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The map label for this gene is exbB [H]

Identifier: 75675459

GI number: 75675459

Start: 1399602

End: 1400558

Strand: Direct

Name: exbB [H]

Synonym: Nwi_1267

Alternate gene names: 75675459

Gene position: 1399602-1400558 (Clockwise)

Preceding gene: 75675448

Following gene: 75675460

Centisome position: 41.14

GC content: 68.34

Gene sequence:

>957_bases
ATGTTTAGAACGTCACTGAGGACGATTTCACTCGCCGCCGCGTTGATCATGGGGTCGCTTGTTTCATCCGCGATCGCGCA
ACAGAACGGCTCGCAACAAAGCGTTGCGCATCCGACCGCGCCATCCGCGCAGACGCCGGCCGTTTCCGCGCCGGCACCGC
CGGTTCAAGCGCCGCCGATCTCCAATGCGTCGGAACCTGCTACCGCCGCCACTCCGTCTCCAGCCGGCACCGCCGGCGTC
AACCTGCTGAATCCCGACACCGCTTCGCCTCACGAGTTATCTCCGTGGTCGATGTTCATGTCGGCGGATATTGTCGTTCA
GCTGGTGATGATCGGTCTTGCGTTTGCGTCGCTGGTGACGTGGACGATCTGCATCGCGAAGCTGGCGGAGCTGTCGCTGG
CGCGGCGCGCGCTGCGGGCGGCGCTGAACAAGATCGGCGACGCGCGCTCGCTGGCGGAAGCGCAGATGGCGCTCGGCGCG
CGGGAGGGCGTGCTGGCCTCGCTGCTGGCCTCGGCGATGCACGAGGCGCGGCTTTCGGCCGGCATTTCCAGCGACGCCGG
CATCAAGGAGCGCGCGGCGTCGAGCTTCGCCGAGATCGTCCGCGCGGAATCGCGCCGCATCCGGCTCGGCATGGGGCTGC
TCGCCACCATCGGCGCGACGTCGCCGTTCGTCGGCCTGTTCGGCACCGTGTGGGGCATCATGAACAGCTTCATCGGGATT
TCGAAGTCGCAGACCACCAACCTCGCGGTGGTGGCGCCCGGCATCGCCGAGGCGCTGCTCGCGACCGCGCTCGGCCTTGT
CGCCGCCATTCCGGCGGTCATCATCTACAACTACTTCGCGCGCGTGACGCGGGGCTACACCGAACTGGTCGGGCGCGCCT
CGGGAGCGGCCGGCCGGCTGCTGTCGCGCGATCTGGACCGCACCCACGGTTCCCTCACCTCGCGCGCGGCGGAGTAG

Upstream 100 bases:

>100_bases
CATCGGATGCTTCGGCTGACATCATGAGACCGGCTGATGATCCTGGAATGGTTAACCAGCATTACGATCTTGTTTTCATT
AGGCCGGGGTGAACGCGTTG

Downstream 100 bases:

>100_bases
GCCGATGGGCGCATCGATCGCGGAAGGCGGCTTCGACGACGACGAGGAGTACGGCGAAGCCCACGAGATCAACGTCACGC
CGTTCATCGACGTGATCCTG

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MFRTSLRTISLAAALIMGSLVSSAIAQQNGSQQSVAHPTAPSAQTPAVSAPAPPVQAPPISNASEPATAATPSPAGTAGV
NLLNPDTASPHELSPWSMFMSADIVVQLVMIGLAFASLVTWTICIAKLAELSLARRALRAALNKIGDARSLAEAQMALGA
REGVLASLLASAMHEARLSAGISSDAGIKERAASSFAEIVRAESRRIRLGMGLLATIGATSPFVGLFGTVWGIMNSFIGI
SKSQTTNLAVVAPGIAEALLATALGLVAAIPAVIIYNYFARVTRGYTELVGRASGAAGRLLSRDLDRTHGSLTSRAAE

Sequences:

>Translated_318_residues
MFRTSLRTISLAAALIMGSLVSSAIAQQNGSQQSVAHPTAPSAQTPAVSAPAPPVQAPPISNASEPATAATPSPAGTAGV
NLLNPDTASPHELSPWSMFMSADIVVQLVMIGLAFASLVTWTICIAKLAELSLARRALRAALNKIGDARSLAEAQMALGA
REGVLASLLASAMHEARLSAGISSDAGIKERAASSFAEIVRAESRRIRLGMGLLATIGATSPFVGLFGTVWGIMNSFIGI
SKSQTTNLAVVAPGIAEALLATALGLVAAIPAVIIYNYFARVTRGYTELVGRASGAAGRLLSRDLDRTHGSLTSRAAE
>Mature_318_residues
MFRTSLRTISLAAALIMGSLVSSAIAQQNGSQQSVAHPTAPSAQTPAVSAPAPPVQAPPISNASEPATAATPSPAGTAGV
NLLNPDTASPHELSPWSMFMSADIVVQLVMIGLAFASLVTWTICIAKLAELSLARRALRAALNKIGDARSLAEAQMALGA
REGVLASLLASAMHEARLSAGISSDAGIKERAASSFAEIVRAESRRIRLGMGLLATIGATSPFVGLFGTVWGIMNSFIGI
SKSQTTNLAVVAPGIAEALLATALGLVAAIPAVIIYNYFARVTRGYTELVGRASGAAGRLLSRDLDRTHGSLTSRAAE

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1789381, Length=231, Percent_Identity=52.3809523809524, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI1786958, Length=199, Percent_Identity=35.678391959799, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014164 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 32594; Mature: 32594

Theoretical pI: Translated: 10.59; Mature: 10.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRTSLRTISLAAALIMGSLVSSAIAQQNGSQQSVAHPTAPSAQTPAVSAPAPPVQAPPI
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SNASEPATAATPSPAGTAGVNLLNPDTASPHELSPWSMFMSADIVVQLVMIGLAFASLVT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
WTICIAKLAELSLARRALRAALNKIGDARSLAEAQMALGAREGVLASLLASAMHEARLSA
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GISSDAGIKERAASSFAEIVRAESRRIRLGMGLLATIGATSPFVGLFGTVWGIMNSFIGI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
SKSQTTNLAVVAPGIAEALLATALGLVAAIPAVIIYNYFARVTRGYTELVGRASGAAGRL
CCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LSRDLDRTHGSLTSRAAE
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFRTSLRTISLAAALIMGSLVSSAIAQQNGSQQSVAHPTAPSAQTPAVSAPAPPVQAPPI
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SNASEPATAATPSPAGTAGVNLLNPDTASPHELSPWSMFMSADIVVQLVMIGLAFASLVT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
WTICIAKLAELSLARRALRAALNKIGDARSLAEAQMALGAREGVLASLLASAMHEARLSA
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GISSDAGIKERAASSFAEIVRAESRRIRLGMGLLATIGATSPFVGLFGTVWGIMNSFIGI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
SKSQTTNLAVVAPGIAEALLATALGLVAAIPAVIIYNYFARVTRGYTELVGRASGAAGRL
CCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LSRDLDRTHGSLTSRAAE
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8437515 [H]