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The map label for this gene is 74318775

Identifier: 74318775

GI number: 74318775

Start: 2835943

End: 2837271

Strand: Direct

Name: 74318775

Synonym: Tbd_2757

Alternate gene names: NA

Gene position: 2835943-2837271 (Clockwise)

Preceding gene: 74318774

Following gene: 74318785

Centisome position: 97.46

GC content: 67.12

Gene sequence:

>1329_bases
GTGCATCAGAGCGAAGCGCTGCTGTTCTTCACCCTGCTTCAACTGACCGTAATCGTGCTCGCCGCGCGCGCCGGCGGCGC
GCTCGCACGGCGCGTCGGCCAATCGCCGGCGGTCGGCGAAATCATCGTCGGCATCCTGCTCGGACCCTCGCTGTTCGGCT
GGCTCGCGCCGGATCTCTTCCGCACCGTCTTTCAGGCGTCGTCGCCTGAGCCGATGCAGGTCGTGTCGCAGATCGGTCTG
GTGCTGCTGATGTTCCAGATCGGCCTCGAATTCGATTTCGCGCATCTCGCCGCGCGCAACAACCGGCGCGCCGTGCGCTA
CGTCGCGACGGCGAGCATGATCGCGCCCTTCGCGCTCGGCTTCGGTTTCGGCTACCTCAGCGCGCCGCTGCTGTCGCCGG
GCGCCGACGTCCTCGGCTCGGCGCTGTTCGTCGGCACGGCATTTTCGATCACGGCGCTGCCGATCCTTGGCCGCATCATG
ATCGAGCTCGAGATCACGCGGCACCCGCTCGCGGTGATCGCGATCAGCGCGGCGGCGATCAACGACGTCGTCGGCTGGCT
GCTGCTCGCCTTGGTCACCGCACTGACGCTCGCGCAGTTCAGCGCGGCGGGCTTCGCCCTCAAGCTGCTGCTCGTCGTCG
GCTTCTTCGCCTGCTGGTGGTTCGTCGTCCGCCCGCTCATGAAACGCGTGATCCACGCGAGCCAGCGGGCGTCGGCAACG
GTCAGCAAGGATAAAGGGCGCGACGGACTCAGCCACAATCTGCTGGGGGTCCTGTTCGCGGCGATCTTCCTGTCGGCGAT
CGCGACCTACCAGCTCGGCATTTTCGCGATCTTCGGCGGTTTCATGATGGGCGTCGTGCTCCACGACGAGCATGAACTCA
TCGCGGCGTGGCGCGAGCGCGTCGGCCATTTCGTGACGGTGTTCTTCCTGCCGGTGTTCTTCACCTACACCGGGCTGCGC
ACCGACATCGTCGGCCTCGATTCGGCCGAAGCCTGGGGCTGGTGCGCGCTGCTGATCGCGCTCGCCAGCCTCGGCAAGTT
CGGCGCGAGCTATCTCGCCGCGCGCTGGGCGGGCCTGTCGCGCGACGAGAGCAAGGTGATCGGCATCATGATGAACACGC
GGGCGCTGATGGAGCTCATCGTCATCAACGTCGGCTACGACCTCGGCGTGATTTCGCAGCAGCTCTTCACGATGCTCGTG
CTGATGGCGATCTTCAGCACCGTCATCACGATGCCCGGCCTGCGGCGCTGGTTGCCGCGCATTGGCGTCGGCCTGCCCGC
CGGCGCGTCGCCGCTGCCGCAGGCGGCCGCCCAGTCTTCGACGTCCTGA

Upstream 100 bases:

>100_bases
CCGTCGCATTCCTCGCCTCGGACCAGGCGAGCTACATCAGCGGGCAGGTGCTGTCGGTCAACGGAGGCATGATCTGAACG
ACGCCACCCGCGCGCTCGCC

Downstream 100 bases:

>100_bases
GCGCCGGCGGCCGGTTCAACCCGGCTTCACCGCCTGATATTCGGCGAGTATGGAAAGCGCGCGCGTCTCGACGTGCCGGC
GCACGGCGAGGAAACCCGCG

Product: sodium/hydrogen exchanger family protein

Products: NA

Alternate protein names: MjNapA [H]

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MHQSEALLFFTLLQLTVIVLAARAGGALARRVGQSPAVGEIIVGILLGPSLFGWLAPDLFRTVFQASSPEPMQVVSQIGL
VLLMFQIGLEFDFAHLAARNNRRAVRYVATASMIAPFALGFGFGYLSAPLLSPGADVLGSALFVGTAFSITALPILGRIM
IELEITRHPLAVIAISAAAINDVVGWLLLALVTALTLAQFSAAGFALKLLLVVGFFACWWFVVRPLMKRVIHASQRASAT
VSKDKGRDGLSHNLLGVLFAAIFLSAIATYQLGIFAIFGGFMMGVVLHDEHELIAAWRERVGHFVTVFFLPVFFTYTGLR
TDIVGLDSAEAWGWCALLIALASLGKFGASYLAARWAGLSRDESKVIGIMMNTRALMELIVINVGYDLGVISQQLFTMLV
LMAIFSTVITMPGLRRWLPRIGVGLPAGASPLPQAAAQSSTS

Sequences:

>Translated_442_residues
MHQSEALLFFTLLQLTVIVLAARAGGALARRVGQSPAVGEIIVGILLGPSLFGWLAPDLFRTVFQASSPEPMQVVSQIGL
VLLMFQIGLEFDFAHLAARNNRRAVRYVATASMIAPFALGFGFGYLSAPLLSPGADVLGSALFVGTAFSITALPILGRIM
IELEITRHPLAVIAISAAAINDVVGWLLLALVTALTLAQFSAAGFALKLLLVVGFFACWWFVVRPLMKRVIHASQRASAT
VSKDKGRDGLSHNLLGVLFAAIFLSAIATYQLGIFAIFGGFMMGVVLHDEHELIAAWRERVGHFVTVFFLPVFFTYTGLR
TDIVGLDSAEAWGWCALLIALASLGKFGASYLAARWAGLSRDESKVIGIMMNTRALMELIVINVGYDLGVISQQLFTMLV
LMAIFSTVITMPGLRRWLPRIGVGLPAGASPLPQAAAQSSTS
>Mature_442_residues
MHQSEALLFFTLLQLTVIVLAARAGGALARRVGQSPAVGEIIVGILLGPSLFGWLAPDLFRTVFQASSPEPMQVVSQIGL
VLLMFQIGLEFDFAHLAARNNRRAVRYVATASMIAPFALGFGFGYLSAPLLSPGADVLGSALFVGTAFSITALPILGRIM
IELEITRHPLAVIAISAAAINDVVGWLLLALVTALTLAQFSAAGFALKLLLVVGFFACWWFVVRPLMKRVIHASQRASAT
VSKDKGRDGLSHNLLGVLFAAIFLSAIATYQLGIFAIFGGFMMGVVLHDEHELIAAWRERVGHFVTVFFLPVFFTYTGLR
TDIVGLDSAEAWGWCALLIALASLGKFGASYLAARWAGLSRDESKVIGIMMNTRALMELIVINVGYDLGVISQQLFTMLV
LMAIFSTVITMPGLRRWLPRIGVGLPAGASPLPQAAAQSSTS

Specific function: This is probably a Na(+)/H(+) antiporter [H]

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6322367, Length=424, Percent_Identity=29.2452830188679, Blast_Score=181, Evalue=3e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 47407; Mature: 47407

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHQSEALLFFTLLQLTVIVLAARAGGALARRVGQSPAVGEIIVGILLGPSLFGWLAPDLF
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RTVFQASSPEPMQVVSQIGLVLLMFQIGLEFDFAHLAARNNRRAVRYVATASMIAPFALG
HHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
FGFGYLSAPLLSPGADVLGSALFVGTAFSITALPILGRIMIELEITRHPLAVIAISAAAI
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHH
NDVVGWLLLALVTALTLAQFSAAGFALKLLLVVGFFACWWFVVRPLMKRVIHASQRASAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VSKDKGRDGLSHNLLGVLFAAIFLSAIATYQLGIFAIFGGFMMGVVLHDEHELIAAWRER
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
VGHFVTVFFLPVFFTYTGLRTDIVGLDSAEAWGWCALLIALASLGKFGASYLAARWAGLS
HHHHHHHHHHHHHHHHHCCHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RDESKVIGIMMNTRALMELIVINVGYDLGVISQQLFTMLVLMAIFSTVITMPGLRRWLPR
CCCCCEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
IGVGLPAGASPLPQAAAQSSTS
HCCCCCCCCCCCCHHHHCCCCC
>Mature Secondary Structure
MHQSEALLFFTLLQLTVIVLAARAGGALARRVGQSPAVGEIIVGILLGPSLFGWLAPDLF
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RTVFQASSPEPMQVVSQIGLVLLMFQIGLEFDFAHLAARNNRRAVRYVATASMIAPFALG
HHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
FGFGYLSAPLLSPGADVLGSALFVGTAFSITALPILGRIMIELEITRHPLAVIAISAAAI
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHH
NDVVGWLLLALVTALTLAQFSAAGFALKLLLVVGFFACWWFVVRPLMKRVIHASQRASAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VSKDKGRDGLSHNLLGVLFAAIFLSAIATYQLGIFAIFGGFMMGVVLHDEHELIAAWRER
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
VGHFVTVFFLPVFFTYTGLRTDIVGLDSAEAWGWCALLIALASLGKFGASYLAARWAGLS
HHHHHHHHHHHHHHHHHCCHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RDESKVIGIMMNTRALMELIVINVGYDLGVISQQLFTMLVLMAIFSTVITMPGLRRWLPR
CCCCCEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
IGVGLPAGASPLPQAAAQSSTS
HCCCCCCCCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]