCTGCGT
CGGCGCTCACCTTGCCCGCATGGAGATGCTTGTTGCGATCGAGGAGTGGCTCAAACGAATTCCGGAGTTCCGGCTTGATC
CGTCGGGCGGGGTGAAGTGGTCCGAGGGCAGCGTGCGCGGCCCACGCCAGCTTCCGCTGCTGCTCGGCAAGGCTTGA

Upstream 100 bases:

>100_bases
AGATCGCTCTCATTATCGAGAAGGACCGAGGTCGTATTTTGATAGTTCAAGCGCCAGCGATCCGGCGTCGGACGGTGGCG
ATCATTTCCCGGAGGAATCG

Downstream 100 bases:

>100_bases
AGTCTGATTCGACTGCGCAAAAGAAGGAAGCCAGACGTGCCGCACGAACGTTTCCAGTTTTCGGGATCAGGCGGTCATAA
ACTCGCCGCCACGCTGGACC

Product: cytochrome P450

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MSSPAPVTDWVHDFDHTDPRWTENPYPIWDDLRARCPIAHTNRFLGVYLPTTYEAVKEISRDTEHFSSRRVVVRNFRPEP
PPPAPPITSDPPAHKHAKQILLPPFAPEAVAKLKPRIRAICNELIDGFINEKGCDAAARYTRYIPTRAITIMLGVPEKDG
DLFIKWIHEILEVGLNDDAAVMQAVREMVGYFAEQIEARKKHPTDDLIATLMNARSEDGQPLTDMHVQGALRLLLVAGID
TAWSAIGSSLWHLAQTPADRERLIAEPELIPTAIEEFLRAFAPATSGREVMKETTVSGCPMKPGNMVLLSFPAANRDPAV
FPDADKIIIDRKENRHIAFGVGIHRCVGAHLARMEMLVAIEEWLKRIPEFRLDPSGGVKWSEGSVRGPRQLPLLLGKA

Sequences:

>Translated_398_residues
MSSPAPVTDWVHDFDHTDPRWTENPYPIWDDLRARCPIAHTNRFLGVYLPTTYEAVKEISRDTEHFSSRRVVVRNFRPEP
PPPAPPITSDPPAHKHAKQILLPPFAPEAVAKLKPRIRAICNELIDGFINEKGCDAAARYTRYIPTRAITIMLGVPEKDG
DLFIKWIHEILEVGLNDDAAVMQAVREMVGYFAEQIEARKKHPTDDLIATLMNARSEDGQPLTDMHVQGALRLLLVAGID
TAWSAIGSSLWHLAQTPADRERLIAEPELIPTAIEEFLRAFAPATSGREVMKETTVSGCPMKPGNMVLLSFPAANRDPAV
FPDADKIIIDRKENRHIAFGVGIHRCVGAHLARMEMLVAIEEWLKRIPEFRLDPSGGVKWSEGSVRGPRQLPLLLGKA
>Mature_397_residues
SSPAPVTDWVHDFDHTDPRWTENPYPIWDDLRARCPIAHTNRFLGVYLPTTYEAVKEISRDTEHFSSRRVVVRNFRPEPP
PPAPPITSDPPAHKHAKQILLPPFAPEAVAKLKPRIRAICNELIDGFINEKGCDAAARYTRYIPTRAITIMLGVPEKDGD
LFIKWIHEILEVGLNDDAAVMQAVREMVGYFAEQIEARKKHPTDDLIATLMNARSEDGQPLTDMHVQGALRLLLVAGIDT
AWSAIGSSLWHLAQTPADRERLIAEPELIPTAIEEFLRAFAPATSGREVMKETTVSGCPMKPGNMVLLSFPAANRDPAVF
PDADKIIIDRKENRHIAFGVGIHRCVGAHLARMEMLVAIEEWLKRIPEFRLDPSGGVKWSEGSVRGPRQLPLLLGKA

Specific function: Involved in the metabolism of the antibiotic polyketide bacillaene which is involved in secondary metabolism. The substrate is dihydrobacillaene [H]

COG id: COG2124

COG function: function code Q; Cytochrome P450

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001128
- InterPro:   IPR002397
- InterPro:   IPR017972 [H]

Pfam domain/function: PF00067 p450 [H]

EC number: NA

Molecular weight: Translated: 44485; Mature: 44354

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSPAPVTDWVHDFDHTDPRWTENPYPIWDDLRARCPIAHTNRFLGVYLPTTYEAVKEIS
CCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCHHCCCEEEEECCCHHHHHHHHH
RDTEHFSSRRVVVRNFRPEPPPPAPPITSDPPAHKHAKQILLPPFAPEAVAKLKPRIRAI
HHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHH
CNELIDGFINEKGCDAAARYTRYIPTRAITIMLGVPEKDGDLFIKWIHEILEVGLNDDAA
HHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCHH
VMQAVREMVGYFAEQIEARKKHPTDDLIATLMNARSEDGQPLTDMHVQGALRLLLVAGID
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCH
TAWSAIGSSLWHLAQTPADRERLIAEPELIPTAIEEFLRAFAPATSGREVMKETTVSGCP
HHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCC
MKPGNMVLLSFPAANRDPAVFPDADKIIIDRKENRHIAFGVGIHRCVGAHLARMEMLVAI
CCCCCEEEEECCCCCCCCCCCCCCCEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHH
EEWLKRIPEFRLDPSGGVKWSEGSVRGPRQLPLLLGKA
HHHHHHCCCCEECCCCCCEECCCCCCCCCCCCHHCCCC
>Mature Secondary Structure 
SSPAPVTDWVHDFDHTDPRWTENPYPIWDDLRARCPIAHTNRFLGVYLPTTYEAVKEIS
CCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCHHCCCEEEEECCCHHHHHHHHH
RDTEHFSSRRVVVRNFRPEPPPPAPPITSDPPAHKHAKQILLPPFAPEAVAKLKPRIRAI
HHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHH
CNELIDGFINEKGCDAAARYTRYIPTRAITIMLGVPEKDGDLFIKWIHEILEVGLNDDAA
HHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCHH
VMQAVREMVGYFAEQIEARKKHPTDDLIATLMNARSEDGQPLTDMHVQGALRLLLVAGID
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCH
TAWSAIGSSLWHLAQTPADRERLIAEPELIPTAIEEFLRAFAPATSGREVMKETTVSGCP
HHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCC
MKPGNMVLLSFPAANRDPAVFPDADKIIIDRKENRHIAFGVGIHRCVGAHLARMEMLVAI
CCCCCEEEEECCCCCCCCCCCCCCCEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHH
EEWLKRIPEFRLDPSGGVKWSEGSVRGPRQLPLLLGKA
HHHHHHCCCCEECCCCCCEECCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]