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The map label for this gene is ctaA

Identifier: 75675610

GI number: 75675610

Start: 1544240

End: 1545322

Strand: Direct

Name: ctaA

Synonym: Nwi_1418

Alternate gene names: 75675610

Gene position: 1544240-1545322 (Clockwise)

Preceding gene: 75675607

Following gene: 75675611

Centisome position: 45.39

GC content: 61.96

Gene sequence:

>1083_bases
ATGACCCGTCCGATTGCACAAAAGGAATCCCATCTGCGCGCCGTGCGCTGGTGGCTGGTGTTCATGGCGCTGCTGATTGC
CGCCATGGTGCTGGTCGGCGGAGCGACGCGGCTGACTGAATCCGGCCTTTCGATCGTCGAGTGGAAACCCGTGACGGGCT
CGCTTCCTCCGCTTTCTCAGGCGGAATGGATTCAGGCTTTTGAGGGCTACAAAGCGATACCGCAGTATCGCGAGATGAAC
GCGGGCATGACGCTCGATCAGTTCAAGACCATCTTCTGGTGGGAGTGGAGCCATCGCCTGCTCGGACGCTTCATCGGTAT
CGCGTTCCTGTTGCCGTTCCTCTGGTTCATGTGGCGCGGCGCGCTGCCGTCGGATCTGAAGCGGCGGCTCTGGATTATTT
TCGGCCTGGGTGGCCTTCAGGGCGCGGTCGGCTGGTGGATGGTCGCCTCCGGTCTTACCGAGCGCACCGAGGTGTCGCAG
TATCGTCTGGCGACGCATCTGGTGCTGGCGTTGCTGATTTTCACGGCGATCGTCTGGACCCTGCGGCGGCTGTCGGATCG
GCCGCCGACGCTGGCGTCAATTCGATTGCGGGTAACGAGCGGCGTTCTGCTGGTGCTGGTGTTTGTGCAGCTTTATTTTG
GAGCGCTGGTCGCCGGGCTGCGGGCAGGGCGCGTCTTCAACACATGGCCGGACATCGACGGATCGTTCATTCCATCCGCG
GACAGGCTGTTCTTCGAGCAGCCATGGTGGCGCAATCTGTTCGACAACACGCTCACGGTTCAGTTCCAGCATCGCATGAT
GGCGTATGCGCTGTTTGCGGTTGCGGTTCTCCATCTGATCGATGCTCTCGTATCGCGCGCGAACCCCGCTATTGTTCGCG
GAGCTCTTTGGCTCGCCCTCGCGATGACGCTACAGGCGACGCTTGGCATCCTGACCCTCCTGTACGAGGTTCCCATCATG
CTCGCCCTGGTGCATCAAGGGGTCGCGATTGTGGTGCTGACGCTTGCGATCGTTCAGGCTGAGCGGATGACCGAGGGCCA
ATCCGCCCGGCAACGCCAGGAACTGGGCGTGGCGGCCGGATAG

Upstream 100 bases:

>100_bases
CATACCTTAAAATGAAACTCGCGACTGAGACGGAGGCTTGCGCCGGGGCTGCGGTGGACTATAAAGAGCACGAAAAATAC
CTTCAACCGCGGCTTTTTTG

Downstream 100 bases:

>100_bases
TTTTCTATCGGCGCGGGGGCCGAGCGGCTTTGCTTGGATTCGATACCGCAGTGTTGATACCGCGCAGGAGTGGCATCGGA
TCGGACCGGGCCTGAGGCTG

Product: cytochrome oxidase assembly

Products: NA

Alternate protein names: HAS; Cytochrome aa3-controlling protein

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MTRPIAQKESHLRAVRWWLVFMALLIAAMVLVGGATRLTESGLSIVEWKPVTGSLPPLSQAEWIQAFEGYKAIPQYREMN
AGMTLDQFKTIFWWEWSHRLLGRFIGIAFLLPFLWFMWRGALPSDLKRRLWIIFGLGGLQGAVGWWMVASGLTERTEVSQ
YRLATHLVLALLIFTAIVWTLRRLSDRPPTLASIRLRVTSGVLLVLVFVQLYFGALVAGLRAGRVFNTWPDIDGSFIPSA
DRLFFEQPWWRNLFDNTLTVQFQHRMMAYALFAVAVLHLIDALVSRANPAIVRGALWLALAMTLQATLGILTLLYEVPIM
LALVHQGVAIVVLTLAIVQAERMTEGQSARQRQELGVAAG

Sequences:

>Translated_360_residues
MTRPIAQKESHLRAVRWWLVFMALLIAAMVLVGGATRLTESGLSIVEWKPVTGSLPPLSQAEWIQAFEGYKAIPQYREMN
AGMTLDQFKTIFWWEWSHRLLGRFIGIAFLLPFLWFMWRGALPSDLKRRLWIIFGLGGLQGAVGWWMVASGLTERTEVSQ
YRLATHLVLALLIFTAIVWTLRRLSDRPPTLASIRLRVTSGVLLVLVFVQLYFGALVAGLRAGRVFNTWPDIDGSFIPSA
DRLFFEQPWWRNLFDNTLTVQFQHRMMAYALFAVAVLHLIDALVSRANPAIVRGALWLALAMTLQATLGILTLLYEVPIM
LALVHQGVAIVVLTLAIVQAERMTEGQSARQRQELGVAAG
>Mature_359_residues
TRPIAQKESHLRAVRWWLVFMALLIAAMVLVGGATRLTESGLSIVEWKPVTGSLPPLSQAEWIQAFEGYKAIPQYREMNA
GMTLDQFKTIFWWEWSHRLLGRFIGIAFLLPFLWFMWRGALPSDLKRRLWIIFGLGGLQGAVGWWMVASGLTERTEVSQY
RLATHLVLALLIFTAIVWTLRRLSDRPPTLASIRLRVTSGVLLVLVFVQLYFGALVAGLRAGRVFNTWPDIDGSFIPSAD
RLFFEQPWWRNLFDNTLTVQFQHRMMAYALFAVAVLHLIDALVSRANPAIVRGALWLALAMTLQATLGILTLLYEVPIML
ALVHQGVAIVVLTLAIVQAERMTEGQSARQRQELGVAAG

Specific function: Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group

COG id: COG1612

COG function: function code O; Uncharacterized protein required for cytochrome oxidase assembly

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX15/CtaA family. Type 2 subfamily

Homologues:

Organism=Homo sapiens, GI17921985, Length=336, Percent_Identity=39.5833333333333, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI17921987, Length=302, Percent_Identity=38.7417218543046, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17536069, Length=344, Percent_Identity=38.953488372093, Blast_Score=219, Evalue=2e-57,
Organism=Saccharomyces cerevisiae, GI6320989, Length=382, Percent_Identity=40.5759162303665, Blast_Score=235, Evalue=8e-63,
Organism=Drosophila melanogaster, GI19922860, Length=353, Percent_Identity=37.3937677053824, Blast_Score=190, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CTAA_NITWN (Q3SSR2)

Other databases:

- EMBL:   CP000115
- RefSeq:   YP_318031.1
- STRING:   Q3SSR2
- GeneID:   3675246
- GenomeReviews:   CP000115_GR
- KEGG:   nwi:Nwi_1418
- NMPDR:   fig|323098.3.peg.1459
- eggNOG:   COG1612
- HOGENOM:   HBG628966
- OMA:   GLSIVEW
- PhylomeDB:   Q3SSR2
- ProtClustDB:   CLSK2756834
- BioCyc:   NWIN323098:NWI_1418-MONOMER
- HAMAP:   MF_01665
- InterPro:   IPR003780

Pfam domain/function: PF02628 COX15-CtaA

EC number: NA

Molecular weight: Translated: 40582; Mature: 40450

Theoretical pI: Translated: 10.96; Mature: 10.96

Prosite motif: NA

Important sites: BINDING 325-325

Signals:

None

Transmembrane regions:

HASH(0xe4acd64)-; HASH(0xffbf9d4)-; HASH(0xf8a9c38)-; HASH(0x1013c9c4)-; HASH(0x100d64e4)-; HASH(0xdfa1ed8)-; HASH(0xe626504)-; HASH(0xe6106d0)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRPIAQKESHLRAVRWWLVFMALLIAAMVLVGGATRLTESGLSIVEWKPVTGSLPPLSQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEECCCCCCCCCCH
AEWIQAFEGYKAIPQYREMNAGMTLDQFKTIFWWEWSHRLLGRFIGIAFLLPFLWFMWRG
HHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ALPSDLKRRLWIIFGLGGLQGAVGWWMVASGLTERTEVSQYRLATHLVLALLIFTAIVWT
CCCHHHHHHEEHEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRRLSDRPPTLASIRLRVTSGVLLVLVFVQLYFGALVAGLRAGRVFNTWPDIDGSFIPSA
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCH
DRLFFEQPWWRNLFDNTLTVQFQHRMMAYALFAVAVLHLIDALVSRANPAIVRGALWLAL
HHHHHCCCHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AMTLQATLGILTLLYEVPIMLALVHQGVAIVVLTLAIVQAERMTEGQSARQRQELGVAAG
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCH
>Mature Secondary Structure 
TRPIAQKESHLRAVRWWLVFMALLIAAMVLVGGATRLTESGLSIVEWKPVTGSLPPLSQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEECCCCCCCCCCH
AEWIQAFEGYKAIPQYREMNAGMTLDQFKTIFWWEWSHRLLGRFIGIAFLLPFLWFMWRG
HHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ALPSDLKRRLWIIFGLGGLQGAVGWWMVASGLTERTEVSQYRLATHLVLALLIFTAIVWT
CCCHHHHHHEEHEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRRLSDRPPTLASIRLRVTSGVLLVLVFVQLYFGALVAGLRAGRVFNTWPDIDGSFIPSA
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCH
DRLFFEQPWWRNLFDNTLTVQFQHRMMAYALFAVAVLHLIDALVSRANPAIVRGALWLAL
HHHHHCCCHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AMTLQATLGILTLLYEVPIMLALVHQGVAIVVLTLAIVQAERMTEGQSARQRQELGVAAG
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA