| Definition | Thiobacillus denitrificans ATCC 25259 chromosome, complete genome. |
|---|---|
| Accession | NC_007404 |
| Length | 2,909,809 |
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The map label for this gene is fabG [H]
Identifier: 74318774
GI number: 74318774
Start: 2835200
End: 2835919
Strand: Direct
Name: fabG [H]
Synonym: Tbd_2756
Alternate gene names: 74318774
Gene position: 2835200-2835919 (Clockwise)
Preceding gene: 74318773
Following gene: 74318775
Centisome position: 97.44
GC content: 70.0
Gene sequence:
>720_bases ATGAAACGCGCACTCGTGACCGGCGGCAGCGGCGGCATCGGCGCCGCGATCTGCCGGCGACTCGCCGCCGACAGCTGCCA CGTCTACGTCCACGCCAACCGGAATCTCGCCAGGGCGAGCGCGCTCGCCGACGAAATCCGCGCGGCCGGCGGCGCGGCCG AAGCCGTCAGTTTCGACGTCACCGATGTCGCGGCATGCCGCGCGACGCTCGAGGCGCTGGTCGAGAGCGAGCCGATCCAG ATCCTCGTCAACAATGCCGGCATCCACGACGACGCGGTATTCCCGGGGATGCGCGCCGAACAGTGGCATCGCGTGCTCGA CGTCTCGCTCAACGGCTTCTTCAACGTGACCCAGCCGCTGACGCTGCCGATGATCCGCAGCCGCTGGGGGCGCATCGTCA ACATCACCTCGGTCGCCGGGCTCACCGGCAACCGCGGGCAGGCCAACTACGCCGCGGCCAAGGGCGCGCTGCACGCCGCG ACCAAATCGCTTTCGCTCGAACTCGCGAGCCGCGGCGTGACCGTCAACGCGGTCGCGCCGGGCGTGATCCGCACCGCGAT GAGCGACGGCGTCTTCGACGACGCGTCCATCGCGGCGCTGGTGCCGATGAAGCGCGCCGGGCAGCCCGAAGACGTCGCCA GCGCCGTCGCATTCCTCGCCTCGGACCAGGCGAGCTACATCAGCGGGCAGGTGCTGTCGGTCAACGGAGGCATGATCTGA
Upstream 100 bases:
>100_bases ACACGATCCTTTACCGTTTCAGCGTCGCCGGGCCGACCGGCCTGCTCGTGAGCGGACGCGCGATCGTCATGCTCGACGCT GAAAAAACCCGGAGTCCCCT
Downstream 100 bases:
>100_bases ACGACGCCACCCGCGCGCTCGCCGTGCATCAGAGCGAAGCGCTGCTGTTCTTCACCCTGCTTCAACTGACCGTAATCGTG CTCGCCGCGCGCGCCGGCGG
Product: 3-ketoacyl-(acyl-carrier-protein) reductase
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 239; Mature: 239
Protein sequence:
>239_residues MKRALVTGGSGGIGAAICRRLAADSCHVYVHANRNLARASALADEIRAAGGAAEAVSFDVTDVAACRATLEALVESEPIQ ILVNNAGIHDDAVFPGMRAEQWHRVLDVSLNGFFNVTQPLTLPMIRSRWGRIVNITSVAGLTGNRGQANYAAAKGALHAA TKSLSLELASRGVTVNAVAPGVIRTAMSDGVFDDASIAALVPMKRAGQPEDVASAVAFLASDQASYISGQVLSVNGGMI
Sequences:
>Translated_239_residues MKRALVTGGSGGIGAAICRRLAADSCHVYVHANRNLARASALADEIRAAGGAAEAVSFDVTDVAACRATLEALVESEPIQ ILVNNAGIHDDAVFPGMRAEQWHRVLDVSLNGFFNVTQPLTLPMIRSRWGRIVNITSVAGLTGNRGQANYAAAKGALHAA TKSLSLELASRGVTVNAVAPGVIRTAMSDGVFDDASIAALVPMKRAGQPEDVASAVAFLASDQASYISGQVLSVNGGMI >Mature_239_residues MKRALVTGGSGGIGAAICRRLAADSCHVYVHANRNLARASALADEIRAAGGAAEAVSFDVTDVAACRATLEALVESEPIQ ILVNNAGIHDDAVFPGMRAEQWHRVLDVSLNGFFNVTQPLTLPMIRSRWGRIVNITSVAGLTGNRGQANYAAAKGALHAA TKSLSLELASRGVTVNAVAPGVIRTAMSDGVFDDASIAALVPMKRAGQPEDVASAVAFLASDQASYISGQVLSVNGGMI
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=251, Percent_Identity=37.0517928286853, Blast_Score=133, Evalue=1e-31, Organism=Homo sapiens, GI40254992, Length=234, Percent_Identity=35.4700854700855, Blast_Score=114, Evalue=1e-25, Organism=Homo sapiens, GI32483357, Length=248, Percent_Identity=33.8709677419355, Blast_Score=112, Evalue=2e-25, Organism=Homo sapiens, GI19923817, Length=247, Percent_Identity=34.412955465587, Blast_Score=104, Evalue=7e-23, Organism=Homo sapiens, GI10190704, Length=245, Percent_Identity=33.0612244897959, Blast_Score=97, Evalue=9e-21, Organism=Homo sapiens, GI7705925, Length=242, Percent_Identity=30.9917355371901, Blast_Score=93, Evalue=2e-19, Organism=Homo sapiens, GI5031737, Length=242, Percent_Identity=31.8181818181818, Blast_Score=92, Evalue=6e-19, Organism=Homo sapiens, GI126723750, Length=245, Percent_Identity=28.9795918367347, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI59889578, Length=174, Percent_Identity=35.0574712643678, Blast_Score=89, Evalue=4e-18, Organism=Homo sapiens, GI4504505, Length=243, Percent_Identity=31.6872427983539, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI4503301, Length=218, Percent_Identity=30.7339449541284, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI4758504, Length=258, Percent_Identity=28.2945736434109, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI33667109, Length=191, Percent_Identity=31.9371727748691, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI7657478, Length=205, Percent_Identity=28.780487804878, Blast_Score=68, Evalue=9e-12, Organism=Homo sapiens, GI150247226, Length=196, Percent_Identity=32.1428571428571, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI223718074, Length=193, Percent_Identity=31.0880829015544, Blast_Score=64, Evalue=8e-11, Organism=Escherichia coli, GI1787335, Length=240, Percent_Identity=45.8333333333333, Blast_Score=181, Evalue=4e-47, Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=38.3064516129032, Blast_Score=134, Evalue=6e-33, Organism=Escherichia coli, GI87082100, Length=249, Percent_Identity=34.5381526104418, Blast_Score=124, Evalue=5e-30, Organism=Escherichia coli, GI1790717, Length=243, Percent_Identity=30.4526748971193, Blast_Score=123, Evalue=9e-30, Organism=Escherichia coli, GI1788459, Length=242, Percent_Identity=33.8842975206612, Blast_Score=116, Evalue=1e-27, Organism=Escherichia coli, GI1787905, Length=240, Percent_Identity=32.5, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI2367365, Length=242, Percent_Identity=34.7107438016529, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI87082160, Length=245, Percent_Identity=29.3877551020408, Blast_Score=94, Evalue=9e-21, Organism=Escherichia coli, GI1789057, Length=254, Percent_Identity=30.7086614173228, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI1786812, Length=192, Percent_Identity=33.8541666666667, Blast_Score=91, Evalue=6e-20, Organism=Escherichia coli, GI1789208, Length=246, Percent_Identity=28.0487804878049, Blast_Score=91, Evalue=8e-20, Organism=Escherichia coli, GI1789378, Length=248, Percent_Identity=31.0483870967742, Blast_Score=82, Evalue=4e-17, Organism=Escherichia coli, GI1787820, Length=223, Percent_Identity=30.4932735426009, Blast_Score=72, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17555706, Length=244, Percent_Identity=39.344262295082, Blast_Score=152, Evalue=1e-37, Organism=Caenorhabditis elegans, GI25147288, Length=241, Percent_Identity=37.344398340249, Blast_Score=132, Evalue=1e-31, Organism=Caenorhabditis elegans, GI17560676, Length=243, Percent_Identity=34.156378600823, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI115534694, Length=243, Percent_Identity=34.156378600823, Blast_Score=100, Evalue=9e-22, Organism=Caenorhabditis elegans, GI17536025, Length=247, Percent_Identity=31.5789473684211, Blast_Score=95, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17560150, Length=255, Percent_Identity=30.1960784313725, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17536651, Length=247, Percent_Identity=31.1740890688259, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17560332, Length=259, Percent_Identity=32.4324324324324, Blast_Score=94, Evalue=7e-20, Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=31.6, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17568967, Length=248, Percent_Identity=32.258064516129, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17531453, Length=259, Percent_Identity=32.046332046332, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17562990, Length=257, Percent_Identity=30.7392996108949, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17562908, Length=258, Percent_Identity=32.5581395348837, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17562906, Length=259, Percent_Identity=32.046332046332, Blast_Score=91, Evalue=6e-19, Organism=Caenorhabditis elegans, GI17561402, Length=259, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=6e-19, Organism=Caenorhabditis elegans, GI17559104, Length=257, Percent_Identity=31.5175097276265, Blast_Score=91, Evalue=7e-19, Organism=Caenorhabditis elegans, GI71994600, Length=254, Percent_Identity=31.496062992126, Blast_Score=87, Evalue=6e-18, Organism=Caenorhabditis elegans, GI17562904, Length=260, Percent_Identity=30, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17563726, Length=255, Percent_Identity=29.0196078431373, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17538486, Length=259, Percent_Identity=30.8880308880309, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=30.6818181818182, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17561272, Length=217, Percent_Identity=30.4147465437788, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17538480, Length=258, Percent_Identity=31.3953488372093, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17508651, Length=262, Percent_Identity=29.0076335877863, Blast_Score=84, Evalue=8e-17, Organism=Caenorhabditis elegans, GI17551412, Length=262, Percent_Identity=31.2977099236641, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI72000259, Length=255, Percent_Identity=30.1960784313725, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI17565030, Length=256, Percent_Identity=30.46875, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI193204405, Length=259, Percent_Identity=28.957528957529, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17560220, Length=257, Percent_Identity=29.5719844357977, Blast_Score=77, Evalue=6e-15, Organism=Caenorhabditis elegans, GI17508895, Length=192, Percent_Identity=27.6041666666667, Blast_Score=74, Evalue=7e-14, Organism=Caenorhabditis elegans, GI17544670, Length=257, Percent_Identity=27.2373540856031, Blast_Score=74, Evalue=9e-14, Organism=Caenorhabditis elegans, GI17538182, Length=252, Percent_Identity=28.1746031746032, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI193203115, Length=195, Percent_Identity=31.7948717948718, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI193203117, Length=238, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17564282, Length=238, Percent_Identity=26.890756302521, Blast_Score=65, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=244, Percent_Identity=31.5573770491803, Blast_Score=101, Evalue=9e-23, Organism=Saccharomyces cerevisiae, GI6324126, Length=247, Percent_Identity=26.3157894736842, Blast_Score=74, Evalue=2e-14, Organism=Saccharomyces cerevisiae, GI6323882, Length=195, Percent_Identity=31.2820512820513, Blast_Score=67, Evalue=3e-12, Organism=Drosophila melanogaster, GI24639444, Length=243, Percent_Identity=37.8600823045267, Blast_Score=133, Evalue=8e-32, Organism=Drosophila melanogaster, GI28571526, Length=246, Percent_Identity=36.5853658536585, Blast_Score=119, Evalue=2e-27, Organism=Drosophila melanogaster, GI21357041, Length=246, Percent_Identity=36.1788617886179, Blast_Score=118, Evalue=3e-27, Organism=Drosophila melanogaster, GI23397609, Length=244, Percent_Identity=35.655737704918, Blast_Score=112, Evalue=2e-25, Organism=Drosophila melanogaster, GI21355319, Length=245, Percent_Identity=32.6530612244898, Blast_Score=104, Evalue=6e-23, Organism=Drosophila melanogaster, GI24644339, Length=248, Percent_Identity=32.258064516129, Blast_Score=103, Evalue=1e-22, Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=30.7692307692308, Blast_Score=99, Evalue=3e-21, Organism=Drosophila melanogaster, GI18859837, Length=237, Percent_Identity=32.4894514767932, Blast_Score=89, Evalue=2e-18, Organism=Drosophila melanogaster, GI24644337, Length=167, Percent_Identity=35.3293413173653, Blast_Score=89, Evalue=3e-18, Organism=Drosophila melanogaster, GI17737361, Length=253, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI21355631, Length=214, Percent_Identity=28.9719626168224, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI116007236, Length=234, Percent_Identity=29.4871794871795, Blast_Score=65, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 24693; Mature: 24693
Theoretical pI: Translated: 7.56; Mature: 7.56
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.3 %Cys (Translated Protein) 2.5 %Met (Translated Protein) 3.8 %Cys+Met (Translated Protein) 1.3 %Cys (Mature Protein) 2.5 %Met (Mature Protein) 3.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKRALVTGGSGGIGAAICRRLAADSCHVYVHANRNLARASALADEIRAAGGAAEAVSFDV CCCEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEECH TDVAACRATLEALVESEPIQILVNNAGIHDDAVFPGMRAEQWHRVLDVSLNGFFNVTQPL HHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHEEECCCEEECCCCC TLPMIRSRWGRIVNITSVAGLTGNRGQANYAAAKGALHAATKSLSLELASRGVTVNAVAP HHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECC GVIRTAMSDGVFDDASIAALVPMKRAGQPEDVASAVAFLASDQASYISGQVLSVNGGMI HHHHHHHHCCCCCCCCHHEECCHHHCCCCHHHHHHHHHHHCCCHHHHCCEEEEECCCCC >Mature Secondary Structure MKRALVTGGSGGIGAAICRRLAADSCHVYVHANRNLARASALADEIRAAGGAAEAVSFDV CCCEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEECH TDVAACRATLEALVESEPIQILVNNAGIHDDAVFPGMRAEQWHRVLDVSLNGFFNVTQPL HHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHEEECCCEEECCCCC TLPMIRSRWGRIVNITSVAGLTGNRGQANYAAAKGALHAATKSLSLELASRGVTVNAVAP HHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECC GVIRTAMSDGVFDDASIAALVPMKRAGQPEDVASAVAFLASDQASYISGQVLSVNGGMI HHHHHHHHCCCCCCCCHHEECCHHHCCCCHHHHHHHHHHHCCCHHHHCCEEEEECCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8759840; 9384377; 9534248; 8654983 [H]