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The map label for this gene is argK [C]

Identifier: 75676425

GI number: 75676425

Start: 2435994

End: 2436974

Strand: Direct

Name: argK [C]

Synonym: Nwi_2240

Alternate gene names: 75676425

Gene position: 2435994-2436974 (Clockwise)

Preceding gene: 75676424

Following gene: 75676426

Centisome position: 71.6

GC content: 67.79

Gene sequence:

>981_bases
ATGAACCGCCCGCTCGCTATCCCCGGCATCGCCGCCGATATCCGCGCCGGCAACCGCGCGGCGCTGGCGCGCGCCATCAC
CCTGATCGAAAGCCGCCGCGCCGATCACGAGGCTACCGCGCGCGAACTGGTGCAGGAGCTTCTGCCGGCGACCGGCAACG
CCATCCGCGTCGGCATCACCGGCTCGCCGGGTGTCGGCAAGTCCACCACCATCGATGCACTCGGCATGGACCTGATCGCG
CGTGGCCACAGGATCGCGGTGCTGGCGGTTGATCCTTCCTCGGTGCGCAGCGGCGGCTCGATCCTCGGCGACAAGACGCG
GATGGCGAGGCTGGCGGCGGCGGAAGCCGCCTACATCCGGCCCTCGCCCGCCGCCGGAACGCTCGGGGGCGTCGCGGCCA
GAACCCGCGAGGCGATGCTGTTGTGCGAAGCGGCGGGCTTCGACGTGATCCTGGTGGAAACCGTGGGAACGGGACAGTCG
GAAACCGCCGTGTACGACATGACGGATTTCTTCCTCGCCTTGATGCTGCCCGGCGCGGGCGACGAACTGCAAGGCATCAA
GAAAGGTCTGGTCGAACTCGCCGACATGATCGCGGTCAACAAGGCTGACGGCGATAATCTGTCACGCGCCAACACCGCCG
CCGCGGCCTATCGCTCCGCGATGAAAATTCTCGTCCCCCGCTCGCAGCACTGGTCTCCGCCGGTGCTGACCTACTCAGGG
CTGACCGGATCAGGCATCCCGGAGCTGTGGCGGAAGATCGTCGAGCACCGCGCCGCGATGAACAGATCCGGCGAGTTCGC
GCAGCGGCGCAGCCGGCAGCAGGTGAAGTGGATGTGGTCGATGTTCGAGGATCGCATCAAGGCGCGCCTGCGCAACGATC
CAGTGATCCGCGAGAAAGTGAAGGCGACCGAGGCCGCGGTTTCCGAGGGCCGCGTCACGCCGGCGCTGGGAGCAAGCCAG
ATCGCGGAACTGCTGCGGTGA

Upstream 100 bases:

>100_bases
CCGTGTTCGTGCCGTGGGAGACCTTCAAGGCGCATCTGTCGCCGCAGGGCCTTGCGATCTTCGGCGGCGACCGCCCTCCC
GATACGAAGCCTGACGCCGA

Downstream 100 bases:

>100_bases
ATTGCGCTGTTTCCACGATCGTCATACTCGGCCGTAGCAGTTCGAAGAACGGCGGCGTTTCGCTCGCCTGTGTGCCGGGC
ATCCACGTCTTCCCTAGTGG

Product: arginine/ornithine transport system ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MNRPLAIPGIAADIRAGNRAALARAITLIESRRADHEATARELVQELLPATGNAIRVGITGSPGVGKSTTIDALGMDLIA
RGHRIAVLAVDPSSVRSGGSILGDKTRMARLAAAEAAYIRPSPAAGTLGGVAARTREAMLLCEAAGFDVILVETVGTGQS
ETAVYDMTDFFLALMLPGAGDELQGIKKGLVELADMIAVNKADGDNLSRANTAAAAYRSAMKILVPRSQHWSPPVLTYSG
LTGSGIPELWRKIVEHRAAMNRSGEFAQRRSRQQVKWMWSMFEDRIKARLRNDPVIREKVKATEAAVSEGRVTPALGASQ
IAELLR

Sequences:

>Translated_326_residues
MNRPLAIPGIAADIRAGNRAALARAITLIESRRADHEATARELVQELLPATGNAIRVGITGSPGVGKSTTIDALGMDLIA
RGHRIAVLAVDPSSVRSGGSILGDKTRMARLAAAEAAYIRPSPAAGTLGGVAARTREAMLLCEAAGFDVILVETVGTGQS
ETAVYDMTDFFLALMLPGAGDELQGIKKGLVELADMIAVNKADGDNLSRANTAAAAYRSAMKILVPRSQHWSPPVLTYSG
LTGSGIPELWRKIVEHRAAMNRSGEFAQRRSRQQVKWMWSMFEDRIKARLRNDPVIREKVKATEAAVSEGRVTPALGASQ
IAELLR
>Mature_326_residues
MNRPLAIPGIAADIRAGNRAALARAITLIESRRADHEATARELVQELLPATGNAIRVGITGSPGVGKSTTIDALGMDLIA
RGHRIAVLAVDPSSVRSGGSILGDKTRMARLAAAEAAYIRPSPAAGTLGGVAARTREAMLLCEAAGFDVILVETVGTGQS
ETAVYDMTDFFLALMLPGAGDELQGIKKGLVELADMIAVNKADGDNLSRANTAAAAYRSAMKILVPRSQHWSPPVLTYSG
LTGSGIPELWRKIVEHRAAMNRSGEFAQRRSRQQVKWMWSMFEDRIKARLRNDPVIREKVKATEAAVSEGRVTPALGASQ
IAELLR

Specific function: May have GTPase activity. May also bind and hydrolyze ATP. May function as chaperone [H]

COG id: COG1703

COG function: function code E; Putative periplasmic protein kinase ArgK and related GTPases of G3E family

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgK family [H]

Homologues:

Organism=Homo sapiens, GI26892295, Length=312, Percent_Identity=48.3974358974359, Blast_Score=296, Evalue=1e-80,
Organism=Escherichia coli, GI1789285, Length=313, Percent_Identity=48.2428115015974, Blast_Score=306, Evalue=1e-84,
Organism=Caenorhabditis elegans, GI71994271, Length=316, Percent_Identity=42.0886075949367, Blast_Score=256, Evalue=9e-69,
Organism=Caenorhabditis elegans, GI71994275, Length=268, Percent_Identity=43.6567164179104, Blast_Score=241, Evalue=5e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005129
- InterPro:   IPR003593 [H]

Pfam domain/function: PF03308 ArgK [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 34740; Mature: 34740

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRPLAIPGIAADIRAGNRAALARAITLIESRRADHEATARELVQELLPATGNAIRVGIT
CCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEEC
GSPGVGKSTTIDALGMDLIARGHRIAVLAVDPSSVRSGGSILGDKTRMARLAAAEAAYIR
CCCCCCCCCHHHHHHHHHHHCCCEEEEEEECHHHHCCCCCCCCCHHHHHHHHHHHHHEEC
PSPAAGTLGGVAARTREAMLLCEAAGFDVILVETVGTGQSETAVYDMTDFFLALMLPGAG
CCCCCCCHHHHHHHHHHHHEEEECCCCCEEEEEECCCCCCCCEEHHHHHHHHHHHCCCCC
DELQGIKKGLVELADMIAVNKADGDNLSRANTAAAAYRSAMKILVPRSQHWSPPVLTYSG
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECC
LTGSGIPELWRKIVEHRAAMNRSGEFAQRRSRQQVKWMWSMFEDRIKARLRNDPVIREKV
CCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
KATEAAVSEGRVTPALGASQIAELLR
HHHHHHHHCCCCCCCCCHHHHHHHHC
>Mature Secondary Structure
MNRPLAIPGIAADIRAGNRAALARAITLIESRRADHEATARELVQELLPATGNAIRVGIT
CCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEEC
GSPGVGKSTTIDALGMDLIARGHRIAVLAVDPSSVRSGGSILGDKTRMARLAAAEAAYIR
CCCCCCCCCHHHHHHHHHHHCCCEEEEEEECHHHHCCCCCCCCCHHHHHHHHHHHHHEEC
PSPAAGTLGGVAARTREAMLLCEAAGFDVILVETVGTGQSETAVYDMTDFFLALMLPGAG
CCCCCCCHHHHHHHHHHHHEEEECCCCCEEEEEECCCCCCCCEEHHHHHHHHHHHCCCCC
DELQGIKKGLVELADMIAVNKADGDNLSRANTAAAAYRSAMKILVPRSQHWSPPVLTYSG
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECC
LTGSGIPELWRKIVEHRAAMNRSGEFAQRRSRQQVKWMWSMFEDRIKARLRNDPVIREKV
CCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
KATEAAVSEGRVTPALGASQIAELLR
HHHHHHHHCCCCCCCCCHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Arg [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8421698; 11259647 [H]