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The map label for this gene is prtE [H]

Identifier: 75675156

GI number: 75675156

Start: 1058387

End: 1059730

Strand: Direct

Name: prtE [H]

Synonym: Nwi_0963

Alternate gene names: 75675156

Gene position: 1058387-1059730 (Clockwise)

Preceding gene: 75675155

Following gene: 75675157

Centisome position: 31.11

GC content: 60.71

Gene sequence:

>1344_bases
ATGAGCATGACAGCGACCGGCGATCAGCCCTGGCACGTCGACCTTCCACGCTCGACACGAGGCCTCACCCTTGCAGGCGT
GGTGATCGTCGCTGTGACGGTGCTGGGATTCGGTGTCTGGGGCAACACAGCGCCGATTGCCGGCGCCGTCGTGGCGTCCG
GCGTGTTCGTGGCCACAGGCCAGAACAAGATCATTCAGCATCTTGAAGGCGGCATGATCGACGAGATCAAGGTTCGCGAA
GGTGACACCGTGGAACCCGGACAGATCCTCGTTGAACTGGACCGGACTTCGGCGAAAGCCGAAATGCAGCGGCTCTTCCT
TCGCAACGCGCGGCTCACGGCCCTCGATGCGCGCTTGCAGGCACAGGTTCGCGAGGAAACGGAAGTCCACTTTCCGCCGG
AACTGGCATCCGATTCAAAGGATCCGCAGATACGCAGCATCGTCAACGCTCAACTGCTTTCTTTTACGGCCCAACGCAAC
AATGCCAACAGCGATATTGCCGGGATTGAGGATAGCATCAAGGCCCTGAACGAGCGCATCGCGGGTTCCAAGGTTCAACT
CGACGGCGTGCGGCGACAGATCGCGCTGATCGAAGAAGATATCAAGACCAAGGAGCACCTTTTGGCGGCGGGGCTCGTGC
GCAAGCCCGAGGTTCTTCTTCTGCAACGCAATCAGGCCAATCTGGAAGGCGAGGTCGGCCGCATCATGGGCGACATCGGT
GACGCCAAGGAGCGGATATCCCGCGCGGTCGAGCAGATCAACGGCGTGCGGAAGGTCGCCATCAAGACCGCCGTCGAACA
GATGCACGAAGTGCGTGGTGAACTGGCCGATGTCCGCGAGCGGATGCAGAGCGCAAAGGGCGTCCTTGACCGGACCACGA
TCCGCGCGCCGGTCAAGGGCGTCGTCGTCAAGCTGCGATTTCATACGCGCGGCGGCGTGGTGGAGCCGGGAAAGCCCATC
ATGGAGTTGCTGCCGCTTGATGAGCCGTTGATCATCGAAGCCAGGGTGAGGCCCCAGGATATCGACTCGGTCAAGCACGG
CCAGGAAGCGATGGTTCGGCTGACGGCGCTCAGCCAGCGGATTACGCCGATGGTTTCCGGAGACGTTATCTATCTCTCGG
CCGATACGGTCGCCGACGAAAAGAAGTCGCAACAGACCGGACCGAGCGACATCTATGTCATTCGCGTGCGGCTGAACAAC
GCCGAAGTTGTCGCGATCCACGGCTTCCATCCGACGCCGGGCATGCCGGCTGAAGTCTTCATCAAGACCAGCGAACGAAC
CTTCTTCCAGTACATCATGAAGCCGATCGATGACAGCATGTCACGGGCGTTTCGCGAGCGATAG

Upstream 100 bases:

>100_bases
ATTCCGCTGATGTCAGGCCGCAAACGACCCAGCCCTTCCGCCGCGCCAATGCTCGACGCATGATCAGGGGCCAGACAGAC
GCGAGCCTGGAGAGACGAGC

Downstream 100 bases:

>100_bases
GAGCACGGCGGGGGGACGCAAAAGAGCAGACAACATGAGCGCGCAAAGAGGGCTCCAATGCACATCGACCTCATAGAGGA
TATGGATACTTTCAGCCGGT

Product: type I secretion membrane fusion protein, HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MSMTATGDQPWHVDLPRSTRGLTLAGVVIVAVTVLGFGVWGNTAPIAGAVVASGVFVATGQNKIIQHLEGGMIDEIKVRE
GDTVEPGQILVELDRTSAKAEMQRLFLRNARLTALDARLQAQVREETEVHFPPELASDSKDPQIRSIVNAQLLSFTAQRN
NANSDIAGIEDSIKALNERIAGSKVQLDGVRRQIALIEEDIKTKEHLLAAGLVRKPEVLLLQRNQANLEGEVGRIMGDIG
DAKERISRAVEQINGVRKVAIKTAVEQMHEVRGELADVRERMQSAKGVLDRTTIRAPVKGVVVKLRFHTRGGVVEPGKPI
MELLPLDEPLIIEARVRPQDIDSVKHGQEAMVRLTALSQRITPMVSGDVIYLSADTVADEKKSQQTGPSDIYVIRVRLNN
AEVVAIHGFHPTPGMPAEVFIKTSERTFFQYIMKPIDDSMSRAFRER

Sequences:

>Translated_447_residues
MSMTATGDQPWHVDLPRSTRGLTLAGVVIVAVTVLGFGVWGNTAPIAGAVVASGVFVATGQNKIIQHLEGGMIDEIKVRE
GDTVEPGQILVELDRTSAKAEMQRLFLRNARLTALDARLQAQVREETEVHFPPELASDSKDPQIRSIVNAQLLSFTAQRN
NANSDIAGIEDSIKALNERIAGSKVQLDGVRRQIALIEEDIKTKEHLLAAGLVRKPEVLLLQRNQANLEGEVGRIMGDIG
DAKERISRAVEQINGVRKVAIKTAVEQMHEVRGELADVRERMQSAKGVLDRTTIRAPVKGVVVKLRFHTRGGVVEPGKPI
MELLPLDEPLIIEARVRPQDIDSVKHGQEAMVRLTALSQRITPMVSGDVIYLSADTVADEKKSQQTGPSDIYVIRVRLNN
AEVVAIHGFHPTPGMPAEVFIKTSERTFFQYIMKPIDDSMSRAFRER
>Mature_446_residues
SMTATGDQPWHVDLPRSTRGLTLAGVVIVAVTVLGFGVWGNTAPIAGAVVASGVFVATGQNKIIQHLEGGMIDEIKVREG
DTVEPGQILVELDRTSAKAEMQRLFLRNARLTALDARLQAQVREETEVHFPPELASDSKDPQIRSIVNAQLLSFTAQRNN
ANSDIAGIEDSIKALNERIAGSKVQLDGVRRQIALIEEDIKTKEHLLAAGLVRKPEVLLLQRNQANLEGEVGRIMGDIGD
AKERISRAVEQINGVRKVAIKTAVEQMHEVRGELADVRERMQSAKGVLDRTTIRAPVKGVVVKLRFHTRGGVVEPGKPIM
ELLPLDEPLIIEARVRPQDIDSVKHGQEAMVRLTALSQRITPMVSGDVIYLSADTVADEKKSQQTGPSDIYVIRVRLNNA
EVVAIHGFHPTPGMPAEVFIKTSERTFFQYIMKPIDDSMSRAFRER

Specific function: Involved in the secretion of proteases A, B, C and G [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 49170; Mature: 49039

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMTATGDQPWHVDLPRSTRGLTLAGVVIVAVTVLGFGVWGNTAPIAGAVVASGVFVATG
CCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCEEEECC
QNKIIQHLEGGMIDEIKVREGDTVEPGQILVELDRTSAKAEMQRLFLRNARLTALDARLQ
CHHHHHHHCCCCEEEEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHH
AQVREETEVHFPPELASDSKDPQIRSIVNAQLLSFTAQRNNANSDIAGIEDSIKALNERI
HHHHHCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
AGSKVQLDGVRRQIALIEEDIKTKEHLLAAGLVRKPEVLLLQRNQANLEGEVGRIMGDIG
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHCCC
DAKERISRAVEQINGVRKVAIKTAVEQMHEVRGELADVRERMQSAKGVLDRTTIRAPVKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCE
VVVKLRFHTRGGVVEPGKPIMELLPLDEPLIIEARVRPQDIDSVKHGQEAMVRLTALSQR
EEEEEEEECCCCCCCCCCHHHHHCCCCCCEEEEEECCCCHHHHHHCCHHHHHHHHHHHHH
ITPMVSGDVIYLSADTVADEKKSQQTGPSDIYVIRVRLNNAEVVAIHGFHPTPGMPAEVF
CCCEECCCEEEEECCCHHHHHHHCCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCEEE
IKTSERTFFQYIMKPIDDSMSRAFRER
EECCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SMTATGDQPWHVDLPRSTRGLTLAGVVIVAVTVLGFGVWGNTAPIAGAVVASGVFVATG
CCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCEEEECC
QNKIIQHLEGGMIDEIKVREGDTVEPGQILVELDRTSAKAEMQRLFLRNARLTALDARLQ
CHHHHHHHCCCCEEEEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHH
AQVREETEVHFPPELASDSKDPQIRSIVNAQLLSFTAQRNNANSDIAGIEDSIKALNERI
HHHHHCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
AGSKVQLDGVRRQIALIEEDIKTKEHLLAAGLVRKPEVLLLQRNQANLEGEVGRIMGDIG
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHCCC
DAKERISRAVEQINGVRKVAIKTAVEQMHEVRGELADVRERMQSAKGVLDRTTIRAPVKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCE
VVVKLRFHTRGGVVEPGKPIMELLPLDEPLIIEARVRPQDIDSVKHGQEAMVRLTALSQR
EEEEEEEECCCCCCCCCCHHHHHCCCCCCEEEEEECCCCHHHHHHCCHHHHHHHHHHHHH
ITPMVSGDVIYLSADTVADEKKSQQTGPSDIYVIRVRLNNAEVVAIHGFHPTPGMPAEVF
CCCEECCCEEEEECCCHHHHHHHCCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCEEE
IKTSERTFFQYIMKPIDDSMSRAFRER
EECCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2184029 [H]