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The map label for this gene is ychE [C]

Identifier: 75675994

GI number: 75675994

Start: 1975229

End: 1975852

Strand: Direct

Name: ychE [C]

Synonym: Nwi_1802

Alternate gene names: 75675994

Gene position: 1975229-1975852 (Clockwise)

Preceding gene: 75675992

Following gene: 75676001

Centisome position: 58.06

GC content: 70.35

Gene sequence:

>624_bases
GTGCTGCCGGACTACGCGCTGACGACCTTCGCGACGCTGATGGTGGTGGTCGATCCGATCGGTCTGGCCCCGGTGTTCCT
GTCAATCACCCAGGGCCTGCCGAAGGCCGCCCGGCGCGGCATCGGCTGGCGCGCCTCGGCGATAGCCGCCGCCATCCTGG
TGGCGACGGCGCTCGGCGGGACATGGCTCCTCGCCCGGCTCGGAATCGGCCTCCCCGCGTTTCGCATCTCCGGCGGACTC
CTGCTGTTCGTGGTCGCGTTCGAGATGGTGCTGGGGGTCCGGCCGGCGCGAGAGGCCCAGCAGGCGACCCAGGCGGCGGA
GGAGCACGCGCGAAATATCGCGGCCTTTCCGCTGGCGATCCCGATGATCGCGGGTCCGGGGGCGATCACGGCCACCCTGC
TGCTGGCCGGTCGCGCGGCGGATCAGCCGGTTCAACTGATAGCGCTGATCGCTATCATCATTGCGGTCGCCGCCATTTGC
GGCGTCACCTTCGCGTTGGCGGGGCGCGTGGCCGGCGCGCTCGGCCACACCGGCAACGTCGTGCTGTCGCGATTGCTCGG
CGTCGTATTGGCCGCCCTCGCCGTCCAGTTCGTCATCGATGGCATTCGCGAGGCGTTCGGCTGA

Upstream 100 bases:

>100_bases
TGGGAAAACCACCTTCGGCGATCGCCGGAGGCGGTTTTTTCCCGTCGTTCTTTCAGTTACTTATAAGCCATATTGGCAAC
CAGAATCTGATGGTGGAACG

Downstream 100 bases:

>100_bases
AAAGGGACCGGTAAACGTCGCGTCCGTGCGTCAGGCTGGCCCGAGCGAGAGCCTCGCTTCTGATGAAACGATGCTTTGAC
TTCAAGCGAACGGAAACCTC

Product: multiple antibiotic resistance (MarC)-related proteins

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MLPDYALTTFATLMVVVDPIGLAPVFLSITQGLPKAARRGIGWRASAIAAAILVATALGGTWLLARLGIGLPAFRISGGL
LLFVVAFEMVLGVRPAREAQQATQAAEEHARNIAAFPLAIPMIAGPGAITATLLLAGRAADQPVQLIALIAIIIAVAAIC
GVTFALAGRVAGALGHTGNVVLSRLLGVVLAALAVQFVIDGIREAFG

Sequences:

>Translated_207_residues
MLPDYALTTFATLMVVVDPIGLAPVFLSITQGLPKAARRGIGWRASAIAAAILVATALGGTWLLARLGIGLPAFRISGGL
LLFVVAFEMVLGVRPAREAQQATQAAEEHARNIAAFPLAIPMIAGPGAITATLLLAGRAADQPVQLIALIAIIIAVAAIC
GVTFALAGRVAGALGHTGNVVLSRLLGVVLAALAVQFVIDGIREAFG
>Mature_207_residues
MLPDYALTTFATLMVVVDPIGLAPVFLSITQGLPKAARRGIGWRASAIAAAILVATALGGTWLLARLGIGLPAFRISGGL
LLFVVAFEMVLGVRPAREAQQATQAAEEHARNIAAFPLAIPMIAGPGAITATLLLAGRAADQPVQLIALIAIIIAVAAIC
GVTFALAGRVAGALGHTGNVVLSRLLGVVLAALAVQFVIDGIREAFG

Specific function: Unknown

COG id: COG2095

COG function: function code U; Multiple antibiotic transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0056 (marC) family [H]

Homologues:

Organism=Escherichia coli, GI1787494, Length=206, Percent_Identity=32.5242718446602, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1789842, Length=194, Percent_Identity=30.9278350515464, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787809, Length=197, Percent_Identity=30.4568527918782, Blast_Score=78, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002771 [H]

Pfam domain/function: PF01914 MarC [H]

EC number: NA

Molecular weight: Translated: 21073; Mature: 21073

Theoretical pI: Translated: 11.08; Mature: 11.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPDYALTTFATLMVVVDPIGLAPVFLSITQGLPKAARRGIGWRASAIAAAILVATALGG
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHH
TWLLARLGIGLPAFRISGGLLLFVVAFEMVLGVRPAREAQQATQAAEEHARNIAAFPLAI
HHHHHHHCCCCCHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
PMIAGPGAITATLLLAGRAADQPVQLIALIAIIIAVAAICGVTFALAGRVAGALGHTGNV
HHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VLSRLLGVVLAALAVQFVIDGIREAFG
HHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLPDYALTTFATLMVVVDPIGLAPVFLSITQGLPKAARRGIGWRASAIAAAILVATALGG
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHH
TWLLARLGIGLPAFRISGGLLLFVVAFEMVLGVRPAREAQQATQAAEEHARNIAAFPLAI
HHHHHHHCCCCCHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
PMIAGPGAITATLLLAGRAADQPVQLIALIAIIIAVAAICGVTFALAGRVAGALGHTGNV
HHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VLSRLLGVVLAALAVQFVIDGIREAFG
HHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]