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The map label for this gene is ntrY [H]

Identifier: 75675638

GI number: 75675638

Start: 1575035

End: 1577335

Strand: Direct

Name: ntrY [H]

Synonym: Nwi_1446

Alternate gene names: 75675638

Gene position: 1575035-1577335 (Clockwise)

Preceding gene: 75675637

Following gene: 75675639

Centisome position: 46.3

GC content: 61.41

Gene sequence:

>2301_bases
ATGACCACAGCAGACACGCCGGTTCCCTCGCACGATCCGACATTCGCCGAGTCGCGTGGCTGGGCGATGCGCCGGCTATT
GGCGCCCGTCGCGATCGGCCTTGCGCTGCTGTCGGCATTCCTGACTTTCGTGGTTTTGGTTGGCCTCACGCCGATCGAGC
CGACGCACCGGGTCGTCATTACGTTTCTGCTGGTCGACGCCGGCATCATCCTTCTGCTCGTTGGCATCATCGCCCGCGAG
GTCTGGCGTGTCGTGCAAGCCCGCCGCCGGGGGCGCGCCGCGGCGAAGCTGCATGTGCAGGTCGTCGGTCTTTTCTCGAT
CATCGCCGTTCTGCCGGCGGTCGTGGTGTCGGTCGTCGCCAGCGTCACGATCGATCGCGGCCTTGACCGTCTGTTTTCAG
GGCCGATCAAGGAGGTTATTGAGAACTCGCGGATCGTCGCACACGCTTATGCGAACGAGCATGCCCAACTGATCCGGGGC
GATATCCTGGGCATGGCCAATGACGTTTCCAACGCACGGCCGCTCTACGACCAGGACCGCGTGACATTTCTCCAACTCCT
GACCTCCAGCGCCAAGGCTCGCAACCTTCCCGGCGCGATGCTGATCGATAAGGAGGGTCATCTGCTGGTATCGGCGCAAA
CCGGCATCAAGCGAGCCTACGACACGCCGAACCCCGACATTCTCAAGAATGTGAATGAGGACGATCCGCAGATCGCGCTC
ATTCCGGAGGCGAACTACGTCGCCGCCGTCATTCGCCTTCGCGCGTTTCAGGACACGTTCCTTTACGTCGCGAGATTGCT
CGATCCCTATGTCGTCTCGCAACTGAAGCAGACCGAGTCGAGCATTGTCGAATACGCCACGATCGAGGCTCGGCGTCTTG
GCATCCAGGTGGCGCTCGCGCTGATGTTCGCTGTGATTGCGCTGACCATTCTGATGGCGTCGGTATTGCTAGGCCTCAAC
TTCGCGGACCGGTTCGTGGCCCCCGTCCGACGCCTGATGAACGCGGCCAACCTCGTATCCACCGGCGACCTGAACGTTCA
GGTTCCTGTTTTGAAATCCGAAGGCGACCTGGCGCAGCTCGGCGAGACATTCAACAAGATGACCGCCGAATTGCGCACTC
AGCGCGACGAACTCGTTAATGCGAGCGGCCTGATCGACAGCCGGCGCCGTTTCATCGAGGCGGTGCTGTCGTCGGCCAGC
GCCGGCATCATCGGCGTCGACGGCGCCAACACCATCCGCATCCTGAACCGCTCGGCGGAGAAGCTGATCGGCCATTCGGA
ATCAGAAACGCTCGGACATCCGCTATCCGAGGTCATCCCCGAGCTGAGCGATCTCATGCAGACGGCGAGGGAGGGGGCGC
AACGGCTGGTGCAGGGCCAGATCACGCTCAATCGCGACGGCAATGAGCGTAACATCTCGGTGCGCGTCAGCGCCGAGCAA
ACCAGTCAATCGCGTGACAGCTACATCATCACCCTGGACGATATCACGGAGCTTGTGACCGCGCAGCGTACGTCCGCGTG
GGGCGATGTGGCGCGACGTATCGCTCATGAAATCAAGAATCCGTTGACACCGATCCAGCTTTCGGCCGAGCGCATCCGCC
GTAAATTCGGCAAGGTGATCACTCAGGACAAGCCGATCTTCGAGCAATGCACCGACACCATCGTGCGTCAGGTTGAGGAT
ATCAGGCGGATGGTCGATGAGTTCTCGCGTTTCGCGCGAATGCCGAAGCCCGTGATGGAAGGAGAGGATGTCGCCGATAC
GGTCCGCCAGACGGTTTTCCTCATGCGTGTCGGACATCCCGAGATCGATATCGAAGCCGACATCAGGCAAGAACCGATGC
GCGCGCAGTTTGACCGGCGGCTGATCTCGCAGGCGCTGACCAATATCATCAAGAACGCGGCCGAAGCCATCGAAGCGGTG
CCGCCGGAGGTGCTCGGAAAAGGCCGGATCGACGTCATCGCCGCGCAGGAAGAAGACGACATCATCATTGACGTGATCGA
CAATGGTGTCGGCTTACCGAAAGTTGCGCGCGCGCGGCTGCTGGAGCCTTACGTGACGACACGCGAAAAGGGTACCGGCC
TTGGTCTTGCGATCGTGGGGCGCGTTCTGGAAGACCACGGCGGAAAGCTCGAGCTCAATGACGCGTCGGCGATCAGGCCG
GAAGCGCGGGGAGCCTGGATGCGGTTGCGGTTTGCAGCGACGGGGCCAGCGAATGCGGGAACCATTGGGGATGATGGAGC
GACTAACGGGGATACCCTGACCGGAAAAGAAACAAAGACTGAGGTTGCGACCGGCGGCTGA

Upstream 100 bases:

>100_bases
TGTTCGCGCCGCGGAAATGTCCCAATTGTGCAACATTGTTGTATGATTGCATCAGTTCGCTGGTTGCGCCAGCCAGCTTA
AACGCCCAGCTTTCACGCGG

Downstream 100 bases:

>100_bases
CGAGGCGGATCCAATTCATGGCACATGACATTCTGATTGTTGACGACGAGGCGGACATTCGCGACCTGGTTGCGGGCATC
CTGGAAGATGAGGGGTTCAC

Product: nitrogen regulatory signal transduction histidine kinase NtrY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 766; Mature: 765

Protein sequence:

>766_residues
MTTADTPVPSHDPTFAESRGWAMRRLLAPVAIGLALLSAFLTFVVLVGLTPIEPTHRVVITFLLVDAGIILLLVGIIARE
VWRVVQARRRGRAAAKLHVQVVGLFSIIAVLPAVVVSVVASVTIDRGLDRLFSGPIKEVIENSRIVAHAYANEHAQLIRG
DILGMANDVSNARPLYDQDRVTFLQLLTSSAKARNLPGAMLIDKEGHLLVSAQTGIKRAYDTPNPDILKNVNEDDPQIAL
IPEANYVAAVIRLRAFQDTFLYVARLLDPYVVSQLKQTESSIVEYATIEARRLGIQVALALMFAVIALTILMASVLLGLN
FADRFVAPVRRLMNAANLVSTGDLNVQVPVLKSEGDLAQLGETFNKMTAELRTQRDELVNASGLIDSRRRFIEAVLSSAS
AGIIGVDGANTIRILNRSAEKLIGHSESETLGHPLSEVIPELSDLMQTAREGAQRLVQGQITLNRDGNERNISVRVSAEQ
TSQSRDSYIITLDDITELVTAQRTSAWGDVARRIAHEIKNPLTPIQLSAERIRRKFGKVITQDKPIFEQCTDTIVRQVED
IRRMVDEFSRFARMPKPVMEGEDVADTVRQTVFLMRVGHPEIDIEADIRQEPMRAQFDRRLISQALTNIIKNAAEAIEAV
PPEVLGKGRIDVIAAQEEDDIIIDVIDNGVGLPKVARARLLEPYVTTREKGTGLGLAIVGRVLEDHGGKLELNDASAIRP
EARGAWMRLRFAATGPANAGTIGDDGATNGDTLTGKETKTEVATGG

Sequences:

>Translated_766_residues
MTTADTPVPSHDPTFAESRGWAMRRLLAPVAIGLALLSAFLTFVVLVGLTPIEPTHRVVITFLLVDAGIILLLVGIIARE
VWRVVQARRRGRAAAKLHVQVVGLFSIIAVLPAVVVSVVASVTIDRGLDRLFSGPIKEVIENSRIVAHAYANEHAQLIRG
DILGMANDVSNARPLYDQDRVTFLQLLTSSAKARNLPGAMLIDKEGHLLVSAQTGIKRAYDTPNPDILKNVNEDDPQIAL
IPEANYVAAVIRLRAFQDTFLYVARLLDPYVVSQLKQTESSIVEYATIEARRLGIQVALALMFAVIALTILMASVLLGLN
FADRFVAPVRRLMNAANLVSTGDLNVQVPVLKSEGDLAQLGETFNKMTAELRTQRDELVNASGLIDSRRRFIEAVLSSAS
AGIIGVDGANTIRILNRSAEKLIGHSESETLGHPLSEVIPELSDLMQTAREGAQRLVQGQITLNRDGNERNISVRVSAEQ
TSQSRDSYIITLDDITELVTAQRTSAWGDVARRIAHEIKNPLTPIQLSAERIRRKFGKVITQDKPIFEQCTDTIVRQVED
IRRMVDEFSRFARMPKPVMEGEDVADTVRQTVFLMRVGHPEIDIEADIRQEPMRAQFDRRLISQALTNIIKNAAEAIEAV
PPEVLGKGRIDVIAAQEEDDIIIDVIDNGVGLPKVARARLLEPYVTTREKGTGLGLAIVGRVLEDHGGKLELNDASAIRP
EARGAWMRLRFAATGPANAGTIGDDGATNGDTLTGKETKTEVATGG
>Mature_765_residues
TTADTPVPSHDPTFAESRGWAMRRLLAPVAIGLALLSAFLTFVVLVGLTPIEPTHRVVITFLLVDAGIILLLVGIIAREV
WRVVQARRRGRAAAKLHVQVVGLFSIIAVLPAVVVSVVASVTIDRGLDRLFSGPIKEVIENSRIVAHAYANEHAQLIRGD
ILGMANDVSNARPLYDQDRVTFLQLLTSSAKARNLPGAMLIDKEGHLLVSAQTGIKRAYDTPNPDILKNVNEDDPQIALI
PEANYVAAVIRLRAFQDTFLYVARLLDPYVVSQLKQTESSIVEYATIEARRLGIQVALALMFAVIALTILMASVLLGLNF
ADRFVAPVRRLMNAANLVSTGDLNVQVPVLKSEGDLAQLGETFNKMTAELRTQRDELVNASGLIDSRRRFIEAVLSSASA
GIIGVDGANTIRILNRSAEKLIGHSESETLGHPLSEVIPELSDLMQTAREGAQRLVQGQITLNRDGNERNISVRVSAEQT
SQSRDSYIITLDDITELVTAQRTSAWGDVARRIAHEIKNPLTPIQLSAERIRRKFGKVITQDKPIFEQCTDTIVRQVEDI
RRMVDEFSRFARMPKPVMEGEDVADTVRQTVFLMRVGHPEIDIEADIRQEPMRAQFDRRLISQALTNIIKNAAEAIEAVP
PEVLGKGRIDVIAAQEEDDIIIDVIDNGVGLPKVARARLLEPYVTTREKGTGLGLAIVGRVLEDHGGKLELNDASAIRPE
ARGAWMRLRFAATGPANAGTIGDDGATNGDTLTGKETKTEVATGG

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=388, Percent_Identity=22.9381443298969, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI1790300, Length=340, Percent_Identity=27.6470588235294, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1790436, Length=221, Percent_Identity=25.3393665158371, Blast_Score=74, Evalue=5e-14,
Organism=Escherichia coli, GI1789808, Length=206, Percent_Identity=29.6116504854369, Blast_Score=69, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 83664; Mature: 83532

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTADTPVPSHDPTFAESRGWAMRRLLAPVAIGLALLSAFLTFVVLVGLTPIEPTHRVVI
CCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
TFLLVDAGIILLLVGIIAREVWRVVQARRRGRAAAKLHVQVVGLFSIIAVLPAVVVSVVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVTIDRGLDRLFSGPIKEVIENSRIVAHAYANEHAQLIRGDILGMANDVSNARPLYDQDR
HHHHHHHHHHHHCCHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
VTFLQLLTSSAKARNLPGAMLIDKEGHLLVSAQTGIKRAYDTPNPDILKNVNEDDPQIAL
HHHHHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCHHHCCCCCCHHHHCCCCCCCCEEE
IPEANYVAAVIRLRAFQDTFLYVARLLDPYVVSQLKQTESSIVEYATIEARRLGIQVALA
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMFAVIALTILMASVLLGLNFADRFVAPVRRLMNAANLVSTGDLNVQVPVLKSEGDLAQL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHH
GETFNKMTAELRTQRDELVNASGLIDSRRRFIEAVLSSASAGIIGVDGANTIRILNRSAE
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHH
KLIGHSESETLGHPLSEVIPELSDLMQTAREGAQRLVQGQITLNRDGNERNISVRVSAEQ
HHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCEEEEEEECHH
TSQSRDSYIITLDDITELVTAQRTSAWGDVARRIAHEIKNPLTPIQLSAERIRRKFGKVI
CCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
TQDKPIFEQCTDTIVRQVEDIRRMVDEFSRFARMPKPVMEGEDVADTVRQTVFLMRVGHP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCC
EIDIEADIRQEPMRAQFDRRLISQALTNIIKNAAEAIEAVPPEVLGKGRIDVIAAQEEDD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEEECCCCC
IIIDVIDNGVGLPKVARARLLEPYVTTREKGTGLGLAIVGRVLEDHGGKLELNDASAIRP
EEEEEECCCCCCHHHHHHHHHCHHHHCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCC
EARGAWMRLRFAATGPANAGTIGDDGATNGDTLTGKETKTEVATGG
CCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TTADTPVPSHDPTFAESRGWAMRRLLAPVAIGLALLSAFLTFVVLVGLTPIEPTHRVVI
CCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
TFLLVDAGIILLLVGIIAREVWRVVQARRRGRAAAKLHVQVVGLFSIIAVLPAVVVSVVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVTIDRGLDRLFSGPIKEVIENSRIVAHAYANEHAQLIRGDILGMANDVSNARPLYDQDR
HHHHHHHHHHHHCCHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
VTFLQLLTSSAKARNLPGAMLIDKEGHLLVSAQTGIKRAYDTPNPDILKNVNEDDPQIAL
HHHHHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCHHHCCCCCCHHHHCCCCCCCCEEE
IPEANYVAAVIRLRAFQDTFLYVARLLDPYVVSQLKQTESSIVEYATIEARRLGIQVALA
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMFAVIALTILMASVLLGLNFADRFVAPVRRLMNAANLVSTGDLNVQVPVLKSEGDLAQL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHH
GETFNKMTAELRTQRDELVNASGLIDSRRRFIEAVLSSASAGIIGVDGANTIRILNRSAE
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHH
KLIGHSESETLGHPLSEVIPELSDLMQTAREGAQRLVQGQITLNRDGNERNISVRVSAEQ
HHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCEEEEEEECHH
TSQSRDSYIITLDDITELVTAQRTSAWGDVARRIAHEIKNPLTPIQLSAERIRRKFGKVI
CCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
TQDKPIFEQCTDTIVRQVEDIRRMVDEFSRFARMPKPVMEGEDVADTVRQTVFLMRVGHP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCC
EIDIEADIRQEPMRAQFDRRLISQALTNIIKNAAEAIEAVPPEVLGKGRIDVIAAQEEDD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEEECCCCC
IIIDVIDNGVGLPKVARARLLEPYVTTREKGTGLGLAIVGRVLEDHGGKLELNDASAIRP
EEEEEECCCCCCHHHHHHHHHCHHHHCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCC
EARGAWMRLRFAATGPANAGTIGDDGATNGDTLTGKETKTEVATGG
CCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]