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The map label for this gene is dapA [H]

Identifier: 75675078

GI number: 75675078

Start: 959684

End: 960568

Strand: Direct

Name: dapA [H]

Synonym: Nwi_0883

Alternate gene names: 75675078

Gene position: 959684-960568 (Clockwise)

Preceding gene: 75675077

Following gene: 75675083

Centisome position: 28.21

GC content: 62.6

Gene sequence:

>885_bases
ATGCCCGATCTCGCTATTCAAGGCATCATTGGTTACACGATCACGCCCTTCGACAACCAAGGCCGCCTTGACTTGAACGC
GCTGGATCTGACTATCAACCGCATGATCGAGGCTGGCGTTCACGCCATCGCGCCCCTCGGCAGCACAGGCGAAGGCGCCT
ATTTGAGTGAGGAAGAGTGGACCGCCGTCGCCGAACGCAGCGTGAAGACCATCGCCGGCCGCGTCCCGGTGATCGTCAGC
GTCTCCGATCTAACGACGGCTGGCGCGGTGAGGCGCGCGCGAGCGGCGGAGTCGTTCGGCGCCACTGCGGTCATGGTCCT
GCCGACATCGTACTGGAAGCTGCAGGAAGACGAGATCGTCGCGCATTATCAGGCGGTAGGAACGGCCATTGGCGTGCCGG
TGATGCTCTACAACAACCATGCGGTCAGCGGGATCGACATGTCGGTTGATCTGATCCTGCGCATCGTGGACGCCGTCGAC
AATGTCACGATGGTCAAGGAAAGCACCGGCGACATCCAGCGGATGCATCAACTCTATCTGCGGACCGAAGGACAGCTTCC
GTTCTACAACGGCTCCAATCCCTTGGCTCTCGAAGCCTTCGCCGCTGGTGCGACCGGCTGGTGCACGGCCGCCGCCAATC
TGATCGCCGCCGACAACATAGCGCTCTACGAAGCAGCTCGGCAGGGTCGCCTCGTCGAGGCCCGAGCGTCCTTCTACCGG
CAGTTGCCGTTGCTCGACTTCATTCTCAAGGGCGGTTTGCCCAAGACGATCAAGGCCGGGCTCGAAATAGCCGGGGTGCC
GGTCGGAGCACCGCGGTTGCCGGTGAAGCCTCTGGACGAGGCGGGCAGAGCGAGGCTCTCGGCCATTCTCGAGACGCTGA
ACTGA

Upstream 100 bases:

>100_bases
GGCATTCGACTATTACTCCCGCAGAGTTCTGGGTCGCCACAACGACTGCCTGCTCTGAACTCCTGCGCTCGACTCCTCCT
ACTATTTTAAAGGACAGCAA

Downstream 100 bases:

>100_bases
ATAGCGAAGGGTGGCCAGCGTTCCAGTGGCCACCCTCATCGGAAGATTAGGTCGTGTTGACAAAGTGTCTGATCCAAAAG
GGATGACGCTGTCGCTCGCA

Product: dihydrodipicolinate synthetase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MPDLAIQGIIGYTITPFDNQGRLDLNALDLTINRMIEAGVHAIAPLGSTGEGAYLSEEEWTAVAERSVKTIAGRVPVIVS
VSDLTTAGAVRRARAAESFGATAVMVLPTSYWKLQEDEIVAHYQAVGTAIGVPVMLYNNHAVSGIDMSVDLILRIVDAVD
NVTMVKESTGDIQRMHQLYLRTEGQLPFYNGSNPLALEAFAAGATGWCTAAANLIAADNIALYEAARQGRLVEARASFYR
QLPLLDFILKGGLPKTIKAGLEIAGVPVGAPRLPVKPLDEAGRARLSAILETLN

Sequences:

>Translated_294_residues
MPDLAIQGIIGYTITPFDNQGRLDLNALDLTINRMIEAGVHAIAPLGSTGEGAYLSEEEWTAVAERSVKTIAGRVPVIVS
VSDLTTAGAVRRARAAESFGATAVMVLPTSYWKLQEDEIVAHYQAVGTAIGVPVMLYNNHAVSGIDMSVDLILRIVDAVD
NVTMVKESTGDIQRMHQLYLRTEGQLPFYNGSNPLALEAFAAGATGWCTAAANLIAADNIALYEAARQGRLVEARASFYR
QLPLLDFILKGGLPKTIKAGLEIAGVPVGAPRLPVKPLDEAGRARLSAILETLN
>Mature_293_residues
PDLAIQGIIGYTITPFDNQGRLDLNALDLTINRMIEAGVHAIAPLGSTGEGAYLSEEEWTAVAERSVKTIAGRVPVIVSV
SDLTTAGAVRRARAAESFGATAVMVLPTSYWKLQEDEIVAHYQAVGTAIGVPVMLYNNHAVSGIDMSVDLILRIVDAVDN
VTMVKESTGDIQRMHQLYLRTEGQLPFYNGSNPLALEAFAAGATGWCTAAANLIAADNIALYEAARQGRLVEARASFYRQ
LPLLDFILKGGLPKTIKAGLEIAGVPVGAPRLPVKPLDEAGRARLSAILETLN

Specific function: Unknown

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI13540533, Length=301, Percent_Identity=24.5847176079734, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI31543060, Length=290, Percent_Identity=25.1724137931034, Blast_Score=75, Evalue=5e-14,
Organism=Escherichia coli, GI1786463, Length=292, Percent_Identity=27.3972602739726, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI87082415, Length=281, Percent_Identity=27.7580071174377, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1788823, Length=285, Percent_Identity=26.6666666666667, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1789620, Length=292, Percent_Identity=27.3972602739726, Blast_Score=108, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 31365; Mature: 31234

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDLAIQGIIGYTITPFDNQGRLDLNALDLTINRMIEAGVHAIAPLGSTGEGAYLSEEEW
CCCCEEEEEECEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCHHH
TAVAERSVKTIAGRVPVIVSVSDLTTAGAVRRARAAESFGATAVMVLPTSYWKLQEDEIV
HHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHCCCEEEEEEECCCEECCCHHHH
AHYQAVGTAIGVPVMLYNNHAVSGIDMSVDLILRIVDAVDNVTMVKESTGDIQRMHQLYL
HHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHH
RTEGQLPFYNGSNPLALEAFAAGATGWCTAAANLIAADNIALYEAARQGRLVEARASFYR
HCCCCCCEECCCCCEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHCCCEEHHHHHHHH
QLPLLDFILKGGLPKTIKAGLEIAGVPVGAPRLPVKPLDEAGRARLSAILETLN
HCHHHHHHHHCCCCHHHHCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PDLAIQGIIGYTITPFDNQGRLDLNALDLTINRMIEAGVHAIAPLGSTGEGAYLSEEEW
CCCEEEEEECEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCHHH
TAVAERSVKTIAGRVPVIVSVSDLTTAGAVRRARAAESFGATAVMVLPTSYWKLQEDEIV
HHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHCCCEEEEEEECCCEECCCHHHH
AHYQAVGTAIGVPVMLYNNHAVSGIDMSVDLILRIVDAVDNVTMVKESTGDIQRMHQLYL
HHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHH
RTEGQLPFYNGSNPLALEAFAAGATGWCTAAANLIAADNIALYEAARQGRLVEARASFYR
HCCCCCCEECCCCCEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHCCCEEHHHHHHHH
QLPLLDFILKGGLPKTIKAGLEIAGVPVGAPRLPVKPLDEAGRARLSAILETLN
HCHHHHHHHHCCCCHHHHCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]