Click here to switch to the map view.

The map label for this gene is ahpC [C]

Identifier: 75675930

GI number: 75675930

Start: 1899699

End: 1900358

Strand: Direct

Name: ahpC [C]

Synonym: Nwi_1738

Alternate gene names: 75675930

Gene position: 1899699-1900358 (Clockwise)

Preceding gene: 75675923

Following gene: 75675931

Centisome position: 55.84

GC content: 60.0

Gene sequence:

>660_bases
ATGACTTTATCGATTGGCTCGACCGCTCCCGATTTCGAAGCTGAAAGCACCGAAGGCCCCATCAGCTTTCACAAGTGGCT
GGGTGATAGCTGGGGGTTGTTCTTTTCGCACCCCAAGGACTTCACGCCGGTCTGCACCACCGAGCTCGGCGCCGTCGCCC
GGCTCAAGCCGGAATTCGACAAGCGGGGCGTCAAGCTGATCGGCATCAGCGTCGACCCGACCGACAAGCATCACCTCTGG
TCCAAGGACATCGAGGAAACGCAGGGCGTCGCGCCGAACTATCCGCTGATCGCGGATGTCGATTTCAAGGTCGCCAAGCT
CTACGGCATGTTGCCGGCCAGCACGTCCGGCGACGTCAACAAGCGGACGCCCGCCGACAATCAGACCGTGCGCAACATCT
TCGTGATCGGCCCAGACAAGCAGGTCAAGATCGTTCTCATTTACCCGATGAGCACCGGCCGCAACTGGCAGGAGGTGCTG
CGCGTGATCGACTCCCTGCAACTCACCGCCAAACACGGCGTTTCGACCCCGTCAGACTGGAAGCAAGGCGACGATGTGTT
CTTTTCCGCCGCGGTTCCGGAGGAAGAGGCCCGCAAGAAATTCCCCAAGGGATGGAAGTCGCCGAAGCCGTATTTTCGGA
TCGTCGAACAGCCGAAGTAA

Upstream 100 bases:

>100_bases
GAAAAAAAGACATTGTCTTTTTCGTAACCGGTTCCGTTTCGCGAGGTCCGAGCCTATAGTCCCCGCCACCAGTTAACTGT
GTGACACGAGGACGTGACTT

Downstream 100 bases:

>100_bases
CGCGGGCAGCTTCAACGCCTGCGCAAGTGAAGGGACGCCTCCAGGGCGTCCCTTTCTTTTTGGCTAGTTAAGCGAAGCAT
GTCCTCGGGGCTTGACCCGA

Product: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MTLSIGSTAPDFEAESTEGPISFHKWLGDSWGLFFSHPKDFTPVCTTELGAVARLKPEFDKRGVKLIGISVDPTDKHHLW
SKDIEETQGVAPNYPLIADVDFKVAKLYGMLPASTSGDVNKRTPADNQTVRNIFVIGPDKQVKIVLIYPMSTGRNWQEVL
RVIDSLQLTAKHGVSTPSDWKQGDDVFFSAAVPEEEARKKFPKGWKSPKPYFRIVEQPK

Sequences:

>Translated_219_residues
MTLSIGSTAPDFEAESTEGPISFHKWLGDSWGLFFSHPKDFTPVCTTELGAVARLKPEFDKRGVKLIGISVDPTDKHHLW
SKDIEETQGVAPNYPLIADVDFKVAKLYGMLPASTSGDVNKRTPADNQTVRNIFVIGPDKQVKIVLIYPMSTGRNWQEVL
RVIDSLQLTAKHGVSTPSDWKQGDDVFFSAAVPEEEARKKFPKGWKSPKPYFRIVEQPK
>Mature_218_residues
TLSIGSTAPDFEAESTEGPISFHKWLGDSWGLFFSHPKDFTPVCTTELGAVARLKPEFDKRGVKLIGISVDPTDKHHLWS
KDIEETQGVAPNYPLIADVDFKVAKLYGMLPASTSGDVNKRTPADNQTVRNIFVIGPDKQVKIVLIYPMSTGRNWQEVLR
VIDSLQLTAKHGVSTPSDWKQGDDVFFSAAVPEEEARKKFPKGWKSPKPYFRIVEQPK

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=225, Percent_Identity=50.2222222222222, Blast_Score=214, Evalue=5e-56,
Organism=Homo sapiens, GI32189392, Length=186, Percent_Identity=31.1827956989247, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI4505591, Length=187, Percent_Identity=32.0855614973262, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI32455266, Length=187, Percent_Identity=32.0855614973262, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI32455264, Length=187, Percent_Identity=32.0855614973262, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI5453549, Length=170, Percent_Identity=27.0588235294118, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI32483377, Length=185, Percent_Identity=25.9459459459459, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI5802974, Length=161, Percent_Identity=26.7080745341615, Blast_Score=71, Evalue=7e-13,
Organism=Escherichia coli, GI1786822, Length=155, Percent_Identity=30.9677419354839, Blast_Score=69, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25153706, Length=229, Percent_Identity=32.7510917030568, Blast_Score=146, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI32565831, Length=201, Percent_Identity=27.363184079602, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI193204376, Length=201, Percent_Identity=27.363184079602, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17554494, Length=153, Percent_Identity=29.4117647058824, Blast_Score=77, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6319407, Length=215, Percent_Identity=48.8372093023256, Blast_Score=207, Evalue=1e-54,
Organism=Saccharomyces cerevisiae, GI6323613, Length=188, Percent_Identity=26.5957446808511, Blast_Score=73, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6320661, Length=164, Percent_Identity=28.0487804878049, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24652434, Length=207, Percent_Identity=46.8599033816425, Blast_Score=187, Evalue=4e-48,
Organism=Drosophila melanogaster, GI17975518, Length=207, Percent_Identity=46.8599033816425, Blast_Score=186, Evalue=7e-48,
Organism=Drosophila melanogaster, GI24652436, Length=207, Percent_Identity=46.3768115942029, Blast_Score=186, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24581278, Length=222, Percent_Identity=44.5945945945946, Blast_Score=183, Evalue=8e-47,
Organism=Drosophila melanogaster, GI21357347, Length=198, Percent_Identity=27.2727272727273, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI17157991, Length=164, Percent_Identity=31.7073170731707, Blast_Score=81, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24641739, Length=164, Percent_Identity=31.7073170731707, Blast_Score=81, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24656348, Length=202, Percent_Identity=28.2178217821782, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI17864676, Length=202, Percent_Identity=28.2178217821782, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI17738015, Length=201, Percent_Identity=28.3582089552239, Blast_Score=78, Evalue=4e-15,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 24471; Mature: 24340

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSIGSTAPDFEAESTEGPISFHKWLGDSWGLFFSHPKDFTPVCTTELGAVARLKPEFD
CEEECCCCCCCCCCCCCCCCCHHHHHCCCCCCEEECCCCCCCCCHHHHHCHHHHCCCCCC
KRGVKLIGISVDPTDKHHLWSKDIEETQGVAPNYPLIADVDFKVAKLYGMLPASTSGDVN
CCCEEEEEEEECCCCCCCCCCCCHHHHCCCCCCCCEEEECCHHHHHHHHCCCCCCCCCCC
KRTPADNQTVRNIFVIGPDKQVKIVLIYPMSTGRNWQEVLRVIDSLQLTAKHGVSTPSDW
CCCCCCCCEEEEEEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
KQGDDVFFSAAVPEEEARKKFPKGWKSPKPYFRIVEQPK
CCCCCEEEEECCCHHHHHHHCCCCCCCCCCCEEEECCCC
>Mature Secondary Structure 
TLSIGSTAPDFEAESTEGPISFHKWLGDSWGLFFSHPKDFTPVCTTELGAVARLKPEFD
EEECCCCCCCCCCCCCCCCCHHHHHCCCCCCEEECCCCCCCCCHHHHHCHHHHCCCCCC
KRGVKLIGISVDPTDKHHLWSKDIEETQGVAPNYPLIADVDFKVAKLYGMLPASTSGDVN
CCCEEEEEEEECCCCCCCCCCCCHHHHCCCCCCCCEEEECCHHHHHHHHCCCCCCCCCCC
KRTPADNQTVRNIFVIGPDKQVKIVLIYPMSTGRNWQEVLRVIDSLQLTAKHGVSTPSDW
CCCCCCCCEEEEEEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
KQGDDVFFSAAVPEEEARKKFPKGWKSPKPYFRIVEQPK
CCCCCEEEEECCCHHHHHHHCCCCCCCCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]