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The map label for this gene is hsaA [H]

Identifier: 75675130

GI number: 75675130

Start: 1026845

End: 1028074

Strand: Direct

Name: hsaA [H]

Synonym: Nwi_0937

Alternate gene names: 75675130

Gene position: 1026845-1028074 (Clockwise)

Preceding gene: 75675129

Following gene: 75675131

Centisome position: 30.18

GC content: 63.82

Gene sequence:

>1230_bases
ATGGCAGGTAACGATCCTGGCGCGCCTGCAAATCCGGCAGAGTCCGACGCAGGCGATCATGCCTACGCAGCCGTGATGGC
GCGGGCGAGGGCGCTGGTGCCGGAGCTACGTGATCGGGCTGCCAGAAGCGAGGAGTTGCGGCGTCTGCCGCCGGAGACCG
AGAAGGAATTTCATGACGCCGGATTATTCAAGATCCTGCAGCCGAGGCGGGTCGGCGGCCTTGAACTCGACTACGTTGCT
CTGGTTGACCTTGCCGAGGCGATTGCCGTCGCCGACGCATCCGCGGCCTGGACGCTGGCCAACCTTGCGAGTCATCACTG
GATGCTCGGCATGTTCGACCGTCGGGCCCAGGACGCCGTCTGGGCGAAAGATCCAAATGCTTTGATCGCGTCGTCCTTCG
TGTTTCCTTCCGGTCGCGCCACCAAGGTCGAGGGTGGGTATCGCTTGCAGGGGCGCTGGCCGTTCTCCTCGGGAGTGGAC
TGCTGCACGTGGAACATGCTCGCCGGGCACGTTTCATCCGATGATGAAGCAGATGGCATCGAGTACAGGATTTTCCTGGT
CCCTCGCGAGCGCTATCGGATCATCGATATGTGGAACGCCGCGGGCCTGAAAGGAACGGGCTCGAACGACGTTGCAGCCG
ACGACCTCTTCGTCGAGGAGGCGATGACCCTGTCGGTCGCGGATATCGCCGGAGGTCCGTCACCCGGCAGCGCCGTCAAT
CCGAATCCGCTTTATGCGCTGCCGGTCTTCGCGCTGTTTCCGTTCGTGCTGTCCGGGGTGGCGCTCGGCAACGCCCAGGG
GTGTCTCAATGACTACATCGAGATCGCGCGGCACCGCGCAACCACTTTCAACCGCGCCAGGCTCGGCGATCTCCAGTCCA
CGCAGATCAAGATCGCCGAAGCGTCCGCGAAGATCGACGCCGCTCGCCTGGTCATGCGCTCGATCTGCATCAGGGCGATT
TCCGATGCGAAACGCGGGCTTGTCCCCGACATGGCGGTGAAAACCGGGTGGCGGCGCGATGGCGCTTATGCCGTGACCTT
GTGCACGGAAGCGGTGTCGTTGCTGTTTGCGTCAAGCGGCGCGCGCGGATTGTTCGCCGCCGCTCCGCTGCAGCGCCAGT
TCCGCGATGCGGTCGCGATCAACTCCCATATCGCATTCAGCTTCGATGCTGCGGGCACGGATTACGGCCGGGTCGCCCTC
GGGCTGCCGTCGCAGAATCTGACGTTGTGA

Upstream 100 bases:

>100_bases
TTGTTGCTCCCCCTTTTGCTCCCTTGTAGTTAGGGAGGTGCGCCTCACAACGTCCGCTGTATGGGCGAAGTCGGCCAGCC
TAATTTCAGGGGATTGTCGA

Downstream 100 bases:

>100_bases
GGCGTCTGATGACTGACGGTTCTGAACTTCCCGACACGCCGGATCCGGCTCGTGAACTGGCGAGCGGGGAGTCGACTCTC
GATCCGCGCGACTTCCGCAA

Product: putative pigment protein

Products: NA

Alternate protein names: 3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione 4-hydroxylase [H]

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MAGNDPGAPANPAESDAGDHAYAAVMARARALVPELRDRAARSEELRRLPPETEKEFHDAGLFKILQPRRVGGLELDYVA
LVDLAEAIAVADASAAWTLANLASHHWMLGMFDRRAQDAVWAKDPNALIASSFVFPSGRATKVEGGYRLQGRWPFSSGVD
CCTWNMLAGHVSSDDEADGIEYRIFLVPRERYRIIDMWNAAGLKGTGSNDVAADDLFVEEAMTLSVADIAGGPSPGSAVN
PNPLYALPVFALFPFVLSGVALGNAQGCLNDYIEIARHRATTFNRARLGDLQSTQIKIAEASAKIDAARLVMRSICIRAI
SDAKRGLVPDMAVKTGWRRDGAYAVTLCTEAVSLLFASSGARGLFAAAPLQRQFRDAVAINSHIAFSFDAAGTDYGRVAL
GLPSQNLTL

Sequences:

>Translated_409_residues
MAGNDPGAPANPAESDAGDHAYAAVMARARALVPELRDRAARSEELRRLPPETEKEFHDAGLFKILQPRRVGGLELDYVA
LVDLAEAIAVADASAAWTLANLASHHWMLGMFDRRAQDAVWAKDPNALIASSFVFPSGRATKVEGGYRLQGRWPFSSGVD
CCTWNMLAGHVSSDDEADGIEYRIFLVPRERYRIIDMWNAAGLKGTGSNDVAADDLFVEEAMTLSVADIAGGPSPGSAVN
PNPLYALPVFALFPFVLSGVALGNAQGCLNDYIEIARHRATTFNRARLGDLQSTQIKIAEASAKIDAARLVMRSICIRAI
SDAKRGLVPDMAVKTGWRRDGAYAVTLCTEAVSLLFASSGARGLFAAAPLQRQFRDAVAINSHIAFSFDAAGTDYGRVAL
GLPSQNLTL
>Mature_408_residues
AGNDPGAPANPAESDAGDHAYAAVMARARALVPELRDRAARSEELRRLPPETEKEFHDAGLFKILQPRRVGGLELDYVAL
VDLAEAIAVADASAAWTLANLASHHWMLGMFDRRAQDAVWAKDPNALIASSFVFPSGRATKVEGGYRLQGRWPFSSGVDC
CTWNMLAGHVSSDDEADGIEYRIFLVPRERYRIIDMWNAAGLKGTGSNDVAADDLFVEEAMTLSVADIAGGPSPGSAVNP
NPLYALPVFALFPFVLSGVALGNAQGCLNDYIEIARHRATTFNRARLGDLQSTQIKIAEASAKIDAARLVMRSICIRAIS
DAKRGLVPDMAVKTGWRRDGAYAVTLCTEAVSLLFASSGARGLFAAAPLQRQFRDAVAINSHIAFSFDAAGTDYGRVALG
LPSQNLTL

Specific function: Catalyzes the o-hydroxylation of 3-hydroxy-9,10- seconandrost-1,3,5(10)-triene-9,17-dione (3-HSA) to 3,4-dihydroxy- 9,10-seconandrost-1,3,5(10)-triene-9,17-dione (3,4-DHSA) in the catabolism of cholesterol [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FADH(2)-utilizing monooxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013107
- InterPro:   IPR006092
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF08028 Acyl-CoA_dh_2; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 43892; Mature: 43761

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGNDPGAPANPAESDAGDHAYAAVMARARALVPELRDRAARSEELRRLPPETEKEFHDA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHC
GLFKILQPRRVGGLELDYVALVDLAEAIAVADASAAWTLANLASHHWMLGMFDRRAQDAV
CHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHCCCC
WAKDPNALIASSFVFPSGRATKVEGGYRLQGRWPFSSGVDCCTWNMLAGHVSSDDEADGI
CCCCCCCCEEEEEECCCCCCEEECCCEEEEEECCCCCCCCEEEHHHHHCCCCCCCCCCCE
EYRIFLVPRERYRIIDMWNAAGLKGTGSNDVAADDLFVEEAMTLSVADIAGGPSPGSAVN
EEEEEEEECCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHEEEEHHHCCCCCCCCCCC
PNPLYALPVFALFPFVLSGVALGNAQGCLNDYIEIARHRATTFNRARLGDLQSTQIKIAE
CCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCCCCCEEEEEH
ASAKIDAARLVMRSICIRAISDAKRGLVPDMAVKTGWRRDGAYAVTLCTEAVSLLFASSG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCEEEHHHHHHHHHHHHCCC
ARGLFAAAPLQRQFRDAVAINSHIAFSFDAAGTDYGRVALGLPSQNLTL
CCCEEECCHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEECCCCCCCC
>Mature Secondary Structure 
AGNDPGAPANPAESDAGDHAYAAVMARARALVPELRDRAARSEELRRLPPETEKEFHDA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHC
GLFKILQPRRVGGLELDYVALVDLAEAIAVADASAAWTLANLASHHWMLGMFDRRAQDAV
CHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHCCCC
WAKDPNALIASSFVFPSGRATKVEGGYRLQGRWPFSSGVDCCTWNMLAGHVSSDDEADGI
CCCCCCCCEEEEEECCCCCCEEECCCEEEEEECCCCCCCCEEEHHHHHCCCCCCCCCCCE
EYRIFLVPRERYRIIDMWNAAGLKGTGSNDVAADDLFVEEAMTLSVADIAGGPSPGSAVN
EEEEEEEECCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHEEEEHHHCCCCCCCCCCC
PNPLYALPVFALFPFVLSGVALGNAQGCLNDYIEIARHRATTFNRARLGDLQSTQIKIAE
CCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCCCCCEEEEEH
ASAKIDAARLVMRSICIRAISDAKRGLVPDMAVKTGWRRDGAYAVTLCTEAVSLLFASSG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCEEEHHHHHHHHHHHHCCC
ARGLFAAAPLQRQFRDAVAINSHIAFSFDAAGTDYGRVALGLPSQNLTL
CCCEEECCHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA