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The map label for this gene is pyrD [H]

Identifier: 74318485

GI number: 74318485

Start: 2539408

End: 2540418

Strand: Reverse

Name: pyrD [H]

Synonym: Tbd_2467

Alternate gene names: 74318485

Gene position: 2540418-2539408 (Counterclockwise)

Preceding gene: 74318486

Following gene: 74318473

Centisome position: 87.31

GC content: 66.37

Gene sequence:

>1011_bases
ATGATCGACCTATCCACCGACTACCTCGGCCTGAAACTGAAAAATCCGCTCGTGCCCTCGGCGTCGCCGCTGTCGCGCAA
CCTCGACAACGCCCTGCGCCTCGAGGACGCGGGTGCGGCGGCGCTCGTGATGTATTCGCTGTTCGAGGAGGAACTGCGGG
CGGAAGACGCGATGCTCGACCGCTTTCTGACTTGCCCCGACTTCGGCCACAGCGAAGCGGCCAACTTCCTGCCCAGCGCG
CCGTTCGAGGACGGGCTCGAACGCTATGTGTCGCAGCTGCAGAAGCTCAAGGCACGGCTCGGCATCCCCGTCATCGCGAG
CCTCAACGGCGTGTCGCGCTCGGGCTGGGTCGAACTCGGCCGTGCGCTCGAGGAGGCCGGCGCCGACGCGCTCGAACTCA
ACGTCTATCACGTCGCCGCCGAGATGTGGGAGAACGGCGAGGCGGTCGAGGCCCGTTATCTGAGCCTGCTGCGCGATCTG
CGTCATGCCGTGAAGCTGCCGATCGTGATGAAGCTGTCGCCGTTCTTCTCGTCGCTGCCGAACTTCGTCAAGCGGCTCGA
ACACGCGGGGGCGCAGGGGGTCGTGCTATTCAACCGCTTCTATCAGCCCGACATCGACCTTGACACGCTCTGCGTCGTCG
ACCGCCTGCACCTCTCGTATCCCGACGAAGCGCTCTTGCGCATCCGCTGGCTGTCGATCCTGCACGGGCGCACCGGCCTC
ACGCTCGCCGCCACCGGCGGCGTCCACAGCCACGACGAAGCGCTCAAGATGCTCCTGGTCGGCGCTGACGTGATTCACCT
CGCGTCCTGCCTGCTTCAGCACGGCCCCGCCAGGCTGACGCGGATACTGCAGGACATCGAGCGCTGGATGGGCGAGCGCG
ACTACGCGTCGGTCGCGCAGCTGAAGGGCAGCATGAGTCAGAAGAACCTGCTCGACCCGGCAGCGATGGCGCGGCTCTCC
TATCTGCGCGTGCTCGACAGCTTCTCGCCGCAGCCCGGCGTGTGGTCCTGA

Upstream 100 bases:

>100_bases
CGTTTTCTCGCGCAGGCGCAGCAGGACGCCGAGCGCCGCTTCAAGCTGTACCAGGAAATGACGTTAAACCCAGACAATAA
ACCTCAAGCGGGACCCTGAC

Downstream 100 bases:

>100_bases
CGCTGCGCACCTGATGGCTGCGCGCTCGGGGCTCGCGCGTCGGGTCGTGCGGTCGCGTGGACCGCTGGGCAGTCGCTAAA
GGTCGCCGCCGCGCAGATAG

Product: dihydroorotate dehydrogenase 2

Products: NA

Alternate protein names: DHOdehase; DHOD; DHODase; Dihydroorotate oxidase [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MIDLSTDYLGLKLKNPLVPSASPLSRNLDNALRLEDAGAAALVMYSLFEEELRAEDAMLDRFLTCPDFGHSEAANFLPSA
PFEDGLERYVSQLQKLKARLGIPVIASLNGVSRSGWVELGRALEEAGADALELNVYHVAAEMWENGEAVEARYLSLLRDL
RHAVKLPIVMKLSPFFSSLPNFVKRLEHAGAQGVVLFNRFYQPDIDLDTLCVVDRLHLSYPDEALLRIRWLSILHGRTGL
TLAATGGVHSHDEALKMLLVGADVIHLASCLLQHGPARLTRILQDIERWMGERDYASVAQLKGSMSQKNLLDPAAMARLS
YLRVLDSFSPQPGVWS

Sequences:

>Translated_336_residues
MIDLSTDYLGLKLKNPLVPSASPLSRNLDNALRLEDAGAAALVMYSLFEEELRAEDAMLDRFLTCPDFGHSEAANFLPSA
PFEDGLERYVSQLQKLKARLGIPVIASLNGVSRSGWVELGRALEEAGADALELNVYHVAAEMWENGEAVEARYLSLLRDL
RHAVKLPIVMKLSPFFSSLPNFVKRLEHAGAQGVVLFNRFYQPDIDLDTLCVVDRLHLSYPDEALLRIRWLSILHGRTGL
TLAATGGVHSHDEALKMLLVGADVIHLASCLLQHGPARLTRILQDIERWMGERDYASVAQLKGSMSQKNLLDPAAMARLS
YLRVLDSFSPQPGVWS
>Mature_336_residues
MIDLSTDYLGLKLKNPLVPSASPLSRNLDNALRLEDAGAAALVMYSLFEEELRAEDAMLDRFLTCPDFGHSEAANFLPSA
PFEDGLERYVSQLQKLKARLGIPVIASLNGVSRSGWVELGRALEEAGADALELNVYHVAAEMWENGEAVEARYLSLLRDL
RHAVKLPIVMKLSPFFSSLPNFVKRLEHAGAQGVVLFNRFYQPDIDLDTLCVVDRLHLSYPDEALLRIRWLSILHGRTGL
TLAATGGVHSHDEALKMLLVGADVIHLASCLLQHGPARLTRILQDIERWMGERDYASVAQLKGSMSQKNLLDPAAMARLS
YLRVLDSFSPQPGVWS

Specific function: Unknown

COG id: COG0167

COG function: function code F; Dihydroorotate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005720
- InterPro:   IPR012135
- InterPro:   IPR001295 [H]

Pfam domain/function: PF01180 DHO_dh [H]

EC number: =1.3.3.1 [H]

Molecular weight: Translated: 37240; Mature: 37240

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDLSTDYLGLKLKNPLVPSASPLSRNLDNALRLEDAGAAALVMYSLFEEELRAEDAMLD
CCCCCCCCCCEEECCCCCCCCCHHHHCHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHH
RFLTCPDFGHSEAANFLPSAPFEDGLERYVSQLQKLKARLGIPVIASLNGVSRSGWVELG
HHHCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHH
RALEEAGADALELNVYHVAAEMWENGEAVEARYLSLLRDLRHAVKLPIVMKLSPFFSSLP
HHHHHCCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHEEECHHHHHHH
NFVKRLEHAGAQGVVLFNRFYQPDIDLDTLCVVDRLHLSYPDEALLRIRWLSILHGRTGL
HHHHHHHHCCCCCEEEEHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCE
TLAATGGVHSHDEALKMLLVGADVIHLASCLLQHGPARLTRILQDIERWMGERDYASVAQ
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHH
LKGSMSQKNLLDPAAMARLSYLRVLDSFSPQPGVWS
HHHCHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MIDLSTDYLGLKLKNPLVPSASPLSRNLDNALRLEDAGAAALVMYSLFEEELRAEDAMLD
CCCCCCCCCCEEECCCCCCCCCHHHHCHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHH
RFLTCPDFGHSEAANFLPSAPFEDGLERYVSQLQKLKARLGIPVIASLNGVSRSGWVELG
HHHCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHH
RALEEAGADALELNVYHVAAEMWENGEAVEARYLSLLRDLRHAVKLPIVMKLSPFFSSLP
HHHHHCCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHEEECHHHHHHH
NFVKRLEHAGAQGVVLFNRFYQPDIDLDTLCVVDRLHLSYPDEALLRIRWLSILHGRTGL
HHHHHHHHCCCCCEEEEHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCE
TLAATGGVHSHDEALKMLLVGADVIHLASCLLQHGPARLTRILQDIERWMGERDYASVAQ
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHH
LKGSMSQKNLLDPAAMARLSYLRVLDSFSPQPGVWS
HHHCHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11029001 [H]