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The map label for this gene is cbbF

Identifier: 74318595

GI number: 74318595

Start: 2652028

End: 2653041

Strand: Direct

Name: cbbF

Synonym: Tbd_2577

Alternate gene names: 74318595

Gene position: 2652028-2653041 (Clockwise)

Preceding gene: 74318594

Following gene: 74318597

Centisome position: 91.14

GC content: 64.0

Gene sequence:

>1014_bases
ATGCACACCGGCACCACCCTTACCCAGTTCATCATTGAAGAGCAACGTCGCACCGCGGGTGCGACCGGCGACTTCACCTC
GCTGCTTAACGACGTCGTCACCGCGTGCAAGGCGATTTCGAACGCCGTCAACAAGGGCGCGCTGCTGGGCGTGATGGGCG
CACTCGAATCCGAGAACGTGCAGGGCGAGACGCAGAAGAAACTCGACGTGATCACCAACGACATCATGATCCGCTCGAAC
GAGTGGGCCGGCCACCTGGCCGGCATGGCGTCCGAGGAAATGGACGACGTCTACGCCATCCCCGGCCAGTACCCGCTCGG
CAAGTATCTGCTGGTGTTCGACCCGCTCGACGGATCAAGCAACGTCGACGTCAACATCTCGGTCGGCACGATCTTCTCGA
TCCTCAAGGCTCCGGTCGCCGGCCGCGCCGCGAAGGCTGAGGACTTCCTGCAGGCCGGCACCAAGCAGGTCTGCGCCGGC
TACGCGATCTACGGTTCGTCGACCATGCTGGTCCTGACCTTCGGCCACGGCACCAACGGCTTCACGCTCGACCGCGACGT
CGGCGAGTTCGTGCTGACCCATCCCGCCATGAAAATCCCGACCGAAACCAAGGAATTCGCGATCAACGCGTCGAACATGC
GTTTCTGGGAAAAGCCCGTGCAGCGCTACGTCGACGAATGCCTCGCCGGCAAGACCGGTCCGCGCGGCAAGGACTTCAAC
ATGCGCTGGGTCGCGTCGATGGTCGCCGAAGTGCACCGCATCCTGACCCGCGGCGGCATCTTCATGTACCCCAAGGACAC
CAAGGACCCGTCCAAGGCCGGCAAGCTGCGCCTGATGTACGAAGCGAATCCGATGGCGTTCATCGTCGAGCAGGCCGGCG
GCGCGGCGACGACCGGCTACCAGCGCATCCTCGACATCGCCCCGGAAGGCCTGCACCAGCGCGTGCCGGTGATCCTCGGC
TCGAAGACCGAAGTCGACACGGTGACGGGCTACCACCACGAAAAGGCGGCGTAA

Upstream 100 bases:

>100_bases
CTCAAGCTTTCCCCGCCTGCCGGCCGCGGATTCACGCGCTTTATCACGTGATAAAATCTTTGATTGTTCGAATATTTTTC
TCTACTTCTGGAGTTCCGTC

Downstream 100 bases:

>100_bases
GGCGGCCGCCGAAGCCGAGCAAAAGCCGGGCTGTGCGCCCGGCTTTTTTTTGCGTCAGGCCGCTACCACGCCGGCGCGCA
TCAGGCGCGTGCAGGCATCG

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MHTGTTLTQFIIEEQRRTAGATGDFTSLLNDVVTACKAISNAVNKGALLGVMGALESENVQGETQKKLDVITNDIMIRSN
EWAGHLAGMASEEMDDVYAIPGQYPLGKYLLVFDPLDGSSNVDVNISVGTIFSILKAPVAGRAAKAEDFLQAGTKQVCAG
YAIYGSSTMLVLTFGHGTNGFTLDRDVGEFVLTHPAMKIPTETKEFAINASNMRFWEKPVQRYVDECLAGKTGPRGKDFN
MRWVASMVAEVHRILTRGGIFMYPKDTKDPSKAGKLRLMYEANPMAFIVEQAGGAATTGYQRILDIAPEGLHQRVPVILG
SKTEVDTVTGYHHEKAA

Sequences:

>Translated_337_residues
MHTGTTLTQFIIEEQRRTAGATGDFTSLLNDVVTACKAISNAVNKGALLGVMGALESENVQGETQKKLDVITNDIMIRSN
EWAGHLAGMASEEMDDVYAIPGQYPLGKYLLVFDPLDGSSNVDVNISVGTIFSILKAPVAGRAAKAEDFLQAGTKQVCAG
YAIYGSSTMLVLTFGHGTNGFTLDRDVGEFVLTHPAMKIPTETKEFAINASNMRFWEKPVQRYVDECLAGKTGPRGKDFN
MRWVASMVAEVHRILTRGGIFMYPKDTKDPSKAGKLRLMYEANPMAFIVEQAGGAATTGYQRILDIAPEGLHQRVPVILG
SKTEVDTVTGYHHEKAA
>Mature_337_residues
MHTGTTLTQFIIEEQRRTAGATGDFTSLLNDVVTACKAISNAVNKGALLGVMGALESENVQGETQKKLDVITNDIMIRSN
EWAGHLAGMASEEMDDVYAIPGQYPLGKYLLVFDPLDGSSNVDVNISVGTIFSILKAPVAGRAAKAEDFLQAGTKQVCAG
YAIYGSSTMLVLTFGHGTNGFTLDRDVGEFVLTHPAMKIPTETKEFAINASNMRFWEKPVQRYVDECLAGKTGPRGKDFN
MRWVASMVAEVHRILTRGGIFMYPKDTKDPSKAGKLRLMYEANPMAFIVEQAGGAATTGYQRILDIAPEGLHQRVPVILG
SKTEVDTVTGYHHEKAA

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family

Homologues:

Organism=Homo sapiens, GI22907028, Length=320, Percent_Identity=44.375, Blast_Score=254, Evalue=1e-67,
Organism=Homo sapiens, GI189083692, Length=324, Percent_Identity=45.3703703703704, Blast_Score=251, Evalue=5e-67,
Organism=Homo sapiens, GI16579888, Length=324, Percent_Identity=45.3703703703704, Blast_Score=251, Evalue=5e-67,
Organism=Escherichia coli, GI1790679, Length=331, Percent_Identity=44.4108761329305, Blast_Score=274, Evalue=5e-75,
Organism=Caenorhabditis elegans, GI17508131, Length=326, Percent_Identity=46.319018404908, Blast_Score=290, Evalue=9e-79,
Organism=Saccharomyces cerevisiae, GI6323409, Length=322, Percent_Identity=42.5465838509317, Blast_Score=267, Evalue=2e-72,
Organism=Drosophila melanogaster, GI45550998, Length=327, Percent_Identity=45.8715596330275, Blast_Score=269, Evalue=2e-72,
Organism=Drosophila melanogaster, GI19921562, Length=327, Percent_Identity=45.8715596330275, Blast_Score=269, Evalue=2e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): F16PA_THIDA (Q3SFS6)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_316335.1
- HSSP:   P00636
- ProteinModelPortal:   Q3SFS6
- SMR:   Q3SFS6
- STRING:   Q3SFS6
- GeneID:   3672553
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_2577
- NMPDR:   fig|292415.3.peg.2650
- eggNOG:   COG0158
- HOGENOM:   HBG731261
- OMA:   YSINEGS
- PhylomeDB:   Q3SFS6
- ProtClustDB:   PRK09293
- BioCyc:   TDEN292415:TBD_2577-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01855
- InterPro:   IPR000146
- PANTHER:   PTHR11556
- PRINTS:   PR00115

Pfam domain/function: PF00316 FBPase

EC number: =3.1.3.11

Molecular weight: Translated: 36557; Mature: 36557

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00124 FBPASE

Important sites: BINDING 209-209 BINDING 275-275

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTGTTLTQFIIEEQRRTAGATGDFTSLLNDVVTACKAISNAVNKGALLGVMGALESENV
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
QGETQKKLDVITNDIMIRSNEWAGHLAGMASEEMDDVYAIPGQYPLGKYLLVFDPLDGSS
CCHHHHHHHHHHCCEEEECCCCCHHHHCCCHHHCCCEEECCCCCCCCCEEEEEECCCCCC
NVDVNISVGTIFSILKAPVAGRAAKAEDFLQAGTKQVCAGYAIYGSSTMLVLTFGHGTNG
CEEEEEEHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHCCEEEECCCEEEEEEECCCCCC
FTLDRDVGEFVLTHPAMKIPTETKEFAINASNMRFWEKPVQRYVDECLAGKTGPRGKDFN
EEECCCHHHHHHHCCCCCCCCCCHHHEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
MRWVASMVAEVHRILTRGGIFMYPKDTKDPSKAGKLRLMYEANPMAFIVEQAGGAATTGY
HHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCEEEEEECCCEEEEEECCCCCCHHHH
QRILDIAPEGLHQRVPVILGSKTEVDTVTGYHHEKAA
HHHHHHCCCCHHCCCCEEECCCCCCCHHCCCCCCCCC
>Mature Secondary Structure
MHTGTTLTQFIIEEQRRTAGATGDFTSLLNDVVTACKAISNAVNKGALLGVMGALESENV
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
QGETQKKLDVITNDIMIRSNEWAGHLAGMASEEMDDVYAIPGQYPLGKYLLVFDPLDGSS
CCHHHHHHHHHHCCEEEECCCCCHHHHCCCHHHCCCEEECCCCCCCCCEEEEEECCCCCC
NVDVNISVGTIFSILKAPVAGRAAKAEDFLQAGTKQVCAGYAIYGSSTMLVLTFGHGTNG
CEEEEEEHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHCCEEEECCCEEEEEEECCCCCC
FTLDRDVGEFVLTHPAMKIPTETKEFAINASNMRFWEKPVQRYVDECLAGKTGPRGKDFN
EEECCCHHHHHHHCCCCCCCCCCHHHEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
MRWVASMVAEVHRILTRGGIFMYPKDTKDPSKAGKLRLMYEANPMAFIVEQAGGAATTGY
HHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCEEEEEECCCEEEEEECCCCCCHHHH
QRILDIAPEGLHQRVPVILGSKTEVDTVTGYHHEKAA
HHHHHHCCCCHHCCCCEEECCCCCCCHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA