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The map label for this gene is folB [H]

Identifier: 75676419

GI number: 75676419

Start: 2429523

End: 2429888

Strand: Direct

Name: folB [H]

Synonym: Nwi_2234

Alternate gene names: 75676419

Gene position: 2429523-2429888 (Clockwise)

Preceding gene: 75676418

Following gene: 75676420

Centisome position: 71.41

GC content: 64.48

Gene sequence:

>366_bases
ATGACCGATACGATTTTTATCCGCGGCCTCGTGATTCACGCGCAGCACGGCGTCATGGCGCACGAGACCGAAGTCGGCCA
GCGCTTCGTGATGGACATCGAACTGTCGACCGACCTGTCCGAATCCTCCCGCACCGATCGGCTCGCCGATACGGTATCGT
ATGCGGGCGTGGTGGCGACGGCCAGCGCCGCTTTCAAGGACGCCAACTACAAGCTGCTCGAACGCGCCGCGGGAGCGGTC
GCCGATGCGGTGCTGGCGGCTTATCCGCGCGTGAGGACGATCACGATCACCGTGCACAAGCCGCACGCGCCGATCCCGGC
GATCTTCGACGACGTCGGCATTTCACTTACCCGCGGCAGGGACTAG

Upstream 100 bases:

>100_bases
GCGCGCGCATCATCCGCACACACGATGTGGCCGAGACGGTGCAGGCGCTGCGGGTGGCGCACGCCATCGAGACCGCAACA
CAGCCGGGATCTTTTGAACC

Downstream 100 bases:

>100_bases
CCTTCGCGATGGCCAGCGTCCTGATCGCGCTCGGGGGTAACGTCGGAGACGTCAGGCAGACGTTCCGCAAGGCCATCGCC
AACATCCGCGGCATGGCGCA

Product: dihydroneopterin aldolase

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 121; Mature: 120

Protein sequence:

>121_residues
MTDTIFIRGLVIHAQHGVMAHETEVGQRFVMDIELSTDLSESSRTDRLADTVSYAGVVATASAAFKDANYKLLERAAGAV
ADAVLAAYPRVRTITITVHKPHAPIPAIFDDVGISLTRGRD

Sequences:

>Translated_121_residues
MTDTIFIRGLVIHAQHGVMAHETEVGQRFVMDIELSTDLSESSRTDRLADTVSYAGVVATASAAFKDANYKLLERAAGAV
ADAVLAAYPRVRTITITVHKPHAPIPAIFDDVGISLTRGRD
>Mature_120_residues
TDTIFIRGLVIHAQHGVMAHETEVGQRFVMDIELSTDLSESSRTDRLADTVSYAGVVATASAAFKDANYKLLERAAGAVA
DAVLAAYPRVRTITITVHKPHAPIPAIFDDVGISLTRGRD

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin [H]

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

Organism=Escherichia coli, GI87082204, Length=121, Percent_Identity=33.8842975206612, Blast_Score=64, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 13035; Mature: 12904

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTIFIRGLVIHAQHGVMAHETEVGQRFVMDIELSTDLSESSRTDRLADTVSYAGVVAT
CCCEEEEEEEEEEECCCCEEEHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
ASAAFKDANYKLLERAAGAVADAVLAAYPRVRTITITVHKPHAPIPAIFDDVGISLTRGR
HHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCHHHCCCEEEECCC
D
C
>Mature Secondary Structure 
TDTIFIRGLVIHAQHGVMAHETEVGQRFVMDIELSTDLSESSRTDRLADTVSYAGVVAT
CCEEEEEEEEEEECCCCEEEHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
ASAAFKDANYKLLERAAGAVADAVLAAYPRVRTITITVHKPHAPIPAIFDDVGISLTRGR
HHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCHHHCCCEEEECCC
D
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9168622 [H]