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The map label for this gene is hup1 [H]

Identifier: 75676083

GI number: 75676083

Start: 2073631

End: 2073930

Strand: Direct

Name: hup1 [H]

Synonym: Nwi_1892

Alternate gene names: 75676083

Gene position: 2073631-2073930 (Clockwise)

Preceding gene: 75676080

Following gene: 75676084

Centisome position: 60.95

GC content: 62.0

Gene sequence:

>300_bases
ATGGCGAAGAAGGCAGCGACCCCGAGCACCGTGACGCTCAAGCATCTCGCGGCGGCCCTGGCCGAGGACCATGAATTGTC
GAAGAAGGCCGCCGAGGCGATCCTGAGCGACATGGTCACGCGCATCACCAAGCATCTCAAGAAGGGTGATCGTATCCGCA
TTGTCGGCCTCGGCATTCTCCAGGTCCGCAAGCGCGCCGCCCGCAAGGGGCGTAATCCGGCCACTGGCGAGGAAATCCAG
ATCAAGGCTTCCAAGAAGGTCGCGTTCCGCGCCGCCAAAGAACTCAAGGAAGCCATCTGA

Upstream 100 bases:

>100_bases
TGTTTACAGGCAAAATGGCGGGGTCGGCACCTCCCCGAATCAAACAAGGGCTGATACGCCTTGCTTTCCGTAAAACGGCA
ACGACGAGGAGAGCCATATC

Downstream 100 bases:

>100_bases
CCAGAATGCCGGGTCTAAAACACTCCGTTCAATCGCTGGAGGATTGGCCCGCATTCAACCGATAGCCCACGCAAGGCCGG
GATCACTCACCTGGCGAGGT

Product: histone-like DNA-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 99; Mature: 98

Protein sequence:

>99_residues
MAKKAATPSTVTLKHLAAALAEDHELSKKAAEAILSDMVTRITKHLKKGDRIRIVGLGILQVRKRAARKGRNPATGEEIQ
IKASKKVAFRAAKELKEAI

Sequences:

>Translated_99_residues
MAKKAATPSTVTLKHLAAALAEDHELSKKAAEAILSDMVTRITKHLKKGDRIRIVGLGILQVRKRAARKGRNPATGEEIQ
IKASKKVAFRAAKELKEAI
>Mature_98_residues
AKKAATPSTVTLKHLAAALAEDHELSKKAAEAILSDMVTRITKHLKKGDRIRIVGLGILQVRKRAARKGRNPATGEEIQI
KASKKVAFRAAKELKEAI

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1786644, Length=80, Percent_Identity=46.25, Blast_Score=75, Evalue=1e-15,
Organism=Escherichia coli, GI1790433, Length=85, Percent_Identity=45.8823529411765, Blast_Score=74, Evalue=2e-15,

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 10764; Mature: 10633

Theoretical pI: Translated: 11.32; Mature: 11.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKAATPSTVTLKHLAAALAEDHELSKKAAEAILSDMVTRITKHLKKGDRIRIVGLGIL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHH
QVRKRAARKGRNPATGEEIQIKASKKVAFRAAKELKEAI
HHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKKAATPSTVTLKHLAAALAEDHELSKKAAEAILSDMVTRITKHLKKGDRIRIVGLGIL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHH
QVRKRAARKGRNPATGEEIQIKASKKVAFRAAKELKEAI
HHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]