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The map label for this gene is bigR [H]

Identifier: 75675087

GI number: 75675087

Start: 971412

End: 971807

Strand: Direct

Name: bigR [H]

Synonym: Nwi_0892

Alternate gene names: 75675087

Gene position: 971412-971807 (Clockwise)

Preceding gene: 75675086

Following gene: 75675089

Centisome position: 28.55

GC content: 57.32

Gene sequence:

>396_bases
ATGAGAGCTTTATGGCAGTCGCGCGAGCAAGCAGATTTTGCAGCTGACAGATTGCGCAAGTTCGCTCAGCCTCAACGCCT
GATGATCCTGTCGCTGCTGCGGGAAGGCGAGAAGTCGGTGACGGAAATCGATGCGGCGACCGGGATCGGACAGCCTGCGC
TCAGCCAGCAACTCGCGGAACTCCGTAAGGCCGAACTCGTCACCACACGGCGACAGGCAAAGCAGATCTATTACAGTCTG
GCTCATGAGTCAGTGGCGCTTTGCGTTCGCAGCATCGAGGCTGTCTTCAATGCCGATAATCCGGAACAGGCATTGTTAAA
CGCCGTAAGGCACGACCTCCGTCCGGAAAGTGAAGACGTCGTTCATGGAGCGGCGAATTTCGCGCGGCTCCGTTAA

Upstream 100 bases:

>100_bases
AGAAGTTGGCGCCGGCCAACTGGCGGCCCGGAGAACCGCTGCTCCTGCCCGCCGATGAAAAAACGCAAAAGGATGTCAAC
TGGTTCTGCCGGAGCGTCGC

Downstream 100 bases:

>100_bases
CTCTCCCGCTTCTTGACAGCCTGGAAAATGATCCGATCCAGCCCGTTATCGCGATCGGGCGATCATTCGAAGGTGCTTGT
GAGGCGTCACAGCGATCCCG

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MRALWQSREQADFAADRLRKFAQPQRLMILSLLREGEKSVTEIDAATGIGQPALSQQLAELRKAELVTTRRQAKQIYYSL
AHESVALCVRSIEAVFNADNPEQALLNAVRHDLRPESEDVVHGAANFARLR

Sequences:

>Translated_131_residues
MRALWQSREQADFAADRLRKFAQPQRLMILSLLREGEKSVTEIDAATGIGQPALSQQLAELRKAELVTTRRQAKQIYYSL
AHESVALCVRSIEAVFNADNPEQALLNAVRHDLRPESEDVVHGAANFARLR
>Mature_131_residues
MRALWQSREQADFAADRLRKFAQPQRLMILSLLREGEKSVTEIDAATGIGQPALSQQLAELRKAELVTTRRQAKQIYYSL
AHESVALCVRSIEAVFNADNPEQALLNAVRHDLRPESEDVVHGAANFARLR

Specific function: Represses an operon that comprises itself, XF_0764, XF_0765, XF_0766 and blh. Binds to a palindromic AT-rich sequence spanning the -10 region of the blh promoter and blocks transcription of the operon [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 14753; Mature: 14753

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRALWQSREQADFAADRLRKFAQPQRLMILSLLREGEKSVTEIDAATGIGQPALSQQLAE
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LRKAELVTTRRQAKQIYYSLAHESVALCVRSIEAVFNADNPEQALLNAVRHDLRPESEDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHH
VHGAANFARLR
HHHHHHHHHCC
>Mature Secondary Structure
MRALWQSREQADFAADRLRKFAQPQRLMILSLLREGEKSVTEIDAATGIGQPALSQQLAE
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LRKAELVTTRRQAKQIYYSLAHESVALCVRSIEAVFNADNPEQALLNAVRHDLRPESEDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHH
VHGAANFARLR
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]