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The map label for this gene is erpA [H]

Identifier: 75676001

GI number: 75676001

Start: 1983329

End: 1983661

Strand: Direct

Name: erpA [H]

Synonym: Nwi_1809

Alternate gene names: 75676001

Gene position: 1983329-1983661 (Clockwise)

Preceding gene: 75675994

Following gene: 75676002

Centisome position: 58.3

GC content: 60.96

Gene sequence:

>333_bases
ATGACAGAAGCCAACATCACCGTCAGCGAGCGCGCGGCGCGGCGGATCAGAGAAATCCTGAAATCCGAGGGCGACGGCGC
CATGTTGCGTATCAGCGTCGAAGGCGGAGGCTGCTCGGGCTTTCAGTACAAATTCGACATCGAACGCGCCAAGGCCGACG
ATGATCTGGTGATCGCGCGAGATTCCGCGGTGGTGCTCGTCGATCCAGCCTCCGTCCCTTTCCTGAGCGGGTCCGAAGTC
GATTTCGTCGACGATCTGATCGGAGCATCGTTCCGGGTCGTCAATCCGAACGCCACCGCCTCCTGCGGCTGCGGCACCAG
CTTTTCGATATAG

Upstream 100 bases:

>100_bases
CCCTTCCGATGGTTTGATTCCGCCGTAAGCCCACTTAACTATGGCTTGCGGGCAATTCAAAATATTGGACAATGTCCGCG
ATCGCATATGGAGTCGCAGG

Downstream 100 bases:

>100_bases
TTTTTCGGGGTCAGAGGCGGCCTTGACCCGCTGAAAGAGACCTCACGGCGGATTGCCCGTTGAGACCGGCAATCACATGC
GGGACCGCCTGATGCGCATA

Product: HesB/YadR/YfhF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 110; Mature: 109

Protein sequence:

>110_residues
MTEANITVSERAARRIREILKSEGDGAMLRISVEGGGCSGFQYKFDIERAKADDDLVIARDSAVVLVDPASVPFLSGSEV
DFVDDLIGASFRVVNPNATASCGCGTSFSI

Sequences:

>Translated_110_residues
MTEANITVSERAARRIREILKSEGDGAMLRISVEGGGCSGFQYKFDIERAKADDDLVIARDSAVVLVDPASVPFLSGSEV
DFVDDLIGASFRVVNPNATASCGCGTSFSI
>Mature_109_residues
TEANITVSERAARRIREILKSEGDGAMLRISVEGGGCSGFQYKFDIERAKADDDLVIARDSAVVLVDPASVPFLSGSEVD
FVDDLIGASFRVVNPNATASCGCGTSFSI

Specific function: Required for insertion of 4Fe-4S clusters for at least ispG [H]

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI160420328, Length=109, Percent_Identity=45.8715596330275, Blast_Score=92, Evalue=8e-20,
Organism=Homo sapiens, GI52426768, Length=109, Percent_Identity=31.1926605504587, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786351, Length=106, Percent_Identity=38.6792452830189, Blast_Score=91, Evalue=2e-20,
Organism=Escherichia coli, GI1788877, Length=106, Percent_Identity=36.7924528301887, Blast_Score=80, Evalue=4e-17,
Organism=Escherichia coli, GI1787974, Length=105, Percent_Identity=36.1904761904762, Blast_Score=79, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71998452, Length=112, Percent_Identity=43.75, Blast_Score=98, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI25146411, Length=110, Percent_Identity=36.3636363636364, Blast_Score=82, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI193209025, Length=107, Percent_Identity=36.4485981308411, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6325324, Length=128, Percent_Identity=34.375, Blast_Score=85, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6323001, Length=107, Percent_Identity=31.7757009345794, Blast_Score=72, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24649697, Length=109, Percent_Identity=47.7064220183486, Blast_Score=102, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24642263, Length=109, Percent_Identity=33.9449541284404, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 11634; Mature: 11503

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEANITVSERAARRIREILKSEGDGAMLRISVEGGGCSGFQYKFDIERAKADDDLVIAR
CCCCCEEHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEEEECCCCCCCEEEEC
DSAVVLVDPASVPFLSGSEVDFVDDLIGASFRVVNPNATASCGCGTSFSI
CCEEEEECCCCCCEECCCCCCHHHHHHCCEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TEANITVSERAARRIREILKSEGDGAMLRISVEGGGCSGFQYKFDIERAKADDDLVIAR
CCCCEEHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEEEECCCCCCCEEEEC
DSAVVLVDPASVPFLSGSEVDFVDDLIGASFRVVNPNATASCGCGTSFSI
CCEEEEECCCCCCEECCCCCCHHHHHHCCEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]