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The map label for this gene is fhuA [H]

Identifier: 75674922

GI number: 75674922

Start: 810794

End: 812695

Strand: Direct

Name: fhuA [H]

Synonym: Nwi_0725

Alternate gene names: 75674922

Gene position: 810794-812695 (Clockwise)

Preceding gene: 75674921

Following gene: 75674923

Centisome position: 23.83

GC content: 60.57

Gene sequence:

>1902_bases
ATGGCGGGGCGGAGTGTTTCAGGAGTTGCGGCGATCAGGATGGCAAGGTTGCTGGCGTCGATATCGTTCGCCGCCTTGTT
GTTGCCGTCTCAAGCCGCATTCGCGCAAACCGCGCCGTCATCAGCGCCATCGGCGGGCGCGCTTCAACAGTCGATCACCT
TCGCCATTCCGCCGCAGTCCTTGTCGAGCGGCATCGTGGCGTTCTCGCGCGCGGCCGGAATCGATCTCGTTTTTGACGGC
GCGGTGCCGCGCGGCGCGCGCACGTCAGGCGTCTCTGGAACGTTCACGGTGCGCGACGGCGTCAACCGGTTGCTTGCGGG
CACCGGTCTGTCGGCGCGATTCACCAATGCGCGCACGGTGCAGATCGTCAACCCTTCCGCGGCGGGCGGCGTCAGCGGCG
CGGCTCCGTCAGGCGCGATCTCGCTCGACACCATCGACGTGCAGGGCGAGACCGCGTGGGGGCCGGCGAACGGTTTCGTC
GCCAGCCGCAGCGCCACCGCCACCAAGACCGATACGCCGATCATCGAGGTGCCGCAGTCGATTTCGGTGGTGACGCGAGA
TCAGATCGAGATACGGAGAAACCAGACCCTGAACGAGACGCTGCAATACACGCCGGGTGTTTTTGCCGAGTCGAGCGGCA
TGCAGCACAGTGGGCCGACGTTTCAGATACGAGGTTTCAGCGCCGTTCCCGCGGACGGGCCGATATTCCTGAACGGGTTG
CGCACGATCAATAACGGCGATATCGAGCCTTTCGGATTGGAGCGTATCGAAGTAATGCGCGGCCCGGCATCGGTTCTCTA
CGGGCAGAACCAGCCCAGCGGCGTGATCGCTCTCGTCACCAAGCGCCCGACGGAAGGACCCGTTCATGAAGTCCAGTTGC
GGGGCGGCAGTTTCGGCCAGAAGAGTGGCGCTTTCGACTTCGGCGGTCCGGTGACTGAGGACAGAACGCTGCTCTATCGC
TTCACCGGCCTGTTGCGGGAAGGCGGTAACGGCATTGATTTCTCAAACGATCAACGCGCGTTCGTTTCAGGCGCGGTGAC
GTGGCGCCCCACGGACGCGACAGAACTCACGGCGTTCAGCCTCTTTCAGAAAGACAAAGGCAGATGGAATTACGGCCTCC
CGGCGCAGGGAACGGCGCTGCCGAATCCGAACGGGCGAATCCCGGTTACGCGCTTCATCGGTGAGCCTGACCTTGACTAC
AATGTAACGGAACGGGCCGTCGTCGGATACAACCTTCAACATCGCGCCACCGAGAGCCTCACCTTCAGGCAGAATCTTCA
GTACGCGCGGGAAAACTGGGACTATCGCAACGCCACGCCGATCGGTCTTCAAGCCGACCTTCGTACGCTCGACCGTAGCT
ACGAAACCCTGCGTGCGAGTTGGGACACTTTTGCGATTGACAACCAGGCTGAACTGAAGACTACGACCGGCGTCCTGCAC
CACACCGTGCTGTTCGGTGTGGACTATCGATGGCGACGATACAATTCTCTTGGCTTATGGGGAGGAGTTGCTTCTCCGAT
CGATGTTTTTGCGCCTGTCTATGGCCAACCCGTTCTCATTTCGGCTGACAATTATGGATCTCGTCAAACTCAAAATTTCC
CCGGCATCTACCTTCAGGATCAGATCAAGCTCGACCGCTGGATCCTGACTTTCGGCGGACGCCACGATTGGGCGGAATCC
AAGACCGTCAATGCCTTTAGTGCTGCAGTCACCAATCAGAACGATCGGGCCTTCACTAGGCGGGCCGGGCTTGGCTACGA
ATTCGATAGCGGAGTGGTCCCTTACGTCAGCTATTCCGAGTCCTTCATGCCCGTTTCTGGAACGACGTTTGACCAGGTGC
CGTTCAGGCCGAAACCGGAACGCAGTACGAGGCAGGCGTCAAATACCAGCCGCATGATATGA

Upstream 100 bases:

>100_bases
TTTTCTCCGGTCCATCTGATACCGGCGGGATCGCTTCGTCTGAACGAGTGAGGAGCGCGGAATTAAGGCCGACGCTCATT
TGTTCAGGGGAGCGGGGGCG

Downstream 100 bases:

>100_bases
ACCTGCGGATTACGGCCGCCATTTATGATCTGAGGCGCAAGAACGTTACGACACGGGATCCGGCGCACCCGTTCTTCAGC
ATCCAGACCGGCGAGGTCAC

Product: TonB-dependent receptor protein

Products: NA

Alternate protein names: Ferric hydroxamate receptor; Ferric hydroxamate uptake [H]

Number of amino acids: Translated: 633; Mature: 632

Protein sequence:

>633_residues
MAGRSVSGVAAIRMARLLASISFAALLLPSQAAFAQTAPSSAPSAGALQQSITFAIPPQSLSSGIVAFSRAAGIDLVFDG
AVPRGARTSGVSGTFTVRDGVNRLLAGTGLSARFTNARTVQIVNPSAAGGVSGAAPSGAISLDTIDVQGETAWGPANGFV
ASRSATATKTDTPIIEVPQSISVVTRDQIEIRRNQTLNETLQYTPGVFAESSGMQHSGPTFQIRGFSAVPADGPIFLNGL
RTINNGDIEPFGLERIEVMRGPASVLYGQNQPSGVIALVTKRPTEGPVHEVQLRGGSFGQKSGAFDFGGPVTEDRTLLYR
FTGLLREGGNGIDFSNDQRAFVSGAVTWRPTDATELTAFSLFQKDKGRWNYGLPAQGTALPNPNGRIPVTRFIGEPDLDY
NVTERAVVGYNLQHRATESLTFRQNLQYARENWDYRNATPIGLQADLRTLDRSYETLRASWDTFAIDNQAELKTTTGVLH
HTVLFGVDYRWRRYNSLGLWGGVASPIDVFAPVYGQPVLISADNYGSRQTQNFPGIYLQDQIKLDRWILTFGGRHDWAES
KTVNAFSAAVTNQNDRAFTRRAGLGYEFDSGVVPYVSYSESFMPVSGTTFDQVPFRPKPERSTRQASNTSRMI

Sequences:

>Translated_633_residues
MAGRSVSGVAAIRMARLLASISFAALLLPSQAAFAQTAPSSAPSAGALQQSITFAIPPQSLSSGIVAFSRAAGIDLVFDG
AVPRGARTSGVSGTFTVRDGVNRLLAGTGLSARFTNARTVQIVNPSAAGGVSGAAPSGAISLDTIDVQGETAWGPANGFV
ASRSATATKTDTPIIEVPQSISVVTRDQIEIRRNQTLNETLQYTPGVFAESSGMQHSGPTFQIRGFSAVPADGPIFLNGL
RTINNGDIEPFGLERIEVMRGPASVLYGQNQPSGVIALVTKRPTEGPVHEVQLRGGSFGQKSGAFDFGGPVTEDRTLLYR
FTGLLREGGNGIDFSNDQRAFVSGAVTWRPTDATELTAFSLFQKDKGRWNYGLPAQGTALPNPNGRIPVTRFIGEPDLDY
NVTERAVVGYNLQHRATESLTFRQNLQYARENWDYRNATPIGLQADLRTLDRSYETLRASWDTFAIDNQAELKTTTGVLH
HTVLFGVDYRWRRYNSLGLWGGVASPIDVFAPVYGQPVLISADNYGSRQTQNFPGIYLQDQIKLDRWILTFGGRHDWAES
KTVNAFSAAVTNQNDRAFTRRAGLGYEFDSGVVPYVSYSESFMPVSGTTFDQVPFRPKPERSTRQASNTSRMI
>Mature_632_residues
AGRSVSGVAAIRMARLLASISFAALLLPSQAAFAQTAPSSAPSAGALQQSITFAIPPQSLSSGIVAFSRAAGIDLVFDGA
VPRGARTSGVSGTFTVRDGVNRLLAGTGLSARFTNARTVQIVNPSAAGGVSGAAPSGAISLDTIDVQGETAWGPANGFVA
SRSATATKTDTPIIEVPQSISVVTRDQIEIRRNQTLNETLQYTPGVFAESSGMQHSGPTFQIRGFSAVPADGPIFLNGLR
TINNGDIEPFGLERIEVMRGPASVLYGQNQPSGVIALVTKRPTEGPVHEVQLRGGSFGQKSGAFDFGGPVTEDRTLLYRF
TGLLREGGNGIDFSNDQRAFVSGAVTWRPTDATELTAFSLFQKDKGRWNYGLPAQGTALPNPNGRIPVTRFIGEPDLDYN
VTERAVVGYNLQHRATESLTFRQNLQYARENWDYRNATPIGLQADLRTLDRSYETLRASWDTFAIDNQAELKTTTGVLHH
TVLFGVDYRWRRYNSLGLWGGVASPIDVFAPVYGQPVLISADNYGSRQTQNFPGIYLQDQIKLDRWILTFGGRHDWAESK
TVNAFSAAVTNQNDRAFTRRAGLGYEFDSGVVPYVSYSESFMPVSGTTFDQVPFRPKPERSTRQASNTSRMI

Specific function: This receptor binds the ferrichrome-iron ligand. It interacts with the tonB protein, which is responsible for energy coupling of the ferrichrome-promoted iron transport system. Acts as a receptor for bacteriophage T5 as well as T1, phi80 and colicin M. Bi

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=537, Percent_Identity=35.9404096834264, Blast_Score=287, Evalue=1e-78,
Organism=Escherichia coli, GI1787344, Length=270, Percent_Identity=27.037037037037, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1787024, Length=364, Percent_Identity=21.4285714285714, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788478, Length=209, Percent_Identity=27.2727272727273, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 68374; Mature: 68243

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGRSVSGVAAIRMARLLASISFAALLLPSQAAFAQTAPSSAPSAGALQQSITFAIPPQS
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCHHHHCCEEEECCHH
LSSGIVAFSRAAGIDLVFDGAVPRGARTSGVSGTFTVRDGVNRLLAGTGLSARFTNARTV
HHCCCEEEHHCCCEEEEECCCCCCCCCCCCCCEEEEEHHHHHHHHHCCCCCEEECCCEEE
QIVNPSAAGGVSGAAPSGAISLDTIDVQGETAWGPANGFVASRSATATKTDTPIIEVPQS
EEECCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCEEECCCCCCCCCCCCEEECCCC
ISVVTRDQIEIRRNQTLNETLQYTPGVFAESSGMQHSGPTFQIRGFSAVPADGPIFLNGL
CEEEECCHHHHHCCCCHHHHHHCCCCCEECCCCCCCCCCEEEEECEEECCCCCCEEEECE
RTINNGDIEPFGLERIEVMRGPASVLYGQNQPSGVIALVTKRPTEGPVHEVQLRGGSFGQ
EECCCCCCCCCCCCHHEECCCCHHEEECCCCCCCEEEEEEECCCCCCCEEEEECCCCCCC
KSGAFDFGGPVTEDRTLLYRFTGLLREGGNGIDFSNDQRAFVSGAVTWRPTDATELTAFS
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHH
LFQKDKGRWNYGLPAQGTALPNPNGRIPVTRFIGEPDLDYNVTERAVVGYNLQHRATESL
HHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEECCCHHHHHHHH
TFRQNLQYARENWDYRNATPIGLQADLRTLDRSYETLRASWDTFAIDNQAELKTTTGVLH
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHH
HTVLFGVDYRWRRYNSLGLWGGVASPIDVFAPVYGQPVLISADNYGSRQTQNFPGIYLQD
EEEEEECCCCEEEECCCEECCCCCCCHHHHHHCCCCEEEEECCCCCCCCCCCCCCEEEEE
QIKLDRWILTFGGRHDWAESKTVNAFSAAVTNQNDRAFTRRAGLGYEFDSGVVPYVSYSE
CEEEEEEEEEECCCCCCCCCCCCCHHHHEECCCCCHHHHHHCCCCEECCCCCCCEEECCC
SFMPVSGTTFDQVPFRPKPERSTRQASNTSRMI
CEECCCCCCCCCCCCCCCCCHHHHHHCCCCCCC
>Mature Secondary Structure 
AGRSVSGVAAIRMARLLASISFAALLLPSQAAFAQTAPSSAPSAGALQQSITFAIPPQS
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCHHHHCCEEEECCHH
LSSGIVAFSRAAGIDLVFDGAVPRGARTSGVSGTFTVRDGVNRLLAGTGLSARFTNARTV
HHCCCEEEHHCCCEEEEECCCCCCCCCCCCCCEEEEEHHHHHHHHHCCCCCEEECCCEEE
QIVNPSAAGGVSGAAPSGAISLDTIDVQGETAWGPANGFVASRSATATKTDTPIIEVPQS
EEECCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCEEECCCCCCCCCCCCEEECCCC
ISVVTRDQIEIRRNQTLNETLQYTPGVFAESSGMQHSGPTFQIRGFSAVPADGPIFLNGL
CEEEECCHHHHHCCCCHHHHHHCCCCCEECCCCCCCCCCEEEEECEEECCCCCCEEEECE
RTINNGDIEPFGLERIEVMRGPASVLYGQNQPSGVIALVTKRPTEGPVHEVQLRGGSFGQ
EECCCCCCCCCCCCHHEECCCCHHEEECCCCCCCEEEEEEECCCCCCCEEEEECCCCCCC
KSGAFDFGGPVTEDRTLLYRFTGLLREGGNGIDFSNDQRAFVSGAVTWRPTDATELTAFS
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHH
LFQKDKGRWNYGLPAQGTALPNPNGRIPVTRFIGEPDLDYNVTERAVVGYNLQHRATESL
HHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEECCCHHHHHHHH
TFRQNLQYARENWDYRNATPIGLQADLRTLDRSYETLRASWDTFAIDNQAELKTTTGVLH
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHH
HTVLFGVDYRWRRYNSLGLWGGVASPIDVFAPVYGQPVLISADNYGSRQTQNFPGIYLQD
EEEEEECCCCEEEECCCEECCCCCCCHHHHHHCCCCEEEEECCCCCCCCCCCCCCEEEEE
QIKLDRWILTFGGRHDWAESKTVNAFSAAVTNQNDRAFTRRAGLGYEFDSGVVPYVSYSE
CEEEEEEEEEECCCCCCCCCCCCCHHHHEECCCCCHHHHHHCCCCEECCCCCCCEEECCC
SFMPVSGTTFDQVPFRPKPERSTRQASNTSRMI
CEECCCCCCCCCCCCCCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3079747; 8202364; 9278503; 2823072; 7515827; 8617231; 9856937; 9865695; 10850805 [H]