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The map label for this gene is fhuA [H]

Identifier: 75674923

GI number: 75674923

Start: 812692

End: 813231

Strand: Direct

Name: fhuA [H]

Synonym: Nwi_0726

Alternate gene names: 75674923

Gene position: 812692-813231 (Clockwise)

Preceding gene: 75674922

Following gene: 75674924

Centisome position: 23.89

GC content: 60.56

Gene sequence:

>540_bases
ATGAACCTGCGGATTACGGCCGCCATTTATGATCTGAGGCGCAAGAACGTTACGACACGGGATCCGGCGCACCCGTTCTT
CAGCATCCAGACCGGCGAGGTCACCGCGCGGGGTTTCGAATTCGAGGCCGTGACCAGCCTGACCAGTGGCCTGAGCCTTA
CGGGCGCTTACGCCTATAATGACGCCAGGGTGACCGAGAGCAATGACGCCAATCTGGGTATGCGCCCGATCCGAACTCCG
CAACATCTTGCATCGGTCTGGGCCAATTACACCATCCACGACGGCGCGCTGAACGGTCTTACCCTTGGCGGAGGCGTGCG
GTATGTGGGGGCGAGCGCAGGCGATTTCATGAATACGTTCTATGCGCCCGCCTATACGGTGGTGGATGCGATGGCCCGTT
ACGACATCGACAGCTGGCGCTTTTCCCTCAACGTCACCAACCTGTTCGATACGCAGTATGTCGCGGGGTGCGGGTATATC
GGCCAGTGTAACGTCGGACGCGTGCGCACCGTGCTCGGCAGGGTGAGCTATCGCTGGTAG

Upstream 100 bases:

>100_bases
AGTCCTTCATGCCCGTTTCTGGAACGACGTTTGACCAGGTGCCGTTCAGGCCGAAACCGGAACGCAGTACGAGGCAGGCG
TCAAATACCAGCCGCATGAT

Downstream 100 bases:

>100_bases
CGGACAGTGTTTGCGGCGGCGACGCCGGCTCGCCGCAGCAACCGAAGTATGTTTGTAGGCGGCGATAGATTCCCGGAGCA
GGTCGGCTTCGCTGAGTATG

Product: ferric siderophore receptor

Products: NA

Alternate protein names: Ferric hydroxamate receptor; Ferric hydroxamate uptake [H]

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MNLRITAAIYDLRRKNVTTRDPAHPFFSIQTGEVTARGFEFEAVTSLTSGLSLTGAYAYNDARVTESNDANLGMRPIRTP
QHLASVWANYTIHDGALNGLTLGGGVRYVGASAGDFMNTFYAPAYTVVDAMARYDIDSWRFSLNVTNLFDTQYVAGCGYI
GQCNVGRVRTVLGRVSYRW

Sequences:

>Translated_179_residues
MNLRITAAIYDLRRKNVTTRDPAHPFFSIQTGEVTARGFEFEAVTSLTSGLSLTGAYAYNDARVTESNDANLGMRPIRTP
QHLASVWANYTIHDGALNGLTLGGGVRYVGASAGDFMNTFYAPAYTVVDAMARYDIDSWRFSLNVTNLFDTQYVAGCGYI
GQCNVGRVRTVLGRVSYRW
>Mature_179_residues
MNLRITAAIYDLRRKNVTTRDPAHPFFSIQTGEVTARGFEFEAVTSLTSGLSLTGAYAYNDARVTESNDANLGMRPIRTP
QHLASVWANYTIHDGALNGLTLGGGVRYVGASAGDFMNTFYAPAYTVVDAMARYDIDSWRFSLNVTNLFDTQYVAGCGYI
GQCNVGRVRTVLGRVSYRW

Specific function: This receptor binds the ferrichrome-iron ligand. It interacts with the tonB protein, which is responsible for energy coupling of the ferrichrome-promoted iron transport system. Acts as a receptor for bacteriophage T5 as well as T1, phi80 and colicin M. Bi

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=180, Percent_Identity=42.2222222222222, Blast_Score=143, Evalue=7e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 19743; Mature: 19743

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLRITAAIYDLRRKNVTTRDPAHPFFSIQTGEVTARGFEFEAVTSLTSGLSLTGAYAYN
CCEEEEEHEEHHHHCCCCCCCCCCCEEEEECCCEEECCCCHHHHHHHHCCCEEEEEEEEC
DARVTESNDANLGMRPIRTPQHLASVWANYTIHDGALNGLTLGGGVRYVGASAGDFMNTF
CCEEECCCCCCCCCCCCCCHHHHHHHHHCCEEECCCCCCEEECCCEEEECCCCCHHHHHH
YAPAYTVVDAMARYDIDSWRFSLNVTNLFDTQYVAGCGYIGQCNVGRVRTVLGRVSYRW
HCHHHHHHHHHHHCCCCCEEEEEEEEEEECCHHHHCCCCCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MNLRITAAIYDLRRKNVTTRDPAHPFFSIQTGEVTARGFEFEAVTSLTSGLSLTGAYAYN
CCEEEEEHEEHHHHCCCCCCCCCCCEEEEECCCEEECCCCHHHHHHHHCCCEEEEEEEEC
DARVTESNDANLGMRPIRTPQHLASVWANYTIHDGALNGLTLGGGVRYVGASAGDFMNTF
CCEEECCCCCCCCCCCCCCHHHHHHHHHCCEEECCCCCCEEECCCEEEECCCCCHHHHHH
YAPAYTVVDAMARYDIDSWRFSLNVTNLFDTQYVAGCGYIGQCNVGRVRTVLGRVSYRW
HCHHHHHHHHHHHCCCCCEEEEEEEEEEECCHHHHCCCCCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3079747; 8202364; 9278503; 2823072; 7515827; 8617231; 9856937; 9865695; 10850805 [H]