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The map label for this gene is aer [H]

Identifier: 74318424

GI number: 74318424

Start: 2477203

End: 2478903

Strand: Reverse

Name: aer [H]

Synonym: Tbd_2406

Alternate gene names: 74318424

Gene position: 2478903-2477203 (Counterclockwise)

Preceding gene: 74318425

Following gene: 74318423

Centisome position: 85.19

GC content: 68.55

Gene sequence:

>1701_bases
ATGCGCGTCAATCTGCCCGTTACGAACCATGCCTACGAACTGAGCGAGGGCGACACGCTCGTTTCCAAGACCGATCGCGA
GGGGGTGATCGTCTACGCCAACCCGGCGTTCGTCGAGGCGAGCGGCTACACCGAGGCGGAACTCATCGGCCAGCCGCACA
ACCTCGTTCGCCACCCGGACATGCCGCCGGAGGCCTTTGCCGACCTCTGGTCAACCCTGCAGGCGGGGCTGCCGTGGACC
GGGCTCGTGAAGAACCGGCGCAAGAACGGCGATTTCTACTGGGTCCAGGCGAACGTCACTCCGGTCCGCGAAGATGGCGT
TCTGAGCGGCTTCCTGTCGGTACGCACCAGACCGACCCGCGAACAGATCGCCGAGGCGGAGCAGCTGTATCGGCAGTTGC
GCGAAGGGTCGCCGAAGCGCCTCGAAATCCGCCGTGGCGTCGTGTCACGCGGCGGCCTGGTCGGTCGTCTGCTGGCGTTC
CGCCGCATCCCGGTCAATACGCGCATCCTGCTGAGCACCGCAATCGGCGCGACGCTGATGCTCGCGGGCGGGGTGTTCGG
CTGGTACGAGACGAGCGCGCTCGCCCGCGCCGCCGGCGTCGACAGCGTCATCCCGACCGTCGTGGCGGCTGCCGGCGCGG
TCGGTGCCGTGCTGACGCTGCTGTTCGGCTACTTCATTTCGCGCACGATCCTGCGCCCGCTCGACCGCGCGCTGGGTGTC
GCCCGTGCGATCGCGGGCGGTGACCTGTCGCACCGCTTCGAAGTGACGGCGTGGGAGGAAACCGGGCAACTGATGCTCGC
GCTGCAGCAGATGACGGCGAACATGGTCGCCGTGCTGAGCGACATCGGTTCCAACGTCGGCAGTATTCGTGTCGCAACGG
GCGAGATCGCGGCCGGTAACGCGGATCTGGCAGGACGGACCGAATCGCAGGCGTCGAATCTGGAACAGACCGCGGCGTCG
ATGGAGGAACTCACGGGTACGGTCAAGCAGAACGCCGAGCACGCGCGCCACGCCAACCAGCTCGCCGACGCGGCGACCGA
TATCGCAGTCAAGGGCGGCGGCGTCGTCAATCAGGTCGTCGACACGATGACGTCGATCAAGGCGAGTTCGGCGCGCATCT
CCGACATCATCAGCGTCATCGACGGGATCGCGTTCCAGACCAACATCCTCGCCCTGAACGCGGCGGTCGAGGCGGCGCGC
GCCGGCGAGCAGGGGCGGGGCTTCGCCGTCGTCGCCACCGAGGTCAGGCATCTCGCGCAGCGCTCGACGCTCGCCGCGCG
GGAAATCAAGGACCTGATCGGCGACTCGGTCGAAAAAGTTGAGCAGGGCGCCAAACTCGTCGACCAGGCCGGGGAGGCGA
TGGACGATATCGTCACCTCGGTCGAACTCGTCGCCGGGATCGTCGGCGGCATCGCGACCGCGAGCCAGGAGCAGCACGCG
GGCATCGAGCAGGTCAACGAGGCGGTCGGGCAGATGGACGAAATCACGCAGCAAAACGCGGCGCTCGTCGAGGAGGCGGC
CGCCGCCGCGCAAAGCCTGCACGAACAGGCAGACCGGCTCGCTCAGGCTGTCGGGGTGTTCAGCCTCGGGCGAGGGCGCG
CGCGCTCCCAGCCGGCAGGAACGCGCCCCGCGCCGCGGCTGATGCCGGCCGCGTCACCTCAGAAGCGTCGCGGCACCGCC
GCGCGGGCAATCGGCCGCTGA

Upstream 100 bases:

>100_bases
GCGGGTCCGCCCCGACCGGCATGCCAACGCTCCTCGGTTTTGCTCACGCGTGAAGCGGGCCGGCTGCGCTCCAGATAACA
TTCACTACACATCGCCAGCC

Downstream 100 bases:

>100_bases
GTTCGCCGCCTTTGCGGCTGCGCGGCATGATCTGGCGACCCCGCTCCGACCCCGCGGCGCGCGTCGCGGCGAGTTTCTAC
ACCCCTCGTCCGGCGAGCGA

Product: methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 566; Mature: 566

Protein sequence:

>566_residues
MRVNLPVTNHAYELSEGDTLVSKTDREGVIVYANPAFVEASGYTEAELIGQPHNLVRHPDMPPEAFADLWSTLQAGLPWT
GLVKNRRKNGDFYWVQANVTPVREDGVLSGFLSVRTRPTREQIAEAEQLYRQLREGSPKRLEIRRGVVSRGGLVGRLLAF
RRIPVNTRILLSTAIGATLMLAGGVFGWYETSALARAAGVDSVIPTVVAAAGAVGAVLTLLFGYFISRTILRPLDRALGV
ARAIAGGDLSHRFEVTAWEETGQLMLALQQMTANMVAVLSDIGSNVGSIRVATGEIAAGNADLAGRTESQASNLEQTAAS
MEELTGTVKQNAEHARHANQLADAATDIAVKGGGVVNQVVDTMTSIKASSARISDIISVIDGIAFQTNILALNAAVEAAR
AGEQGRGFAVVATEVRHLAQRSTLAAREIKDLIGDSVEKVEQGAKLVDQAGEAMDDIVTSVELVAGIVGGIATASQEQHA
GIEQVNEAVGQMDEITQQNAALVEEAAAAAQSLHEQADRLAQAVGVFSLGRGRARSQPAGTRPAPRLMPAASPQKRRGTA
ARAIGR

Sequences:

>Translated_566_residues
MRVNLPVTNHAYELSEGDTLVSKTDREGVIVYANPAFVEASGYTEAELIGQPHNLVRHPDMPPEAFADLWSTLQAGLPWT
GLVKNRRKNGDFYWVQANVTPVREDGVLSGFLSVRTRPTREQIAEAEQLYRQLREGSPKRLEIRRGVVSRGGLVGRLLAF
RRIPVNTRILLSTAIGATLMLAGGVFGWYETSALARAAGVDSVIPTVVAAAGAVGAVLTLLFGYFISRTILRPLDRALGV
ARAIAGGDLSHRFEVTAWEETGQLMLALQQMTANMVAVLSDIGSNVGSIRVATGEIAAGNADLAGRTESQASNLEQTAAS
MEELTGTVKQNAEHARHANQLADAATDIAVKGGGVVNQVVDTMTSIKASSARISDIISVIDGIAFQTNILALNAAVEAAR
AGEQGRGFAVVATEVRHLAQRSTLAAREIKDLIGDSVEKVEQGAKLVDQAGEAMDDIVTSVELVAGIVGGIATASQEQHA
GIEQVNEAVGQMDEITQQNAALVEEAAAAAQSLHEQADRLAQAVGVFSLGRGRARSQPAGTRPAPRLMPAASPQKRRGTA
ARAIGR
>Mature_566_residues
MRVNLPVTNHAYELSEGDTLVSKTDREGVIVYANPAFVEASGYTEAELIGQPHNLVRHPDMPPEAFADLWSTLQAGLPWT
GLVKNRRKNGDFYWVQANVTPVREDGVLSGFLSVRTRPTREQIAEAEQLYRQLREGSPKRLEIRRGVVSRGGLVGRLLAF
RRIPVNTRILLSTAIGATLMLAGGVFGWYETSALARAAGVDSVIPTVVAAAGAVGAVLTLLFGYFISRTILRPLDRALGV
ARAIAGGDLSHRFEVTAWEETGQLMLALQQMTANMVAVLSDIGSNVGSIRVATGEIAAGNADLAGRTESQASNLEQTAAS
MEELTGTVKQNAEHARHANQLADAATDIAVKGGGVVNQVVDTMTSIKASSARISDIISVIDGIAFQTNILALNAAVEAAR
AGEQGRGFAVVATEVRHLAQRSTLAAREIKDLIGDSVEKVEQGAKLVDQAGEAMDDIVTSVELVAGIVGGIATASQEQHA
GIEQVNEAVGQMDEITQQNAALVEEAAAAAQSLHEQADRLAQAVGVFSLGRGRARSQPAGTRPAPRLMPAASPQKRRGTA
ARAIGR

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=521, Percent_Identity=40.8829174664108, Blast_Score=370, Evalue=1e-103,
Organism=Escherichia coli, GI1788195, Length=334, Percent_Identity=54.7904191616767, Blast_Score=296, Evalue=2e-81,
Organism=Escherichia coli, GI2367378, Length=346, Percent_Identity=54.3352601156069, Blast_Score=293, Evalue=1e-80,
Organism=Escherichia coli, GI1787690, Length=324, Percent_Identity=52.1604938271605, Blast_Score=286, Evalue=2e-78,
Organism=Escherichia coli, GI1788194, Length=358, Percent_Identity=48.8826815642458, Blast_Score=282, Evalue=3e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 59858; Mature: 59858

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVNLPVTNHAYELSEGDTLVSKTDREGVIVYANPAFVEASGYTEAELIGQPHNLVRHPD
CEECCCCCCCCEECCCCCEEHCCCCCCCEEEEECCCEEECCCCCHHHHCCCCHHHCCCCC
MPPEAFADLWSTLQAGLPWTGLVKNRRKNGDFYWVQANVTPVREDGVLSGFLSVRTRPTR
CCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCH
EQIAEAEQLYRQLREGSPKRLEIRRGVVSRGGLVGRLLAFRRIPVNTRILLSTAIGATLM
HHHHHHHHHHHHHHCCCCCEEHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHH
LAGGVFGWYETSALARAAGVDSVIPTVVAAAGAVGAVLTLLFGYFISRTILRPLDRALGV
HHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARAIAGGDLSHRFEVTAWEETGQLMLALQQMTANMVAVLSDIGSNVGSIRVATGEIAAGN
HHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCEECCC
ADLAGRTESQASNLEQTAASMEELTGTVKQNAEHARHANQLADAATDIAVKGGGVVNQVV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHH
DTMTSIKASSARISDIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVATEVRHLAQ
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHH
RSTLAAREIKDLIGDSVEKVEQGAKLVDQAGEAMDDIVTSVELVAGIVGGIATASQEQHA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHC
GIEQVNEAVGQMDEITQQNAALVEEAAAAAQSLHEQADRLAQAVGVFSLGRGRARSQPAG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
TRPAPRLMPAASPQKRRGTAARAIGR
CCCCCCCCCCCCCHHHCCHHHHHCCC
>Mature Secondary Structure
MRVNLPVTNHAYELSEGDTLVSKTDREGVIVYANPAFVEASGYTEAELIGQPHNLVRHPD
CEECCCCCCCCEECCCCCEEHCCCCCCCEEEEECCCEEECCCCCHHHHCCCCHHHCCCCC
MPPEAFADLWSTLQAGLPWTGLVKNRRKNGDFYWVQANVTPVREDGVLSGFLSVRTRPTR
CCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCH
EQIAEAEQLYRQLREGSPKRLEIRRGVVSRGGLVGRLLAFRRIPVNTRILLSTAIGATLM
HHHHHHHHHHHHHHCCCCCEEHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHH
LAGGVFGWYETSALARAAGVDSVIPTVVAAAGAVGAVLTLLFGYFISRTILRPLDRALGV
HHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARAIAGGDLSHRFEVTAWEETGQLMLALQQMTANMVAVLSDIGSNVGSIRVATGEIAAGN
HHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCEECCC
ADLAGRTESQASNLEQTAASMEELTGTVKQNAEHARHANQLADAATDIAVKGGGVVNQVV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHH
DTMTSIKASSARISDIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVATEVRHLAQ
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHH
RSTLAAREIKDLIGDSVEKVEQGAKLVDQAGEAMDDIVTSVELVAGIVGGIATASQEQHA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHC
GIEQVNEAVGQMDEITQQNAALVEEAAAAAQSLHEQADRLAQAVGVFSLGRGRARSQPAG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
TRPAPRLMPAASPQKRRGTAARAIGR
CCCCCCCCCCCCCHHHCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]