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The map label for this gene is aroB [H]

Identifier: 75674594

GI number: 75674594

Start: 443296

End: 444447

Strand: Direct

Name: aroB [H]

Synonym: Nwi_0396

Alternate gene names: 75674594

Gene position: 443296-444447 (Clockwise)

Preceding gene: 75674593

Following gene: 75674595

Centisome position: 13.03

GC content: 66.15

Gene sequence:

>1152_bases
ATGACCATTCCGATCAAAGAATCAGACCCGATCACGGTCGATGTCGCGCTCGGTGAGCGCTCCTACGACATTGTCATCGG
ACGAGGCGTCCTGCCGTCGCTGGGCGAGCGGATCGCCGCGTTGCGTCCCGGCGCGCGCGTCGCCGTCGTCACCGACGCCC
GTGTCGCCACCCATTGGCTTCAGCGAACCGAGGCATCGCTGACCGGCGCCGGTCTTACAACCTCGCGGATCGTCGTCGAC
GAAGGCGAGGTTTCGAAGAGCTACGCGGGCGTTGAATTTGTCTGTGAGGAACTGATCAAGGCCAGAATCGAGCGCAACGA
TCTTGTGGTCGCGCTTGGCGGCGGCGTGGTCGGCGATCTCGCGGGCTTCGCCGCCGCGATCGTACGCCGTGGTGTCGATT
TCGTGCAGGTGCCGACGTCGCTGCTGGCGCAGGTGGATTCGTCCGTGGGCGGCAAGACCGGCATCAACTCGCCGCAGGGC
AAGAATCTGGTCGGCGCCTTTCACCAGCCGATCCTGGTGGTGGCGGACACCGCCGTGCTGGATACCTTGTCGCCGCGCCA
GTTTCGCGCCGGTTATGCCGAAGTCGCCAAATACGGACTGATCGGCGATGAGGCGTTCTTCGCGTGGCTGGAGGTCCACC
ATGCCGATATCGTCAAGGGTGATGCGGCGCGCGAGCACGCGGTCGCCACCAGTTGCCGCGCCAAGGCTGCCATCGTCGCC
CGCGACGAGCGCGAGAGCGGCGAGCGCGCGTTGCTCAATCTCGGTCATACCTTCGGCCACGCGCTGGAAGCGGCGACCGG
ATTTTGCGGGCGCCTTTATCACGGCGAGGGTGTTTCGATCGGCATGGTGCTGGCCGCCGAACTCTCGGCGCAGCTCGGAA
TGATAGCGGCCGCCGACGTGTCCCGTATCGAGAGGCATCTGGCGGCGGCGGGTCTGCCGACGCGCTTGCAGGACATCGCC
GGCTTCAGGCAGGAGGGCCTGGCCGATGCGGATGCGCTGATGACGCTGATGGCGCAGGACAAGAAGGTCAGGCGCGGCCG
GCTGACCTTCATCCTGCTGAAGGCGATCGGTCAGGCGGTGGTGTCGTCGGACGTCGAGCCGTCGATGGTTCGGGATTTTC
TCGCCCGCAAGCTGGCGGACGCGCCGGCCTAG

Upstream 100 bases:

>100_bases
TCGTCGATGAATGCATCGGCCTGCTTCATCGCAGGCTTTGCCGCGGCGAAATGACTCGAAATGCGATGAAAGACCCTGAC
GAGGGATTTGACACCACGCA

Downstream 100 bases:

>100_bases
ACGATGAGTTCAACTCTCCAGATACTGCTCGCCGTGCTGCTGCTGGCCGCCAACGGGTTCTTCGTCGCGGCGGAGTTCGC
GCTGGTGAAAAGCCGCGGCT

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MTIPIKESDPITVDVALGERSYDIVIGRGVLPSLGERIAALRPGARVAVVTDARVATHWLQRTEASLTGAGLTTSRIVVD
EGEVSKSYAGVEFVCEELIKARIERNDLVVALGGGVVGDLAGFAAAIVRRGVDFVQVPTSLLAQVDSSVGGKTGINSPQG
KNLVGAFHQPILVVADTAVLDTLSPRQFRAGYAEVAKYGLIGDEAFFAWLEVHHADIVKGDAAREHAVATSCRAKAAIVA
RDERESGERALLNLGHTFGHALEAATGFCGRLYHGEGVSIGMVLAAELSAQLGMIAAADVSRIERHLAAAGLPTRLQDIA
GFRQEGLADADALMTLMAQDKKVRRGRLTFILLKAIGQAVVSSDVEPSMVRDFLARKLADAPA

Sequences:

>Translated_383_residues
MTIPIKESDPITVDVALGERSYDIVIGRGVLPSLGERIAALRPGARVAVVTDARVATHWLQRTEASLTGAGLTTSRIVVD
EGEVSKSYAGVEFVCEELIKARIERNDLVVALGGGVVGDLAGFAAAIVRRGVDFVQVPTSLLAQVDSSVGGKTGINSPQG
KNLVGAFHQPILVVADTAVLDTLSPRQFRAGYAEVAKYGLIGDEAFFAWLEVHHADIVKGDAAREHAVATSCRAKAAIVA
RDERESGERALLNLGHTFGHALEAATGFCGRLYHGEGVSIGMVLAAELSAQLGMIAAADVSRIERHLAAAGLPTRLQDIA
GFRQEGLADADALMTLMAQDKKVRRGRLTFILLKAIGQAVVSSDVEPSMVRDFLARKLADAPA
>Mature_382_residues
TIPIKESDPITVDVALGERSYDIVIGRGVLPSLGERIAALRPGARVAVVTDARVATHWLQRTEASLTGAGLTTSRIVVDE
GEVSKSYAGVEFVCEELIKARIERNDLVVALGGGVVGDLAGFAAAIVRRGVDFVQVPTSLLAQVDSSVGGKTGINSPQGK
NLVGAFHQPILVVADTAVLDTLSPRQFRAGYAEVAKYGLIGDEAFFAWLEVHHADIVKGDAAREHAVATSCRAKAAIVAR
DERESGERALLNLGHTFGHALEAATGFCGRLYHGEGVSIGMVLAAELSAQLGMIAAADVSRIERHLAAAGLPTRLQDIAG
FRQEGLADADALMTLMAQDKKVRRGRLTFILLKAIGQAVVSSDVEPSMVRDFLARKLADAPA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=362, Percent_Identity=45.8563535911602, Blast_Score=267, Evalue=8e-73,
Organism=Saccharomyces cerevisiae, GI6320332, Length=344, Percent_Identity=38.0813953488372, Blast_Score=188, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 40416; Mature: 40285

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIPIKESDPITVDVALGERSYDIVIGRGVLPSLGERIAALRPGARVAVVTDARVATHWL
CCCCCCCCCCEEEEEEECCCCEEEEEECCCCHHHHHHHHHCCCCCEEEEEECHHHHHHHH
QRTEASLTGAGLTTSRIVVDEGEVSKSYAGVEFVCEELIKARIERNDLVVALGGGVVGDL
HHHHCCCCCCCCEEEEEEEECCCCCHHHCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHH
AGFAAAIVRRGVDFVQVPTSLLAQVDSSVGGKTGINSPQGKNLVGAFHQPILVVADTAVL
HHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCEEEEECHHHH
DTLSPRQFRAGYAEVAKYGLIGDEAFFAWLEVHHADIVKGDAAREHAVATSCRAKAAIVA
HCCCCHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCEEEEE
RDERESGERALLNLGHTFGHALEAATGFCGRLYHGEGVSIGMVLAAELSAQLGMIAAADV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEHHHHHHHHHHHHHHHHHHHH
SRIERHLAAAGLPTRLQDIAGFRQEGLADADALMTLMAQDKKVRRGRLTFILLKAIGQAV
HHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSSDVEPSMVRDFLARKLADAPA
HHCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TIPIKESDPITVDVALGERSYDIVIGRGVLPSLGERIAALRPGARVAVVTDARVATHWL
CCCCCCCCCEEEEEEECCCCEEEEEECCCCHHHHHHHHHCCCCCEEEEEECHHHHHHHH
QRTEASLTGAGLTTSRIVVDEGEVSKSYAGVEFVCEELIKARIERNDLVVALGGGVVGDL
HHHHCCCCCCCCEEEEEEEECCCCCHHHCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHH
AGFAAAIVRRGVDFVQVPTSLLAQVDSSVGGKTGINSPQGKNLVGAFHQPILVVADTAVL
HHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCEEEEECHHHH
DTLSPRQFRAGYAEVAKYGLIGDEAFFAWLEVHHADIVKGDAAREHAVATSCRAKAAIVA
HCCCCHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCEEEEE
RDERESGERALLNLGHTFGHALEAATGFCGRLYHGEGVSIGMVLAAELSAQLGMIAAADV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEHHHHHHHHHHHHHHHHHHHH
SRIERHLAAAGLPTRLQDIAGFRQEGLADADALMTLMAQDKKVRRGRLTFILLKAIGQAV
HHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSSDVEPSMVRDFLARKLADAPA
HHCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA