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The map label for this gene is purC [H]

Identifier: 74318686

GI number: 74318686

Start: 2740951

End: 2742948

Strand: Direct

Name: purC [H]

Synonym: Tbd_2668

Alternate gene names: 74318686

Gene position: 2740951-2742948 (Clockwise)

Preceding gene: 74318681

Following gene: 74318688

Centisome position: 94.2

GC content: 68.47

Gene sequence:

>1998_bases
ATGAATACGATCCGCCCGCTCAACATTCCCTGGCTGGCCCTCGGCGCAACGCTGCTCGTCGCCGGCCTGCTGATCTATCT
GCTCGGGCCGATTCTGACGCCTTTCCTCGCGGGCGCCCTGCTCGCCTACATCTTCGACCCGCTCGTCGACCGGCTCGAGG
CACGCCGCATCCCGCGCGCCGCCGGCACGGCCATCGTCATCGTGCTCGCGGGACTCATCCTGTTCGGCCTCCTGCTCGTC
GCGCTGCCGCTCTTCCAGGGGCAGTTCGCCGAATTGAGCCAGCGCGTCCCCGCAGGGCTGGACCTGCTGCAGACGCGCTT
CCTGCCCTGGGTCGAGCGGACTTTCGGGATCGCGGTCAGCCCCCATCTCGACGGACTCAAGGCCTGGCTCACCGAGAAGG
CGACGCAGCAGGGGGCGAACTGGCTGCCGCGGCTGCAGACCGGCGCGCTCGCGATCATCGGCGCGCTGGTCAACCTGCTG
CTCATTCCCGTCGTCATGTTTTATCTGCTGAAGGACTGGGACGTCATCGTCGGACGCGTCGCCGCGCTCGCGCCGCGTCC
CTGGCTGCCGGCGGCGCGGCGCATCGGCAGCGCGATGAACGCGGTGGTCGGAGAATTCCTGCGCGGCCAGCTCGCGGTCA
TGATCACGCTCTCGGTCTATTACAGCGTGGCGCTGTGGGCGGTCGGGCTCGATTACGCGCTGCCGATCGGCGTTCTGACC
GGCGTGCTGTCCTTCGTGCCCTTCCTCGGCTTCGGCCTCGGCATGGTCCTCGCGCTGCTGGTCGCGCTGCTGCAGTACCC
GGACTGGGTCGGCGTCGCCTGGGTCGCCGGGGTCTATCTCGCCGGGCAGGCGCTCGAAAGCTACGTCGTCACCCCGCGCC
TGGTCGGCGAGCGCGTCGGCCTGCATCCGGTCGCGGTGATCTTTGCGCTCGCAGCCTTCGGCCAGTTGTTCGGCTTCGTC
GGCGTCCTGCTCGCGGTGCCGCTCGCCGCGACCCTGCTCGTCGGATTGCGCGAATTGCGCGCCGTCTACCAGGCCAGTAG
CTTCTACCGCGGCGGCTATAATCCCGGCTTTTCCGGTTCCGCCATGCCCGCCATGTCCGCCCCCCTCTCCGGCCAGCCCC
TGTTCGAATCGCATATCGCCTCGCTGCCGCTCATCCACCGCGGCAAGGTGCGCGACATCTACGCGGTGGGCGACGACAAG
CTGCTGATCGTCACGACCGACCGCCTGTCGGCGTTCGACGTCGTCATGCCGACGCCGATCCCGGGCAAGGGTGAGGTGCT
GACGCGGGTCTCGGCGTTCTGGTTCGACAAGCTGCGGGCCGTCGTTCCGAACCAGACGCTCGCGATTGCGCCGGAAGCCG
TGGTCGCGGAAGACGAAAAAGACCAGGTCGCGGGGCGCGCGATCGTGGTGCAAAAGCTCAAGGCGCTGCCGATCGAGGCG
ATCGTGCGCGGCTACCTCGTGGGTTCAGGATGGAAGGAATACCAGCGGAGCCAGTCGGTCTGCGGCATCGCGCTGCCCGC
CGGCCTCATGCAGGCCGACCGCCTGCCCGAGCCGATCTTCACGCCGTCGACCAAGGCGGCGCTCGGCGCGCACGACGAAA
ACATCGCGTTCGAACAGATGGCCGAGCGCATCGGCGCCGAGCTCGCCGCCCAGGTGCGCGACGTCAGCCTTGCGCTCTAC
CAGGCGGCCGCCGAGTACGCGCGCACGCGCGGCATCATCATCGCCGACACCAAATTCGAATTCGGCCTCGACGCGGCAGG
CCAGCTGATGTGGATCGACGAGGCACTGACCCCGGATTCGTCGCGCTTCTGGCCCGCCGACCAGTACCGTCCGGGCAGCA
ATCCCCCGAGCTTCGACAAACAGTTCGTGCGCGACTGGCTCGAAGCGAGCGGATGGAACAAGCAAGCCCCGGGGCCGGCG
CTGCCGGCCGACATCGTCGCGCGGACGAGCGAGAAATACCGCGAGGCGATGGTCCGCCTGCTCGGCGACGCTATTTGA

Upstream 100 bases:

>100_bases
ACCAGCGCGTCGCCCGCGTCGATGTCGACGCCGGCATCTTTGTAGGAAATGGATGACAACGTGGGCTCCAGCTGCAAAAA
AGTGCGTTATTTTACCGCCT

Downstream 100 bases:

>100_bases
GCGTCGCGTCGAGGAATTCGGCGACCGCCGCGACCATCGCCGCTTCGTGGCCGCTGAAGAAATGGTCGCTGCGCGGCACG
ACGACCTGCCGCGACGCCTT

Product: phosphoribosylaminoimidazole-succinocarboxamide synthase

Products: NA

Alternate protein names: SAICAR synthetase [H]

Number of amino acids: Translated: 665; Mature: 665

Protein sequence:

>665_residues
MNTIRPLNIPWLALGATLLVAGLLIYLLGPILTPFLAGALLAYIFDPLVDRLEARRIPRAAGTAIVIVLAGLILFGLLLV
ALPLFQGQFAELSQRVPAGLDLLQTRFLPWVERTFGIAVSPHLDGLKAWLTEKATQQGANWLPRLQTGALAIIGALVNLL
LIPVVMFYLLKDWDVIVGRVAALAPRPWLPAARRIGSAMNAVVGEFLRGQLAVMITLSVYYSVALWAVGLDYALPIGVLT
GVLSFVPFLGFGLGMVLALLVALLQYPDWVGVAWVAGVYLAGQALESYVVTPRLVGERVGLHPVAVIFALAAFGQLFGFV
GVLLAVPLAATLLVGLRELRAVYQASSFYRGGYNPGFSGSAMPAMSAPLSGQPLFESHIASLPLIHRGKVRDIYAVGDDK
LLIVTTDRLSAFDVVMPTPIPGKGEVLTRVSAFWFDKLRAVVPNQTLAIAPEAVVAEDEKDQVAGRAIVVQKLKALPIEA
IVRGYLVGSGWKEYQRSQSVCGIALPAGLMQADRLPEPIFTPSTKAALGAHDENIAFEQMAERIGAELAAQVRDVSLALY
QAAAEYARTRGIIIADTKFEFGLDAAGQLMWIDEALTPDSSRFWPADQYRPGSNPPSFDKQFVRDWLEASGWNKQAPGPA
LPADIVARTSEKYREAMVRLLGDAI

Sequences:

>Translated_665_residues
MNTIRPLNIPWLALGATLLVAGLLIYLLGPILTPFLAGALLAYIFDPLVDRLEARRIPRAAGTAIVIVLAGLILFGLLLV
ALPLFQGQFAELSQRVPAGLDLLQTRFLPWVERTFGIAVSPHLDGLKAWLTEKATQQGANWLPRLQTGALAIIGALVNLL
LIPVVMFYLLKDWDVIVGRVAALAPRPWLPAARRIGSAMNAVVGEFLRGQLAVMITLSVYYSVALWAVGLDYALPIGVLT
GVLSFVPFLGFGLGMVLALLVALLQYPDWVGVAWVAGVYLAGQALESYVVTPRLVGERVGLHPVAVIFALAAFGQLFGFV
GVLLAVPLAATLLVGLRELRAVYQASSFYRGGYNPGFSGSAMPAMSAPLSGQPLFESHIASLPLIHRGKVRDIYAVGDDK
LLIVTTDRLSAFDVVMPTPIPGKGEVLTRVSAFWFDKLRAVVPNQTLAIAPEAVVAEDEKDQVAGRAIVVQKLKALPIEA
IVRGYLVGSGWKEYQRSQSVCGIALPAGLMQADRLPEPIFTPSTKAALGAHDENIAFEQMAERIGAELAAQVRDVSLALY
QAAAEYARTRGIIIADTKFEFGLDAAGQLMWIDEALTPDSSRFWPADQYRPGSNPPSFDKQFVRDWLEASGWNKQAPGPA
LPADIVARTSEKYREAMVRLLGDAI
>Mature_665_residues
MNTIRPLNIPWLALGATLLVAGLLIYLLGPILTPFLAGALLAYIFDPLVDRLEARRIPRAAGTAIVIVLAGLILFGLLLV
ALPLFQGQFAELSQRVPAGLDLLQTRFLPWVERTFGIAVSPHLDGLKAWLTEKATQQGANWLPRLQTGALAIIGALVNLL
LIPVVMFYLLKDWDVIVGRVAALAPRPWLPAARRIGSAMNAVVGEFLRGQLAVMITLSVYYSVALWAVGLDYALPIGVLT
GVLSFVPFLGFGLGMVLALLVALLQYPDWVGVAWVAGVYLAGQALESYVVTPRLVGERVGLHPVAVIFALAAFGQLFGFV
GVLLAVPLAATLLVGLRELRAVYQASSFYRGGYNPGFSGSAMPAMSAPLSGQPLFESHIASLPLIHRGKVRDIYAVGDDK
LLIVTTDRLSAFDVVMPTPIPGKGEVLTRVSAFWFDKLRAVVPNQTLAIAPEAVVAEDEKDQVAGRAIVVQKLKALPIEA
IVRGYLVGSGWKEYQRSQSVCGIALPAGLMQADRLPEPIFTPSTKAALGAHDENIAFEQMAERIGAELAAQVRDVSLALY
QAAAEYARTRGIIIADTKFEFGLDAAGQLMWIDEALTPDSSRFWPADQYRPGSNPPSFDKQFVRDWLEASGWNKQAPGPA
LPADIVARTSEKYREAMVRLLGDAI

Specific function: Unknown

COG id: COG0152

COG function: function code F; Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SAICAR synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1788838, Length=317, Percent_Identity=27.7602523659306, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6319326, Length=291, Percent_Identity=48.1099656357388, Blast_Score=273, Evalue=6e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013816
- InterPro:   IPR001636
- InterPro:   IPR018236 [H]

Pfam domain/function: PF01259 SAICAR_synt [H]

EC number: =6.3.2.6 [H]

Molecular weight: Translated: 71749; Mature: 71749

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: PS01058 SAICAR_SYNTHETASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTIRPLNIPWLALGATLLVAGLLIYLLGPILTPFLAGALLAYIFDPLVDRLEARRIPRA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
AGTAIVIVLAGLILFGLLLVALPLFQGQFAELSQRVPAGLDLLQTRFLPWVERTFGIAVS
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCEEC
PHLDGLKAWLTEKATQQGANWLPRLQTGALAIIGALVNLLLIPVVMFYLLKDWDVIVGRV
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AALAPRPWLPAARRIGSAMNAVVGEFLRGQLAVMITLSVYYSVALWAVGLDYALPIGVLT
HHHCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVLSFVPFLGFGLGMVLALLVALLQYPDWVGVAWVAGVYLAGQALESYVVTPRLVGERVG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCC
LHPVAVIFALAAFGQLFGFVGVLLAVPLAATLLVGLRELRAVYQASSFYRGGYNPGFSGS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
AMPAMSAPLSGQPLFESHIASLPLIHRGKVRDIYAVGDDKLLIVTTDRLSAFDVVMPTPI
CCCCCCCCCCCCCHHHHHHHHCCCEECCCCCEEEEECCCEEEEEECCCCCEECEEECCCC
PGKGEVLTRVSAFWFDKLRAVVPNQTLAIAPEAVVAEDEKDQVAGRAIVVQKLKALPIEA
CCCCHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHCCCCHHHHHHHHHHHHHHHHCCHHH
IVRGYLVGSGWKEYQRSQSVCGIALPAGLMQADRLPEPIFTPSTKAALGAHDENIAFEQM
HHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCHHHHHH
AERIGAELAAQVRDVSLALYQAAAEYARTRGIIIADTKFEFGLDAAGQLMWIDEALTPDS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCEEEEECCCCCCC
SRFWPADQYRPGSNPPSFDKQFVRDWLEASGWNKQAPGPALPADIVARTSEKYREAMVRL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LGDAI
HHCCC
>Mature Secondary Structure
MNTIRPLNIPWLALGATLLVAGLLIYLLGPILTPFLAGALLAYIFDPLVDRLEARRIPRA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
AGTAIVIVLAGLILFGLLLVALPLFQGQFAELSQRVPAGLDLLQTRFLPWVERTFGIAVS
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCEEC
PHLDGLKAWLTEKATQQGANWLPRLQTGALAIIGALVNLLLIPVVMFYLLKDWDVIVGRV
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AALAPRPWLPAARRIGSAMNAVVGEFLRGQLAVMITLSVYYSVALWAVGLDYALPIGVLT
HHHCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVLSFVPFLGFGLGMVLALLVALLQYPDWVGVAWVAGVYLAGQALESYVVTPRLVGERVG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCC
LHPVAVIFALAAFGQLFGFVGVLLAVPLAATLLVGLRELRAVYQASSFYRGGYNPGFSGS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
AMPAMSAPLSGQPLFESHIASLPLIHRGKVRDIYAVGDDKLLIVTTDRLSAFDVVMPTPI
CCCCCCCCCCCCCHHHHHHHHCCCEECCCCCEEEEECCCEEEEEECCCCCEECEEECCCC
PGKGEVLTRVSAFWFDKLRAVVPNQTLAIAPEAVVAEDEKDQVAGRAIVVQKLKALPIEA
CCCCHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHCCCCHHHHHHHHHHHHHHHHCCHHH
IVRGYLVGSGWKEYQRSQSVCGIALPAGLMQADRLPEPIFTPSTKAALGAHDENIAFEQM
HHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCHHHHHH
AERIGAELAAQVRDVSLALYQAAAEYARTRGIIIADTKFEFGLDAAGQLMWIDEALTPDS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCEEEEECCCCCCC
SRFWPADQYRPGSNPPSFDKQFVRDWLEASGWNKQAPGPALPADIVARTSEKYREAMVRL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LGDAI
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA