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The map label for this gene is pcp [H]

Identifier: 75676426

GI number: 75676426

Start: 2437120

End: 2437761

Strand: Direct

Name: pcp [H]

Synonym: Nwi_2241

Alternate gene names: 75676426

Gene position: 2437120-2437761 (Clockwise)

Preceding gene: 75676425

Following gene: 75676427

Centisome position: 71.64

GC content: 66.82

Gene sequence:

>642_bases
ATGACGACGTCCCTTCGTGTCCTCATCACCGGCTTCGGCCCGTTTCCCGGCGCGCCGTTCAATCCGACTGTTCCGCTGGT
GAAGCAACTCGCGAGATTGCGCCGGCCCGCGCTGGACGACGTTACGATCACAACCCACATCTTCGATGTCGCGTATGCGA
CGGTGGATTCTGAACTGCCGCGGCTTCTTGCGACGCATCGTCCGCACGCGCTCCTGATGTTCGGTCTCGCGGCGCGCACC
CGCTGGCTGCGGATCGAGACGCGCGCGCGAAACGCAATGACGACGATCTGGCCGGACCAGCACGGGGCGCGGATTCGCAA
GGGCGCGATCGCGGGCACGGCGAATGCGCGTGCGTTCGGGCCGCATGTTTTCAAGCTGCTGCACGCGGCACGCCGGACGG
GCATCGACGCCCGCGCCTCCCGCGATGCCGGCAGCTACCTTTGCAATTATCTCTGCTGGCGCGCCGTCGAGGCCGCCGAT
CATCAGGCAGGGCCGCGGCTCGCCGCGTTCATTCATGTTCCGGCGCTGAAACGCGACGGCTCGGCTGCCGTTCCCGGCGG
CATGACGCTGGCGCATCTCGTCGATGCCGGCGAGGCCATGCTCATGGAAATGGTGAAAGCGGCGCGGCAGACGAGGCTAT
AG

Upstream 100 bases:

>100_bases
AGAACGGCGGCGTTTCGCTCGCCTGTGTGCCGGGCATCCACGTCTTCCCTAGTGGCAGACTTCCAAAGGCAAGACGTGGA
TGGCCGGGACAAGCCCGGCC

Downstream 100 bases:

>100_bases
AGCTTTCAGGCGAAGCATGTCCTTGGGGTCGACCCGGAATCCGGTTCGCGTGACAAGACCGTCAAATCAAATGGACAGCC
ATATTCGAAACGGGCACTGT

Product: peptidase C15, pyroglutamyl peptidase I

Products: NA

Alternate protein names: 5-oxoprolyl-peptidase; Pyroglutamyl-peptidase I; PGP-I; Pyrase [H]

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MTTSLRVLITGFGPFPGAPFNPTVPLVKQLARLRRPALDDVTITTHIFDVAYATVDSELPRLLATHRPHALLMFGLAART
RWLRIETRARNAMTTIWPDQHGARIRKGAIAGTANARAFGPHVFKLLHAARRTGIDARASRDAGSYLCNYLCWRAVEAAD
HQAGPRLAAFIHVPALKRDGSAAVPGGMTLAHLVDAGEAMLMEMVKAARQTRL

Sequences:

>Translated_213_residues
MTTSLRVLITGFGPFPGAPFNPTVPLVKQLARLRRPALDDVTITTHIFDVAYATVDSELPRLLATHRPHALLMFGLAART
RWLRIETRARNAMTTIWPDQHGARIRKGAIAGTANARAFGPHVFKLLHAARRTGIDARASRDAGSYLCNYLCWRAVEAAD
HQAGPRLAAFIHVPALKRDGSAAVPGGMTLAHLVDAGEAMLMEMVKAARQTRL
>Mature_212_residues
TTSLRVLITGFGPFPGAPFNPTVPLVKQLARLRRPALDDVTITTHIFDVAYATVDSELPRLLATHRPHALLMFGLAARTR
WLRIETRARNAMTTIWPDQHGARIRKGAIAGTANARAFGPHVFKLLHAARRTGIDARASRDAGSYLCNYLCWRAVEAADH
QAGPRLAAFIHVPALKRDGSAAVPGGMTLAHLVDAGEAMLMEMVKAARQTRL

Specific function: Removes 5-oxoproline from various penultimate amino acid residues except L-proline [H]

COG id: COG2039

COG function: function code O; Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C15 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000816
- InterPro:   IPR016125 [H]

Pfam domain/function: PF01470 Peptidase_C15 [H]

EC number: =3.4.19.3 [H]

Molecular weight: Translated: 23243; Mature: 23112

Theoretical pI: Translated: 11.63; Mature: 11.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSLRVLITGFGPFPGAPFNPTVPLVKQLARLRRPALDDVTITTHIFDVAYATVDSELP
CCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHH
RLLATHRPHALLMFGLAARTRWLRIETRARNAMTTIWPDQHGARIRKGAIAGTANARAFG
HHHHCCCCHHHHHHHHHHHHHEEEEEHHHCCCEEEECCCCCCCHHHHCCCCCCCCCCCCC
PHVFKLLHAARRTGIDARASRDAGSYLCNYLCWRAVEAADHQAGPRLAAFIHVPALKRDG
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCC
SAAVPGGMTLAHLVDAGEAMLMEMVKAARQTRL
CCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTSLRVLITGFGPFPGAPFNPTVPLVKQLARLRRPALDDVTITTHIFDVAYATVDSELP
CCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHH
RLLATHRPHALLMFGLAARTRWLRIETRARNAMTTIWPDQHGARIRKGAIAGTANARAFG
HHHHCCCCHHHHHHHHHHHHHEEEEEHHHCCCEEEECCCCCCCHHHHCCCCCCCCCCCCC
PHVFKLLHAARRTGIDARASRDAGSYLCNYLCWRAVEAADHQAGPRLAAFIHVPALKRDG
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCC
SAAVPGGMTLAHLVDAGEAMLMEMVKAARQTRL
CCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9756623; 11389725; 11432786 [H]