Click here to switch to the map view.

The map label for this gene is yugS [H]

Identifier: 75674595

GI number: 75674595

Start: 444451

End: 445800

Strand: Direct

Name: yugS [H]

Synonym: Nwi_0397

Alternate gene names: 75674595

Gene position: 444451-445800 (Clockwise)

Preceding gene: 75674594

Following gene: 75674599

Centisome position: 13.06

GC content: 63.41

Gene sequence:

>1350_bases
ATGAGTTCAACTCTCCAGATACTGCTCGCCGTGCTGCTGCTGGCCGCCAACGGGTTCTTCGTCGCGGCGGAGTTCGCGCT
GGTGAAAAGCCGCGGCTACCGCGTCAAGGCGATGGTGGAACGCGGTCAGTTCGGCGCGCGGCTGATGCGCGACATCATGG
GCAACATCGAGGCCTATCTCGCCTGCTGCCAGCTCGGCATCACCATGGCGTCGCTCGGCCTCGGCTGGGTCGGCGAGCCA
ACGGTGGAGGCGCTGCTCGCCCCCCTGCTGCGGCCGCTCGGCATGCCGGAACCGGCGCTGCATTTGACCGCCTTCCTGAC
CGGGTTTCTTGTATTCTCGTCGCTGCACATCGTGATCGGCGAGCAGGTGCCGAAAACGCTGGCGATCCGGCAGCCGGAGC
CGGTGTCGCAGTGGATCATCTATCCGCTCCATGCCTCCTATGTCCTGTTTTATCCGCTGAACTGGCTGCTCAATTCGGCC
TCGCGCGCCATCCTGCGCGCGCTTCGCGTCAAGGAAGTCTCGCAGCATGACGTGTTGACCGGCGCGGAAATCGAAGGGCT
GATCGGTGAATCCGCCGAGCATGGCGGAATCGAAAGCGGCGAGGCCGAATACATCCAGAATGTGTTCCGCTTCGGCGACC
TCGCGGTGTCGGACGTGATGGTTCATCGCACCGCGATGGTGACGATCAACGCCGATTTGCCTCCGGAGGATCTGGTGCGC
GAGGTGCTTGCCAGCGAATACACCCGCATCCCGCTCTGGCGCGACAAGCCGGAGAACATTGTCGGCGTGCTCCATGCCAA
GGATCTGCTGCGGGCGATTCATGCCTCGGAGGGCGATATAGCCCGCATCAACGTCAACGCGATCGCGCTGCCGCCCTGGT
TCGTGCCGGAGATGCGTCCCGTTTCCGATCAGCTCAAGGCGTTTCGCCGCCGCAAGACTCACTTCGCGCTGGTGGTCGAC
GAATACGGTGAAGTCGAGGGCATGGTGACGCTGGAAGACGTTCTCGAGGAGATCGTCGGCGATATCTCCGATGAGCACGA
CGTGGTTGTCGCCGGCGTTCGGCAGCAGGCCGACGGCTCGGTGGTGGTGGATGGTTCGGTGCCGATCCGCGATCTCAATC
GCGCTATGGACTGGCATCTTCCGGACGAGGAAGCGACCACCATCGCGGGCCTCGTGATTCATGAGGCGCGTTCGATCCCC
GAGCGGGGTCAGAATTTTACCTTCTACGGTTTTCGCTTCAGGGTTTTGCGGCGCGAGCGCAACCGCATCACGGCGCTGCG
CATTCAGCCGGTGCCGCGCGGAGGGGAGGCGATCGAGAACAGGCCGAAACGCACGGGAATGTTGTCCTGA

Upstream 100 bases:

>100_bases
GCTGAAGGCGATCGGTCAGGCGGTGGTGTCGTCGGACGTCGAGCCGTCGATGGTTCGGGATTTTCTCGCCCGCAAGCTGG
CGGACGCGCCGGCCTAGACG

Downstream 100 bases:

>100_bases
CGAGCGCGGGAGTTTCGCGATCGCTGGCGGCTGTGCGTTTCTGACTCGATCAGTAGCGCGGGCGCTATGGCGTTTTCAAG
CGAACAAGATAGCGGATCAG

Product: Mg2+ and Co2+ transporter CorB family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MSSTLQILLAVLLLAANGFFVAAEFALVKSRGYRVKAMVERGQFGARLMRDIMGNIEAYLACCQLGITMASLGLGWVGEP
TVEALLAPLLRPLGMPEPALHLTAFLTGFLVFSSLHIVIGEQVPKTLAIRQPEPVSQWIIYPLHASYVLFYPLNWLLNSA
SRAILRALRVKEVSQHDVLTGAEIEGLIGESAEHGGIESGEAEYIQNVFRFGDLAVSDVMVHRTAMVTINADLPPEDLVR
EVLASEYTRIPLWRDKPENIVGVLHAKDLLRAIHASEGDIARINVNAIALPPWFVPEMRPVSDQLKAFRRRKTHFALVVD
EYGEVEGMVTLEDVLEEIVGDISDEHDVVVAGVRQQADGSVVVDGSVPIRDLNRAMDWHLPDEEATTIAGLVIHEARSIP
ERGQNFTFYGFRFRVLRRERNRITALRIQPVPRGGEAIENRPKRTGMLS

Sequences:

>Translated_449_residues
MSSTLQILLAVLLLAANGFFVAAEFALVKSRGYRVKAMVERGQFGARLMRDIMGNIEAYLACCQLGITMASLGLGWVGEP
TVEALLAPLLRPLGMPEPALHLTAFLTGFLVFSSLHIVIGEQVPKTLAIRQPEPVSQWIIYPLHASYVLFYPLNWLLNSA
SRAILRALRVKEVSQHDVLTGAEIEGLIGESAEHGGIESGEAEYIQNVFRFGDLAVSDVMVHRTAMVTINADLPPEDLVR
EVLASEYTRIPLWRDKPENIVGVLHAKDLLRAIHASEGDIARINVNAIALPPWFVPEMRPVSDQLKAFRRRKTHFALVVD
EYGEVEGMVTLEDVLEEIVGDISDEHDVVVAGVRQQADGSVVVDGSVPIRDLNRAMDWHLPDEEATTIAGLVIHEARSIP
ERGQNFTFYGFRFRVLRRERNRITALRIQPVPRGGEAIENRPKRTGMLS
>Mature_448_residues
SSTLQILLAVLLLAANGFFVAAEFALVKSRGYRVKAMVERGQFGARLMRDIMGNIEAYLACCQLGITMASLGLGWVGEPT
VEALLAPLLRPLGMPEPALHLTAFLTGFLVFSSLHIVIGEQVPKTLAIRQPEPVSQWIIYPLHASYVLFYPLNWLLNSAS
RAILRALRVKEVSQHDVLTGAEIEGLIGESAEHGGIESGEAEYIQNVFRFGDLAVSDVMVHRTAMVTINADLPPEDLVRE
VLASEYTRIPLWRDKPENIVGVLHAKDLLRAIHASEGDIARINVNAIALPPWFVPEMRPVSDQLKAFRRRKTHFALVVDE
YGEVEGMVTLEDVLEEIVGDISDEHDVVVAGVRQQADGSVVVDGSVPIRDLNRAMDWHLPDEEATTIAGLVIHEARSIPE
RGQNFTFYGFRFRVLRRERNRITALRIQPVPRGGEAIENRPKRTGMLS

Specific function: Unknown

COG id: COG4536

COG function: function code P; Putative Mg2+ and Co2+ transporter CorB

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=414, Percent_Identity=35.024154589372, Blast_Score=252, Evalue=4e-67,
Organism=Homo sapiens, GI94681046, Length=242, Percent_Identity=25.6198347107438, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI145693175, Length=419, Percent_Identity=28.4009546539379, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1790664, Length=439, Percent_Identity=24.6013667425968, Blast_Score=151, Evalue=7e-38,
Organism=Escherichia coli, GI1786879, Length=260, Percent_Identity=29.6153846153846, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI87082033, Length=273, Percent_Identity=29.3040293040293, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1788119, Length=236, Percent_Identity=28.3898305084746, Blast_Score=76, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 49840; Mature: 49709

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTLQILLAVLLLAANGFFVAAEFALVKSRGYRVKAMVERGQFGARLMRDIMGNIEAYL
CCHHHHHHHHHHHHHCCCCEEEHHHHHHHCCCCEEEEEHHCCHHHHHHHHHHHHHHHHHH
ACCQLGITMASLGLGWVGEPTVEALLAPLLRPLGMPEPALHLTAFLTGFLVFSSLHIVIG
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEC
EQVPKTLAIRQPEPVSQWIIYPLHASYVLFYPLNWLLNSASRAILRALRVKEVSQHDVLT
CCCCCCEECCCCCCCHHHEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GAEIEGLIGESAEHGGIESGEAEYIQNVFRFGDLAVSDVMVHRTAMVTINADLPPEDLVR
CCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHEEEEEEEEECCCCHHHHHH
EVLASEYTRIPLWRDKPENIVGVLHAKDLLRAIHASEGDIARINVNAIALPPWFVPEMRP
HHHHHHHHCCCCCCCCCCHHEEHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCCCCC
VSDQLKAFRRRKTHFALVVDEYGEVEGMVTLEDVLEEIVGDISDEHDVVVAGVRQQADGS
HHHHHHHHHHCCCEEEEEEECCCCCCCEEEHHHHHHHHHHCCCCCCCEEEEECCCCCCCC
VVVDGSVPIRDLNRAMDWHLPDEEATTIAGLVIHEARSIPERGQNFTFYGFRFRVLRRER
EEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHC
NRITALRIQPVPRGGEAIENRPKRTGMLS
CCEEEEEEEECCCCCHHHHCCCCCCCCCC
>Mature Secondary Structure 
SSTLQILLAVLLLAANGFFVAAEFALVKSRGYRVKAMVERGQFGARLMRDIMGNIEAYL
CHHHHHHHHHHHHHCCCCEEEHHHHHHHCCCCEEEEEHHCCHHHHHHHHHHHHHHHHHH
ACCQLGITMASLGLGWVGEPTVEALLAPLLRPLGMPEPALHLTAFLTGFLVFSSLHIVIG
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEC
EQVPKTLAIRQPEPVSQWIIYPLHASYVLFYPLNWLLNSASRAILRALRVKEVSQHDVLT
CCCCCCEECCCCCCCHHHEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GAEIEGLIGESAEHGGIESGEAEYIQNVFRFGDLAVSDVMVHRTAMVTINADLPPEDLVR
CCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHEEEEEEEEECCCCHHHHHH
EVLASEYTRIPLWRDKPENIVGVLHAKDLLRAIHASEGDIARINVNAIALPPWFVPEMRP
HHHHHHHHCCCCCCCCCCHHEEHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCCCCC
VSDQLKAFRRRKTHFALVVDEYGEVEGMVTLEDVLEEIVGDISDEHDVVVAGVRQQADGS
HHHHHHHHHHCCCEEEEEEECCCCCCCEEEHHHHHHHHHHCCCCCCCEEEEECCCCCCCC
VVVDGSVPIRDLNRAMDWHLPDEEATTIAGLVIHEARSIPERGQNFTFYGFRFRVLRRER
EEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHC
NRITALRIQPVPRGGEAIENRPKRTGMLS
CCEEEEEEEECCCCCHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377 [H]