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The map label for this gene is rnr [C]

Identifier: 74318593

GI number: 74318593

Start: 2649152

End: 2651011

Strand: Direct

Name: rnr [C]

Synonym: Tbd_2575

Alternate gene names: 74318593

Gene position: 2649152-2651011 (Clockwise)

Preceding gene: 74318592

Following gene: 74318594

Centisome position: 91.04

GC content: 65.97

Gene sequence:

>1860_bases
ATGCACGTCATTTTCGAAGAAGACGGCCATTTCAAGGCCGGCTCCATCCTGTCCGAAACCGAGGCGACCGCGCAGGTCGA
GTCGGCTTCGGGCAAGCGCAGCAAGGTCAAGGCCGCGGCGATCCTGCTGCGTTTTACCGCGCCGGCGCCGGAGGACGTGA
TGAGCGCCGCGGAAAAGCTCGGCGAGGAACTCGACGCCGACTTCCTGTGGGAAGCGGCCGGGAGCGAGGAGTTCGGCTTC
GAGCAACTGGCCGGGGAGTACTACGGACACGCGCCCAGCCCGGCGGAATCGGTCGCGCTATTGCAGAAGCTGCACGCCTC
GCCGATCTATTTCCACAAGAAGGGCAAGGGTCGCTACCGTCCGGCGCCACCGGAGACGCTCGCCGCGGCCAAGGCCGGCC
TCGAGAAGAAGCGTATCGCGGCCGAACGCCAAGCCTATCTCGCCCATGAACTCGCGGCCTTCCGCCTGCCACCCGAATAC
GCGTCGCTGATTCCGCGCATCCTGATCGCGCCGGACAAGAACACGCTCGAATACAAGGCGCTCGAGGACGCCGCCGCCGC
GACCGGACTGTCGCCGCTAAGGCTCGTCGAGCGGTGCGGCGCGATCCCTTCGACGCTCGATTTCCATTTGATGAGCTTCC
TGCTCGAATATTTTCCGCGTGGCACGGGCTTTGCGCCCGTGACGGAGCCGCTCGACCCGCCCGAGTTGCCGTCGAGCCCC
GTGCGAGCATTCTCGATGGACGACGAGGCGACGACCGAGATCGACGACGCCTTGAGCGTCGCGTGGCACGACGACGGCAG
CGTGCGCGTGGGCATCCACATCGCGGCGCCAGCGCTCGGCATCGCCCCCGGTTCCGAACTCGACCGCGTCGCGCGCGAGC
GTTTGTCGACCGTGTATTTTCCGGGCGACAAGATCACGATGCTGCCCGAGACCCTGATCCATCACTACACGCTCGGCGAA
GCGCACGACTGCCCGGCGCTGTCGCTATACGTCGACGTCGCCGCCGACCTGCGCGTGCTCGGCACCGAAACGCGACTCGA
GATGGTGCACATCGCCGACAACCTGCGCCACGAAACGCTGGAAATCGAATTCAACGCGGAGACCCTGCGCAACCCGGCGG
TCGCGGACTACCCCTATCGCCGCGAACTCGAATGGCTGCACGACTTCGCCGCCGTTCTCGAAGCCGGCCGCGGCAAGACC
GACACGGTCGAGCGCGTCGACTACAGTTTCAAGCTCGACGGCGACCGCATCAGCATCGCGCCGCGCAAACGCGGCAGCCC
GATCGACAAGGTCGTTTCCGAACTCATGATCTTTGCCAACGCGCACTGGGGTGGCTGGCTCGCGGAAAAACGCGTTCCCG
GCATCTATCGCGCACAGGCCAACGGCAAGACGCGGATGACGACCGCGCCCGACCCGCACGTCGGCCTCGGCGTCGACCAG
TACGCGTGGTCGACGTCGCCGTTGCGGCGCTATGTCGATCTCGTCAATCAGCGCCAACTCATCAGCCTTGTCCGCGACGA
GGACCCGGTTTACCCGCCGCGCAGCGAGGCGCTGTTTTCAGTGGTGCGCGAATTCGAGCTCGCCTACGACGCCTACAACG
ATTTCCAGCGCCGCCTCGAGCGCTACTGGATGTTGCGCTGGCTGATCCAGGAAAACGTCGACGAAATCGTCGCCAGCGTG
ATCCGCGAGGATCTCGTGCGCTTCGACGCCCTGCCGATGGTGACCCGCGCGCCCTCGGTCGCGGGGCTCGCGCCCGGAAC
CCGCGTCCGCCTGGCGATCTCCAACATCGACCTGCTCGACATCAGCTTCCACGCCGAATATCTCGAGACCGTGCCTGACA
GCACGGCCGCCGTTCCGTAG

Upstream 100 bases:

>100_bases
CCGTCGCCTACTACGCCGGCGCCCGCCAGATCGTCGAGACGGGCGGCGATCACGGCTTCGTCGGATTCGAGCGCCACTTC
CAAACGATTCTGGATTTCTG

Downstream 100 bases:

>100_bases
AATCGACGAACCCACTTTCGCGCACCATGGCGTCCATTCAACCCGTCTCTCTTGCCGAACCGTCCAAACAGGGAACGCGC
ATGGCGCTGGCCCTGCTCGC

Product: ribonuclease II

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 619; Mature: 619

Protein sequence:

>619_residues
MHVIFEEDGHFKAGSILSETEATAQVESASGKRSKVKAAAILLRFTAPAPEDVMSAAEKLGEELDADFLWEAAGSEEFGF
EQLAGEYYGHAPSPAESVALLQKLHASPIYFHKKGKGRYRPAPPETLAAAKAGLEKKRIAAERQAYLAHELAAFRLPPEY
ASLIPRILIAPDKNTLEYKALEDAAAATGLSPLRLVERCGAIPSTLDFHLMSFLLEYFPRGTGFAPVTEPLDPPELPSSP
VRAFSMDDEATTEIDDALSVAWHDDGSVRVGIHIAAPALGIAPGSELDRVARERLSTVYFPGDKITMLPETLIHHYTLGE
AHDCPALSLYVDVAADLRVLGTETRLEMVHIADNLRHETLEIEFNAETLRNPAVADYPYRRELEWLHDFAAVLEAGRGKT
DTVERVDYSFKLDGDRISIAPRKRGSPIDKVVSELMIFANAHWGGWLAEKRVPGIYRAQANGKTRMTTAPDPHVGLGVDQ
YAWSTSPLRRYVDLVNQRQLISLVRDEDPVYPPRSEALFSVVREFELAYDAYNDFQRRLERYWMLRWLIQENVDEIVASV
IREDLVRFDALPMVTRAPSVAGLAPGTRVRLAISNIDLLDISFHAEYLETVPDSTAAVP

Sequences:

>Translated_619_residues
MHVIFEEDGHFKAGSILSETEATAQVESASGKRSKVKAAAILLRFTAPAPEDVMSAAEKLGEELDADFLWEAAGSEEFGF
EQLAGEYYGHAPSPAESVALLQKLHASPIYFHKKGKGRYRPAPPETLAAAKAGLEKKRIAAERQAYLAHELAAFRLPPEY
ASLIPRILIAPDKNTLEYKALEDAAAATGLSPLRLVERCGAIPSTLDFHLMSFLLEYFPRGTGFAPVTEPLDPPELPSSP
VRAFSMDDEATTEIDDALSVAWHDDGSVRVGIHIAAPALGIAPGSELDRVARERLSTVYFPGDKITMLPETLIHHYTLGE
AHDCPALSLYVDVAADLRVLGTETRLEMVHIADNLRHETLEIEFNAETLRNPAVADYPYRRELEWLHDFAAVLEAGRGKT
DTVERVDYSFKLDGDRISIAPRKRGSPIDKVVSELMIFANAHWGGWLAEKRVPGIYRAQANGKTRMTTAPDPHVGLGVDQ
YAWSTSPLRRYVDLVNQRQLISLVRDEDPVYPPRSEALFSVVREFELAYDAYNDFQRRLERYWMLRWLIQENVDEIVASV
IREDLVRFDALPMVTRAPSVAGLAPGTRVRLAISNIDLLDISFHAEYLETVPDSTAAVP
>Mature_619_residues
MHVIFEEDGHFKAGSILSETEATAQVESASGKRSKVKAAAILLRFTAPAPEDVMSAAEKLGEELDADFLWEAAGSEEFGF
EQLAGEYYGHAPSPAESVALLQKLHASPIYFHKKGKGRYRPAPPETLAAAKAGLEKKRIAAERQAYLAHELAAFRLPPEY
ASLIPRILIAPDKNTLEYKALEDAAAATGLSPLRLVERCGAIPSTLDFHLMSFLLEYFPRGTGFAPVTEPLDPPELPSSP
VRAFSMDDEATTEIDDALSVAWHDDGSVRVGIHIAAPALGIAPGSELDRVARERLSTVYFPGDKITMLPETLIHHYTLGE
AHDCPALSLYVDVAADLRVLGTETRLEMVHIADNLRHETLEIEFNAETLRNPAVADYPYRRELEWLHDFAAVLEAGRGKT
DTVERVDYSFKLDGDRISIAPRKRGSPIDKVVSELMIFANAHWGGWLAEKRVPGIYRAQANGKTRMTTAPDPHVGLGVDQ
YAWSTSPLRRYVDLVNQRQLISLVRDEDPVYPPRSEALFSVVREFELAYDAYNDFQRRLERYWMLRWLIQENVDEIVASV
IREDLVRFDALPMVTRAPSVAGLAPGTRVRLAISNIDLLDISFHAEYLETVPDSTAAVP

Specific function: 3'-5'Exoribonuclease That Participates In An Essential Cell Function. Acts Nonspecifically On Poly(A), Poly(U) And Ribosomal RNAs. Required For The Expression Of VIrulence Genes In Enteroinvasive Strains Of E.Coli. [C]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonuclease II (RNB) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001900
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00773 RNB [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 68704; Mature: 68704

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVIFEEDGHFKAGSILSETEATAQVESASGKRSKVKAAAILLRFTAPAPEDVMSAAEKL
CEEEEECCCCEECCCHHHHHHHHHHHHHCCCCHHHHHHHEEEEEECCCCCHHHHHHHHHH
GEELDADFLWEAAGSEEFGFEQLAGEYYGHAPSPAESVALLQKLHASPIYFHKKGKGRYR
HHHCCHHHHHHCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCC
PAPPETLAAAKAGLEKKRIAAERQAYLAHELAAFRLPPEYASLIPRILIAPDKNTLEYKA
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCEEEECCCCCCEEHHH
LEDAAAATGLSPLRLVERCGAIPSTLDFHLMSFLLEYFPRGTGFAPVTEPLDPPELPSSP
HHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
VRAFSMDDEATTEIDDALSVAWHDDGSVRVGIHIAAPALGIAPGSELDRVARERLSTVYF
CEEEECCCHHHHHHHHHEEEEEECCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHCEEEE
PGDKITMLPETLIHHYTLGEAHDCPALSLYVDVAADLRVLGTETRLEMVHIADNLRHETL
CCCCEEECHHHHHHHHCCCCCCCCCEEEEEEEHHHCCEEECCHHHHEEEEHHHCCCCEEE
EIEFNAETLRNPAVADYPYRRELEWLHDFAAVLEAGRGKTDTVERVDYSFKLDGDRISIA
EEEECHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHCCEEEEECCCEEEEC
PRKRGSPIDKVVSELMIFANAHWGGWLAEKRVPGIYRAQANGKTRMTTAPDPHVGLGVDQ
CCCCCCCHHHHHHHHHHHHCCCCCCCHHHCCCCCEEEECCCCCEEECCCCCCCCCCCCHH
YAWSTSPLRRYVDLVNQRQLISLVRDEDPVYPPRSEALFSVVREFELAYDAYNDFQRRLE
HCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYWMLRWLIQENVDEIVASVIREDLVRFDALPMVTRAPSVAGLAPGTRVRLAISNIDLLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCEEEEEECCCEEEE
ISFHAEYLETVPDSTAAVP
EHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MHVIFEEDGHFKAGSILSETEATAQVESASGKRSKVKAAAILLRFTAPAPEDVMSAAEKL
CEEEEECCCCEECCCHHHHHHHHHHHHHCCCCHHHHHHHEEEEEECCCCCHHHHHHHHHH
GEELDADFLWEAAGSEEFGFEQLAGEYYGHAPSPAESVALLQKLHASPIYFHKKGKGRYR
HHHCCHHHHHHCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCC
PAPPETLAAAKAGLEKKRIAAERQAYLAHELAAFRLPPEYASLIPRILIAPDKNTLEYKA
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCEEEECCCCCCEEHHH
LEDAAAATGLSPLRLVERCGAIPSTLDFHLMSFLLEYFPRGTGFAPVTEPLDPPELPSSP
HHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
VRAFSMDDEATTEIDDALSVAWHDDGSVRVGIHIAAPALGIAPGSELDRVARERLSTVYF
CEEEECCCHHHHHHHHHEEEEEECCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHCEEEE
PGDKITMLPETLIHHYTLGEAHDCPALSLYVDVAADLRVLGTETRLEMVHIADNLRHETL
CCCCEEECHHHHHHHHCCCCCCCCCEEEEEEEHHHCCEEECCHHHHEEEEHHHCCCCEEE
EIEFNAETLRNPAVADYPYRRELEWLHDFAAVLEAGRGKTDTVERVDYSFKLDGDRISIA
EEEECHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHCCEEEEECCCEEEEC
PRKRGSPIDKVVSELMIFANAHWGGWLAEKRVPGIYRAQANGKTRMTTAPDPHVGLGVDQ
CCCCCCCHHHHHHHHHHHHCCCCCCCHHHCCCCCEEEECCCCCEEECCCCCCCCCCCCHH
YAWSTSPLRRYVDLVNQRQLISLVRDEDPVYPPRSEALFSVVREFELAYDAYNDFQRRLE
HCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYWMLRWLIQENVDEIVASVIREDLVRFDALPMVTRAPSVAGLAPGTRVRLAISNIDLLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCEEEEEECCCEEEE
ISFHAEYLETVPDSTAAVP
EHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]