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The map label for this gene is ahpC [C]

Identifier: 75675086

GI number: 75675086

Start: 970777

End: 971415

Strand: Direct

Name: ahpC [C]

Synonym: Nwi_0891

Alternate gene names: 75675086

Gene position: 970777-971415 (Clockwise)

Preceding gene: 75675083

Following gene: 75675087

Centisome position: 28.53

GC content: 61.97

Gene sequence:

>639_bases
ATGTCCCTTTTGATGAACGATGAGAGGCCTCGTCTCACTCCTTCTCCATTCCCGTTGCGGATGGGAGATGCCGCCCCCGA
CTTCGAAGCCCGATCCACGAAGGGGCCGATCCGGCTTTCCGACTACAGAGGCCGGTGGCTCGTGTTCTTCTCGCACCCGG
CGGACTTTACGCCCGTATGCACCACGGAATTCGTCGCGCTGGCCAAAGCGCAAGACCGCTTCGCCGCGCTGGACTGTGCC
CTTCTGGGTCTTTCGGTCGACAGTCTTTATTCGCACCTCGCCTGGACCCGGACCATCACGGAACTGTTCGCGGTGGAGAT
TCCATTTCCGGTGATCGAGGACCCATCGATGATGGTAGGCCGCGCCTACGGCATGATCGACGAGGCCGCCGAGAGCAGCG
CGAGCGTGCGGGCAACCTATTTCATAGATCCCGAAGGCGTCATTCGCGCGATTACCCACTATCCGCTGACGATCGGCCGT
TCGATTGACGAGATGGTGCGGATGGTGGCGGCGCTGCAGGCGACCGCGTCGAGCCAGAAGTTGGCGCCGGCCAACTGGCG
GCCCGGAGAACCGCTGCTCCTGCCCGCCGATGAAAAAACGCAAAAGGATGTCAACTGGTTCTGCCGGAGCGTCGCATGA

Upstream 100 bases:

>100_bases
ACGTGATATTACGATTCCCATAATTATATAGTTATGTAAGTGTTTTGGGATGAATCGTCATTAGACAGGAACCTCCAGAC
AGGAACCTCCAGGTAGCCCT

Downstream 100 bases:

>100_bases
GAGCTTTATGGCAGTCGCGCGAGCAAGCAGATTTTGCAGCTGACAGATTGCGCAAGTTCGCTCAGCCTCAACGCCTGATG
ATCCTGTCGCTGCTGCGGGA

Product: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MSLLMNDERPRLTPSPFPLRMGDAAPDFEARSTKGPIRLSDYRGRWLVFFSHPADFTPVCTTEFVALAKAQDRFAALDCA
LLGLSVDSLYSHLAWTRTITELFAVEIPFPVIEDPSMMVGRAYGMIDEAAESSASVRATYFIDPEGVIRAITHYPLTIGR
SIDEMVRMVAALQATASSQKLAPANWRPGEPLLLPADEKTQKDVNWFCRSVA

Sequences:

>Translated_212_residues
MSLLMNDERPRLTPSPFPLRMGDAAPDFEARSTKGPIRLSDYRGRWLVFFSHPADFTPVCTTEFVALAKAQDRFAALDCA
LLGLSVDSLYSHLAWTRTITELFAVEIPFPVIEDPSMMVGRAYGMIDEAAESSASVRATYFIDPEGVIRAITHYPLTIGR
SIDEMVRMVAALQATASSQKLAPANWRPGEPLLLPADEKTQKDVNWFCRSVA
>Mature_211_residues
SLLMNDERPRLTPSPFPLRMGDAAPDFEARSTKGPIRLSDYRGRWLVFFSHPADFTPVCTTEFVALAKAQDRFAALDCAL
LGLSVDSLYSHLAWTRTITELFAVEIPFPVIEDPSMMVGRAYGMIDEAAESSASVRATYFIDPEGVIRAITHYPLTIGRS
IDEMVRMVAALQATASSQKLAPANWRPGEPLLLPADEKTQKDVNWFCRSVA

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4505591, Length=189, Percent_Identity=35.978835978836, Blast_Score=138, Evalue=3e-33,
Organism=Homo sapiens, GI32455266, Length=189, Percent_Identity=35.978835978836, Blast_Score=138, Evalue=3e-33,
Organism=Homo sapiens, GI32455264, Length=189, Percent_Identity=35.978835978836, Blast_Score=138, Evalue=3e-33,
Organism=Homo sapiens, GI4758638, Length=188, Percent_Identity=37.7659574468085, Blast_Score=135, Evalue=3e-32,
Organism=Homo sapiens, GI32189392, Length=181, Percent_Identity=36.4640883977901, Blast_Score=129, Evalue=1e-30,
Organism=Homo sapiens, GI5453549, Length=182, Percent_Identity=35.7142857142857, Blast_Score=125, Evalue=3e-29,
Organism=Homo sapiens, GI32483377, Length=161, Percent_Identity=35.4037267080745, Blast_Score=119, Evalue=2e-27,
Organism=Homo sapiens, GI5802974, Length=161, Percent_Identity=35.4037267080745, Blast_Score=119, Evalue=2e-27,
Organism=Homo sapiens, GI33188454, Length=80, Percent_Identity=45, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1786822, Length=161, Percent_Identity=34.7826086956522, Blast_Score=97, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI32565831, Length=187, Percent_Identity=33.6898395721925, Blast_Score=123, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI193204376, Length=187, Percent_Identity=33.6898395721925, Blast_Score=123, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI17554494, Length=170, Percent_Identity=33.5294117647059, Blast_Score=114, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI25153706, Length=201, Percent_Identity=30.8457711442786, Blast_Score=107, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6319407, Length=185, Percent_Identity=41.0810810810811, Blast_Score=144, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6323613, Length=167, Percent_Identity=35.3293413173653, Blast_Score=106, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6320661, Length=170, Percent_Identity=35.2941176470588, Blast_Score=100, Evalue=1e-22,
Organism=Drosophila melanogaster, GI17975518, Length=197, Percent_Identity=40.1015228426396, Blast_Score=147, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24652434, Length=197, Percent_Identity=40.1015228426396, Blast_Score=147, Evalue=5e-36,
Organism=Drosophila melanogaster, GI24652436, Length=186, Percent_Identity=39.7849462365591, Blast_Score=146, Evalue=9e-36,
Organism=Drosophila melanogaster, GI17157991, Length=167, Percent_Identity=37.7245508982036, Blast_Score=131, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24641739, Length=167, Percent_Identity=37.7245508982036, Blast_Score=131, Evalue=2e-31,
Organism=Drosophila melanogaster, GI17738015, Length=176, Percent_Identity=34.0909090909091, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24656348, Length=183, Percent_Identity=34.4262295081967, Blast_Score=120, Evalue=9e-28,
Organism=Drosophila melanogaster, GI17864676, Length=183, Percent_Identity=34.4262295081967, Blast_Score=120, Evalue=9e-28,
Organism=Drosophila melanogaster, GI21357347, Length=176, Percent_Identity=36.3636363636364, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24581278, Length=184, Percent_Identity=32.0652173913043, Blast_Score=109, Evalue=2e-24,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 23527; Mature: 23396

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLMNDERPRLTPSPFPLRMGDAAPDFEARSTKGPIRLSDYRGRWLVFFSHPADFTPVC
CCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCEEEECCCCCEEEEECCCCCCCCCH
TTEFVALAKAQDRFAALDCALLGLSVDSLYSHLAWTRTITELFAVEIPFPVIEDPSMMVG
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHH
RAYGMIDEAAESSASVRATYFIDPEGVIRAITHYPLTIGRSIDEMVRMVAALQATASSQK
HHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCC
LAPANWRPGEPLLLPADEKTQKDVNWFCRSVA
CCCCCCCCCCCEEECCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SLLMNDERPRLTPSPFPLRMGDAAPDFEARSTKGPIRLSDYRGRWLVFFSHPADFTPVC
CCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCEEEECCCCCEEEEECCCCCCCCCH
TTEFVALAKAQDRFAALDCALLGLSVDSLYSHLAWTRTITELFAVEIPFPVIEDPSMMVG
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHH
RAYGMIDEAAESSASVRATYFIDPEGVIRAITHYPLTIGRSIDEMVRMVAALQATASSQK
HHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCC
LAPANWRPGEPLLLPADEKTQKDVNWFCRSVA
CCCCCCCCCCCEEECCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]