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The map label for this gene is pucG [H]

Identifier: 74318527

GI number: 74318527

Start: 2582510

End: 2583643

Strand: Direct

Name: pucG [H]

Synonym: Tbd_2509

Alternate gene names: 74318527

Gene position: 2582510-2583643 (Clockwise)

Preceding gene: 74318526

Following gene: 74318530

Centisome position: 88.75

GC content: 65.78

Gene sequence:

>1134_bases
ATGACGGCTTCCTTCCTCCCTCCCAAGCGCATCCTCATGGGTCCCGGCCCGTCCGACGTACCGCAGCGCGTGCTCGACGC
GATGGCGCGTCCGACGATCGGCCACCTCGACCCGGCCTTCGTCGACCTGATGGAGCAGATCAAGGCCATGTTGCGCATGG
CGTTCCGGACCGAGAACGCGCTGACCTTCCCGGTTTCGGCCCCCGGTTCGGCAGGGATGGAGATGTGCTTCGTCAACCTC
GTCGAGCCCGGCGACAAGGTCATCGTCTGCCGCAACGGCGTGTTCGGCGGACGCATGCTCGAGAACGTCAAGCGCACGGG
CGGCGTGCCGGTGGTCGTCGATGACGCCTGGGGCGCAGCGGTCGACCCGCAAAAGGTGCGCGATGCCTTCAAGTCGAACC
CGGACGCCAAGGTGCTCGCCTTCGTGCACGCCGAGACGTCGACCGGCGCGCAGTCCGACGCTGCGGCCCTGGCGAAGATC
GCGCAGGAAGCCGGCGCGCTCACGATCTTGGACTGCGTCACGAGCCTGGGCGGAACGCCCGTGCTGCTCGACCAGTGGCG
CATCGACGCCGCTTACTCCGGCAGCCAGAAGTGCCTGTCGTGCACGCCGGGCCTCTCGCCGGTCTCGTTCTCGGAACGTG
CCATCGAAAAGATCAAAGCACGCAAGACGCCCGTGCAGAGCTGGTTCCTCGACCTCAATCTCGTGCTCGGCTACTGGCAG
TCGGCGGGCAAACGCACCTATCACCACACCGCGCCGATCAATCCGATGTATGGCCTGCACGAGTCGCTGGTGATGCTCGA
GGAGGAAGGCCTGGAGAATTCCTGGGCGCGCCATCGTGCGATGCACGAGAAGCTGAAGGCTGGCCTCGAAGGGCTCGGCC
TGCGTTATGTCGTCGAGGAAAGCGCCCGCCTGCCGCAGCTCAACTCGATCTACGTGCCTGAAGGCGTCGACGAAGCCGCG
ATCCGCAGCCGGCTCCTGAGCGAGTTCAATCTCGAAATCGGTGCCGGACTCGGCGACATGGCCGGCAAGATCTGGCGCAT
CGGCCTGATGGGCTATTCGGCCAAGCAGGCGAACATCGACCTTTGCCTGCAGGCGCTGAGTGCCTGCCTCGAGAAAAGCG
CAGCCGGGGCTTGA

Upstream 100 bases:

>100_bases
CAGAAACGCGCCGGAGCTCGGACGGGTTTTGGTCGCACCGCTTTAGCCGTAAAATCAACCCTTTGTTTTATTTGACGTTT
TCCACATCGAGACCAAGGTT

Downstream 100 bases:

>100_bases
GGTCGGCCCGGCGGCGCGTCGCTATTCAAGCGGCGAATGAGGACGGCCCCTGCGCGGGGCCGTAGTCATATCAGCCCCAT
CAGCAGCAGCACGATCAGAA

Product: alanine-glyoxylate aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MTASFLPPKRILMGPGPSDVPQRVLDAMARPTIGHLDPAFVDLMEQIKAMLRMAFRTENALTFPVSAPGSAGMEMCFVNL
VEPGDKVIVCRNGVFGGRMLENVKRTGGVPVVVDDAWGAAVDPQKVRDAFKSNPDAKVLAFVHAETSTGAQSDAAALAKI
AQEAGALTILDCVTSLGGTPVLLDQWRIDAAYSGSQKCLSCTPGLSPVSFSERAIEKIKARKTPVQSWFLDLNLVLGYWQ
SAGKRTYHHTAPINPMYGLHESLVMLEEEGLENSWARHRAMHEKLKAGLEGLGLRYVVEESARLPQLNSIYVPEGVDEAA
IRSRLLSEFNLEIGAGLGDMAGKIWRIGLMGYSAKQANIDLCLQALSACLEKSAAGA

Sequences:

>Translated_377_residues
MTASFLPPKRILMGPGPSDVPQRVLDAMARPTIGHLDPAFVDLMEQIKAMLRMAFRTENALTFPVSAPGSAGMEMCFVNL
VEPGDKVIVCRNGVFGGRMLENVKRTGGVPVVVDDAWGAAVDPQKVRDAFKSNPDAKVLAFVHAETSTGAQSDAAALAKI
AQEAGALTILDCVTSLGGTPVLLDQWRIDAAYSGSQKCLSCTPGLSPVSFSERAIEKIKARKTPVQSWFLDLNLVLGYWQ
SAGKRTYHHTAPINPMYGLHESLVMLEEEGLENSWARHRAMHEKLKAGLEGLGLRYVVEESARLPQLNSIYVPEGVDEAA
IRSRLLSEFNLEIGAGLGDMAGKIWRIGLMGYSAKQANIDLCLQALSACLEKSAAGA
>Mature_376_residues
TASFLPPKRILMGPGPSDVPQRVLDAMARPTIGHLDPAFVDLMEQIKAMLRMAFRTENALTFPVSAPGSAGMEMCFVNLV
EPGDKVIVCRNGVFGGRMLENVKRTGGVPVVVDDAWGAAVDPQKVRDAFKSNPDAKVLAFVHAETSTGAQSDAAALAKIA
QEAGALTILDCVTSLGGTPVLLDQWRIDAAYSGSQKCLSCTPGLSPVSFSERAIEKIKARKTPVQSWFLDLNLVLGYWQS
AGKRTYHHTAPINPMYGLHESLVMLEEEGLENSWARHRAMHEKLKAGLEGLGLRYVVEESARLPQLNSIYVPEGVDEAAI
RSRLLSEFNLEIGAGLGDMAGKIWRIGLMGYSAKQANIDLCLQALSACLEKSAAGA

Specific function: Could encode ureidoglycolase or L-alanine:glyoxylate aminotransferase, or perhaps both activities [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=366, Percent_Identity=36.8852459016393, Blast_Score=250, Evalue=1e-66,
Organism=Caenorhabditis elegans, GI17536281, Length=373, Percent_Identity=39.142091152815, Blast_Score=256, Evalue=1e-68,
Organism=Saccharomyces cerevisiae, GI6321079, Length=385, Percent_Identity=27.2727272727273, Blast_Score=107, Evalue=3e-24,
Organism=Drosophila melanogaster, GI17530823, Length=372, Percent_Identity=36.8279569892473, Blast_Score=259, Evalue=2e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 40619; Mature: 40488

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASFLPPKRILMGPGPSDVPQRVLDAMARPTIGHLDPAFVDLMEQIKAMLRMAFRTENA
CCCCCCCCHHEEECCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
LTFPVSAPGSAGMEMCFVNLVEPGDKVIVCRNGVFGGRMLENVKRTGGVPVVVDDAWGAA
EEEECCCCCCCCHHHHEEEEECCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCC
VDPQKVRDAFKSNPDAKVLAFVHAETSTGAQSDAAALAKIAQEAGALTILDCVTSLGGTP
CCHHHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCE
VLLDQWRIDAAYSGSQKCLSCTPGLSPVSFSERAIEKIKARKTPVQSWFLDLNLVLGYWQ
EEEECEEECCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
SAGKRTYHHTAPINPMYGLHESLVMLEEEGLENSWARHRAMHEKLKAGLEGLGLRYVVEE
HCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEHH
SARLPQLNSIYVPEGVDEAAIRSRLLSEFNLEIGAGLGDMAGKIWRIGLMGYSAKQANID
CCCCCCCCCEECCCCCCHHHHHHHHHHHHCHHHCCCCHHHHHHHEEEEEECCCCCCCCHH
LCLQALSACLEKSAAGA
HHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TASFLPPKRILMGPGPSDVPQRVLDAMARPTIGHLDPAFVDLMEQIKAMLRMAFRTENA
CCCCCCCHHEEECCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
LTFPVSAPGSAGMEMCFVNLVEPGDKVIVCRNGVFGGRMLENVKRTGGVPVVVDDAWGAA
EEEECCCCCCCCHHHHEEEEECCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCC
VDPQKVRDAFKSNPDAKVLAFVHAETSTGAQSDAAALAKIAQEAGALTILDCVTSLGGTP
CCHHHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCE
VLLDQWRIDAAYSGSQKCLSCTPGLSPVSFSERAIEKIKARKTPVQSWFLDLNLVLGYWQ
EEEECEEECCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
SAGKRTYHHTAPINPMYGLHESLVMLEEEGLENSWARHRAMHEKLKAGLEGLGLRYVVEE
HCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEHH
SARLPQLNSIYVPEGVDEAAIRSRLLSEFNLEIGAGLGDMAGKIWRIGLMGYSAKQANID
CCCCCCCCCEECCCCCCHHHHHHHHHHHHCHHHCCCCHHHHHHHEEEEEECCCCCCCCHH
LCLQALSACLEKSAAGA
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 11344136 [H]