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The map label for this gene is ttcA [H]

Identifier: 74318526

GI number: 74318526

Start: 2581631

End: 2582386

Strand: Direct

Name: ttcA [H]

Synonym: Tbd_2508

Alternate gene names: 74318526

Gene position: 2581631-2582386 (Clockwise)

Preceding gene: 74318525

Following gene: 74318527

Centisome position: 88.72

GC content: 65.34

Gene sequence:

>756_bases
ATGAACGACGCGCCGCAAACCGCCTGGATCAAGCCTTCGCGCTCGCTCGTCACCGCGGCTGGCCGCGCGATCGGCGACTA
CCGCATGATCCGCGATGGCGACCGCATCCTGCTCGGCCTCTCGGGCGGCAAGGACTCGCTGTCGCTCTTGCACGCACTGC
ATCACCTGCAGCAGAAAGCCCCGGTCAAGTTCGAGCTGCTGGCGTGCACGGTCGACCCGCAGTCCGACCAGTTCGACCCC
TCGCCGCTTGCGCCCTACATGGCCGCGCTCGGCGTGCCGTATTTTCTCGAGTCCCAACCCATACTCGAAGATGCGCAGAG
GACGCTGACCAAGGACACCGATTCCTACTGCGCCTATTGTTCCAGGATGCGCCGCGGCATTCTCTACCGCGTCGCCCGCG
AGCAGCGCTGCAACGTGATCGCGCTCGCGCAGCATCTCGACGATCTCGCCGAGACGCTGATGATGTCGATGTTCTTTGGC
GGCAAGCTGAGGACCATGTCGCCGCATTATCTGAACGACGCCGGCGACCTCAGGATCATCCGCCCCCTCGCCTACGCGCG
CGAACGCCAGACCCGCGCATTCGCGGCGGACGCCGGCCTGCCCGTCATTTTCGAGAACTGCCCGGCCTGCTTCGCCAAGC
CGCAGCAGCGCTACGCAATGAAGCAGATGCTGGCCGAGCAGGAGAAGCAGCATCCGCGCATTTTCAACAGCCTGCTCACG
GCAATGCGGCCGCTGATGGGAGAGCCGCCCGCCTAG

Upstream 100 bases:

>100_bases
TCGTACTCGAAGGCGGACGCATCGTGGAAACCGGCGCCCACGCCGACCTGCTCGCGAAGCAGGGCCGCTACGCGCAACTC
CACGCGCTGCAGTTTTCGCA

Downstream 100 bases:

>100_bases
CGCGGCCGGTTGCGATCCGGCGCCAGAAACGCGCCGGAGCTCGGACGGGTTTTGGTCGCACCGCTTTAGCCGTAAAATCA
ACCCTTTGTTTTATTTGACG

Product: putative cell cycle control ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MNDAPQTAWIKPSRSLVTAAGRAIGDYRMIRDGDRILLGLSGGKDSLSLLHALHHLQQKAPVKFELLACTVDPQSDQFDP
SPLAPYMAALGVPYFLESQPILEDAQRTLTKDTDSYCAYCSRMRRGILYRVAREQRCNVIALAQHLDDLAETLMMSMFFG
GKLRTMSPHYLNDAGDLRIIRPLAYARERQTRAFAADAGLPVIFENCPACFAKPQQRYAMKQMLAEQEKQHPRIFNSLLT
AMRPLMGEPPA

Sequences:

>Translated_251_residues
MNDAPQTAWIKPSRSLVTAAGRAIGDYRMIRDGDRILLGLSGGKDSLSLLHALHHLQQKAPVKFELLACTVDPQSDQFDP
SPLAPYMAALGVPYFLESQPILEDAQRTLTKDTDSYCAYCSRMRRGILYRVAREQRCNVIALAQHLDDLAETLMMSMFFG
GKLRTMSPHYLNDAGDLRIIRPLAYARERQTRAFAADAGLPVIFENCPACFAKPQQRYAMKQMLAEQEKQHPRIFNSLLT
AMRPLMGEPPA
>Mature_251_residues
MNDAPQTAWIKPSRSLVTAAGRAIGDYRMIRDGDRILLGLSGGKDSLSLLHALHHLQQKAPVKFELLACTVDPQSDQFDP
SPLAPYMAALGVPYFLESQPILEDAQRTLTKDTDSYCAYCSRMRRGILYRVAREQRCNVIALAQHLDDLAETLMMSMFFG
GKLRTMSPHYLNDAGDLRIIRPLAYARERQTRAFAADAGLPVIFENCPACFAKPQQRYAMKQMLAEQEKQHPRIFNSLLT
AMRPLMGEPPA

Specific function: Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) [H]

COG id: COG0037

COG function: function code D; Predicted ATPase of the PP-loop superfamily implicated in cell cycle control

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TtcA family [H]

Homologues:

Organism=Escherichia coli, GI1787606, Length=241, Percent_Identity=38.5892116182573, Blast_Score=172, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI193211090, Length=242, Percent_Identity=47.1074380165289, Blast_Score=220, Evalue=4e-58,
Organism=Caenorhabditis elegans, GI17540090, Length=237, Percent_Identity=25.7383966244726, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012089
- InterPro:   IPR014729
- InterPro:   IPR011063 [H]

Pfam domain/function: PF01171 ATP_bind_3 [H]

EC number: NA

Molecular weight: Translated: 28171; Mature: 28171

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDAPQTAWIKPSRSLVTAAGRAIGDYRMIRDGDRILLGLSGGKDSLSLLHALHHLQQKA
CCCCCCCCEECCCHHHHHHHHHHHHHHHHEECCCEEEEEECCCHHHHHHHHHHHHHHHCC
PVKFELLACTVDPQSDQFDPSPLAPYMAALGVPYFLESQPILEDAQRTLTKDTDSYCAYC
CCEEEEEEEEECCCCCCCCCCCHHHHHHHCCCCHHHCCCCHHHHHHHHHHCCCHHHHHHH
SRMRRGILYRVAREQRCNVIALAQHLDDLAETLMMSMFFGGKLRTMSPHYLNDAGDLRII
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCEEEH
RPLAYARERQTRAFAADAGLPVIFENCPACFAKPQQRYAMKQMLAEQEKQHPRIFNSLLT
HHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHH
AMRPLMGEPPA
HHHHHCCCCCC
>Mature Secondary Structure
MNDAPQTAWIKPSRSLVTAAGRAIGDYRMIRDGDRILLGLSGGKDSLSLLHALHHLQQKA
CCCCCCCCEECCCHHHHHHHHHHHHHHHHEECCCEEEEEECCCHHHHHHHHHHHHHHHCC
PVKFELLACTVDPQSDQFDPSPLAPYMAALGVPYFLESQPILEDAQRTLTKDTDSYCAYC
CCEEEEEEEEECCCCCCCCCCCHHHHHHHCCCCHHHCCCCHHHHHHHHHHCCCHHHHHHH
SRMRRGILYRVAREQRCNVIALAQHLDDLAETLMMSMFFGGKLRTMSPHYLNDAGDLRII
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCEEEH
RPLAYARERQTRAFAADAGLPVIFENCPACFAKPQQRYAMKQMLAEQEKQHPRIFNSLLT
HHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHH
AMRPLMGEPPA
HHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA