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The map label for this gene is alr [H]

Identifier: 75676204

GI number: 75676204

Start: 2204009

End: 2205196

Strand: Direct

Name: alr [H]

Synonym: Nwi_2014

Alternate gene names: 75676204

Gene position: 2204009-2205196 (Clockwise)

Preceding gene: 75676203

Following gene: 75676205

Centisome position: 64.78

GC content: 65.49

Gene sequence:

>1188_bases
ATGAATCTCGTGCCCGATTCTAAAGTGAGCGGCGAGCCGGCCGATGCCGGCGCGGCTATTGCGGCAGCCGCGGCAATCGG
CACCCTCACGGTCGATCTCGACGCTATCGTCGCCAACTGGCGCAAGCTGGAAAAAACCGCCGTGCCCGCCGAGTGCGCGG
GGGTGATCAAGGCTGACGCTTACGGCTGTGGCGCCCGGCCCGTGGCGCGCGCGCTGAGCGCCGCCGGATGCAGGACGTTT
TTTGTCGCCACGCTCGATGAGGCGCGGGTGGTTCGCGCCGCCGCTTCCACCGCCGACATCTATGTACTGGACGGATTCTT
TCAGAATTGCGGTGACGCCTTCGCGACAATCAATTGCCGGCCCGTGATCGGCGATCTCAATGAACTTGCGGAATGGGACG
TATTTTGCCGGCGCACCGGCTGGGCGGGTGGCGCGGCCATCCACATCGACACCGGAATGAACCGCCTGGGTCTCACCCTG
GATGAGGCGCAAGGCATCCTTCCAAGGATCAATGCCGGCGATCATGGTGTCACGCTGGTGATGAGTCACCTGGCCTGCGC
GGAAAGCCTCCACCATCCGCTCAACGCTAGTCAGGTCGCGGCGTTTCGGGAGATCGCCAGGCAGTTTTCCGGGGTTCCGG
CCTCATTGGCGAACTCGTCCGGCATTTTTCTCGGGGCCCAGTATCAGTTCGACCTGGTGCGTCCGGGCGCCGCGCTCTAT
GGCGTCAACCCCACGCCGGAAGCCGCCAATCCGATGCAGCCGGTCATCGAATTGAAGGCACGGATCATCCAGACCCGCTC
GATCGACAGAGGCGAAAGCGTCGGCTACGGCGCGACCTGGACCGCGCGGCGGCCGACGCGGCTTGCCGTCGTCTCGGCGG
GATACGCCGACGGCTATTTCCGCGCCGGCGGTAGCAATGACGGCACGCGCGGAGCCGAGGTCGTTGTCGCCGGAACGCGA
TGCCCGGTGGCGGGCCGAATTTCCATGGACCTGCTGGCGGTCGACATCACCGACCTGCCGGCCCATGCCGGAGTCCGGCG
TGGTCATCTGGCGACGCTGATCGGCGAGGGCATCACCGTGGACGAACTTGCCCACCATTTCGGCACCATTGGTTACGAGG
TACTCACCAGCCTCGGCGGCCGCTACCACCGGATCTATAAAGGCGGCCCGGCCGAGCCTCGAACCTGA

Upstream 100 bases:

>100_bases
GCACATGAAGGCCACCTGCCGGAGCGGATCTAGCTTACAGACCTTCCAGGCAGACCGCTCGCGCGGTTGAACCGCCGTGC
AGCCGGGCGTAGCATGTAGC

Downstream 100 bases:

>100_bases
CACCCGATCAATGGCTAAATCCGCCCTCTCCTTCGTCTGCCAGAACTGCGGCGCGGCCTATAACCGCTGGCAGGGAAAGT
GTGACGGCTGCGGCGAATGG

Product: alanine racemase region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MNLVPDSKVSGEPADAGAAIAAAAAIGTLTVDLDAIVANWRKLEKTAVPAECAGVIKADAYGCGARPVARALSAAGCRTF
FVATLDEARVVRAAASTADIYVLDGFFQNCGDAFATINCRPVIGDLNELAEWDVFCRRTGWAGGAAIHIDTGMNRLGLTL
DEAQGILPRINAGDHGVTLVMSHLACAESLHHPLNASQVAAFREIARQFSGVPASLANSSGIFLGAQYQFDLVRPGAALY
GVNPTPEAANPMQPVIELKARIIQTRSIDRGESVGYGATWTARRPTRLAVVSAGYADGYFRAGGSNDGTRGAEVVVAGTR
CPVAGRISMDLLAVDITDLPAHAGVRRGHLATLIGEGITVDELAHHFGTIGYEVLTSLGGRYHRIYKGGPAEPRT

Sequences:

>Translated_395_residues
MNLVPDSKVSGEPADAGAAIAAAAAIGTLTVDLDAIVANWRKLEKTAVPAECAGVIKADAYGCGARPVARALSAAGCRTF
FVATLDEARVVRAAASTADIYVLDGFFQNCGDAFATINCRPVIGDLNELAEWDVFCRRTGWAGGAAIHIDTGMNRLGLTL
DEAQGILPRINAGDHGVTLVMSHLACAESLHHPLNASQVAAFREIARQFSGVPASLANSSGIFLGAQYQFDLVRPGAALY
GVNPTPEAANPMQPVIELKARIIQTRSIDRGESVGYGATWTARRPTRLAVVSAGYADGYFRAGGSNDGTRGAEVVVAGTR
CPVAGRISMDLLAVDITDLPAHAGVRRGHLATLIGEGITVDELAHHFGTIGYEVLTSLGGRYHRIYKGGPAEPRT
>Mature_395_residues
MNLVPDSKVSGEPADAGAAIAAAAAIGTLTVDLDAIVANWRKLEKTAVPAECAGVIKADAYGCGARPVARALSAAGCRTF
FVATLDEARVVRAAASTADIYVLDGFFQNCGDAFATINCRPVIGDLNELAEWDVFCRRTGWAGGAAIHIDTGMNRLGLTL
DEAQGILPRINAGDHGVTLVMSHLACAESLHHPLNASQVAAFREIARQFSGVPASLANSSGIFLGAQYQFDLVRPGAALY
GVNPTPEAANPMQPVIELKARIIQTRSIDRGESVGYGATWTARRPTRLAVVSAGYADGYFRAGGSNDGTRGAEVVVAGTR
CPVAGRISMDLLAVDITDLPAHAGVRRGHLATLIGEGITVDELAHHFGTIGYEVLTSLGGRYHRIYKGGPAEPRT

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=371, Percent_Identity=33.6927223719677, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1787439, Length=368, Percent_Identity=33.4239130434783, Blast_Score=155, Evalue=6e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 41331; Mature: 41331

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLVPDSKVSGEPADAGAAIAAAAAIGTLTVDLDAIVANWRKLEKTAVPAECAGVIKADA
CCCCCCCCCCCCCCCCCHHHHHHHHHHEEEEEHHHHHHHHHHHHHHCCCHHHHHEEEECC
YGCGARPVARALSAAGCRTFFVATLDEARVVRAAASTADIYVLDGFFQNCGDAFATINCR
CCCCCHHHHHHHHHCCCCEEEEEECCHHHHHHHHCCCCEEEEECHHHHHCCCCEEEEEEE
PVIGDLNELAEWDVFCRRTGWAGGAAIHIDTGMNRLGLTLDEAQGILPRINAGDHGVTLV
ECCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHCCCHHHHCCCCCCCCCCCCHHHHH
MSHLACAESLHHPLNASQVAAFREIARQFSGVPASLANSSGIFLGAQYQFDLVRPGAALY
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHCCCCCEEEEEEEEEEEECCCCEEE
GVNPTPEAANPMQPVIELKARIIQTRSIDRGESVGYGATWTARRPTRLAVVSAGYADGYF
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCEEEEEECCCCCCEE
RAGGSNDGTRGAEVVVAGTRCPVAGRISMDLLAVDITDLPAHAGVRRGHLATLIGEGITV
ECCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCHHHHHCCCCCH
DELAHHFGTIGYEVLTSLGGRYHRIYKGGPAEPRT
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCC
>Mature Secondary Structure
MNLVPDSKVSGEPADAGAAIAAAAAIGTLTVDLDAIVANWRKLEKTAVPAECAGVIKADA
CCCCCCCCCCCCCCCCCHHHHHHHHHHEEEEEHHHHHHHHHHHHHHCCCHHHHHEEEECC
YGCGARPVARALSAAGCRTFFVATLDEARVVRAAASTADIYVLDGFFQNCGDAFATINCR
CCCCCHHHHHHHHHCCCCEEEEEECCHHHHHHHHCCCCEEEEECHHHHHCCCCEEEEEEE
PVIGDLNELAEWDVFCRRTGWAGGAAIHIDTGMNRLGLTLDEAQGILPRINAGDHGVTLV
ECCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHCCCHHHHCCCCCCCCCCCCHHHHH
MSHLACAESLHHPLNASQVAAFREIARQFSGVPASLANSSGIFLGAQYQFDLVRPGAALY
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHCCCCCEEEEEEEEEEEECCCCEEE
GVNPTPEAANPMQPVIELKARIIQTRSIDRGESVGYGATWTARRPTRLAVVSAGYADGYF
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCEEEEEECCCCCCEE
RAGGSNDGTRGAEVVVAGTRCPVAGRISMDLLAVDITDLPAHAGVRRGHLATLIGEGITV
ECCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCHHHHHCCCCCH
DELAHHFGTIGYEVLTSLGGRYHRIYKGGPAEPRT
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA